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MADTQYPFNNDGLDQWGAEETIEVDKDRLIAYAEATNDPIEEHRKGQVAAPVFAIVPIFQSLVGTTMSVV PYQLIPRVVHGEQFFKFHRPIKPGDTLVAKSKMTGYEGMENGTRGTVYAETRDAAGDLVNEQYVTFFFRK YDVGETRGELGPTFVLDEAVKVNSPTASLTQHVDDDQTFRYGPAAGDPMPIHLDNDAAVAAGLPGIIAHG LCTMAFTSWAALTELADSRTERLKELAVRFAKPVLPGQDITTNFWTNGAAGTFSYETNVGEDLVIKNGHA VIA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0379 | - | - | 100% (283) | hypothetical protein MAB_0379 |
| M. abscessus ATCC 19977 | MAB_2949c | - | 3e-92 | 56.90% (290) | hypothetical protein MAB_2949c |
| M. abscessus ATCC 19977 | MAB_0621c | - | 1e-13 | 25.88% (228) | MaoC family dehydrogenase/dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3568 | - | 2e-13 | 24.02% (254) | dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1518 | - | 6e-15 | 30.00% (190) | dehydratase |
| M. tuberculosis H37Rv | Rv3538 | - | 2e-13 | 24.02% (254) | dehydrogenase |
| M. leprae Br4923 | MLBr_02566 | - | 9e-06 | 25.67% (261) | hypothetical protein MLBr_02566 |
| M. marinum M | MMAR_1155 | - | 9e-13 | 26.70% (221) | hypothetical protein MMAR_1155 |
| M. avium 104 | MAV_4337 | - | 9e-13 | 28.57% (182) | MaoC family protein |
| M. smegmatis MC2 155 | MSMEG_5943 | - | 1e-10 | 25.00% (228) | putative peroxisomal multifunctional enzyme type 2 |
| M. thermoresistible (build 8) | TH_2980 | - | 2e-13 | 29.57% (186) | PUTATIVE MaoC domain protein dehydratase |
| M. ulcerans Agy99 | MUL_0920 | - | 5e-13 | 26.70% (221) | hypothetical protein MUL_0920 |
| M. vanbaalenii PYR-1 | Mvan_2340 | - | 2e-88 | 55.99% (284) | dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0379|M.abscessus_ATCC_1997 ---MADT-----QYPFNNDGLDQWGAEETIEVDKDRLIAYAEATNDPIEE
Mvan_2340|M.vanbaalenii_PYR-1 ---MTDTRAAVADPAFDDSGLDTWTDDDHFEVTRERIAEYAAATNDPIEA
Mflv_1518|M.gilvum_PYR-GCK ---MPINLDEAIGAELPPVEFSWTSSDVQLYHLGLGAGADPMDTRELRYL
MSMEG_5943|M.smegmatis_MC2_155 ---MPIDLDKALGAELEPIEFSWTSSDIQLYHLGLGAGADPMDERELRYL
Mb3568|M.bovis_AF2122/97 ---MPIDLDVALGAQLPPVEFSWTSTDVQLYQLGLGAGSDPMNPRELSYL
Rv3538|M.tuberculosis_H37Rv ---MPIDLDVALGAQLPPVEFSWTSTDVQLYQLGLGAGSDPMNPRELSYL
MMAR_1155|M.marinum_M ---MAIDP-GAVGATTEPMSFEWKDRETLLYALGVGAGIDDLSFT-TENS
MUL_0920|M.ulcerans_Agy99 ---MAIDP-GAVGATTEPMSFEWKDRETLLYALGVGAGIDDLSFT-TENS
MAV_4337|M.avium_104 ---MAIDP-SAVGAVTEPLLFEWTDRDTLLYALGVGAGVDDLAFT-TENS
TH_2980|M.thermoresistible__bu --------------------------------------------------
MLBr_02566|M.leprae_Br4923 MTFGFVLRRLRRHFSVKENTVNQPSGLKNILRAIVGALPLLPRTDQLPSR
MAB_0379|M.abscessus_ATCC_1997 HRKGQVAAPVFAIVPIFQSLVGTTMSVVP--YQLIPRVVHGEQFFK--FH
Mvan_2340|M.vanbaalenii_PYR-1 HRNGDVAPPVFAIVPVFESMMMPTVDVLP--VELVPRVVHGEQDFY--FH
Mflv_1518|M.gilvum_PYR-GCK VDDTPQVLPTFGNVAQSFHMTEPPAVKFPGIDIELSKVLHASEAVT--VP
MSMEG_5943|M.smegmatis_MC2_155 VDGTPQVLPTFGNVAASFHMTEPPKVQFPGIDIELSKVLHASEAVS--VP
Mb3568|M.bovis_AF2122/97 ADDTPQVLPTFGNVAATFHLTTPPTVQFPGIDIELSKVLHASERVE--VP
Rv3538|M.tuberculosis_H37Rv ADDTPQVLPTFGNVAATFHLTTPPTVQFPGIDIELSKVLHASERVE--VP
MMAR_1155|M.marinum_M HDIAQQVLPTYAVICCPAFGAAGKIGTFN-----HAMLLHGSQGIR--LH
MUL_0920|M.ulcerans_Agy99 HDIAQQVLPTYAVICCPAFGAAGKIGTLN-----HAMLLHGSQGIR--LH
MAV_4337|M.avium_104 HGIDQQVLPTYAVICCPAFGAAGLVGKFN-----WAMLLHGSQSIR--LH
TH_2980|M.thermoresistible__bu ---------------------MGLVGEFD-----FARLLHGSQSIR--LF
MLBr_02566|M.leprae_Br4923 TVTIEELPIDHTNVSAYASVTGLRYGNHVPLTYPFALTFPAMMSLVTGFD
. . . . .
MAB_0379|M.abscessus_ATCC_1997 RPIKPGDTLVAKSKMTGYEGMENGTRGTVYAETR---DAAGDLVNEQYVT
Mvan_2340|M.vanbaalenii_PYR-1 RPIRPGDKLVSRGKMIGYEGLDNGTRAAILIECR---TEGGELVNEQYVT
Mflv_1518|M.gilvum_PYR-GCK GPIPAAGTGIAVTRFTEIWDKG--KAAVIWSETEVKDPD-GTLLWTQKRS
MSMEG_5943|M.smegmatis_MC2_155 GPIPTSGTAKSVQRFTEIWDKG--KAAVIVSETTVTDPS-GKVLWTTKRS
Mb3568|M.bovis_AF2122/97 APLPPSGSARAVTRFTDIWDKG--KAAVICSETTATTPD-GLLLWTQKRS
Rv3538|M.tuberculosis_H37Rv APLPPSGSARAVTRFTDIWDKG--KAAVICSETTATTPD-GLLLWTQKRS
MMAR_1155|M.marinum_M APLPAAGKLSVVSEVADIQDKGEGKNAVIMLRGRGTDPETGTLIAETFTT
MUL_0920|M.ulcerans_Agy99 APLPAAGKLSVVSEVADIQDKGEGKNAVIMLRGRGTDPETGTLIAETFTT
MAV_4337|M.avium_104 APLPPAGKLSVVSEVADIQDKGEGKNAILVLRGRGTEPDSGQLIAETLTT
TH_2980|M.thermoresistible__bu APLRPNGRLSVVAEVADIQDKGPGKNAIVVFKGTGTDPDTGQVVAETVST
MLBr_02566|M.leprae_Br4923 FPFAAMGSVHTENHITQYRPIAVTDVVGVQVHAENLREHRKGLLVDLVTD
*: . . .. : . ::
MAB_0379|M.abscessus_ATCC_1997 FFFRKYDVGETRGELGPTFVLDEAVKVNSPTAS--------LTQHVDDDQ
Mvan_2340|M.vanbaalenii_PYR-1 CFVRGFNAGKKIGELSPSHKFDEALRERDPLAR--------VAQHIDHDQ
Mflv_1518|M.gilvum_PYR-GCK IFAR--GEGGFGGDRGP-STSTAAPD-RAPDLE--------LTVPTSPQQ
MSMEG_5943|M.smegmatis_MC2_155 IFAR--GEGGFGGERGP-STSFEPPS-RAPDFE--------ISLPTLPQQ
Mb3568|M.bovis_AF2122/97 IYAR--GEGGFGGKRGP-SGSDVAPE-RAPDLQ--------VAMPILPQQ
Rv3538|M.tuberculosis_H37Rv IYAR--GEGGFGGKRGP-SGSDVAPE-RAPDLQ--------VAMPILPQQ
MMAR_1155|M.marinum_M LVIR--QAGGFGGVPGERPAAPEIPD-REPDAR--------VVLPTREDQ
MUL_0920|M.ulcerans_Agy99 LVIR--QAGGFGGVPGERPAAPEIPD-REPDAR--------VVLPTREDQ
MAV_4337|M.avium_104 LVIR--GEGGFGGMPGQRPIAPEFPD-REPDAR--------IALPTREDQ
TH_2980|M.thermoresistible__bu AVIR--GAGGFGGEPGQRPPAPEIPD-RAPDAE--------LALPTREDQ
MLBr_02566|M.leprae_Br4923 VSVGNDTAWHQVTTFLHLQRTSLSDEPKPPSQKQPKLLPPSAVLQITPRQ
. * *
MAB_0379|M.abscessus_ATCC_1997 TFRYGPAAGDPMPIHLDNDAA-VAAGLPGIIAHGLCTMAFTSWAALTELA
Mvan_2340|M.vanbaalenii_PYR-1 TFRYSPASGDPMPIHLDEEVA-RDAGLPGIIAHGLCTMAFTSWAVLTEVA
Mflv_1518|M.gilvum_PYR-GCK ALLYR-MCGDRNPLHSDPEFA-AAAGFPRPILHGLCTYGMTCKALVDNLL
MSMEG_5943|M.smegmatis_MC2_155 ALLYR-LCGDRNPLHSDPTFA-KAAGFDRPILHGLCTYGIGCKAIVDNLL
Mb3568|M.bovis_AF2122/97 ALLYR-LCGDRNPLHSDPEFA-AAAGFPRPILHGLCTYGMTCKAIVDALL
Rv3538|M.tuberculosis_H37Rv ALLYR-LCGDRNPLHSDPEFA-AAAGFPRPILHGLCTYGMTCKAIVDALL
MMAR_1155|M.marinum_M ALIYR-LSGDRNPLHSDPWFAKELAGFPKPILHGLCTYGVAGRALVAELG
MUL_0920|M.ulcerans_Agy99 ALIYR-LSGDRNPLHSDPWFAKELAGFPKPILHGLCTYGVAGRALVAELG
MAV_4337|M.avium_104 ALIYR-LSGDRNPLHSDPWFARELAGFPKPILHGLCTYGVSGRALVAELG
TH_2980|M.thermoresistible__bu ALIYR-LSGDRNPLHSDPWFARELAGFPRPILHGLCTYGVAGRALVAELG
MLBr_02566|M.leprae_Br4923 IRRYAAVGGDHNPIHTNPIVA-KLFGFPTTIAHGMFSAAAVLANIEARLP
* ** *:* : * *: * **: : . :
MAB_0379|M.abscessus_ATCC_1997 DSRTERLKELAVRFAKPVLPGQDITTNFWTN----GAAG--TFSYETN--
Mvan_2340|M.vanbaalenii_PYR-1 GSDVGRLRRFAVRFSKMVLPGDDLETSIWKRDSGTAAAGVTTYQFETTRA
Mflv_1518|M.gilvum_PYR-GCK DGDVRGLKSYGARMAGVVFPGETLRVSVWKDG--------GSYTATVTAP
MSMEG_5943|M.smegmatis_MC2_155 DGDVSRVASYGARFAGVVFPGETLSANIWKED--------GKFIGVLTAP
Mb3568|M.bovis_AF2122/97 DSDATAVAGYGARFAGVAYPGETLTVNVWKDG--------RRLVASVVAP
Rv3538|M.tuberculosis_H37Rv DSDATAVAGYGARFAGVAYPGETLTVNVWKDG--------RRLVASVVAP
MMAR_1155|M.marinum_M GGVAANITSIDARFTKPVFPGETLTTLIWRTEP-----GKAVYRTVVAGT
MUL_0920|M.ulcerans_Agy99 GGVAANITSIDARFTKPVFPGETLTTLIWRTEP-----GKAVYRTVVAGT
MAV_4337|M.avium_104 GGVAANITSIASRFTSPVFPGETLTTLIWRTEP-----GKAVFRTEASNP
TH_2980|M.thermoresistible__bu GGDATRITAISARFTAPVFPGDTLTTAIWRTGE-----GQAVFRTEAANP
MLBr_02566|M.leprae_Br4923 D-----AVHYSARFVKPVVLPATTGLYVDESAG--------NWDLTLRNI
. *: . .
MAB_0379|M.abscessus_ATCC_1997 VGEDLVIKNGHAVIA----
Mvan_2340|M.vanbaalenii_PYR-1 GGAEKAITDGLAEIAD---
Mflv_1518|M.gilvum_PYR-GCK ERDNAVALAGVEFVPA---
MSMEG_5943|M.smegmatis_MC2_155 SRDNTVVLSGVELVPA---
Mb3568|M.bovis_AF2122/97 TRDNAVVLSGVELVPA---
Rv3538|M.tuberculosis_H37Rv TRDNAVVLSGVELVPA---
MMAR_1155|M.marinum_M DGSDARVVLDDGAVEYVQG
MUL_0920|M.ulcerans_Agy99 DGSDARVVLDDGAVEYVQG
MAV_4337|M.avium_104 DGSNTRVVLDDGAVEYA--
TH_2980|M.thermoresistible__bu DGSDARLVLEDGVAEYAG-
MLBr_02566|M.leprae_Br4923 AKGYPHLAGTVQGV-----