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M. abscessus ATCC 19977 MAB_0641 (-)

annotation: HAD-superfamily hydrolase
coordinates: 643391 - 644188
length: 265

MTVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLTNTTSRTRVQIAELLSAAGLAVPADEVIT
AAMLTADHVITQHPGARCYLLNDGDITADMAGVDFVESLSDDPDVIILGGAGPQFDHVALSRVYELMAQG
IPVVAMHRNAVWSTREGLRVDTGVYLAGMEQVSGRKAVAVGKPAPAGFQLAAERMGCEPDQVVMVGDDLH
VDVLAAQVVGMTGVLVRTGKFRQDTLDRWAADQYAMQPAYVVDSVADLPPLLSGL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0641--100% (265)HAD-superfamily hydrolase
M. abscessus ATCC 19977MAB_2357-1e-1325.99% (227) HAD-superfamily hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1257c-3e-9060.22% (269) hypothetical protein Mb1257c
M. gilvum PYR-GCKMflv_0147-2e-9965.43% (269) Fis family transcriptional regulator
M. tuberculosis H37RvRv1225c-3e-9060.22% (269) hypothetical protein Rv1225c
M. leprae Br4923-----
M. marinum MMMAR_2497-9e-1526.29% (232) phosphatase
M. avium 104MAV_3079-1e-1529.07% (227) HAD-superfamily protein hydrolase, subfamily protein IIA
M. smegmatis MC2 155MSMEG_0867-1e-10066.17% (269) hydrolase
M. thermoresistible (build 8)TH_1551-3e-1526.87% (227) PROBABLE PHOSPHATASE
M. ulcerans Agy99MUL_1681-2e-1526.29% (232) phosphatase
M. vanbaalenii PYR-1Mvan_0756-1e-10065.80% (269) HAD family hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1257c|M.bovis_AF2122/97           ---MDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLT
Rv1225c|M.tuberculosis_H37Rv        ---MDVAHLMAAAVLFDIDGVLVLSWRAIPGAAETVRQLTHRGIACAYLT
Mflv_0147|M.gilvum_PYR-GCK          --------MAVGGVLFDIDGVLVTSWKPIPGAAETLRTLADNQIACTYLT
Mvan_0756|M.vanbaalenii_PYR-1       --------MAIGGVLFDIDGVLVTSWKPIPGAAETLRTLADNQIACAYLT
MSMEG_0867|M.smegmatis_MC2_155      --------MAIGGVLFDIDGVLVTSWQPIEGAAQTLRVLADNQIARSYLT
MAB_0641|M.abscessus_ATCC_1997      --------MTVGGVLFDIDGVLVTSWEPIDGAAQALKALENDDIRRCFLT
MMAR_2497|M.marinum_M               ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVTAR---KLFVT
MUL_1681|M.ulcerans_Agy99           ---MKNIAQEYDCLLIDLDGTVFRGSQPTEGAVESLDEVTAR---KLFVT
MAV_3079|M.avium_104                MSGVKTLAQQHDCLLIDLDGTAFRGRSPTEGAVQALARLPGR---ALFVT
TH_1551|M.thermoresistible__bu      ---VNSVAQHHDCLLLDLDGTVFRGHEPTPGAVESLRTVAAR---TLYVT
                                                 :*:*:**. . .  .  **.:::  :        ::*

Mb1257c|M.bovis_AF2122/97           NTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYP-GARCFLV
Rv1225c|M.tuberculosis_H37Rv        NTTTRTRRQIAEALGAAGIPVAADDVITAGVLTAEYLHGAYP-GARCFLV
Mflv_0147|M.gilvum_PYR-GCK          NTTTRTRSQIADLLTEAGMAVRADEVITAAVLTADYVRDRYP-DARCFLV
Mvan_0756|M.vanbaalenii_PYR-1       NTTTRTRVQIADLLTEAGMAVRADEVITAAVLTADYVRDRYP-DARCFLV
MSMEG_0867|M.smegmatis_MC2_155      NTTTKTRVQIAELLTAAGMDVSPDEVITAAVLTAEYVRDRFP-GARCFLV
MAB_0641|M.abscessus_ATCC_1997      NTTSRTRVQIAELLSAAGLAVPADEVITAAMLTADHVITQHP-GARCYLL
MMAR_2497|M.marinum_M               NNASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVV
MUL_1681|M.ulcerans_Agy99           NNASRSAGEVAVHLRELGFTATSEDVVTSAQSAAHLLAAALPPGSKVLVV
MAV_3079|M.avium_104                NNASRSAGEVAAHLTELGFTATADDVATSAQSAAHLLAGQLPAGAPVLIV
TH_1551|M.thermoresistible__bu      NNASRAPGEVAEHLRSLGFAAAAEDVVTSAQSAARLLATTLPAGAPVLVL
                                    *.::::  ::*  *   *: . .::* *:.  :*  :    * .:   ::

Mb1257c|M.bovis_AF2122/97           NNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVY
Rv1225c|M.tuberculosis_H37Rv        NNGDITEDLPGIDVVLSTEIGPEDCPEAPDVVVLGSAGPQFDHRTLSRVY
Mflv_0147|M.gilvum_PYR-GCK          NSGQIAEDMPGIDIVYSSEFTGPRAPERPDVVLLGGAGPEYSHLTLSWVY
Mvan_0756|M.vanbaalenii_PYR-1       NSGQIGEDMPGIDLVYSSEFSGPRAPDAPDVVLLGGAGPEYSHLTLSWVY
MSMEG_0867|M.smegmatis_MC2_155      NSGRIDEDMPGVDVVYSSEFSGPRAPEAPDVVLLGGAGPEYSHLTLSWVY
MAB_0641|M.abscessus_ATCC_1997      NDGDITADMAGVDFVES-------LSDDPDVIILGGAGPQFDHVALSRVY
MMAR_2497|M.marinum_M               GTDALADEISAAGLRPVR-----RFEDQPDAVVQG-LSLTIGWPELAEAA
MUL_1681|M.ulcerans_Agy99           GTDALADEISAAGLRPVR-----RFEDQPDAVVQG-LSLTIGWPELAEAA
MAV_3079|M.avium_104                GTEALAGEIAAVGLRPVR-----RYDDGPVAVVQG-LSMTIGWPDLAEAA
TH_1551|M.thermoresistible__bu      GTEALAEEVRAVGLEPVR-----QFADRPVAVVQG-ISQQTGWPELAEAA
                                    .   :  :: . ..            : * .:: *  .   .   *: . 

Mb1257c|M.bovis_AF2122/97           GWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPA
Rv1225c|M.tuberculosis_H37Rv        GWMLDGVPVVAMHRNMTWNTTDGLRIDTGMYLTGMEQACGKTATAIGKPA
Mflv_0147|M.gilvum_PYR-GCK          DWMAQGVPVVAMHRSTAWTTVDGLRVDTGMYLIGMEQTSGRKAAAVGKPA
Mvan_0756|M.vanbaalenii_PYR-1       DWMAQGVPVVAMHRSTAWTTTDGLRIDTGMYLIGMEQTSGRKATAVGKPA
MSMEG_0867|M.smegmatis_MC2_155      DWMAQGVPVVAMHRSTSWTTTDGLRVDTGMYLIGMEETSGRKATAVGKPA
MAB_0641|M.abscessus_ATCC_1997      ELMAQGIPVVAMHRNAVWSTREGLRVDTGVYLAGMEQVSGRKAVAVGKPA
MMAR_2497|M.marinum_M               LAIRAGALWVAANVDKTLPTERGLLPGNGSLVAALRTATGAQPQVAGKPG
MUL_1681|M.ulcerans_Agy99           LAIRAGALWVAANVDKTLPTERGLLPGNGSFVAALRTATGAQPQVAGKPG
MAV_3079|M.avium_104                LAIRAGAVWVAANIDLTLPTERGLLPGNGSLVAAVAAATGATPQVAGKPA
TH_1551|M.thermoresistible__bu      LAIRAGAWWVATNADRTLPSERGLLPGNGAMIAALRAATDREPEVAGKPQ
                                      :  *   ** : .    :  **  ..*  : .:  . .  . . *** 

Mb1257c|M.bovis_AF2122/97           AEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQ
Rv1225c|M.tuberculosis_H37Rv        AEGFLAAADRVGVDPQQMVMIGDDLHNDVLAAQAVGMTGVLVRTGKFRQQ
Mflv_0147|M.gilvum_PYR-GCK          PEGFLSAANRLGVDPEEMFIVGDDLNNDVLAGQVVGMTGVLVRTGKFRQD
Mvan_0756|M.vanbaalenii_PYR-1       PEGFLSAAARLGVDPEEMYMVGDDLNNDVLAAQVVGMSGVLVRTGKFRQD
MSMEG_0867|M.smegmatis_MC2_155      PEGFLAAASRLGVDPDEMYMIGDDLNNDVLAAQVVGMTGVLVRTGKFRQS
MAB_0641|M.abscessus_ATCC_1997      PAGFQLAAERMGCEPDQVVMVGDDLHVDVLAAQVVGMTGVLVRTGKFRQD
MMAR_2497|M.marinum_M               PQLMKDAVGRGDFRAP--LVIGDRLDTDIEGANAAGLPSLMVLTGVSSAR
MUL_1681|M.ulcerans_Agy99           PQLMKDAVGRGDFRAP--LVIGDRLDTDIEGANAAGLPSLMVLTGVSSAR
MAV_3079|M.avium_104                PALLRDAAARGDFRAP--LVIGDRLDTDIEGANAAGLPSLLVLTGVNSAR
TH_1551|M.thermoresistible__bu      ATLMLDALSRGSFERP--LVVGDRLDTDIAGANNAGLPSLLVLTGVNDAA
                                    .  :  *  * .       ::** *. *: ..: .*:..::* **     

Mb1257c|M.bovis_AF2122/97           TLDRWLAGASATRPHHVIDSVAGLPPLLGC--------------------
Rv1225c|M.tuberculosis_H37Rv        TLDRWLAGASATRPHHVIDSVAGLPPLLGC--------------------
Mflv_0147|M.gilvum_PYR-GCK          TLDRWAADEFAMQPNHVIDSIADLPALLGL--------------------
Mvan_0756|M.vanbaalenii_PYR-1       TLDRWAADEFAMQPNHVIDSVADFPALLGL--------------------
MSMEG_0867|M.smegmatis_MC2_155      VLDRWAADDFAMQPNHVIDSVADLPALLGL--------------------
MAB_0641|M.abscessus_ATCC_1997      TLDRWAADQYAMQPAYVVDSVADLPPLLSGL-------------------
MMAR_2497|M.marinum_M               DAVHADPVCRPTYIGHDLRSLRQDRATLAVAPQAGWRVQVD-GAAVTVSA
MUL_1681|M.ulcerans_Agy99           DAVHADPVCRPTYIGHDLRSLRQDRATLAVAPQAGWRVQVD-GAAVTVSA
MAV_3079|M.avium_104                DAVYAKPARRPTYIGHDLRALHQDAAALAVAPQPGWRVDVG-DTAITVSG
TH_1551|M.thermoresistible__bu      DAIWAVPGERPDLIAADLRSLHTPAEELRVAPHPAWRVDLNDGGTIRVTS
                                          .   .      : ::      *                      

Mb1257c|M.bovis_AF2122/97           --------------------------------------------------
Rv1225c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_0147|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0756|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0867|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0641|M.abscessus_ATCC_1997      --------------------------------------------------
MMAR_2497|M.marinum_M               NG--EQAGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWEGLHR
MUL_1681|M.ulcerans_Agy99           NG--EQAGDDLSIVRAVACAVWDA----QFDGRPFTVNGGDDHAWERLHR
MAV_3079|M.avium_104                DGRDDGSGDGLSVVRAVASAVWGS----PDAG-TLPIRAGDDRARAALAR
TH_1551|M.thermoresistible__bu      TG--ADPGDPLSVVRAVAHAVWTADLVTTGDTAGLPIIGADDAARAALHR
                                                                                      

Mb1257c|M.bovis_AF2122/97           ---------
Rv1225c|M.tuberculosis_H37Rv        ---------
Mflv_0147|M.gilvum_PYR-GCK          ---------
Mvan_0756|M.vanbaalenii_PYR-1       ---------
MSMEG_0867|M.smegmatis_MC2_155      ---------
MAB_0641|M.abscessus_ATCC_1997      ---------
MMAR_2497|M.marinum_M               WSLVHSE--
MUL_1681|M.ulcerans_Agy99           WSLVHSE--
MAV_3079|M.avium_104                WSLVRTD--
TH_1551|M.thermoresistible__bu      WALSPFRID