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MGIDIRHADDRARTRISWLDSRHSFSFGEHYDPHNTHHGLLLVNNDDIVLPGAGFETHPHRDMEIITWVL HGSLVHQDSEGNAGVIYPGLAQRMSAGTGILHSEKNDSWRLSGERHTDPVRFIQMWVTPDDSGIDPGYQQ REIGNELLSGGLVTVASGMPQHRDQTAITIAQKNAALHAARIAAGDSVELPAAQFVHLFVPRGAITVEAV GELTEGDALRLTDIGAVRVTAIRDAEILVWEMHTRLGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4561 | - | - | 100% (248) | hypothetical protein MAB_4561 |
| M. abscessus ATCC 19977 | MAB_1564c | - | 3e-55 | 45.04% (242) | putative pirin-like protein |
| M. abscessus ATCC 19977 | MAB_2446c | - | 3e-12 | 31.66% (199) | putative pirin-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0187c | - | 2e-84 | 61.22% (245) | hypothetical protein Mb0187c |
| M. gilvum PYR-GCK | Mflv_0696 | - | 1e-104 | 70.33% (246) | pirin domain-containing protein |
| M. tuberculosis H37Rv | Rv0181c | - | 2e-84 | 61.22% (245) | hypothetical protein Rv0181c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0424 | - | 4e-86 | 60.82% (245) | hypothetical protein MMAR_0424 |
| M. avium 104 | MAV_5002 | - | 3e-87 | 62.35% (247) | YhhW protein |
| M. smegmatis MC2 155 | MSMEG_0215 | - | 2e-79 | 59.92% (247) | YhhW family protein |
| M. thermoresistible (build 8) | TH_0606 | - | 1e-100 | 69.64% (247) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4766 | - | 1e-10 | 32.39% (176) | hypothetical protein MUL_4766 |
| M. vanbaalenii PYR-1 | Mvan_0147 | - | 1e-101 | 68.70% (246) | pirin domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0187c|M.bovis_AF2122/97 ----MTATVEIRRAAD----------RAVTTTSWLKSRHSFSFGDHYDPD
Rv0181c|M.tuberculosis_H37Rv ----MTATVEIRRAAD----------RAVTTTSWLKSRHSFSFGDHYDPD
MMAR_0424|M.marinum_M ----MPATVQIRRAAD----------RAVTTTSWLTSRHSFSFGDHYDPD
MAV_5002|M.avium_104 ----MSAGFEIRRAAT----------RAVTTTPWLTSRHSFSFGDHYDPD
Mflv_0696|M.gilvum_PYR-GCK -MTRSTSVIDVRRADE----------RAKTAIEWLDSKHSFSFGSHYDPD
Mvan_0147|M.vanbaalenii_PYR-1 -MTTSPSIVNVRRADD----------RAKTRIAWLDSKHSFSFGSHYEPD
TH_0606|M.thermoresistible__bu ---MPAETMDIRWAGD----------RFATTIDWLDSRHSFSFADHYDPA
MAB_4561|M.abscessus_ATCC_1997 ------MGIDIRHADD----------RARTRISWLDSRHSFSFGEHYDPH
MSMEG_0215|M.smegmatis_MC2_155 ----MPPTVDIRRADQ----------RGVSVTDWLQSRHSFSFGDYYDPA
MUL_4766|M.ulcerans_Agy99 MPAVTADTLTLPRVRPPRPVDTERPVRSITSGPRGYEGEGFTVVRAFAGV
. : . * : . ..*:. :
Mb0187c|M.bovis_AF2122/97 NTHHGLLLVNNDDQ----MEPAS--GFDPHPHRDMEIVTWVLR------G
Rv0181c|M.tuberculosis_H37Rv NTHHGLLLVNNDDQ----MEPAS--GFDPHPHRDMEIVTWVLR------G
MMAR_0424|M.marinum_M NTHHGLLLVSNDDV----VQPRS--GFDTHPHRDMEIVTWVLE------G
MAV_5002|M.avium_104 NTHFGLLLVNNDDI----VSPGT--GFDTHPHRDMEIVTWVLA------G
Mflv_0696|M.gilvum_PYR-GCK NTHHGLLLVNNDDI----VTPGA--GFDTHPHRDMEIVTWVLR------G
Mvan_0147|M.vanbaalenii_PYR-1 NTHHGLLLVNNDDT----VKPGT--GFDTHPHRDMEIVTWVLR------G
TH_0606|M.thermoresistible__bu NTHHGVLLVNNDDR----VAPGT--GFDTHPHRDMEIVTWVLQ------G
MAB_4561|M.abscessus_ATCC_1997 NTHHGLLLVNNDDI----VLPGA--GFETHPHRDMEIITWVLH------G
MSMEG_0215|M.smegmatis_MC2_155 NTHHGLLLVNNDDI----VAAGG--GFDTHPHRDMEIVTWVLD------G
MUL_4766|M.ulcerans_Agy99 GMADLDPFVHMDQIGEVEYEPGEPRGTDWHPHRGFETVTYMIDGKLAIDG
. :* *: . * : ****.:* :*::: *
Mb0187c|M.bovis_AF2122/97 ALRHQDSAGNSGVIYPGLAQRMSAGTGILHSEMNDSATE--------PVH
Rv0181c|M.tuberculosis_H37Rv ALRHQDSAGNSGVIYPGLAQRMSAGTGILHSEMNDSATE--------PVH
MMAR_0424|M.marinum_M ELTHRDSTGNHGVIYPGLAQRMSAGSGILHSETNDSQSQ--------PVH
MAV_5002|M.avium_104 ALAHQDSTGNRGVVYPGLAQRMSAGRGILHSERNDSPSL--------PVH
Mflv_0696|M.gilvum_PYR-GCK SLVHQDSTGHSGVIYPGLAQRMSAGRGILHSEKNDSWTLTGQQSHSEPVH
Mvan_0147|M.vanbaalenii_PYR-1 SLVHQDSTGNSGVIYPGLAQRMSAGRGIMHSEKNDSWTLTGRESHSEPVH
TH_0606|M.thermoresistible__bu SLVHQDSEGNAGVIYPGLAQRMSAGSGILHSEKNDSWTLTGEQPHREPVR
MAB_4561|M.abscessus_ATCC_1997 SLVHQDSEGNAGVIYPGLAQRMSAGTGILHSEKNDSWRLSGER-HTDPVR
MSMEG_0215|M.smegmatis_MC2_155 ELAHADSMGNSGVIYPGLAQRMSAGTGVQHSEKNASSDK--------PVH
MUL_4766|M.ulcerans_Agy99 KLAHQDSHGGGGLITDGATQWMTAGSGIIHIKTPPVDTVLRGG----TFH
* * ** * *:: * :* *:** *: * : ..:
Mb0187c|M.bovis_AF2122/97 FVQMWVIP--DATGITASYQQQ-----EIDDELLRAGLVTIASGIPGQ--
Rv0181c|M.tuberculosis_H37Rv FVQMWVIP--DATGITASYQQQ-----EIDDELLRAGLVTIASGIPGQ--
MMAR_0424|M.marinum_M FVQMWVAP--DETGITPSYQQR-----EIDHRLFDGGLVTVASGIPGQ--
MAV_5002|M.avium_104 FVQMWVIP--DEAGIDPSYQQH-----EIDDTALGGGLVTIASGIRGH--
Mflv_0696|M.gilvum_PYR-GCK FVQMWVVP--DESGIQPGYQQL-----EIDDELLRGNLVTIASGMPEHSD
Mvan_0147|M.vanbaalenii_PYR-1 FVQMWVVP--DESGREPGYQQL-----EIDDELLRGNLVTIASGMPAHSD
TH_0606|M.thermoresistible__bu FIQMWVLP--DEYGVTPSYEQL-----EIEDARLRSGLIPIASGMPRYRG
MAB_4561|M.abscessus_ATCC_1997 FIQMWVTP--DDSGIDPGYQQR-----EIGNELLSGGLVTVASGMPQHRD
MSMEG_0215|M.smegmatis_MC2_155 FVQMWVIP--DRAGLTPGYEQR-----EIT---LAENLTPIASG----AG
MUL_4766|M.ulcerans_Agy99 GIQLWVNLPRKKKSTPPRYQAIEGGDVELLASADGGALVRIIAGEIDG--
:*:** . . . *: *: * : :*
Mb0187c|M.bovis_AF2122/97 DAALTLHNSSASLHGARLRPGATVSLPCAPFLH--LFVAYGRLTLEGGGE
Rv0181c|M.tuberculosis_H37Rv DAALTLHNSSASLHGARLRPGATVSLPCAPFLH--LFVAYGRLTLEGGGE
MMAR_0424|M.marinum_M DAAITLHNRHAALHCARLRPGDTIDLPSASYLH--LFVARGRLGLESFGD
MAV_5002|M.avium_104 DAAISLHNRNAALHGARLPAAAAVDLPAAPYLH--VFLARGRADIEDVGE
Mflv_0696|M.gilvum_PYR-GCK DAAITIRNRYAALHGARLEPGQSVQLPDAPYLH--LFVPRGTVTLEGAGA
Mvan_0147|M.vanbaalenii_PYR-1 AAAIAIGNRYAALHGARLQPGQSIQLPEAPYLH--LFVPRGEVSLEGAGP
TH_0606|M.thermoresistible__bu ETAITIGNRHAALHGARMAPGDSVRLPEARYLH--LFIARGAVTLEGAGA
MAB_4561|M.abscessus_ATCC_1997 QTAITIAQKNAALHAARIAAGDSVELPAAQFVH--LFVPRGAITVEAVGE
MSMEG_0215|M.smegmatis_MC2_155 DAAVTLHNRNATLYGARLRPGDAVGLPEARYVH--LFVARGRVTLEDAGD
MUL_4766|M.ulcerans_Agy99 HRGPGITHTPITLAHATVHAGAQLNIPWQRDLNSLVYVLAGRGAVGPAGH
. : : :* * : .. : :* :: ::: * : *
Mb0187c|M.bovis_AF2122/97 -LADGDAVRFTDADARGLTAN-EPSEVL-------------IWEMHAKLG
Rv0181c|M.tuberculosis_H37Rv -LADGDAVRFTDADARGLTAN-EPSEVL-------------IWEMHAKLG
MMAR_0424|M.marinum_M -VSTGDAVRFTDVEAPRLSAH-APAEVL-------------IWEMRAILG
MAV_5002|M.avium_104 -LHPGDAVRFTDTDGRRVTGL-EPSELL-------------IWEMHARLG
Mflv_0696|M.gilvum_PYR-GCK -LQEGDAVRFTATGGQRITAT-TPAEIL-------------VWEMHAGIG
Mvan_0147|M.vanbaalenii_PYR-1 -LREGDAVRFTASGGQRVTAT-APAEIL-------------VWEMHAGLG
TH_0606|M.thermoresistible__bu -LGEGDAVRFTASGGHRVTAT-GPAEIL-------------VWEMHTGLG
MAB_4561|M.abscessus_ATCC_1997 -LTEGDALRLTDIGAVRVTAI-RDAEIL-------------VWEMHTRLG
MSMEG_0215|M.smegmatis_MC2_155 -LAEGDAARLTGSGGQRVTATDEPAEIL-------------VWEMHASLA
MUL_4766|M.ulcerans_Agy99 PIHQGQLAVMGAGDRITVVADSASDKYRGTALELLILDGRPIWEPVVHYG
: *: : : . : :** . .
Mb0187c|M.bovis_AF2122/97 DSAT------------------------------------
Rv0181c|M.tuberculosis_H37Rv DSAT------------------------------------
MMAR_0424|M.marinum_M S---------------------------------------
MAV_5002|M.avium_104 G---------------------------------------
Mflv_0696|M.gilvum_PYR-GCK AA--------------------------------------
Mvan_0147|M.vanbaalenii_PYR-1 AA--------------------------------------
TH_0606|M.thermoresistible__bu G---------------------------------------
MAB_4561|M.abscessus_ATCC_1997 G---------------------------------------
MSMEG_0215|M.smegmatis_MC2_155 GD--------------------------------------
MUL_4766|M.ulcerans_Agy99 PFVMNSKAEVIEAFEDYQSGKFRSIPANALEPHRGGGTLE