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SKRWVALLVGLVLVITSCGRPLGGQAQSIYADPLRVAGMPAVDGPSGMKPGVQVPKRKIENTDNGEIDDY VKVSLADIEDFWTQFYGDSFANFRPVSRLISVDSRKNNDDLEFCRGNLTDFINAAFCPLDNSFAWDRGQL FPFLRKQMGDMAMNTVMAHEYGHSIQFHAQLINPIDDPKMSRDQVEYLMDLNQEQQADCFAGSYLRWVTQ GDSPRFTLNTADGLNKVMAAMIAIRDNDTSKKWAIHGSAFERVSAFQFGFTDGPMACKRIDSQEIIKRRG ELPRGLGVGPNGDNWPINPDTIGAVLAAASQVFPMDNPPKAVYGDGKCSDGSGTAPASYCPKDNTIALDP QALQKMAKPATDRALFSAQVNGDYSAFSVIVSRYALAAQKAAGLETEGIMTGLRTACLTGYFTSRAAGKG IVTPRAPVILSGGDLDEAVSELLSSGRASSDVNGETAPAGFSRIDAYRIGVLGNDQTCAKRFP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1466c | - | - | 100% (484) | lipoprotein peptidase LpqM |
| M. abscessus ATCC 19977 | MAB_1470c | - | e-101 | 43.20% (493) | lipoprotein peptidase LpqM |
| M. abscessus ATCC 19977 | MAB_2867 | - | 3e-05 | 23.38% (231) | hypothetical protein MAB_2867 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0427 | lpqM | 3e-95 | 41.25% (480) | lipoprotein peptidase LpqM |
| M. gilvum PYR-GCK | Mflv_2346 | - | 1e-104 | 44.08% (490) | LpqM |
| M. tuberculosis H37Rv | Rv0419 | lpqM | 2e-95 | 41.25% (480) | lipoprotein peptidase LpqM |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0728 | lpqM | 9e-97 | 41.13% (479) | lipoprotein peptidase LpqM |
| M. avium 104 | MAV_4736 | - | 8e-98 | 41.25% (480) | LpqM protein |
| M. smegmatis MC2 155 | MSMEG_4913 | - | 1e-110 | 45.02% (482) | LpqM protein |
| M. thermoresistible (build 8) | TH_1205 | - | 1e-105 | 44.99% (489) | LpqM protein |
| M. ulcerans Agy99 | MUL_3589 | lpqM | 2e-95 | 40.71% (479) | lipoprotein peptidase LpqM |
| M. vanbaalenii PYR-1 | Mvan_4299 | - | 1e-106 | 44.90% (490) | LpqM |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2346|M.gilvum_PYR-GCK --------MSPSRSSKPSRFRSSAALLAGTAVLAGAA-CSTMLQGNAVSV
Mvan_4299|M.vanbaalenii_PYR-1 --------MSPSRRPG-TRIGVAAAVCA---VLAATA-CSTTLQGNAVSV
MSMEG_4913|M.smegmatis_MC2_155 --------MS--------RRHLLGAVIATCVVVPLAA-CSTIVEGSAVSV
TH_1205|M.thermoresistible__bu --------MTRRRR--LAAFSTTPALLAVLVVVLLVSGCARVVRGSAVSV
Mb0427|M.bovis_AF2122/97 MHGRGRYRPLVRCVRPRRVAASVRTPIACLAAVVVIAGCTTVVDGRALSI
Rv0419|M.tuberculosis_H37Rv MHGRGRYRPLVRCVRPRRVAASVRTPIACLAAVVVIAGCTTVVDGRALSI
MMAR_0728|M.marinum_M MDNRGRKWLGVRRSRHGGLIASLWAATAFLTALLVVAGCTTIVDGRALSI
MUL_3589|M.ulcerans_Agy99 MDNRGRKWLGVRRSRHSGLIASLWAATAFLTALLVVAGCTTIADGRALSI
MAV_4736|M.avium_104 ---------------------------MSAAAVLLVAGCSTFVEGRALSM
MAB_1466c|M.abscessus_ATCC_199 --------------------MSKRWVALLVGLVLVITSCGRPLGGQAQSI
: : * * * *:
Mflv_2346|M.gilvum_PYR-GCK FDDPFKVAGMPATDGPTGLRPDAESPARDVTGTDGGDIDNLAASAVSDIE
Mvan_4299|M.vanbaalenii_PYR-1 FDDPFRVAGMPATDGPTGVRPNAEPPARDVEGTDGGAIDELAASAISDIE
MSMEG_4913|M.smegmatis_MC2_155 FADPFSVAGMPATDGPSGLRPDAAAPTREVTDSDGGKIDELAASAVSDIE
TH_1205|M.thermoresistible__bu FADPFRVAGMPAVDGPSGLRPDADAPTRTVRATDGGPIDQLAASAVSDVE
Mb0427|M.bovis_AF2122/97 LNDPFRVGGLPATNGPSGARPDAPAASGTVINTNNGAIDKLSLLSVNDIE
Rv0419|M.tuberculosis_H37Rv LNDPFRVGGLPATNGPSGARPDAPAASGTVINTNNGAIDKLSLLSVNDIE
MMAR_0728|M.marinum_M LNDPFRVGGLPATNGPSGPRPDGPPPTGTVINTNNGPIDKLSLLSVNDIQ
MUL_3589|M.ulcerans_Agy99 LNDPFRVGGLPATNGPSGPRPDGPPPTGTVINTNNGPIDKLSLLSVNDIQ
MAV_4736|M.avium_104 LNDPFLVGGLPATNGPSGIRSNAPAPTGKVLNTDNGSIDSLSLLSINDIE
MAB_1466c|M.abscessus_ATCC_199 YADPLRVAGMPAVDGPSGMKPGVQVPKRKIENTDNGEIDDYVKVSLADIE
**: *.*:**.:**:* :.. . : ::.* **. :: *::
Mflv_2346|M.gilvum_PYR-GCK DYWATAYEDAFDERFKPVAELISWDA-NGFDG-EFCGDTTYGLVNAGYCY
Mvan_4299|M.vanbaalenii_PYR-1 DYWAVAYEETFDEKFRPVAELISWDA-NGFDG-EFCGEDTYGLINAGYCY
MSMEG_4913|M.smegmatis_MC2_155 EFWSATYGEVFEGDFTPVRELISWDS-ESFDG-EFCGLNTFALVNAAYCK
TH_1205|M.thermoresistible__bu DYWDTAYLDTFGERFTPVRGLVSWDA-AELFE-VFCSMDTHGLENAAFCF
Mb0427|M.bovis_AF2122/97 DYWMAVYSESLKGTFRPVGKLVSYDS-NDPSSPIVCHIDTYQLVNAFFSS
Rv0419|M.tuberculosis_H37Rv DYWMAVYSESLKGTFRPVGKLVSYDS-NDPSSPIVCHIDTYQLVNAFFSS
MMAR_0728|M.marinum_M DYWKANY-EPLQGTFRPVSKLVSYDS-NDPNSPIVCHNDTYELVNAFFTS
MUL_3589|M.ulcerans_Agy99 DYWKANY-EPLQGTFRPVSKLVSYDS-NDPNSPIVCHNDTYELVNAFFTS
MAV_4736|M.avium_104 DYWRSVYGQSLKGKFVPISKIVSYNS-TDPSSPIVCHNDTYQLVNAFYTS
MAB_1466c|M.abscessus_ATCC_199 DFWTQFYGDSFAN-FRPVSRLISVDSRKNNDDLEFCRGNLTDFINAAFCP
::* * : : * *: ::* :: .* : ** :
Mflv_2346|M.gilvum_PYR-GCK ADRTIGWDRGELLPSLQRAHGDIGVVMVLAHEYGHAVSRLSGLSG-RDTP
Mvan_4299|M.vanbaalenii_PYR-1 PDRTIGWDRGELLPGLQRAHGDMGVVMVLAHEYGHAISRLAGLTK-KDTP
MSMEG_4913|M.smegmatis_MC2_155 PDRTIGWDRGVLLPSLRKQNGDMGVVMVLAHEYGHAIQQQAKLVR-RNTP
TH_1205|M.thermoresistible__bu PERTIGWDRGQMLPRLRRANGDMAVVMVLAHEYGHWVSRQAGLTS-RRSP
Mb0427|M.bovis_AF2122/97 RCNLIAWDRGVFMAVAQEYFGDMSVNGVLAHEFGHALQVMANLVT-RKDP
Rv0419|M.tuberculosis_H37Rv RCNLIAWDRGVFMAVAQEYFGDMSVNGVLAHEFGHALQVMANLVT-RKDP
MMAR_0728|M.marinum_M RCNMIAWDRGVFMPVAQEYFGEISVTGVLAHEFGHALQVMAKLVT-RRDP
MUL_3589|M.ulcerans_Agy99 RCNMIAWDRGVFMPVAQEYFGEISVTGVLAHEFGHALQVMAKLVT-RRDP
MAV_4736|M.avium_104 RCNLIAWDRGVFMPVAQKYFGDMSVTGVLAHEFGHALQQMAALVT-KRDA
MAB_1466c|M.abscessus_ATCC_199 LDNSFAWDRGQLFPFLRKQMGDMAMNTVMAHEYGHSIQFHAQLINPIDDP
. :.**** ::. :. *::.: *:***:** :. : * .
Mflv_2346|M.gilvum_PYR-GCK TLVA-----------EQQADCFSGAYMRWVAEDSSQRFSLSTGEGLNNVL
Mvan_4299|M.vanbaalenii_PYR-1 TLVA-----------EQQADCFGGAYMRWVAEDSSARFTLSTGEGLNNVL
MSMEG_4913|M.smegmatis_MC2_155 TLVS-----------EQQADCLAGTYMRWVAEGNSPRFTLGTGDGLNSLL
TH_1205|M.thermoresistible__bu ILVA-----------EQQADCFAGTYLRWVAEGNSRRFTLSTADGLNDVL
Mb0427|M.bovis_AF2122/97 TIVR-----------EQQADCFAGVYLWWVAEGKSTRFTLSTADGLDHVL
Rv0419|M.tuberculosis_H37Rv TIVR-----------EQQADCFAGVYLWWVAEGKSTRFTLSTADGLDHVL
MMAR_0728|M.marinum_M TIVR-----------EQQADCFAGVYLYWVAEGKSPRFRLSTADGLDHVL
MUL_3589|M.ulcerans_Agy99 TIVR-----------EQQADCFAGVYLYWVAEGKSPRFRLSTADGLDHVF
MAV_4736|M.avium_104 TIVR-----------EQQADCFAGVYLFWVADGKSPRFTLSTADGLDHVL
MAB_1466c|M.abscessus_ATCC_199 KMSRDQVEYLMDLNQEQQADCFAGSYLRWVTQGDSPRFTLNTADGLNKVM
: ******:.* *: **::..* ** *.*.:**: ::
Mflv_2346|M.gilvum_PYR-GCK AGVISFRDPLLNEGDPDAGYDEHGSAFERVSAFQFGFTDGPSACSGIDLD
Mvan_4299|M.vanbaalenii_PYR-1 AGVISFRDPLLAENDPDVGFDEHGTAFERLSAFQFGFTDGPSACAAIDPA
MSMEG_4913|M.smegmatis_MC2_155 AAVIAFRDPLLTESDMYLGVDEHGSAFERVSAFQFGFTDGAAACKAIDVK
TH_1205|M.thermoresistible__bu AAVVAVRDPVLTEGDWRAGLNEHGSAFERLSAFQFGFTNGPSACAAIDMP
Mb0427|M.bovis_AF2122/97 AGIITTRDPVMEADAEND--DEHGSALDRVSAFQLGFINGTPACAAIDED
Rv0419|M.tuberculosis_H37Rv AGIITTRDPVMEADAEND--DEHGSALDRVSAFQLGFINGTPACAAIDED
MMAR_0728|M.marinum_M AGIITTRDPVMDTDEQND--DEHGSALDRVSAFQMGFLSGTPACAAINES
MUL_3589|M.ulcerans_Agy99 AGIITTRDPVMDTDEQND--DEHGSALDRVSAFQMGLLSGTPACAAINES
MAV_4736|M.avium_104 AGIITTRDPVMDSETAND--DAHGSALDRISAFQMGFLNGASACASINRK
MAB_1466c|M.abscessus_ATCC_199 AAMIAIRD-----NDTSKKWAIHGSAFERVSAFQFGFTDGPMACKRIDSQ
*.::: ** **:*::*:****:*: .*. ** *:
Mflv_2346|M.gilvum_PYR-GCK EIGQRRGDLPVLLPED-----QTGELPVTEDSARSIVDAMEILFEPQNPP
Mvan_4299|M.vanbaalenii_PYR-1 EIDQRRGELPVLLPED-----QTGELPVTEDSTRSIIDAMGILFSPKNPP
MSMEG_4913|M.smegmatis_MC2_155 EISQRRGDLPVLLPED-----QTGELPITEESVRAMVDALNVVFKPKNPP
TH_1205|M.thermoresistible__bu EIKQRRGELPVLLPEN-----QTGELPVTERSVRTLLDALTIVFRPAAPP
Mb0427|M.bovis_AF2122/97 EVERRRGDLPTTLRVDASGNPETGEVGINEETLSTLMELMGKIFSPKNPP
Rv0419|M.tuberculosis_H37Rv EVERRRGDLPTALRVDASGNPETGEVGINEETLSTLMELMGKIFSPKNPP
MMAR_0728|M.marinum_M EIVRRRGDLPTGLRVDSSGNPETGEVPINQDTLTTLMELLGKIFSPTDPP
MUL_3589|M.ulcerans_Agy99 EIVRRRGDLPTGLRVDSSGNSETGEVPINQDTLTTLMELLGKIFSPTDPP
MAV_4736|M.avium_104 EIEQRRGDLPYALRVDTSGRPETGEVPINQDTLSTLMELLGKIFAPANPP
MAB_1466c|M.abscessus_ATCC_199 EIIKRRGELPRGLGVG----PNGDNWPINPDTIGAVLAAASQVFPMDNPP
*: :***:** * . : .: :. : ::: :* **
Mflv_2346|M.gilvum_PYR-GCK ALSFEPADADNCADARPSPPASFCPATNTIVVDLPALEEMGTQADP-DDG
Mvan_4299|M.vanbaalenii_PYR-1 ALSFDADEAESCADARPSPPASFCPATNTIVVDLPALEEMGAQADP-QDG
MSMEG_4913|M.smegmatis_MC2_155 RLSFAARDADDCPDARPSPPTSYCPATNTIVVDLDELETVGFKPVD-GQV
TH_1205|M.thermoresistible__bu RLTLAAAEAESCPDARPSPPASYCPATNVIAVDLDGLAALGAQSDT-TDG
Mb0427|M.bovis_AF2122/97 TLSYQPAG---CPDAKPSPPAAYCPATNTIVVDLPALARMGKVAS--AAE
Rv0419|M.tuberculosis_H37Rv TLSYQPAG---CPDAKPSPPAAYCPATNTIVVDLPALARMGKVAS--AAE
MMAR_0728|M.marinum_M TLSYQQAG---CPDAKPSPPASYCPATNTITVDLPALAAIGKVAD--SKQ
MUL_3589|M.ulcerans_Agy99 TLSYQQAG---CPDAKPSPPASYCPATNTITVDLPALAAIGKVAD--SKQ
MAV_4736|M.avium_104 ALSYQPAT---CPDAKPSPPASYCPATNTIAVDLPKLAALGRVAD--ENE
MAB_1466c|M.abscessus_ATCC_199 KAVYGDGK---CSDGSGTAPASYCPKDNTIALDPQALQKMAKPATDRALF
*.*. :.*:::** *.*.:* * :. .
Mflv_2346|M.gilvum_PYR-GCK TALAAGDNTAYSVLVSRYMLAIQHERGGVALNSAEAALRTACLTGVATVK
Mvan_4299|M.vanbaalenii_PYR-1 GSLATGDNMAYSVLVSRYMLAIQQEHGGAALDTAEAALRTACLTGVATVK
MSMEG_4913|M.smegmatis_MC2_155 GALALGDNSAYSLLISRYMVARQHERG-LVLDNAQAALRTACLTGVATAK
TH_1205|M.thermoresistible__bu --LASGDNTAYSVLASRFVLALQREHGGVALNDAKAALRTACLTGVATTK
Mb0427|M.bovis_AF2122/97 HSLPQGDDTSLSIVMSRYALAVQHERG-LPMQSPWTALRTACLTGVAHRK
Rv0419|M.tuberculosis_H37Rv HSLPQGDDTSLSIVMSRYALAVQHERG-LPMQSPWTALRTACLTGVAHRK
MMAR_0728|M.marinum_M HSLPQGDDTALSIVMSRYALSVQHQRD-LPMQSPWTALRTACLTGVVHRE
MUL_3589|M.ulcerans_Agy99 HSLPQGDDTALSIVMSRYALSVQHQRD-LPMQSPWTALRTACLTGVVHRE
MAV_4736|M.avium_104 HTLPQGDDTALSVVMSRYALAVQHERG-LAMQSPWTALRTACLTGVVHRR
MAB_1466c|M.abscessus_ATCC_199 SAQVNGDYSAFSVIVSRYALAAQKAAG-LETEGIMTGLRTACLTGYFTSR
** : *:: **: :: *: . : :.******** .
Mflv_2346|M.gilvum_PYR-GCK MSEEVTTPDGDTIALTAGDVDEAVSGMLTNGLAASDVNGESVPSGFSRID
Mvan_4299|M.vanbaalenii_PYR-1 MTEDVTTPDGDTIALTAGDIDEAVSGILTNGLVASDVNGASVPSGFSRID
MSMEG_4913|M.smegmatis_MC2_155 LSQPVTTPDGNTIVLTAGDVDEAVSGILTTGLVAGDVNGDSVPSGFSRID
TH_1205|M.thermoresistible__bu LSAGVVTSDGTSISLTAGDLDEAVSGMLTNGLVASDVHGETVPSGFSRID
Mb0427|M.bovis_AF2122/97 MAVPIDLPSGQQLVLTAGDLDEAVSGLLTNRMVASDADGVSVPAGFTRIA
Rv0419|M.tuberculosis_H37Rv MAVPIDLPSGQQLVLTAGDLDEAVSGLLTNRMVASDADGVSVPAGFTRIA
MMAR_0728|M.marinum_M MAEPIELPSGQQLVLTAGDLDEAVSGLLTNRMVASDADGISVPAGFTRIA
MUL_3589|M.ulcerans_Agy99 MAEPIELPSGQQLVLTAGDLDEAVSGLLTNRMVASDADGISVPAGFTRIA
MAV_4736|M.avium_104 MAEPIELPSHNQLLLTAGDLDEAVAGLLTNHLVASDADGTSVPAGFTRIA
MAB_1466c|M.abscessus_ATCC_199 AAGKGIVTPRAPVILSGGDLDEAVSELLSSGRASSDVNGETAPAGFSRID
: . : *:.**:****: :*:. .:.*..* :.*:**:**
Mflv_2346|M.gilvum_PYR-GCK AFRVGVLGDADRCFTRFP-
Mvan_4299|M.vanbaalenii_PYR-1 AFRLGVLSDTERCFKRFP-
MSMEG_4913|M.smegmatis_MC2_155 AFRVGILGDEARCLKRFS-
TH_1205|M.thermoresistible__bu AYRLGVLGDASRCYQRFG-
Mb0427|M.bovis_AF2122/97 AFRAGVGGDMDACYARYPG
Rv0419|M.tuberculosis_H37Rv AFRAGVGGDMDACYARYPG
MMAR_0728|M.marinum_M AFRAGVSGDMEACYSRYPG
MUL_3589|M.ulcerans_Agy99 TFRAGVSGDMEACYSRYPG
MAV_4736|M.avium_104 AFRGGVTGNADACYSRYPG
MAB_1466c|M.abscessus_ATCC_199 AYRIGVLGNDQTCAKRFP-
::* *: .: * *: