For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PDEELAFDDEGLNVWTDEDRFEVTRERLVEYARATNDPIPAHLAGDVAPPVFAIVPVFESLLTPTVDVAP VELIPRVVHGEQDFHFHRPIRPGDKLVSRGKMIGYEGLEKGTRAAVYLECRTEDGELVNEQYVTCFFRGH DAGKKVGELSPGHKFDEVLRGQAPLAKIVQHVDSDQTYRYSPAAGDPMPIHLDEEIARDAGLPGIIAHGL CTMAFTSWAVLTEVGGSDVNRLKRFAVRFSKMVFPGDDLETRIWQTGRIGYATSYAFETARTGENGEEFA ITDGLAVIAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2949c | - | - | 100% (291) | hypothetical protein MAB_2949c |
| M. abscessus ATCC 19977 | MAB_0379 | - | 3e-92 | 56.90% (290) | hypothetical protein MAB_0379 |
| M. abscessus ATCC 19977 | MAB_0621c | - | 1e-17 | 32.38% (210) | MaoC family dehydrogenase/dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3421c | - | 3e-18 | 33.50% (197) | dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4895 | - | 2e-14 | 28.51% (221) | dehydratase |
| M. tuberculosis H37Rv | Rv3389c | - | 2e-18 | 33.50% (197) | dehydrogenase |
| M. leprae Br4923 | MLBr_01908 | - | 1e-07 | 30.08% (133) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
| M. marinum M | MMAR_1155 | - | 2e-16 | 30.96% (197) | hypothetical protein MMAR_1155 |
| M. avium 104 | MAV_4337 | - | 6e-18 | 31.89% (185) | MaoC family protein |
| M. smegmatis MC2 155 | MSMEG_5943 | - | 3e-11 | 27.36% (212) | putative peroxisomal multifunctional enzyme type 2 |
| M. thermoresistible (build 8) | TH_2980 | - | 2e-21 | 31.96% (219) | PUTATIVE MaoC domain protein dehydratase |
| M. ulcerans Agy99 | MUL_0920 | - | 1e-16 | 30.96% (197) | hypothetical protein MUL_0920 |
| M. vanbaalenii PYR-1 | Mvan_2340 | - | 1e-130 | 77.85% (289) | dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3421c|M.bovis_AF2122/97 MAIDPN-SIGAVTEPMLFEWTDRDTLLYAIGVGAGTGDLAFT-TENSHGI
Rv3389c|M.tuberculosis_H37Rv MAIDPN-SIGAVTEPMLFEWTDRDTLLYAIGVGAGTGDLAFT-TENSHGI
MMAR_1155|M.marinum_M MAIDPG-AVGATTEPMSFEWKDRETLLYALGVGAGIDDLSFT-TENSHDI
MUL_0920|M.ulcerans_Agy99 MAIDPG-AVGATTEPMSFEWKDRETLLYALGVGAGIDDLSFT-TENSHDI
MAV_4337|M.avium_104 MAIDPS-AVGAVTEPLLFEWTDRDTLLYALGVGAGVDDLAFT-TENSHGI
TH_2980|M.thermoresistible__bu --------------------------------------------------
Mflv_4895|M.gilvum_PYR-GCK MPIDPG-ALGASTPPAIFRWTDRDTLLYALGVGAGTDDLAFT-TENSHDV
MSMEG_5943|M.smegmatis_MC2_155 MPIDLDKALGAELEPIEFSWTSSDIQLYHLGLGAGADPMDERELRYLVDG
MAB_2949c|M.abscessus_ATCC_199 MPDE-----ELAFDDEGLNVWTDEDRFEVTRERLVEYARATNDPIPAHLA
Mvan_2340|M.vanbaalenii_PYR-1 MTDTRAAVADPAFDDSGLDTWTDDDHFEVTRERIAEYAAATNDPIEAHRN
MLBr_01908|M.leprae_Br4923 MALKTD-IRGMVWRYSDYFIVGREQCREFARAIKCDHPAYFSEDAAAELG
Mb3421c|M.bovis_AF2122/97 DQQVLPTYAVICCPAFGAAAKVGTFN-----PAALLHGSQGIRLHAPLPA
Rv3389c|M.tuberculosis_H37Rv DQQVLPTYAVICCPAFGAAAKVGTFN-----PAALLHGSQGIRLHAPLPA
MMAR_1155|M.marinum_M AQQVLPTYAVICCPAFGAAGKIGTFN-----HAMLLHGSQGIRLHAPLPA
MUL_0920|M.ulcerans_Agy99 AQQVLPTYAVICCPAFGAAGKIGTLN-----HAMLLHGSQGIRLHAPLPA
MAV_4337|M.avium_104 DQQVLPTYAVICCPAFGAAGLVGKFN-----WAMLLHGSQSIRLHAPLPP
TH_2980|M.thermoresistible__bu ------------------MGLVGEFD-----FARLLHGSQSIRLFAPLRP
Mflv_4895|M.gilvum_PYR-GCK TQQVLPTYAVIACSPFAAITKIGSFD-----FSRLLHGSQRIRVFSPLPA
MSMEG_5943|M.smegmatis_MC2_155 TPQVLPTFGNVAASFHMTEPPKVQFPGIDIELSKVLHASEAVSVPGPIPT
MAB_2949c|M.abscessus_ATCC_199 GDVAPPVFAIVPVFESLLTPTVDVAP--VELIPRVVHGEQDFHFHRPIRP
Mvan_2340|M.vanbaalenii_PYR-1 GDVAPPVFAIVPVFESMMMPTVDVLP--VELVPRVVHGEQDFYFHRPIRP
MLBr_01908|M.leprae_Br4923 YDAIVAPLTFVTIFAKYVQLDFFRNVDVGMETMQIVQVDQRFVFHKPVLV
::: .: . . *:
Mb3421c|M.bovis_AF2122/97 AGKLSVVTEVADIQDKGEGKNAIVVLRGRGCDPESGSLVAETLTTLVLRG
Rv3389c|M.tuberculosis_H37Rv AGKLSVVTEVADIQDKGEGKNAIVVLRGRGCDPESGSLVAETLTTLVLRG
MMAR_1155|M.marinum_M AGKLSVVSEVADIQDKGEGKNAVIMLRGRGTDPETGTLIAETFTTLVIRQ
MUL_0920|M.ulcerans_Agy99 AGKLSVVSEVADIQDKGEGKNAVIMLRGRGTDPETGTLIAETFTTLVIRQ
MAV_4337|M.avium_104 AGKLSVVSEVADIQDKGEGKNAILVLRGRGTEPDSGQLIAETLTTLVIRG
TH_2980|M.thermoresistible__bu NGRLSVVAEVADIQDKGPGKNAIVVFKGTGTDPDTGQVVAETVSTAVIRG
Mflv_4895|M.gilvum_PYR-GCK AGALSVVSEVADIQDKGEGKNAVVMLKGTGRDPDTGAVVAETLTTLVLRG
MSMEG_5943|M.smegmatis_MC2_155 SGTAKSVQRFTEIWDK--GKAAVIVSETTVTDP-SGKVLWTTKRSIFARG
MAB_2949c|M.abscessus_ATCC_199 GDKLVSRGKMIGYEGLEKGTRAAVYLECR---TEDGELVNEQYVTCFFRG
Mvan_2340|M.vanbaalenii_PYR-1 GDKLVSRGKMIGYEGLDNGTRAAILIECR---TEGGELVNEQYVTCFVRG
MLBr_01908|M.leprae_Br4923 GDKLWAR---MDIHSVSERFGADIVVTKNSCTSDDGELVMEAYTTLMGQQ
. . * : . * :: : . :
Mb3421c|M.bovis_AF2122/97 QGG---FGGARGERPAAPEFPDRHPDARIDMLTREDQALIYR-LSGDRNP
Rv3389c|M.tuberculosis_H37Rv QGG---FGGARGERPAAPEFPDRHPDARIDMPTREDQALIYR-LSGDRNP
MMAR_1155|M.marinum_M AGG---FGGVPGERPAAPEIPDREPDARVVLPTREDQALIYR-LSGDRNP
MUL_0920|M.ulcerans_Agy99 AGG---FGGVPGERPAAPEIPDREPDARVVLPTREDQALIYR-LSGDRNP
MAV_4337|M.avium_104 EGG---FGGMPGQRPIAPEFPDREPDARIALPTREDQALIYR-LSGDRNP
TH_2980|M.thermoresistible__bu AGG---FGGEPGQRPPAPEIPDRAPDAELALPTREDQALIYR-LSGDRNP
Mflv_4895|M.gilvum_PYR-GCK EGG---FGGQPGSRPTAPPVPDREPDARVSLPTREDQALIYR-LSGDRNP
MSMEG_5943|M.smegmatis_MC2_155 EGG---FGGERGP-STSFEPPSRAPDFEISLPTLPQQALLYR-LCGDRNP
MAB_2949c|M.abscessus_ATCC_199 HDAGKKVGELSPGHKFDEVLRGQAPLAKIVQHVDSDQTYRYSPAAGDPMP
Mvan_2340|M.vanbaalenii_PYR-1 FNAGKKIGELSPSHKFDEALRERDPLARVAQHIDHDQTFRYSPASGDPMP
MLBr_01908|M.leprae_Br4923 GDN----------------------SSQLKWDKESGQVIRSA--------
. .: *.
Mb3421c|M.bovis_AF2122/97 LHSDPWFATQLAGFPKPILHGLCTYGVAGRALVAELGGGVAANITSIAAR
Rv3389c|M.tuberculosis_H37Rv LHSDPWFATQLAGFPKPILHGLCTYGVAGRALVAELGGGVAANITSIAAR
MMAR_1155|M.marinum_M LHSDPWFAKELAGFPKPILHGLCTYGVAGRALVAELGGGVAANITSIDAR
MUL_0920|M.ulcerans_Agy99 LHSDPWFAKELAGFPKPILHGLCTYGVAGRALVAELGGGVAANITSIDAR
MAV_4337|M.avium_104 LHSDPWFARELAGFPKPILHGLCTYGVSGRALVAELGGGVAANITSIASR
TH_2980|M.thermoresistible__bu LHSDPWFARELAGFPRPILHGLCTYGVAGRALVAELGGGDATRITAISAR
Mflv_4895|M.gilvum_PYR-GCK LHSDPWFA-QLAGFRRPILHGLCTYGVAGRALVSELGGGDATRITAIAAR
MSMEG_5943|M.smegmatis_MC2_155 LHSDPTFA-KAAGFDRPILHGLCTYGIGCKAIVDNLLDGDVSRVASYGAR
MAB_2949c|M.abscessus_ATCC_199 IHLDEEIA-RDAGLPGIIAHGLCTMAFTSWAVLTEVGGSDVNRLKRFAVR
Mvan_2340|M.vanbaalenii_PYR-1 IHLDEEVA-RDAGLPGIIAHGLCTMAFTSWAVLTEVAGSDVGRLRRFAVR
MLBr_01908|M.leprae_Br4923 --------------------------------------------------
Mb3421c|M.bovis_AF2122/97 FTKPVFPGETLSTVIWRTEPGRAVFRTEVAGSDGAEAR-----VVLDDGA
Rv3389c|M.tuberculosis_H37Rv FTKPVFPGETLSTVIWRTEPGRAVFRTEVAGSDGAEAR-----VVLDDGA
MMAR_1155|M.marinum_M FTKPVFPGETLTTLIWRTEPGKAVYRTVVAGTDGSDAR-----VVLDDGA
MUL_0920|M.ulcerans_Agy99 FTKPVFPGETLTTLIWRTEPGKAVYRTVVAGTDGSDAR-----VVLDDGA
MAV_4337|M.avium_104 FTSPVFPGETLTTLIWRTEPGKAVFRTEASNPDGSNTR-----VVLDDGA
TH_2980|M.thermoresistible__bu FTAPVFPGDTLTTAIWRTGEGQAVFRTEAANPDGSDAR-----LVLEDGV
Mflv_4895|M.gilvum_PYR-GCK FVAPVLPGDTLTTSIWRVESGRGVFRTEAANADGSDSR-----SVLEDGE
MSMEG_5943|M.smegmatis_MC2_155 FAGVVFPGETLSANIWK-EDGKFIG---VLTAPSRDNT-----VVLSG--
MAB_2949c|M.abscessus_ATCC_199 FSKMVFPGDDLETRIWQTG---RIGYATSYAFETARTGENGEEFAITDGL
Mvan_2340|M.vanbaalenii_PYR-1 FSKMVLPGDDLETSIWKRDSGTAAAGVTTYQFETTRAG--GAEKAITDGL
MLBr_01908|M.leprae_Br4923 --------------------------------------------------
Mb3421c|M.bovis_AF2122/97 VEYVAG--
Rv3389c|M.tuberculosis_H37Rv VEYVAG--
MMAR_1155|M.marinum_M VEYVQG--
MUL_0920|M.ulcerans_Agy99 VEYVQG--
MAV_4337|M.avium_104 VEYA----
TH_2980|M.thermoresistible__bu AEYAG---
Mflv_4895|M.gilvum_PYR-GCK VEFVDNQR
MSMEG_5943|M.smegmatis_MC2_155 VELVPA--
MAB_2949c|M.abscessus_ATCC_199 AVIAD---
Mvan_2340|M.vanbaalenii_PYR-1 AEIAD---
MLBr_01908|M.leprae_Br4923 --------