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MTVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLTNTTSRTRVQIAELLSAAGLAVPADEVIT AAMLTADHVITQHPGARCYLLNDGDITADMAGVDFVESLSDDPDVIILGGAGPQFDHVALSRVYELMAQG IPVVAMHRNAVWSTREGLRVDTGVYLAGMEQVSGRKAVAVGKPAPAGFQLAAERMGCEPDQVVMVGDDLH VDVLAAQVVGMTGVLVRTGKFRQDTLDRWAADQYAMQPAYVVDSVADLPPLLSGL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0641 | - | - | 100% (265) | HAD-superfamily hydrolase |
M. abscessus ATCC 19977 | MAB_2357 | - | 1e-13 | 25.99% (227) | HAD-superfamily hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1257c | - | 3e-90 | 60.22% (269) | hypothetical protein Mb1257c |
M. gilvum PYR-GCK | Mflv_0147 | - | 2e-99 | 65.43% (269) | Fis family transcriptional regulator |
M. tuberculosis H37Rv | Rv1225c | - | 3e-90 | 60.22% (269) | hypothetical protein Rv1225c |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | MMAR_2497 | - | 9e-15 | 26.29% (232) | phosphatase |
M. avium 104 | MAV_3079 | - | 1e-15 | 29.07% (227) | HAD-superfamily protein hydrolase, subfamily protein IIA |
M. smegmatis MC2 155 | MSMEG_0867 | - | 1e-100 | 66.17% (269) | hydrolase |
M. thermoresistible (build 8) | TH_1551 | - | 3e-15 | 26.87% (227) | PROBABLE PHOSPHATASE |
M. ulcerans Agy99 | MUL_1681 | - | 2e-15 | 26.29% (232) | phosphatase |
M. vanbaalenii PYR-1 | Mvan_0756 | - | 1e-100 | 65.80% (269) | HAD family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1257c|M.bovis_AF2122/97 ---MDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLT Rv1225c|M.tuberculosis_H37Rv ---MDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLT Mflv_0147|M.gilvum_PYR-GCK --------MAVGGVLFDIDGVLVTSWKPIPGAAETLRTLADNQIACTYLT Mvan_0756|M.vanbaalenii_PYR-1 --------MAIGGVLFDIDGVLVTSWKPIPGAAETLRTLADNQIACAYLT MSMEG_0867|M.smegmatis_MC2_155 --------MAIGGVLFDIDGVLVTSWQPIEGAAQTLRVLADNQIARSYLT MAB_0641|M.abscessus_ATCC_1997 --------MTVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLT MMAR_2497|M.marinum_M ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVTAR---KLFVT MUL_1681|M.ulcerans_Agy99 ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVTAR---KLFVT MAV_3079|M.avium_104 MSGVKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLPGR---ALFVT TH_1551|M.thermoresistible__bu ---VNSVAQHHDCLLLDLDGTVFRGHEPTPGAVESLRTVAAR---TLYVT :*:*:**. . . . **.::: : ::* Mb1257c|M.bovis_AF2122/97 NTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYP-GARCFLV Rv1225c|M.tuberculosis_H37Rv NTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYP-GARCFLV Mflv_0147|M.gilvum_PYR-GCK NTTTRTRSQIADLLTEAGMAVRADEVITAAVLTADYVRDRYP-DARCFLV Mvan_0756|M.vanbaalenii_PYR-1 NTTTRTRVQIADLLTEAGMAVRADEVITAAVLTADYVRDRYP-DARCFLV MSMEG_0867|M.smegmatis_MC2_155 NTTTKTRVQIAELLTAAGMDVSPDEVITAAVLTAEYVRDRFP-GARCFLV MAB_0641|M.abscessus_ATCC_1997 NTTSRTRVQIAELLSAAGLAVPADEVITAAMLTADHVITQHP-GARCYLL MMAR_2497|M.marinum_M NNASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVV MUL_1681|M.ulcerans_Agy99 NNASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVV MAV_3079|M.avium_104 NNASRSAGEVAAHLTELGFTATADDVATSAQSAAHLLAGQLPAGAPVLIV TH_1551|M.thermoresistible__bu NNASRAPGEVAEHLRSLGFAAAAEDVVTSAQSAARLLATTLPAGAPVLVL *.:::: ::* * *: . .::* *:. :* : * .: :: Mb1257c|M.bovis_AF2122/97 NNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVY Rv1225c|M.tuberculosis_H37Rv NNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVY Mflv_0147|M.gilvum_PYR-GCK NSGQIAEDMPGIDIVYSSEFTGPRAPERPDVVLLGGAGPEYSHLTLSWVY Mvan_0756|M.vanbaalenii_PYR-1 NSGQIGEDMPGIDLVYSSEFSGPRAPDAPDVVLLGGAGPEYSHLTLSWVY MSMEG_0867|M.smegmatis_MC2_155 NSGRIDEDMPGVDVVYSSEFSGPRAPEAPDVVLLGGAGPEYSHLTLSWVY MAB_0641|M.abscessus_ATCC_1997 NDGDITADMAGVDFVES-------LSDDPDVIILGGAGPQFDHVALSRVY MMAR_2497|M.marinum_M GTDALADEISAAGLRPVR-----RFEDQPDAVVQG-LSLTIGWPELAEAA MUL_1681|M.ulcerans_Agy99 GTDALADEISAAGLRPVR-----RFEDQPDAVVQG-LSLTIGWPELAEAA MAV_3079|M.avium_104 GTEALAGEIAAVGLRPVR-----RYDDGPVAVVQG-LSMTIGWPDLAEAA TH_1551|M.thermoresistible__bu GTEALAEEVRAVGLEPVR-----QFADRPVAVVQG-ISQQTGWPELAEAA . : :: . .. : * .:: * . . *: . Mb1257c|M.bovis_AF2122/97 GWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPA Rv1225c|M.tuberculosis_H37Rv GWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPA Mflv_0147|M.gilvum_PYR-GCK DWMAQGVPVVAMHRSTAWTTVDGLRVDTGMYLIGMEQTSGRKAAAVGKPA Mvan_0756|M.vanbaalenii_PYR-1 DWMAQGVPVVAMHRSTAWTTTDGLRIDTGMYLIGMEQTSGRKATAVGKPA MSMEG_0867|M.smegmatis_MC2_155 DWMAQGVPVVAMHRSTSWTTTDGLRVDTGMYLIGMEETSGRKATAVGKPA MAB_0641|M.abscessus_ATCC_1997 ELMAQGIPVVAMHRNAVWSTREGLRVDTGVYLAGMEQVSGRKAVAVGKPA MMAR_2497|M.marinum_M LAIRAGALWVAANVDKTLPTERGLLPGNGSLVAALRTATGAQPQVAGKPG MUL_1681|M.ulcerans_Agy99 LAIRAGALWVAANVDKTLPTERGLLPGNGSFVAALRTATGAQPQVAGKPG MAV_3079|M.avium_104 LAIRAGAVWVAANIDLTLPTERGLLPGNGSLVAAVAAATGATPQVAGKPA TH_1551|M.thermoresistible__bu LAIRAGAWWVATNADRTLPSERGLLPGNGAMIAALRAATDREPEVAGKPQ : * ** : . : ** ..* : .: . . . . *** Mb1257c|M.bovis_AF2122/97 AEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQ Rv1225c|M.tuberculosis_H37Rv AEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQ Mflv_0147|M.gilvum_PYR-GCK PEGFLSAANRLGVDPEEMFIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQD Mvan_0756|M.vanbaalenii_PYR-1 PEGFLSAAARLGVDPEEMYMVGDDLNNDVLAAQVVGMSGVLVRTGKFRQD MSMEG_0867|M.smegmatis_MC2_155 PEGFLAAASRLGVDPDEMYMIGDDLNNDVLAAQVVGMTGVLVRTGKFRQS MAB_0641|M.abscessus_ATCC_1997 PAGFQLAAERMGCEPDQVVMVGDDLHVDVLAAQVVGMTGVLVRTGKFRQD MMAR_2497|M.marinum_M PQLMKDAVGRGDFRAP--LVIGDRLDTDIEGANAAGLPSLMVLTGVSSAR MUL_1681|M.ulcerans_Agy99 PQLMKDAVGRGDFRAP--LVIGDRLDTDIEGANAAGLPSLMVLTGVSSAR MAV_3079|M.avium_104 PALLRDAAARGDFRAP--LVIGDRLDTDIEGANAAGLPSLLVLTGVNSAR TH_1551|M.thermoresistible__bu ATLMLDALSRGSFERP--LVVGDRLDTDIAGANNAGLPSLLVLTGVNDAA . : * * . ::** *. *: ..: .*:..::* ** Mb1257c|M.bovis_AF2122/97 TLDRWLAGASATRPHHVIDSVAGLPPLLGC-------------------- Rv1225c|M.tuberculosis_H37Rv TLDRWLAGASATRPHHVIDSVAGLPPLLGC-------------------- Mflv_0147|M.gilvum_PYR-GCK TLDRWAADEFAMQPNHVIDSIADLPALLGL-------------------- Mvan_0756|M.vanbaalenii_PYR-1 TLDRWAADEFAMQPNHVIDSVADFPALLGL-------------------- MSMEG_0867|M.smegmatis_MC2_155 VLDRWAADDFAMQPNHVIDSVADLPALLGL-------------------- MAB_0641|M.abscessus_ATCC_1997 TLDRWAADQYAMQPAYVVDSVADLPPLLSGL------------------- MMAR_2497|M.marinum_M DAVHADPVCRPTYIGHDLRSLRQDRATLAVAPQAGWRVQVD-GAAVTVSA MUL_1681|M.ulcerans_Agy99 DAVHADPVCRPTYIGHDLRSLRQDRATLAVAPQAGWRVQVD-GAAVTVSA MAV_3079|M.avium_104 DAVYAKPARRPTYIGHDLRALHQDAAALAVAPQPGWRVDVG-DTAITVSG TH_1551|M.thermoresistible__bu DAIWAVPGERPDLIAADLRSLHTPAEELRVAPHPAWRVDLNDGGTIRVTS . . : :: * Mb1257c|M.bovis_AF2122/97 -------------------------------------------------- Rv1225c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0147|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0756|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0867|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0641|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_2497|M.marinum_M NG--EQAGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWEGLHR MUL_1681|M.ulcerans_Agy99 NG--EQAGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWERLHR MAV_3079|M.avium_104 DGRDDGSGDGLSVVRAVASAVWGS----PDAG-TLPIRAGDDRARAALAR TH_1551|M.thermoresistible__bu TG--ADPGDPLSVVRAVAHAVWTADLVTTGDTAGLPIIGADDAARAALHR Mb1257c|M.bovis_AF2122/97 --------- Rv1225c|M.tuberculosis_H37Rv --------- Mflv_0147|M.gilvum_PYR-GCK --------- Mvan_0756|M.vanbaalenii_PYR-1 --------- MSMEG_0867|M.smegmatis_MC2_155 --------- MAB_0641|M.abscessus_ATCC_1997 --------- MMAR_2497|M.marinum_M WSLVHSE-- MUL_1681|M.ulcerans_Agy99 WSLVHSE-- MAV_3079|M.avium_104 WSLVRTD-- TH_1551|M.thermoresistible__bu WALSPFRID