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TYPPQEPPTSGDPSAYDPNQPPPGYPNQPPPGYQPPPPGYQPGYQAGPPPGGPQYQGAQFPPPGYPPAGY GYPQQRPWPPQGPFSAGESWSWSWAQVSKRFGTFIPPYLVWFLAIGLPVGIVYAILMASLPQTSTSGYGG NSRSSYSYSYEGPELSGGAIAIMILLYAVVFAVSLYVGACLISANLDVADGKPVSFGTFFRARGFGLYVG AALLVGVGVLIGSLLIIGGVIFGFFAQYAVFFAIDRGLGPVDALKASFQLVKDNLGQALVVFLITLGVAF GGFALTFITCGLGGIIAYPAAGALTGLIHVYTYRRLTGGTIAPAPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0651c | - | - | 100% (327) | hypothetical protein MAB_0651c |
| M. abscessus ATCC 19977 | MAB_1370c | - | 4e-11 | 31.28% (195) | hypothetical protein MAB_1370c |
| M. abscessus ATCC 19977 | MAB_0392c | - | 4e-09 | 23.99% (321) | hypothetical protein MAB_0392c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2590 | - | 2e-53 | 38.07% (331) | hypothetical protein Mb2590 |
| M. gilvum PYR-GCK | Mflv_2044 | - | 3e-44 | 37.95% (332) | integral membrane protein-like protein |
| M. tuberculosis H37Rv | Rv2560 | - | 1e-53 | 38.07% (331) | hypothetical protein Rv2560 |
| M. leprae Br4923 | MLBr_00222 | ftsH | 6e-09 | 40.00% (75) | putative integral membrane peptidase |
| M. marinum M | MMAR_2166 | - | 2e-54 | 38.21% (335) | proline and glycine rich transmembrane protein |
| M. avium 104 | MAV_3436 | - | 8e-56 | 40.00% (325) | hypothetical protein MAV_3436 |
| M. smegmatis MC2 155 | MSMEG_5268 | - | 4e-43 | 34.75% (377) | hypothetical protein MSMEG_5268 |
| M. thermoresistible (build 8) | TH_4441 | - | 5e-27 | 31.11% (270) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1750 | - | 4e-52 | 37.94% (340) | proline and glycine rich transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_4673 | - | 9e-47 | 37.98% (337) | hypothetical protein Mvan_4673 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2590|M.bovis_AF2122/97 --------------------------------------------------
Rv2560|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2166|M.marinum_M --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MAV_3436|M.avium_104 --------------------------------------------------
MAB_0651c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5268|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4673|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
TH_4441|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 MLLMNRKNVIRMVTAIAVVVLLGWSFFYFSDDTRGYKFVDTSVAMSQING
Mb2590|M.bovis_AF2122/97 --------------------------------------------------
Rv2560|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2166|M.marinum_M --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MAV_3436|M.avium_104 --------------------------------------------------
MAB_0651c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5268|M.smegmatis_MC2_155 --------------------------------MTDQPPGN------NPPP
Mvan_4673|M.vanbaalenii_PYR-1 --------------------------------MTE-----------NPPP
Mflv_2044|M.gilvum_PYR-GCK --------------------------------MTE-----------NPPP
TH_4441|M.thermoresistible__bu -------------------------------MLSAVFIGRGVDAVRSPKP
MLBr_00222|M.leprae_Br4923 HNVKSAQIDDREQQLRLTLKKGNNDTDGSDKVITKYPTGYAVDLFNALSA
Mb2590|M.bovis_AF2122/97 ----MSQPPEHPGNPADPQGG--------------NQGAGSYPPP-----
Rv2560|M.tuberculosis_H37Rv ----MSQPPEHPGNPADPQGG--------------NQGAGSYPPP-----
MMAR_2166|M.marinum_M ----MSQPPENPGNQADPQGG--------------DQSTPGYPPPPNYGT
MUL_1750|M.ulcerans_Agy99 ----MSQPPENPGNQADPQDG--------------DQSTPGYPPPPNYGT
MAV_3436|M.avium_104 ----MSQPPEYPGTPPEPPPG--------------YGPPPGYGPPPGYGP
MAB_0651c|M.abscessus_ATCC_199 ----MTYPPQEPPTSGDPSAYD------------PNQPPPGYPNQP----
MSMEG_5268|M.smegmatis_MC2_155 PDGGYPPPPPPDGGYPPPPPPDGGYPPAQPGGFGPPPQ-GGYPPPPPPGG
Mvan_4673|M.vanbaalenii_PYR-1 --GGYPPPPP--GGYPPPPPP---------GGYQPPP------PPPSGGG
Mflv_2044|M.gilvum_PYR-GCK --GGYPPPPQ--GGYPPPPPSE--------GGYPPPPPEGGYPPPPPAGG
TH_4441|M.thermoresistible__bu AADAARPTIEGLTKLPEPVGPR--------VPTDAETVARINGMVQIAGG
MLBr_00222|M.leprae_Br4923 KNTKVTTAVNEGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGK
.
Mb2590|M.bovis_AF2122/97 -----------------GYGAPPPPP--------------------GYGP
Rv2560|M.tuberculosis_H37Rv -----------------GYGAPPPPP--------------------GYGP
MMAR_2166|M.marinum_M PPPPPPPGYGAPPAGPPGYGAPPPPPGYGTPPPPPGYGTPPPPPPPGYGQ
MUL_1750|M.ulcerans_Agy99 PPPPPPPGYGAPPAGPPGYGAPPPPP---------GYGTPPPPPPPGYGQ
MAV_3436|M.avium_104 PP---------------GYGTPPPPP-------------------PGYGP
MAB_0651c|M.abscessus_ATCC_199 -----------------PPGYQPPPP--------------------GYQP
MSMEG_5268|M.smegmatis_MC2_155 YP-------------PPPQGGFPPPP--------PGGYPPPPPPQGGSYP
Mvan_4673|M.vanbaalenii_PYR-1 YP-------------PPPSGGFPPPQ--------EGGYPPPQGP--GGYP
Mflv_2044|M.gilvum_PYR-GCK YQQ------------PPPGGAYPPPPG-------PGGYPPPPGQ--GGYP
TH_4441|M.thermoresistible__bu AL--------------LATGKLPRVAS-------AVLALSVVPGSLGGHM
MLBr_00222|M.leprae_Br4923 SRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPCRYQTLGAKIPK
*
Mb2590|M.bovis_AF2122/97 PPGTYLPPG---YN-APPPPPGYGPPPG--------PPPPGYPTHLQSSG
Rv2560|M.tuberculosis_H37Rv PPGTYLPPG---YN-APPPPPGYGPPPG--------PPPPGYPTHLQSSG
MMAR_2166|M.marinum_M APGGYAPPG---YNPPPPPPPGYGPPPAG------YPAQPGFGGPAKPP-
MUL_1750|M.ulcerans_Agy99 APGGYAPPG---YNPPPPPPPGYGPPPAG------YSTQPGFGGPAKPP-
MAV_3436|M.avium_104 ------PPG---YG---APPPGYGPPPG-------YGPPPGFGGPPKPA-
MAB_0651c|M.abscessus_ATCC_199 GYQAGPPPGGPQYQGAQFPPPGY--PPAG------YGYPQQRPWPPQGP-
MSMEG_5268|M.smegmatis_MC2_155 PPPPPGAAGYPPPGYPGGPGAGYPPAGGFGQ----PGGYAPVGAPGFGGA
Mvan_4673|M.vanbaalenii_PYR-1 PP-----AGYGPP------QGGFPPP---------AQGYPPVGGP---PA
Mflv_2044|M.gilvum_PYR-GCK PPP----GGYGMP--PAGFGGGYPPP---------GQGYPPVGGP---PS
TH_4441|M.thermoresistible__bu FWTESDPQRKAXX-----XTGGYPPA-----------GFPPPGGFG--AS
MLBr_00222|M.leprae_Br4923 GVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDL
.
Mb2590|M.bovis_AF2122/97 FSVGDAIS-----------------------------------WSWNRFT
Rv2560|M.tuberculosis_H37Rv FSVGDAIS-----------------------------------WSWNRFT
MMAR_2166|M.marinum_M FSVGEAIS-----------------------------------WAWNRFT
MUL_1750|M.ulcerans_Agy99 FSVGEAIS-----------------------------------WAWNRFT
MAV_3436|M.avium_104 FSVGEAFG-----------------------------------WAWNAFT
MAB_0651c|M.abscessus_ATCC_199 FSAGESWS-----------------------------------WSWAQVS
MSMEG_5268|M.smegmatis_MC2_155 YSVGDAFS-----------------------------------WAWNKFS
Mvan_4673|M.vanbaalenii_PYR-1 YSVGDAFN-----------------------------------WAWNKFS
Mflv_2044|M.gilvum_PYR-GCK LDIGAAFS-----------------------------------WSFNKFS
TH_4441|M.thermoresistible__bu YRFGDAFN-----------------------------------WAWSAFT
MLBr_00222|M.leprae_Br4923 FDQAKQNSPCIIFVDEIDAVGRQRGTGLGGGHDEREQTLNQLLVEMDGFG
. . .
Mb2590|M.bovis_AF2122/97 QNAVTLVVPVL--------------AYAVALAAVIGATAGLVVALSDRAT
Rv2560|M.tuberculosis_H37Rv QNAVTLVVPVL--------------AYAVALAAVIGATAGLVVALSDRAT
MMAR_2166|M.marinum_M QNAMALVVPIV--------------IYGLILSAVGGVMVGLFFAFSDRTS
MUL_1750|M.ulcerans_Agy99 QNAMALVVPIV--------------IYGLILSAVGGVMVGLFFAFSDRTS
MAV_3436|M.avium_104 KNPVALIVPTL--------------VYLVVLGGAS-----TLIGLSQDVG
MAB_0651c|M.abscessus_ATCC_199 KRFGTFIPPYL--------------VWFLAIGLPVGIVYAILMASLPQTS
MSMEG_5268|M.smegmatis_MC2_155 KHAVEMIVPAL--------------VFGLVYAILQGIVNGISGAFTS---
Mvan_4673|M.vanbaalenii_PYR-1 KNAMPLIVATL--------------VFGIVVIALQAIIN-IVQALVSPGD
Mflv_2044|M.gilvum_PYR-GCK KNAVPLIVPTL--------------VYALVIGVLGAVIFGLASLFPADYT
TH_4441|M.thermoresistible__bu RHAAPLMLAAL--------------AYVAIIFALSFLFSLVLTAFTPGG-
MLBr_00222|M.leprae_Br4923 DRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHSK
. :: . :
Mb2590|M.bovis_AF2122/97 TAYTNTSGVSS-ESVDIT---MTPAAGIVMFLGYIALFALVLYMHAGILT
Rv2560|M.tuberculosis_H37Rv TAYTNTSGVSS-ESVDIT---MTPAAGIVMFLGYIALFALVLYMHAGILT
MMAR_2166|M.marinum_M TTYTDAYGNTS-ETVNMT---MSPLASIVMFIGYLAVFAVVLFMHAGITT
MUL_1750|M.ulcerans_Agy99 TTYTDAYGNTS-ETVNMT---MSPLASIVMFIGYLAVFAVVLFMHAGITT
MAV_3436|M.avium_104 TS-GGGSGDDY-FTFTAN---LNGGGMALLVLGYLVAYLVGAFAQSAYLS
MAB_0651c|M.abscessus_ATCC_199 TSGYGGNSRSS-YSYSYEGPELSGGAIAIMILLYAVVFAVSLYVGACLIS
MSMEG_5268|M.smegmatis_MC2_155 ---TSSADGFE-LSMATG-------GGVVSIIGAIITLIVTAVIQAAYIS
Mvan_4673|M.vanbaalenii_PYR-1 TSYIADDSGFS-FSYATTG----VAGTIVAIVGWFLSLIVTAAIQSAFLG
Mflv_2044|M.gilvum_PYR-GCK SYSGADGAGMS-LDMGPA-------ATIILFLGLIMLFVVGGAISAAYMA
TH_4441|M.thermoresistible__bu -ATTVDPDSFF-DMFGVG-------GTLTMVVGVILLLFVSGVITSAFLN
MLBr_00222|M.leprae_Br4923 GKPIADDADLDGLAKRTVGMTGADLANVVNEAALLTARENGLVITGPALE
. .
Mb2590|M.bovis_AF2122/97 GCLDIADGKPVTIATFFRPR-------NLGLVLVTGLLIVALTFIGGLLC
Rv2560|M.tuberculosis_H37Rv GCLDIADGKPVTIATFFRPR-------NLGLVLVTGLLIVAVTFIGGLLC
MMAR_2166|M.marinum_M GCLDIADGKPVTIGSFFKPR-------NLGMVILTGLLVIVLTAIGSVLC
MUL_1750|M.ulcerans_Agy99 GCLDIADGKPVTIGSFFKPR-------NLGMVILTGLLVIVLTAIGSVLC
MAV_3436|M.avium_104 GCLDLADGRPVTIGSFFKPR-------NFGMVFLAALLVGILTSIASALC
MAB_0651c|M.abscessus_ATCC_199 ANLDVADGKPVSFGTFFRAR-------GFGLYVGAALLVGVGVLIG-SLL
MSMEG_5268|M.smegmatis_MC2_155 GVLEIANGQPVTIGSFFKPR-------NVGDVIIATVIVGVINFVVAAIL
Mvan_4673|M.vanbaalenii_PYR-1 GIFDIANGQQVAVGSFFRPR-------NVGNVIIAGLIVGVITTVGLFLC
Mflv_2044|M.gilvum_PYR-GCK GVLDIANGQQVEFGSFFKPR-------NIGAVVIASLIVGIATSIGYVLC
TH_4441|M.thermoresistible__bu GLLAIADGQQIELASFFRPR-------NVGSVVIATVIVGVLSYIGTALC
MLBr_00222|M.leprae_Br4923 EAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTI
. . * . :: : * : : :
Mb2590|M.bovis_AF2122/97 VIPG------------------------------------------LIFG
Rv2560|M.tuberculosis_H37Rv VIPG------------------------------------------LIFG
MMAR_2166|M.marinum_M IVPG------------------------------------------LIFG
MUL_1750|M.ulcerans_Agy99 IVPG------------------------------------------LIFG
MAV_3436|M.avium_104 FLPG------------------------------------------LILG
MAB_0651c|M.abscessus_ATCC_199 IIGG------------------------------------------VIFG
MSMEG_5268|M.smegmatis_MC2_155 LFPGFF------------------------VPGYLFVGVPVLLIASAIIA
Mvan_4673|M.vanbaalenii_PYR-1 IVPG------------------------------------------VIAS
Mflv_2044|M.gilvum_PYR-GCK IVPG------------------------------------------LIVS
TH_4441|M.thermoresistible__bu VVPG------------------------------------------LIVS
MLBr_00222|M.leprae_Br4923 LARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTTG
. * .
Mb2590|M.bovis_AF2122/97 FVAQFAVAFAVDRSTSPIDSVKASIETVGS--NIGGSVLSWLAQLTAVLV
Rv2560|M.tuberculosis_H37Rv FVAQFAVAFAVDRSTSPIDSVKASIETVGS--NIGGSVLSWLAQLTAVLV
MMAR_2166|M.marinum_M FLAQFAIIAAVDRSLSPIDSIKSSFATVRA--ELGNTALSWLVQYAVVLA
MUL_1750|M.ulcerans_Agy99 FLAQFAIIAAVDRSLSPIDSIKSSCATVRA--ELGNTALSWLVQYAVVLA
MAV_3436|M.avium_104 LFAQFTIAYAIDRSESAVKALSSSFSTVTA--NLANALLVWLAEFALVVV
MAB_0651c|M.abscessus_ATCC_199 FFAQYAVFFAIDRGLGPVDALKASFQLVKD--NLGQALVVFLITLGVAFG
MSMEG_5268|M.smegmatis_MC2_155 VLFLFTTVAVLDRNLSGVDAVKTSFELSKA--NFGTVFITAVVIFLLLLA
Mvan_4673|M.vanbaalenii_PYR-1 FLLMFTTIAVLDRNLAPMDAIKSSFETSKN--NVGPVLLTWLASVAVVFV
Mflv_2044|M.gilvum_PYR-GCK IFALFTTVFIVDRNLSAIDGIKASIAVAKA--NFLQVFLTWLIFNVLISV
TH_4441|M.thermoresistible__bu LFAMFTTVAVVDRNLSPIDGILASVDVVKK--NFGPAILVWLASGVLIFL
MLBr_00222|M.leprae_Br4923 AVSDIEKATKIARSMVTEFGMSSKLGAVRYGSEHGDPFLGRTMGTQADYS
. : *. .: :. : :
Mb2590|M.bovis_AF2122/97 G----ELLCFVGMLIGIPVA----ALIHVYTYRKLSGGQVVEAV--RPAP
Rv2560|M.tuberculosis_H37Rv G----ELLCFVGMLIGIPVA----ALIHVYTYRKLSGGQVVEAV--RPAP
MMAR_2166|M.marinum_M G----ELLCFVGMLVGVPVA----SLIQTYTWRKLSGGQVVELS--QPGP
MUL_1750|M.ulcerans_Agy99 G----ELLCFVGMLVGVPVA----SLIQTYTWRKLSGGQVVELS--QPGP
MAV_3436|M.avium_104 G----ALACGVGLLLAAPVA----ALVGIYAYRKLSGGQVAPPPGYQPGP
MAB_0651c|M.abscessus_ATCC_199 GFALTFITCGLGGIIAYPAAGALTGLIHVYTYRRLTGGTIAPAPV-----
MSMEG_5268|M.smegmatis_MC2_155 G----AIACGIGLLVAYPLV----ALIEVYAFRRLTGAPIAPPTQ-----
Mvan_4673|M.vanbaalenii_PYR-1 G----ALLCGVGLLVAAPLA----ALILVYAYRTLNGGFVAPAVP-----
Mflv_2044|M.gilvum_PYR-GCK G----SFVCYIGLIVTVPLA----VLYMVYAYRTLTGGYVAPATP-----
TH_4441|M.thermoresistible__bu G----SLLCGVGLLITGPLA----GLLVVCTFRRLTGAPVAPQAV-----
MLBr_00222|M.leprae_Br4923 HEVARDIDDEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPE
: : :: . . * .. :
Mb2590|M.bovis_AF2122/97 PVGWPPGP--------QLA-------------------------------
Rv2560|M.tuberculosis_H37Rv PVGWPPGP--------QLA-------------------------------
MMAR_2166|M.marinum_M PAGLPPGPPPGAPPGPQFG-------------------------------
MUL_1750|M.ulcerans_Agy99 PAGLPPGPPPGAPPGPQFG-------------------------------
MAV_3436|M.avium_104 PPGYQPGPPPGAPPA-----------------------------------
MAB_0651c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5268|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4673|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
TH_4441|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 LEGIFASVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPVP
Mb2590|M.bovis_AF2122/97 --------------------------------------------------
Rv2560|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2166|M.marinum_M --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MAV_3436|M.avium_104 --------------------------------------------------
MAB_0651c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5268|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4673|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
TH_4441|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 EPAFKAAIARASQAAEASHQAAQSDTDGPPGQGANGSHAGDRQRQHGPTQ
Mb2590|M.bovis_AF2122/97 --------------------------------------------------
Rv2560|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2166|M.marinum_M --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MAV_3436|M.avium_104 --------------------------------------------------
MAB_0651c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5268|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4673|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
TH_4441|M.thermoresistible__bu --------------------------------------------------
MLBr_00222|M.leprae_Br4923 PDYGAPPGWHAPGWPPQQPPDYWYPPEQQPSQSPYWPQPAPSYPGQAPPP
Mb2590|M.bovis_AF2122/97 ----------------------------------------
Rv2560|M.tuberculosis_H37Rv ----------------------------------------
MMAR_2166|M.marinum_M ----------------------------------------
MUL_1750|M.ulcerans_Agy99 ----------------------------------------
MAV_3436|M.avium_104 ----------------------------------------
MAB_0651c|M.abscessus_ATCC_199 ----------------------------------------
MSMEG_5268|M.smegmatis_MC2_155 ----------------------------------------
Mvan_4673|M.vanbaalenii_PYR-1 ----------------------------------------
Mflv_2044|M.gilvum_PYR-GCK ----------------------------------------
TH_4441|M.thermoresistible__bu ----------------------------------------
MLBr_00222|M.leprae_Br4923 YPSYPPCPSYPPPGQSAPDAGKPPAQLDEGVSPSNPPAHG