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GNPVIVEATRSAIGKRGGWLAGLHPAELLGSIQRSVIARAGLDPNEVEQVIGGCVTQFGEQGGHITRQAW LHAGLPEATGATTIDCQCGSAQQANHLIAGLIYSGAIDTGIACGIESMSRVPLGANVGGTGIPRPDSWDI DMPNQFEAAERIAKRRGITRADVDGLGVRSQALAAQAWAEGRFDREITPLDAPQVDKEGNPTGETKTVNR DQGLRETTLESLGNLKPVIAEGIHTAGTSSQISDGAAAVLLMDSDKAKALGLRPRARIVSQALVGAEPYY HLDGPVQSTQRVLDRAGMKIGDIDVVEINEAFASVVLSWAAVHKPDFDRVNVNGGAIALGHPVGSTGSRL ITTALHELERTDKSTALITMCAGGALSTGTIIERV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0612c | - | - | 100% (386) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_3455c | - | 3e-84 | 44.42% (403) | putative acyl-CoA thiolase |
| M. abscessus ATCC 19977 | MAB_0600 | - | 4e-72 | 39.80% (397) | acetyl-CoA acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3576 | fadA5 | 1e-167 | 75.70% (391) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_1507 | - | 1e-168 | 75.45% (387) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv3546 | fadA5 | 1e-167 | 75.70% (391) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | MLBr_02162 | fadA | 5e-67 | 39.22% (408) | acetyl-CoA acetyltransferase |
| M. marinum M | MMAR_5033 | fadA5 | 1e-167 | 74.68% (391) | acetyl-CoA acetyltransferase FadA5 |
| M. avium 104 | MAV_0615 | - | 1e-171 | 76.42% (386) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_5996 | - | 1e-170 | 76.49% (387) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_0166 | fadA6 | 3e-79 | 43.22% (398) | PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6 |
| M. ulcerans Agy99 | MUL_4107 | fadA5 | 1e-166 | 74.42% (391) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5259 | - | 1e-171 | 77.78% (387) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3576|M.bovis_AF2122/97 --MGYPVIVEATRSPIGK-RNGWLSGLHATELLGAVQKAVVDKA-GIQSG
Rv3546|M.tuberculosis_H37Rv --MGYPVIVEATRSPIGK-RNGWLSGLHATELLGAVQKAVVDKA-GIQSG
MMAR_5033|M.marinum_M --MGNPVIVEATRSPIGK-RNGWLSGLHATELLGAVQKALVHKA-GLSSG
MUL_4107|M.ulcerans_Agy99 --MGNPVIVEATRSPIGK-RNGWLSGLHATELLGAVQKALVHKA-GLSSG
MAV_0615|M.avium_104 --MGNPVIVAATRSPIGK-RNGWLSGLHATELLGAVQKAVVEKA-GID--
Mflv_1507|M.gilvum_PYR-GCK --MGTPVIVEATRSPIGK-RNGWLSGLHATELLGAVQKALVEKA-GID--
MSMEG_5996|M.smegmatis_MC2_155 --MGNPVIVEATRSPIGK-RNGWLSGLHATELLGAVQKALVEKA-GID--
Mvan_5259|M.vanbaalenii_PYR-1 --MGNPVIVEATRSPIGK-RNGWLSGLHATELLGAVQKALVEKA-GIE--
MAB_0612c|M.abscessus_ATCC_199 --MGNPVIVEATRSAIGK-RGGWLAGLHPAELLGSIQRSVIARA-GLD--
MLBr_02162|M.leprae_Br4923 -MSEEAFIYEAIRTPRGKQKNGSLHEVKPVSLVVGLVEELRKRNPDLDEN
TH_0166|M.thermoresistible__bu MAMTEAYIVDAVRTPVGK-RNGGLSGAHPADMAAHVIKTLVGRH-DFDPA
. * * *:. ** :.* * :...: : . : : .:.
Mb3576|M.bovis_AF2122/97 LHAGDVEQVIGGCVTQFGEQSNNISRVAWLTAGLPEHVGATTVDCQCGSG
Rv3546|M.tuberculosis_H37Rv LHAGDVEQVIGGCVTQFGEQSNNISRVAWLTAGLPEHVGATTVDCQCGSG
MMAR_5033|M.marinum_M LQPGDVEQVIGGCVTQFGEQSNNISRVAWLTAGLPDHVGATTVDCQCGSG
MUL_4107|M.ulcerans_Agy99 LQPGDVEQVIGGCVTQFGEQSNNISRVAWLTAGLPGHVGATTVDCQCGSG
MAV_0615|M.avium_104 --AGDVEQVIGGCVTQYAEQSNNISRTAWLTAGLPDHVGATTVDCQCGSG
Mflv_1507|M.gilvum_PYR-GCK --AGDVEQVIGGCVTQYGEQSNNITRVGWLTAGLPEHVGATTIDCQCGSA
MSMEG_5996|M.smegmatis_MC2_155 --PGSVEQIIGGCVTQYGEQSNNITRVGWLTAGLPEHVGATTIDCQCGSA
Mvan_5259|M.vanbaalenii_PYR-1 --AGMVEQVIGGCVTQFGEQSNNITRVGWLTAGLPEHVGATTIDCQCGSA
MAB_0612c|M.abscessus_ATCC_199 --PNEVEQVIGGCVTQFGEQGGHITRQAWLHAGLPEATGATTIDCQCGSA
MLBr_02162|M.leprae_Br4923 ----LISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGGVQLNRFCASG
TH_0166|M.thermoresistible__bu ----AIDDVIFGCLDNIGSQAGDIARTAALAAGLPESVPGVTIDRQCGSA
:.::* **: ..*...*:* * **** . .. :: *.*.
Mb3576|M.bovis_AF2122/97 QQANHLIAGLIAAGAIDVGIACGIEAMSRVGLGANAGPDRSLIRAQS---
Rv3546|M.tuberculosis_H37Rv QQANHLIAGLIAAGAIDVGIACGIEAMSRVGLGANAGPDRSLIRAQS---
MMAR_5033|M.marinum_M QQANHLIAGLIAIGAIDIGIACGIEAMSRVGLGANAGPDRSAIRAKS---
MUL_4107|M.ulcerans_Agy99 QQANHLIAGLIAIGAIDIGIACGIEAMSRVGLGANAGPDRSAIRAKS---
MAV_0615|M.avium_104 QQANHLIAGLIATGAIDVGIACGIEAMSRVGLGANAGPDHN-WRAES---
Mflv_1507|M.gilvum_PYR-GCK QQANHLVAGLIATGAIDIGIACGIEAMSRVGLGANAGPDRGLIRASS---
MSMEG_5996|M.smegmatis_MC2_155 QQANHLVAGLIATGAIDIGIACGIEAMSRVGLGANAGPDRSLIRASS---
Mvan_5259|M.vanbaalenii_PYR-1 QQANHLIAGLIATGAIDIGIACGIEAMSRVGLGANAGPDRSIIRASS---
MAB_0612c|M.abscessus_ATCC_199 QQANHLIAGLIYSGAIDTGIACGIESMSRVPLGANVG-GTGIPRPDS---
MLBr_02162|M.leprae_Br4923 LEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGAMGLDPATN----
TH_0166|M.thermoresistible__bu QQAVHFAAQGVMSGTVDLIVAGGVQKMSQFPILSAFAAGEPYGATDPWTG
:* : * : * * :* *:: **:. : : . ..
Mb3576|M.bovis_AF2122/97 -------WDIDLPNQFEAAERIAKRRGITREDVDVFGLESQRRAQRAWAE
Rv3546|M.tuberculosis_H37Rv -------WDIDLPNQFEAAERIAKRRGITREDVDVFGLESQRRAQRAWAE
MMAR_5033|M.marinum_M -------WDIDMPNQFEAAERIAKRRGITRQDIDAFGLESQLRAKRAWDE
MUL_4107|M.ulcerans_Agy99 -------WDIDMPNQFEAAERIAKRRGITREDIDAFGLESQLRAKRAWDE
MAV_0615|M.avium_104 -------WDIDMPNQFEAAERIAKRRGITREDIDEFGLASQAKAKQAWDE
Mflv_1507|M.gilvum_PYR-GCK -------WDIDMPNQFEAAERIAKRRGITRADLDAFGLASQTKAKQAWAE
MSMEG_5996|M.smegmatis_MC2_155 -------WDIDMPNQFEAAERIAQRRGITRADVDALGLASQRKAKQAWDE
Mvan_5259|M.vanbaalenii_PYR-1 -------WDIDMPNQFEAAERIAKRRGITRADVDALGVASQAKAKQAWAE
MAB_0612c|M.abscessus_ATCC_199 -------WDIDMPNQFEAAERIAKRRGITRADVDGLGVRSQALAAQAWAE
MLBr_02162|M.leprae_Br4923 -------YDVMFVPQGIGADLIATIEGFSRDDVDVYALRSQEKAAAAWSG
TH_0166|M.thermoresistible__bu CEGWQARYGDQEISQFRGAEMIAEHWKLSREDNEKFALESHRRAVAAIEA
:. * .*: ** ::* * : .: *: * *
Mb3576|M.bovis_AF2122/97 GRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLR-ETTMAGLGELKPVL
Rv3546|M.tuberculosis_H37Rv GRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLR-ETTMAGLGELKPVL
MMAR_5033|M.marinum_M HRFDREISPIEAPVLDEQKQPTSELHMVSRDQGLR-DTTMAGLSELKPVM
MUL_4107|M.ulcerans_Agy99 HRFDREISPIEAPVLDEQKQPTSELHMVSRDQGLR-DTTMAGLSELKPVM
MAV_0615|M.avium_104 GRFDREISPIVAPALDENKQPTAERVTISRDQGLR-ETTLSGLSALKPVI
Mflv_1507|M.gilvum_PYR-GCK GRFDREISPISAPVLDENKRPTDEWAPVTRDQGLR-DTTAEALASLKPVM
MSMEG_5996|M.smegmatis_MC2_155 GRFDREISPISAPVLDENKQPTSEWAPVTRDQGLR-DTTPEALASLKPVL
Mvan_5259|M.vanbaalenii_PYR-1 GRFDREISPISAPVLDENKQPTAEWAPVTRDQGLR-DTTAEALAALNPVM
MAB_0612c|M.abscessus_ATCC_199 GRFDREITPLDAPQVDKEGNPTGETKTVNRDQGLR-ETTLESLGNLKPVI
MLBr_02162|M.leprae_Br4923 GYFAKSVVPVRDQNG---------LLILDHDEHMRPDTSKEGLAKLKPAF
TH_0166|M.thermoresistible__bu GYFDKEITPYADAT---------------VDEGPRPDTSLEKMASLPTLI
* :.: * *: * :*: :. * . :
Mb3576|M.bovis_AF2122/97 EG----G------------------IHTAGTSSQISDGAAAVLWMDEAVA
Rv3546|M.tuberculosis_H37Rv EG----G------------------IHTAGTSSQISDGAAAVLWMDEAVA
MMAR_5033|M.marinum_M EG----G------------------IHTAGTSSQISDGAAAVLWMDEEKA
MUL_4107|M.ulcerans_Agy99 EG----G------------------IHTAGTSSQISDGAAAVLWMDEEKA
MAV_0615|M.avium_104 EG----G------------------IHTAGTSSQISDGAAAVLWMDEDKA
Mflv_1507|M.gilvum_PYR-GCK EG----A------------------MHTAGTSSQISDGAAAVLWMDEEKA
MSMEG_5996|M.smegmatis_MC2_155 DG----G------------------IHTAGTSSQISDGAAAVLWMDEDKA
Mvan_5259|M.vanbaalenii_PYR-1 EG----G------------------IHTAGTSSQISDGAAAVLWMDEDKA
MAB_0612c|M.abscessus_ATCC_199 AE----G------------------IHTAGTSSQISDGAAAVLLMDSDKA
MLBr_02162|M.leprae_Br4923 EGLAAMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSEAVG
TH_0166|M.thermoresistible__bu EG----G------------------VLTAAVASQISDGAAALLVASKDAV
. : *.. :* * **** :: ..
Mb3576|M.bovis_AF2122/97 RAHGLTPRARIVAQALVGAEPYYHLDGPVQSTAKVLEKAGMKIGDIDIVE
Rv3546|M.tuberculosis_H37Rv RAHGLTPRARIVAQALVGAEPYYHLDGPVQSTAKVLEKAGMKIGDIDIVE
MMAR_5033|M.marinum_M RALGLRPRARIVSQALVGAEPYYHLDGPVQSTAKVLEKAGMKMGDIDIVE
MUL_4107|M.ulcerans_Agy99 RALGLRPRARIVSQALVGAEPYYHLDGPVQSTAKVLEKAGMKMGDIDIVE
MAV_0615|M.avium_104 KALGLRPRARIISQALVGAEPYYHLDGPVQSTAKVLEKAGMKMGDIDITE
Mflv_1507|M.gilvum_PYR-GCK KALGLKPRARIVAQANVGAETYYHLDGPVQSTAKVLEKAGMKLGDIDLVE
MSMEG_5996|M.smegmatis_MC2_155 KALGLKPRARIVAQANVGAETYYHLDGPVQSTARVLEKAGMKLGDIDLVE
Mvan_5259|M.vanbaalenii_PYR-1 KALGLKPRARIVAQANVGAETYYHLDGPVQSTARVLEKAGMKMGDIDITE
MAB_0612c|M.abscessus_ATCC_199 KALGLRPRARIVSQALVGAEPYYHLDGPVQSTQRVLDRAGMKIGDIDVVE
MLBr_02162|M.leprae_Br4923 KSQGLTPRARMVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFE
TH_0166|M.thermoresistible__bu DRFNLTPRARIHHMSVRGADPVMMLTAPIPATQHALKRAGMSIDDIDAVE
.* ****: : **:. * .* :* :.*.:**:.:.*** *
Mb3576|M.bovis_AF2122/97 INEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCTGSRLITTALHE
Rv3546|M.tuberculosis_H37Rv INEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCTGSRLITTALHE
MMAR_5033|M.marinum_M INEAFASVVLSWARVHEPDMAKVNVNGGAIALGHPVGCTGSRLITTALHE
MUL_4107|M.ulcerans_Agy99 INEAFASVVLSWARVHEPEMAKVNVNGGAIALGHPVGCTGSRLITTALHE
MAV_0615|M.avium_104 INEAFASVVLSWARVHEPDMARVNVNGGAIALGHPVGCTGSRLITTALHE
Mflv_1507|M.gilvum_PYR-GCK INEAFASVVLSWAQVHGADMDKVNVNGGAIALGHPVGSTGARLITTALHE
MSMEG_5996|M.smegmatis_MC2_155 INEAFASVVLSWAQVHNADMDKVNVNGGAIALGHPVGSTGARLITTALHE
Mvan_5259|M.vanbaalenii_PYR-1 INEAFASVVLSWARVHEADMDTVNVNGGAIALGHPVGSTGARLITTALHE
MAB_0612c|M.abscessus_ATCC_199 INEAFASVVLSWAAVHKPDFDRVNVNGGAIALGHPVGSTGSRLITTALHE
MLBr_02162|M.leprae_Br4923 LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDE
TH_0166|M.thermoresistible__bu INEAFAPVVLAWLAELGADPARVNPNGGAIALGHPIGCTGARLMTSLLHH
:*****.*** : :* ******:***:*.**: :: : :..
Mb3576|M.bovis_AF2122/97 LERTDQSLALITMCAGGALSTGTIIERI
Rv3546|M.tuberculosis_H37Rv LERTDQSLALITMCAGGALSTGTIIERI
MMAR_5033|M.marinum_M LERTDQSTALITMCAGGALSTGTILERI
MUL_4107|M.ulcerans_Agy99 LERTDQSTALITMCAGGALSTGTILERI
MAV_0615|M.avium_104 LERSDQTTALITMCAGGALSTGTIIERI
Mflv_1507|M.gilvum_PYR-GCK LERTDRSTALVTMCAGGALSTGTIIERI
MSMEG_5996|M.smegmatis_MC2_155 LERTGKGTALITMCAGGALSTGTIIERI
Mvan_5259|M.vanbaalenii_PYR-1 LERTDKTTALITMCAGGALSTGTIIERI
MAB_0612c|M.abscessus_ATCC_199 LERTDKSTALITMCAGGALSTGTIIERV
MLBr_02162|M.leprae_Br4923 LERCNARRALVTLCIGAGMGVATIIERV
TH_0166|M.thermoresistible__bu LERTGGRYGLQTMCEGGGQANVTIIERL
*** . .* *:* *.. . **:**: