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VKILALGGAGAMGAAAVRAALDIPGVEEIVVADQDLGAAEALVRRLGEGPVPTRAMCVDVTDAGALRTAL EDVDLVLNTVGPYFRFGLTVLRMAIETRTHYLDICDDWEPTLQMLGLDEIARAHGVCAVIGMGASPGISN LLAATAAAELDEVDDVYTAWPVDVGGSGADTEEKSQLLGADGRPTAAATHWMEQASGTITAVGAGRLVEK RPLSPVSLELPAGRRGTAYSIGHPEPITVQRTLKPRGDALNLMVIKPWTVAYLDTLRRDMDAGRLSREEA AEAFAVPKFRRVLRSAYVALRLRGPGTLPPFFAAVTGERHENRYTVLARLNLEGSQSHPIRTALRDMARI TGVPLALGMAQVIDGSGRRPGVHPPEAVIEPARFFADLAVALGCDSGVSPYLVEQQPLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0919 | - | - | 100% (409) | hypothetical protein MAB_0919 |
| M. abscessus ATCC 19977 | MAB_3325c | - | 2e-10 | 32.53% (166) | saccharopine dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0521 | hemA | 7e-05 | 37.84% (74) | glutamyl-tRNA reductase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0509 | hemA | 7e-05 | 37.84% (74) | glutamyl-tRNA reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3555 | - | 2e-07 | 27.06% (170) | saccharopine dehydrogenase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6311 | lys1 | 9e-07 | 27.91% (172) | saccharopine dehydrogenase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2788 | - | 1e-07 | 27.06% (170) | saccharopine dehydrogenase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3555|M.marinum_M MRILLVGAGGVGSAFCAIAARRS-----------------FFEHVVVCDY
MUL_2788|M.ulcerans_Agy99 MRILLVGAGGVGSAFCAIAARRS-----------------FFEHVVVCDY
MSMEG_6311|M.smegmatis_MC2_155 MRILLVGAGGVGSAFCAIAARRN-----------------FFDQIVVCDY
Mb0521|M.bovis_AF2122/97 MSVLLFGVSHRSAPVVVLEQLSIDESDQVKIIDRVLASPLVTEAMVLSTC
Rv0509|M.tuberculosis_H37Rv MSVLLFGVSHRSAPVVVLEQLSIDESDQVKIIDRVLASPLVTEAMVLSTC
MAB_0919|M.abscessus_ATCC_1997 MKILALGGAGAMGAAAVRAALDIPG----------------VEEIVVADQ
* :* .* . .. . : :*:.
MMAR_3555|M.marinum_M DEARASRAAQAVADAR-FCSAALDAGSADAVAAAVRRHQITHVVNAVDPR
MUL_2788|M.ulcerans_Agy99 DEARASRAAQAVADAR-FCSAALDAGCADAVAAAVRRHQITHVVNAVDPR
MSMEG_6311|M.smegmatis_MC2_155 DESRARQAAEAVGDAR-FTSAQVDATSADAVADLVREHQITHVMNAVDPR
Mb0521|M.bovis_AF2122/97 NRVEVYAVVDAFHGGLSVIGQVLAEHSGMSMGELTKYAYVRYSEAAVEHL
Rv0509|M.tuberculosis_H37Rv NRVEVYAVVDAFHGGLSVIGQVLAEHSGMSMGELTKYAYVRYSEAAVEHL
MAB_0919|M.abscessus_ATCC_1997 DLGAAEALVRRLGEGP-VPTRAMCVDVTDAGALRTALEDVDLVLNTVGPY
: . . . . . : : . . : :*
MMAR_3555|M.marinum_M FVMP------IFEGALAAGADYLDMAMSLSQRHP-EQPYQLTGVKLGDEQ
MUL_2788|M.ulcerans_Agy99 FVMP------IFEGALAAGADYLDMAISLSERHP-EQPYQLTGVKLGDEQ
MSMEG_6311|M.smegmatis_MC2_155 FVMP------IFNGALAGGADYLDMAMSLSRRHP-DRPYELTGVKLGDEQ
Mb0521|M.bovis_AF2122/97 FAVASGLDSAVIGEQQVLGQVRRAYAVAESNRTVGRVLHELAQRALSVGK
Rv0509|M.tuberculosis_H37Rv FAVASGLDSAVIGEQQVLGQVRRAYAVAESNRTVGRVLHELAQRALSVGK
MAB_0919|M.abscessus_ATCC_1997 FRFG-------LTVLRMAIETRTHYLDICDDWEPTLQMLGLDEIARAHGV
* . : . * .
MMAR_3555|M.marinum_M FAADDQWRAADRLALVGMGVEPGLSDVFARYAADHLFTDIDELGTRDGAN
MUL_2788|M.ulcerans_Agy99 FAADDQWRAADRLALVGMGVEPGLSDVFARYAADHLFTDIDELGTRDGAN
MSMEG_6311|M.smegmatis_MC2_155 FGAAEDWEAAGRLALVGIGVEPGLSDVFARYAADHLFSEIDELGTRDGSS
Mb0521|M.bovis_AF2122/97 RVHSETAIDAAGASVVSVALGMAERKLGSLAGTTAVVIGAGAMGALSAVH
Rv0509|M.tuberculosis_H37Rv RVHSETAIDAAGASVVSVALGMAERKLGSLAGTTAVVIGAGAMGALSAVH
MAB_0919|M.abscessus_ATCC_1997 CAVIGMGASPGISNLLAATAAAELDEVDDVYTAWPVDVGGSGADTEEKSQ
. ::. .: : : . .: .
MMAR_3555|M.marinum_M LTVDGYDFAPSFS--------IWTTIEECLNPPVIWEHDRGWFVTEPFSE
MUL_2788|M.ulcerans_Agy99 LTVDGYDFAPSFS--------IWTTIEECLNPPVIWEHDRGWFVTEPFSE
MSMEG_6311|M.smegmatis_MC2_155 LVVEGCDFAPSFS--------IWTTIEECLNPPVVWEADRGWFVTEPFSE
Mb0521|M.bovis_AF2122/97 LTRAGVGHIQVLNRSLSRAQRLARRIRESGVPAEALALDR---LANVLAD
Rv0509|M.tuberculosis_H37Rv LTRAGVGHIQVLNRSLSRAQRLARRIRESGVPAEALALDR---LANVLAD
MAB_0919|M.abscessus_ATCC_1997 LLGADGRPTAAAT----------HWMEQASGTITAVGAGR--LVEKRPLS
* . . :.:. . .* : : .
MMAR_3555|M.marinum_M PEVFDFPDGIGPVECVNVEHEEVLLMPRWVKAKRATFKYGLGTEFIEVLK
MUL_2788|M.ulcerans_Agy99 PEVFDFPDGIGPVECVNVEHEEVLLMPRWVKAKRATFKYGLGTEFIEVLK
MSMEG_6311|M.smegmatis_MC2_155 PEVFDFPEGIGPVECVNVEHEEVLLMPRWVKCKRATFKYGLGSEFIDVLK
Mb0521|M.bovis_AF2122/97 ADVVVSCTGAVRPVVSLADVHHALAAARRDEATRPLVICDLG-MPRDVDP
Rv0509|M.tuberculosis_H37Rv ADVVVSCTGAVRPVVSLADVHHALAAARRDEATRPLVICDLG-MPRDVDP
MAB_0919|M.abscessus_ATCC_1997 PVSLELPAGRRGTAYSIGHPEPITVQRTLKPRGDALNLMVIKPWTVAYLD
. . * . . . :
MMAR_3555|M.marinum_M TLRKLGLDRTEKITVGG----VQVSPRDVVAACLPDPATLGPKMHG-KTC
MUL_2788|M.ulcerans_Agy99 TLRKLGLDRTEKITVGG----VQVSPRDVVAACLPDPATLGPKMHG-KTC
MSMEG_6311|M.smegmatis_MC2_155 TLHKLGLDRTDKVRVPGANGPVEVSPRDVVAACLPNPATLGPQMHG-KTC
Mb0521|M.bovis_AF2122/97 AVARLPCVWVVDVDSVQHEPSAHAAAADVEAARHIVAAEVASYLVG-QRM
Rv0509|M.tuberculosis_H37Rv AVARLPCVWVVDVDSVQHEPSAHAAAADVEAARHIVAAEVASYLVG-QRM
MAB_0919|M.abscessus_ATCC_1997 TLRRD--MDAGRLSREE----AAEAFAVPKFRRVLRSAYVALRLRGPGTL
:: : . : . : .* :. : *
MMAR_3555|M.marinum_M AGLWVTGTGKDGNPRSTYLYHVVDNQWSMNEYG----------HQCVVWQ
MUL_2788|M.ulcerans_Agy99 AGLWVTGTGKDGNPRSTYLYHVVDNQWSMNEYG----------HQCVVWQ
MSMEG_6311|M.smegmatis_MC2_155 AGLWVTGKGKDGAPRSTYLYHVVDNQWSMAEYG----------HQCVVWQ
Mb0521|M.bovis_AF2122/97 AEVTPTVTALRQRAAEVVEAELLRLDNRLPGLQSVQREEVARTVRRVVDK
Rv0509|M.tuberculosis_H37Rv AEVTPTVTALRQRAAEVVEAELLRLDNRLPGLQSVQREEVARTVRRVVDK
MAB_0919|M.abscessus_ATCC_1997 PPFFAAVTGERHENRYTVLARLNLEGSQSHPIR--------TALRDMARI
. . : .. . .: : :.
MMAR_3555|M.marinum_M TAINPVVALELLASG--------TWSGRGVLGPEAFDAVPFLELLSAYGA
MUL_2788|M.ulcerans_Agy99 TAINPVVALELLASG--------TWSGRGVLGPEAFDAVPFLELLSAYGA
MSMEG_6311|M.smegmatis_MC2_155 TAINPVVALELLASG--------MWSGAGVLGPEAFDAVPFLNLLKDYGS
Mb0521|M.bovis_AF2122/97 LLHAPTVRIKQLASAPGGDSYAEALRELFELDQTAVDAVATAGELPVVPS
Rv0509|M.tuberculosis_H37Rv LLHAPTVRIKQLASAPGGDSYAEALRELFELDQTAVDAVATAGELPVVPS
MAB_0919|M.abscessus_ATCC_1997 TGVPLALGMAQVIDG--------SGRRPGVHPPEAVIEPARFFADLAVAL
.: : : .. *. .
MMAR_3555|M.marinum_M PWGLQEVPARS------------
MUL_2788|M.ulcerans_Agy99 PWGLQEVPARS------------
MSMEG_6311|M.smegmatis_MC2_155 PWGIKEL----------------
Mb0521|M.bovis_AF2122/97 GFDAESRRGGGDMQSSPKRSPSN
Rv0509|M.tuberculosis_H37Rv GFDAESRRGGGDMQSSPKRSPSN
MAB_0919|M.abscessus_ATCC_1997 GCDSGVSPYLVEQQPLP------
.