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MIDFSIPEELAAKAQRVREFVTETVIPYERDPRLTAHGPTEELRDELVGKARAAGLLTVQAPESYGGWGL SHIGQAVIFEAAGWSTLGPIAMNCAAPDEGNMFLLGKITNEEQSEKFLRPVIEGYQRSAFAMTEPDGAGS DPSQLKTSATFDGQNFVINGRKWLITGARGAKTWIIMANLEANDHLPEGPTLFLCDGETEGIVIERIMNT MDRNYAEGHAVVRFDNLTLPREALLGETGQAFRYAQLRLAPARLTHCMRWLGAASRAQDIAVDYARTRTS FGKTIGEHQGVSFMLADNEIALHQCRLTIWHACWMMDNGAKGRHESSMAKSFVSEELFKVTDRCVQVLGG IGISDETPVEMIFRDMRAFRLYDGPTEVHKYAIGRQVLRTPRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0328 | - | - | 100% (393) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0255 | - | 2e-61 | 38.31% (402) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4911c | - | 6e-50 | 33.24% (343) | acyl-CoA dehydrogenase FadE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0159c | fadE2 | 4e-59 | 36.62% (385) | acyl-CoA dehydrogenase FADE2 |
| M. gilvum PYR-GCK | Mflv_0734 | - | 2e-61 | 37.59% (399) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv0154c | fadE2 | 4e-59 | 36.62% (385) | acyl-CoA dehydrogenase FADE2 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 5e-35 | 27.18% (390) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_0374 | fadE2 | 6e-62 | 35.93% (398) | acyl-CoA dehydrogenase FadE2 |
| M. avium 104 | MAV_5144 | - | 8e-58 | 35.43% (398) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0102 | - | 6e-59 | 35.93% (398) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_2913 | - | 6e-65 | 36.25% (400) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_4790 | fadE1 | 9e-51 | 31.49% (397) | acyl-CoA dehydrogenase FadE1 |
| M. vanbaalenii PYR-1 | Mvan_0116 | - | 5e-62 | 36.63% (404) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0734|M.gilvum_PYR-GCK -------------MDFAMSAKAQDYHDRLTDFMTEHVFPAEESYHSYRAE
Mvan_0116|M.vanbaalenii_PYR-1 MDLTVYTCHIVAVMDFSMSAKAQDYHDRLTDFMTESVFPAEESYHAYRAE
MSMEG_0102|M.smegmatis_MC2_155 ----------MAGMDFAMSAKAADYHKRLTDFMVEFVFPAEAEYHAYREE
Mb0159c|M.bovis_AF2122/97 -----------------MSAKAIDYRTRLSDFMTEHVFGAEADYDDYRRA
Rv0154c|M.tuberculosis_H37Rv -----------------MSAKAIDYRTRLSDFMTEHVFGAEADYDDYRRA
MMAR_0374|M.marinum_M -------MSYRGGMDFAMSAKAIDYHQRLSDFMTEYVFPAEADYDKYRED
MAV_5144|M.avium_104 -------------MDFAMSAKASDYHKRLTDFMTEHVFAAEAEYDKYRHE
TH_2913|M.thermoresistible__bu ------------MWDFATEPEVERELEWIREFVKEEIEPLET------LD
MUL_4790|M.ulcerans_Agy99 ------------MWDFETDPEYQAKLDWVQEFMVNELEPLDL------VA
MAB_0328|M.abscessus_ATCC_1997 ------------MIDFSIPEELAAKAQRVREFVTETVIPYERD-----PR
MLBr_00737|M.leprae_Br4923 ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
. :: :
Mflv_0734|M.gilvum_PYR-GCK AGPKDHTVPPVVEELK--KQAKERGLWNLFLPSVSG---LSNLEYAPLAE
Mvan_0116|M.vanbaalenii_PYR-1 AGPDDHTVPPVVEELK--KLAKARGLWNLFLPSESG---LSNLEYAPLAE
MSMEG_0102|M.smegmatis_MC2_155 KGPKDHTVPPVVEELK--VKAKDRGLWNLFLPAESG---LTNLEYAPLAE
Mb0159c|M.bovis_AF2122/97 AGPADHTAPPIIEELK--TKAKDRGLWNLFLSAESG---LTNLEYAPLAE
Rv0154c|M.tuberculosis_H37Rv AGPADHTAPPIIEELK--TKAKDRGLWNLFLSAESG---LTNLEYAPLAE
MMAR_0374|M.marinum_M AGPNDHTVPPVVEELK--ANAKARGLWNLFLPAESG---LTNLEYAPLAE
MAV_5144|M.avium_104 AGPHDHTVPPVVEQLK--VKAKQQGLWNLFLPAESG---LTNLEYAPLAE
TH_2913|M.thermoresistible__bu LD--DAAMTRAMEPLK--QQVKDRGLWAAHLPPELGGQGFGQVRLALMHE
MUL_4790|M.ulcerans_Agy99 LDPYDKKNPEMMAVLRPLQQVKNQGLWAAHLRPEVGGQGFGQVKLALLNE
MAB_0328|M.abscessus_ATCC_1997 LTAHGPTEELRDELVG---KARAAGLLTVQAPESYGGWGLSHIGQAVIFE
MLBr_00737|M.leprae_Br4923 VDQRARFPEEALAALN------ASGFNAIHVPEEYGGQGADSVAACIVIE
: *: * : . : *
Mflv_0734|M.gilvum_PYR-GCK LTGWSMEIAPEATNCAAPDTGNMETLHLFATEEQRTQWLEPLLAGEIRSA
Mvan_0116|M.vanbaalenii_PYR-1 LTGWSMEIAPEATNCAAPDTGNMETLHLFATEEQRKQWLEPLLAGEIRSA
MSMEG_0102|M.smegmatis_MC2_155 ITGWSMEIAPEALNCQAPDTGNMETLHLFANEAQRKQWLEPLLAGEIRSA
Mb0159c|M.bovis_AF2122/97 MTGWSMEIAPEALNCAAPDTGNMEILHMFGTEQQRAQWLRPLLDGKIRSA
Rv0154c|M.tuberculosis_H37Rv MTGWSMEIAPEALNCAAPDTGNMEILHMFGTEQQRAQWLRPLLDGKIRSA
MMAR_0374|M.marinum_M LTGWSLEIAPEALNCAAPDTGNMEILHMFGTDEQRRQWLDPLLHGEIRSA
MAV_5144|M.avium_104 ITGWSLEIAPEALNCAAPDTGNMETLHLFATEEQRKQWLEPLLAGEIRSA
TH_2913|M.thermoresistible__bu ILGRS-HLAPIVFGNQAPDSGNAELLAVAGTPEQKRRWLDPLLAGTIRSC
MUL_4790|M.ulcerans_Agy99 ILGRS-RWAPSVFGCQAPDSGNAEILALFGTEDQKARYLQPLLDGEITSC
MAB_0328|M.abscessus_ATCC_1997 AAGWS-TLGPIAMNCAAPDEGNMFLLGKITNEEQSEKFLRPVIEGYQRSA
MLBr_00737|M.leprae_Br4923 EVARVDASASLIP---AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMAS
. .. * : . * . : * .: :.
Mflv_0734|M.gilvum_PYR-GCK FAMTEPAVASSDARNIETTMLRDGDDYVINGRKWWITGAADPRCKILIVM
Mvan_0116|M.vanbaalenii_PYR-1 FAMTEPAVASSDARNIETTMLRDGDDYVINGRKWWITGAADPRCKILIVM
MSMEG_0102|M.smegmatis_MC2_155 FAMTEPAVASSDARNIETTMLRDGDHYVINGRKWWITGAADPRCKILIVM
Mb0159c|M.bovis_AF2122/97 FSMTEPAVASSDARNIETTISRDGADYVINGRKWWTSGAADPRCKILIVM
Rv0154c|M.tuberculosis_H37Rv FSMTEPAVASSDARNIETTISRDGADYVINGRKWWTSGAADPRCKILIVM
MMAR_0374|M.marinum_M FSMTEPAVASSDARNIETTISRDGADYIINGRKWWTSGAADPRCKILIVM
MAV_5144|M.avium_104 FSMTEPAVASSDARNIETSIVRDGADYVINGRKWWTSGAADPRCKILIVM
TH_2913|M.thermoresistible__bu YAMTEPGAGA-DPTMLTTTARLAGDEWILNGRKWFASNAS--IADLFIVM
MUL_4790|M.ulcerans_Agy99 YSMTEPQGGS-DPGSFVTAATRDGDSWIINGEKWFSTNAK--HASFFIVM
MAB_0328|M.abscessus_ATCC_1997 FAMTEPDGAGSDPSQLKTSATFDGQNFVINGRKWLITGARG--AKTWIIM
MLBr_00737|M.leprae_Br4923 YALSE-REAGSDAASMRTRAKADGDDWILNGFKCWITNGG--KSTWYTVM
::::* .. *. : * * :::** * :.. . :*
Mflv_0734|M.gilvum_PYR-GCK GRTNPDGPSHRQQSMILVPTDTPGVSIERSLPVFGW----QDQHG-HCEI
Mvan_0116|M.vanbaalenii_PYR-1 GRTNPDGPSHRQQSMILVPADTPGVDIQRSLPVFGW----QDQHG-HCEI
MSMEG_0102|M.smegmatis_MC2_155 GRTNPDAAAHQQQSMILVPVDTPGVDIQRSLPVFGW----QDQHG-HCEI
Mb0159c|M.bovis_AF2122/97 GRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGW----QDRHG-HCEI
Rv0154c|M.tuberculosis_H37Rv GRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGW----QDRHG-HCEI
MMAR_0374|M.marinum_M GRTNPDAAAHQQQSMILVPTDTPGVTIARSTPVFGW----QDQHG-HCEV
MAV_5144|M.avium_104 GRTNPDAASHQQQSMVLVPMDTPGVTVVRSTPVFGW----QDQHG-HCEI
TH_2913|M.thermoresistible__bu AVTDPEAARHQRASMFLVPAGTPGLVVERDIPTMEHPYPRPPVYGNHAEV
MUL_4790|M.ulcerans_Agy99 AVTNPQARTYEKMSLFIVPAETPGIEIVRNVGVGTE----SSKHASHGYV
MAB_0328|M.abscessus_ATCC_1997 ANLEANDHLPEGPTLFLCDGETEGIVIERIMNTMDR----NYAEG-HAVV
MLBr_00737|M.leprae_Br4923 AVTDPDKGAN-GISAFIVHKDDEGFSIGPKEKKLGIK------GSPTTEL
. :.: : .: *. : . :
Mflv_0734|M.gilvum_PYR-GCK TFDNVRVPASNLLDEEGSGFAIAQARLGPGRIHHCMRAIGAAERALALMV
Mvan_0116|M.vanbaalenii_PYR-1 VFDNVRVPASNLLDEEGSGFAIAQARLGPGRIHHCMRAIGAAERALALMI
MSMEG_0102|M.smegmatis_MC2_155 VFNDVRVPAENLLDVEGSGFAIAQARLGPGRIHHCMRAIGAAERALTLMV
Mb0159c|M.bovis_AF2122/97 DYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALALMV
Rv0154c|M.tuberculosis_H37Rv DYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALALMV
MMAR_0374|M.marinum_M VYDNVRVPATNLLGEEGTGFAIAQARLGPGRIHHCMRALGGAERALALMV
MAV_5144|M.avium_104 VYDNVRVPVTNLLGEEGSGFAIAQARLGPGRIHHCMRALGGAERALALMV
TH_2913|M.thermoresistible__bu SLTDVRVPAENLLGERGRGFALAQTRLGPGRIHHCMRWLGQSERALEMLC
MUL_4790|M.ulcerans_Agy99 RYHDVRVPADHVLGGEGQAFMTAQTRLGGGRIHHAMRTIALARRAFDMMC
MAB_0328|M.abscessus_ATCC_1997 RFDNLTLPREALLGETGQAFRYAQLRLAPARLTHCMRWLGAASRAQDIAV
MLBr_00737|M.leprae_Br4923 YFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAI
. :* ::. * .* * * * : :. : *
Mflv_0734|M.gilvum_PYR-GCK DRVQTRIAFGKPLAEQGVVREAIAKSRNDIEQTRMLCHKAAWTIDQHGNK
Mvan_0116|M.vanbaalenii_PYR-1 DRVQTRIAFGKPLAEQGVVREAIAKSRNEIEQTRLLCHKAAWTIDQQGNK
MSMEG_0102|M.smegmatis_MC2_155 DRVQKRVAFGKPLAEQGVVREAIAKSRNEIDQARLLCEKAAWTIDLQGNK
Mb0159c|M.bovis_AF2122/97 NRVRNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQHGNK
Rv0154c|M.tuberculosis_H37Rv NRVRNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQHGNK
MMAR_0374|M.marinum_M DRARNRVAFGRPLAEQGVVQQAIAKSRNEIDQARLLCEKAAWTIDRHGNK
MAV_5144|M.avium_104 DRAQKRVAFGRPLAEQGVVRESIAKSRNEIDQARLLCEKAAWTIDQHGNK
TH_2913|M.thermoresistible__bu ERAVSRTIHGSLLSEKQMIQDWVAESVAERQAARLMTLHAAWKID-TEG-
MUL_4790|M.ulcerans_Agy99 ERAVSRQTRHGRLSDLQMTQEKVADSWIQIEQFRLLVLRTAWLID-KHHD
MAB_0328|M.abscessus_ATCC_1997 DYARTRTSFGKTIGEHQGVSFMLADNEIALHQCRLTIWHACWMMDNGAKG
MLBr_00737|M.leprae_Br4923 VYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPD
. * :. :*. . *: :. :
Mflv_0734|M.gilvum_PYR-GCK SKDAQLLVAQIKAVAPQMACDVIDRAIQVHGGAGVSDDFPLARLYSWHRA
Mvan_0116|M.vanbaalenii_PYR-1 SKDAQLLVAQIKAVAPQMACDVIDRAIQVHGGAGVCDDFPLARLYSWHRA
MSMEG_0102|M.smegmatis_MC2_155 --AAHVLVSQIKSVAPQVACNVLDRAIQVHGAAGVGDDFPLARLYAWHRA
Mb0159c|M.bovis_AF2122/97 --EARHLVAMIKAVAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGWHRA
Rv0154c|M.tuberculosis_H37Rv --EARHLVAMIKAVAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGWHRA
MMAR_0374|M.marinum_M --EARHLVAMIKAVAPQVACDVIDRAIQVHGAAGVSNDTPLARLYSWHRA
MAV_5144|M.avium_104 --AAHLLVSQIKAVAPKVACDVIDRAIQVHGAAGVSDDTVLARLYGWHRA
TH_2913|M.thermoresistible__bu VRGALTEIAMIKYWGARVLYNVIDRAIQLHGSLGYSCDMPLEFMYRQARA
MUL_4790|M.ulcerans_Agy99 YQKVRRDIAAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMVAAES
MAB_0328|M.abscessus_ATCC_1997 ----RHESSMAKSFVSEELFKVTDRCVQVLGGIGISDETPVEMIFRDMRA
MLBr_00737|M.leprae_Br4923 ---LGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKI
: * . .* .::: *. * : . : .
Mflv_0734|M.gilvum_PYR-GCK MRLFDGPDEVHMRTIARAELGREKSALATAACRVSHPGAAG---------
Mvan_0116|M.vanbaalenii_PYR-1 MRLFDGPDEVHMRTIARAELGREKSAMATAASRQSDTAASRQSNPAASRQ
MSMEG_0102|M.smegmatis_MC2_155 MRLFDGPDEVHMRTIARSELGREKSPLALAVTK-----------------
Mb0159c|M.bovis_AF2122/97 MRIFDGPDEVHLRSIARAELSREKSTFAAAVT------------------
Rv0154c|M.tuberculosis_H37Rv MRIFDGPDEVHLRSIARAELSREKSTFAAAVT------------------
MMAR_0374|M.marinum_M MRIFDGPDEVHMRSIARAELGREKSAFAAAVTSHG---------------
MAV_5144|M.avium_104 MRIFDGPDEVHMRTIARAELGREKSALAAAVTAHA---------------
TH_2913|M.thermoresistible__bu ARLYDGPDEVHKVTVARRTLREFEPRE--VPSEHIPTRRAAAREKFAHLL
MUL_4790|M.ulcerans_Agy99 LGIADGATELHKMTVARRTLRQYEPVATPFPSQHIPTRRAAAEARLAERL
MAB_0328|M.abscessus_ATCC_1997 FRLYDGPTEVHKYAIGRQVLRTPRA-------------------------
MLBr_00737|M.leprae_Br4923 TQIYEGTNQIQRVVMSRALLR-----------------------------
: :*. ::: :.* *
Mflv_0734|M.gilvum_PYR-GCK -------
Mvan_0116|M.vanbaalenii_PYR-1 SETAVTG
MSMEG_0102|M.smegmatis_MC2_155 -------
Mb0159c|M.bovis_AF2122/97 -------
Rv0154c|M.tuberculosis_H37Rv -------
MMAR_0374|M.marinum_M -------
MAV_5144|M.avium_104 -------
TH_2913|M.thermoresistible__bu AETAANS
MUL_4790|M.ulcerans_Agy99 EHSIAEF
MAB_0328|M.abscessus_ATCC_1997 -------
MLBr_00737|M.leprae_Br4923 -------