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M. smegmatis MC2 155 MSMEG_6311 (lys1)

RILLVGAGGVGSAFCAIAARRNFFDQIVVCDYDESRARQAAEAVGDARFTSAQVDATSADAVADLVREHQ
ITHVMNAVDPRFVMPIFNGALAGGADYLDMAMSLSRRHPDRPYELTGVKLGDEQFGAAEDWEAAGRLALV
GIGVEPGLSDVFARYAADHLFSEIDELGTRDGSSLVVEGCDFAPSFSIWTTIEECLNPPVVWEADRGWFV
TEPFSEPEVFDFPEGIGPVECVNVEHEEVLLMPRWVKCKRATFKYGLGSEFIDVLKTLHKLGLDRTDKVR
VPGANGPVEVSPRDVVAACLPNPATLGPQMHGKTCAGLWVTGKGKDGAPRSTYLYHVVDNQWSMAEYGHQ
CVVWQTAINPVVALELLASGMWSGAGVLGPEAFDAVPFLNLLKDYGSPWGIKEL*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_6311	lys1	-	100% (405)	saccharopine dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_3325c	-	1e-176	72.28% (404)	saccharopine dehydrogenase
M. marinum M	MMAR_3555	-	0.0	83.46% (405)	saccharopine dehydrogenase
M. avium 104	-	-	-	-	-
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	MUL_2788	-	0.0	82.96% (405)	saccharopine dehydrogenase
M. vanbaalenii PYR-1	-	-	-	-	-

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3555|M.marinum_M               MRILLVGAGGVGSAFCAIAARRSFFEHVVVCDYDEARASRAAQAVADARF
MUL_2788|M.ulcerans_Agy99           MRILLVGAGGVGSAFCAIAARRSFFEHVVVCDYDEARASRAAQAVADARF
MSMEG_6311|M.smegmatis_MC2_155      MRILLVGAGGVGSAFCAIAARRNFFDQIVVCDYDESRARQAAEAVGDARF
MAB_3325c|M.abscessus_ATCC_199      MRILIVGAGGVGSAAAFIAARRDFFEALVIADYDIARAQAVVDRLGDSRF
                                    ****:********* . *****.**: :*:.*** :**  ..: :.*:**

MMAR_3555|M.marinum_M               CSAALDAGSADAVAAAVRRHQITHVVNAVDPRFVMPIFEGALAAGADYLD
MUL_2788|M.ulcerans_Agy99           CSAALDAGCADAVAAAVRRHQITHVVNAVDPRFVMPIFEGALAAGADYLD
MSMEG_6311|M.smegmatis_MC2_155      TSAQVDATSADAVADLVREHQITHVMNAVDPRFVMPIFNGALAGGADYLD
MAB_3325c|M.abscessus_ATCC_199      MAARIDASCADDVTALCREHRITHALNAVDPRFVMSVFDGCFAAGVTYLD
                                     :* :** .** *:   *.*:***.:*********.:*:*.:*.*. ***

MMAR_3555|M.marinum_M               MAMSLSQRHPEQPYQLTGVKLGDEQFAADDQWRAADRLALVGMGVEPGLS
MUL_2788|M.ulcerans_Agy99           MAISLSERHPEQPYQLTGVKLGDEQFAADDQWRAADRLALVGMGVEPGLS
MSMEG_6311|M.smegmatis_MC2_155      MAMSLSRRHPDRPYELTGVKLGDEQFGAAEDWEAAGRLALVGIGVEPGLS
MAB_3325c|M.abscessus_ATCC_199      MAMSLSHRHPDKPYELPGVMLGDEQFAATEKWKAAGLLALVGIGVEPGLS
                                    **:***.***::**:*.** ******.* :.*.**. *****:*******

MMAR_3555|M.marinum_M               DVFARYAADHLFTDIDELGTRDGANLTVDGYDFAPSFSIWTTIEECLNPP
MUL_2788|M.ulcerans_Agy99           DVFARYAADHLFTDIDELGTRDGANLTVDGYDFAPSFSIWTTIEECLNPP
MSMEG_6311|M.smegmatis_MC2_155      DVFARYAADHLFSEIDELGTRDGSSLVVEGCDFAPSFSIWTTIEECLNPP
MAB_3325c|M.abscessus_ATCC_199      DVFARYAADHLFSEIDELGTRDGSNLEVRGYRFAPSFSIWTTIEECLNPP
                                    ************::*********:.* * *  ******************

MMAR_3555|M.marinum_M               VIWEHDRGWFVTEPFSEPEVFDFPDGIGPVECVNVEHEEVLLMPRWVKAK
MUL_2788|M.ulcerans_Agy99           VIWEHDRGWFVTEPFSEPEVFDFPDGIGPVECVNVEHEEVLLMPRWVKAK
MSMEG_6311|M.smegmatis_MC2_155      VVWEADRGWFVTEPFSEPEVFDFPEGIGPVECVNVEHEEVLLMPRWVKCK
MAB_3325c|M.abscessus_ATCC_199      LIWERGKGFFTTEPFSEPEVFDFPGGIGPVECVNVEHEEVVLMPRWVNAR
                                    ::** .:*:*.************* ***************:******:.:

MMAR_3555|M.marinum_M               RATFKYGLGTEFIEVLKTLRKLGLDRTEKITVGG----VQVSPRDVVAAC
MUL_2788|M.ulcerans_Agy99           RATFKYGLGTEFIEVLKTLRKLGLDRTEKITVGG----VQVSPRDVVAAC
MSMEG_6311|M.smegmatis_MC2_155      RATFKYGLGSEFIDVLKTLHKLGLDRTDKVRVPGANGPVEVSPRDVVAAC
MAB_3325c|M.abscessus_ATCC_199      RVTFKYGLGAEFINVLRTLHLVGLDSTAPVSVHANGGTAAVSPRDVVAAC
                                    *.*******:***:**:**: :*** *  : * .    . **********

MMAR_3555|M.marinum_M               LPDPATLGPKMHGKTCAGLWVTGTGKDGNPRSTYLYHVVDNQWSMNEYGH
MUL_2788|M.ulcerans_Agy99           LPDPATLGPKMHGKTCAGLWVTGTGKDGNPRSTYLYHVVDNQWSMNEYGH
MSMEG_6311|M.smegmatis_MC2_155      LPNPATLGPQMHGKTCAGLWVTGKGKDGAPRSTYLYHVVDNQWSMAEYGH
MAB_3325c|M.abscessus_ATCC_199      LPDPAGLGHLMRGATCAGLWVTGTGKDGRPREVYLHHVVDNEWTMARDGA
                                    **:** **  *:* *********.**** **..**:*****:*:* . * 

MMAR_3555|M.marinum_M               QCVVWQTAINPVVALELLASGTWSGRGVLGPEAFDAVPFLELLSAYGAPW
MUL_2788|M.ulcerans_Agy99           QCVVWQTAINPVVALELLASGTWSGRGVLGPEAFDAVPFLELLSAYGAPW
MSMEG_6311|M.smegmatis_MC2_155      QCVVWQTAINPVVALELLASGMWSGAGVLGPEAFDAVPFLNLLKDYGSPW
MAB_3325c|M.abscessus_ATCC_199      QCVVWQTAVNPVVALELLAEGVWSGAGVLGPEAFDSLPFLDRLNTFGAPW
                                    ********:**********.* *** *********::***: *. :*:**

MMAR_3555|M.marinum_M               GLQEVPARS
MUL_2788|M.ulcerans_Agy99           GLQEVPARS
MSMEG_6311|M.smegmatis_MC2_155      GIKEL----
MAB_3325c|M.abscessus_ATCC_199      GIQERAVAA
                                    *::*