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LVRPRSEDELAFALRRSAGRTVRPIGSSHSFTQLCVTEDVQIDVSEMRRLISIDAQDRVRVQAGISLHEL NRTLLRHGLALPNLGDIDVQTLAGAAATGTHGTGLKFGNISQTILSMRIMTADGTIHELDDGDALRAARI SLGALGVVTEFTLQCVPAFRLHRSQSVHDLDTVLADLPTLLADTDHLELYLFPHTRRVLLLQSTRTDEAP WPRNPVKHWVERDLVENGALGALMWTAGRLPAAAPRISKLVAALASSNESQDESAAVFASPRKVKFTEME YSLPLTNAREAIETALATIERDRHQVAFPLEVRFTQADDALLAPAYGRESVYLAVHQTVHGSWESYFGGL EPILIGLGGRPHWGKRHTLTAQQLSERYPEWGTFQDIRARLDPGGTFSGGYLNRLLGPVSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0105c | - | - | 100% (412) | oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1407c | - | 1e-09 | 30.26% (195) | oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0192c | - | 2e-08 | 31.39% (137) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1800 | - | 3e-94 | 43.31% (411) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2230 | - | 1e-08 | 28.32% (173) | FAD linked oxidase domain-containing protein |
| M. tuberculosis H37Rv | Rv1771 | - | 3e-94 | 43.31% (411) | oxidoreductase |
| M. leprae Br4923 | MLBr_01103 | - | 5e-09 | 27.91% (172) | putative oxidoreductase subunit |
| M. marinum M | MMAR_2648 | - | 8e-94 | 42.96% (412) | oxidoreductase |
| M. avium 104 | MAV_1405 | - | 3e-09 | 29.65% (172) | oxidoreductase, FAD-binding |
| M. smegmatis MC2 155 | MSMEG_6382 | - | 2e-08 | 31.97% (122) | oxidoreductase, FAD-binding |
| M. thermoresistible (build 8) | TH_1603 | - | 5e-12 | 24.07% (403) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_3124 | - | 1e-92 | 42.48% (412) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5627 | - | 9e-12 | 22.98% (396) | FAD linked oxidase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2648|M.marinum_M -------------------------MKTVWRNWAGEQYCAPSEIVRPASE
MUL_3124|M.ulcerans_Agy99 -------------------------MKAVWRNWAREQYCAPSEIVRPASE
Mb1800|M.bovis_AF2122/97 -------------------------MSPIWSNWPGEQVCAPSAIVRPTSE
Rv1771|M.tuberculosis_H37Rv -------------------------MSPIWSNWPGEQVCAPSAIVRPTSE
MAB_0105c|M.abscessus_ATCC_199 ------------------------------------------MLVRPRSE
MSMEG_6382|M.smegmatis_MC2_155 ----------MGAVPSLTMSTTEFPTTTKRLMGWGRTAPTVASVLSTSDP
TH_1603|M.thermoresistible__bu ------------------MRTTEVETTPRRLTGWGRTAPTVAQVLSTSDA
Mvan_5627|M.vanbaalenii_PYR-1 ------------------MLSTEFPTTARRLTGWGRTAPSVARVLATPDP
MLBr_01103|M.leprae_Br4923 MG--VLTSLIAGLPDGMVVTDSAVTDGYRHDRALDPSAGKPLAVVQPRRT
MAV_1405|M.avium_104 MSSEALASLIADLPDGTVVTDPTVTEGYRQDRAFDPSAGKPLAVVRPRRT
Mflv_2230|M.gilvum_PYR-GCK MQ--PLASLIADLPDGTVVTDPDILESYRQDRAADPAAGTPLAVVRPRRT
:: .
MMAR_2648|M.marinum_M AELAELVAKAGQRG----ERVRAVGSGHSFTDCACTDG-VMVDMAGMQRI
MUL_3124|M.ulcerans_Agy99 AELAELVAKAGQRG----ERVRAVGSGHSFTDCACTDG-VMVDMAGMQRI
Mb1800|M.bovis_AF2122/97 AELADVIAQAAKRG----ERVRAVGSGHSFTDIACTDG-VMIDMTGLQRV
Rv1771|M.tuberculosis_H37Rv AELADVIAQAAKRG----ERVRAVGSGHSFTDIACTDG-VMIDMTGLQRV
MAB_0105c|M.abscessus_ATCC_199 DELAFALRRSAGR------TVRPIGSSHSFTQLCVTED-VQIDVSEMRRL
MSMEG_6382|M.smegmatis_MC2_155 EVIVRAVTRAAEE---GGRGVIARGLGRSYGDNAQNGGGLVIDMPALNRI
TH_1603|M.thermoresistible__bu EVIAEAVRRTAEQSKAGARGVIARGLGRSYGDNAQNGGGLVIDMTPLNRI
Mvan_5627|M.vanbaalenii_PYR-1 EVIVKAVARAAESGKGGGRGVIARGLGRSYGDNAQNGGGLVVDMSVLNRI
MLBr_01103|M.leprae_Br4923 DEVQTVLRWASANR----VPVVARGAGSGLSGGATALDDGIVLSTEKMRD
MAV_1405|M.avium_104 EEVQTVLRWASAHG----VPVVTRGAGSGLSGGATALDNGIVLSTEKMRD
Mflv_2230|M.gilvum_PYR-GCK EEVQTVLRWAGTHR----IAVVPRGMGTGLSGGATALDGGIVLSTEKMRD
: : :. * . * . . . . : . *
MMAR_2648|M.marinum_M VNVDPEAGLATVEGGAKLRPLFSQLAEHGLALE-NQGDIDKQSITGATAT
MUL_3124|M.ulcerans_Agy99 VNVDPEAGLATVEGGAKLRPLFSQLAEHGLALE-NQGDIDKQSITGATAT
Mb1800|M.bovis_AF2122/97 LDVDQPTGLVTVEGGAKLRALGPQLAQRRLGLE-NQGDVDPQSITGATAT
Rv1771|M.tuberculosis_H37Rv LDVDQPTGLVTVEGGAKLRALGPQLAQRRLGLE-NQGDVDPQSITGATAT
MAB_0105c|M.abscessus_ATCC_199 ISIDAQD-RVRVQAGISLHELNRTLLRHGLALP-NLGDIDVQTLAGAAAT
MSMEG_6382|M.smegmatis_MC2_155 HSIDSGTRLVDVDAGVSLDQLMKAALPHGLWVP-VLPGTRQVTVGGAIGC
TH_1603|M.thermoresistible__bu HRIDAETRLVDLDAGVSLDTLMKAALPFGLWVP-VLPGTRQVTVGGAIAC
Mvan_5627|M.vanbaalenii_PYR-1 HSMDSDSHLVDVDGGVNLDQLMRAALPLGLWVP-VLPGTRQVTVGGAIAC
MLBr_01103|M.leprae_Br4923 ITVDPVTRTAVCQPGLFNAEVKKAAAEHGLWYPPDPSSFEICSIGGNVAT
MAV_1405|M.avium_104 ITVDPVTRTAVCQPGLFNAEVKKAAAEHGLWYPPDPSSFEICSIGGNIAT
Mflv_2230|M.gilvum_PYR-GCK ITVDPVTRTAVVQPGLLNAEVKKVVAEHGLWYPPDPSSFEICSIGGNIAT
:* . : * : * . :: * .
MMAR_2648|M.marinum_M ATHGTGAR-FANVSAQIVALRLVTASGEVLELS----EGDDYLAARVSIG
MUL_3124|M.ulcerans_Agy99 ATHGTGAR-FANVAAQIVALRLVTASGEVLELS----EGDDYLAARVSIG
Mb1800|M.bovis_AF2122/97 ATHGTGVR-FQNLSARIVSLRLVTAGGEVLSLS----EGDDYLAARVSLG
Rv1771|M.tuberculosis_H37Rv ATHGTGVR-FQNLSARIVSLRLVTAGGEVLSLS----EGDDYLAARVSLG
MAB_0105c|M.abscessus_ATCC_199 GTHGTGLK-FGNISQTILSMRIMTADGTIHELD----DGDALRAARISLG
MSMEG_6382|M.smegmatis_MC2_155 DIHGKNHHSAGSFGNHVRSMELLTANGEVRHLTPAGPDSDLFWATVGGNG
TH_1603|M.thermoresistible__bu DIHGKNHHSAGSFGNHVRSIDLLTADGQIRRLTPDGDDPELFWATVGGNG
Mvan_5627|M.vanbaalenii_PYR-1 DIHGKNHHSAGSFGNHVRSMDLLTADGEVRTLTPSGPDADLFWATVGGNG
MLBr_01103|M.leprae_Br4923 NAGGLCCVKYGVTGDYVLGIQVVLADGTAVRLG----GPRLKDVAGLSLT
MAV_1405|M.avium_104 NAGGLCCVKYGVTTDYVLGMQVVLADGTAVRLG----GPRLKDVAGLSLT
Mflv_2230|M.gilvum_PYR-GCK NAGGLCCVKYGVTTDYVLGLQVVLADGTAVRLG----GPRLKDVAGLSLT
* : .: :: *.* * .: .
MMAR_2648|M.marinum_M ALGVISQLTLKVVP---LFTLHRDDELKPLAETLERLDEHVDNNDHFEFF
MUL_3124|M.ulcerans_Agy99 ALGVISQLTLKVVP---LFTLHRDDELKPLAETLERLDEHVDNNDHFEFF
Mb1800|M.bovis_AF2122/97 ALGVISQVTLQTVP---LFTLHRHDQRRSLAQTLERLDEFVDGNDHFEFF
Rv1771|M.tuberculosis_H37Rv ALGVISQVTLQTVP---LFTLHRHDQRRSLAQTLERLDEFVDGNDHFEFF
MAB_0105c|M.abscessus_ATCC_199 ALGVVTEFTLQCVP---AFRLHRSQSVHDLDTVLADLPTLLADTDHLELY
MSMEG_6382|M.smegmatis_MC2_155 LTGIILRATIEMTPTETAYFIADGDVTGSLDETIAFHSDGSEANYTYSSA
TH_1603|M.thermoresistible__bu LTGIILRATIEMTPTETAYFIADGDVTATLDETIALHSDGSEDNYTYSSA
Mvan_5627|M.vanbaalenii_PYR-1 LTGIILRATIEMTPTETAYFIADGDVTSGLEETIAFHSDGTEDNYTYSSA
MLBr_01103|M.leprae_Br4923 KLFVGSEGTLGIITEVTLRLLPTQNTSSIVVATFASVQAAVDAVLGVAAR
MAV_1405|M.avium_104 KLFVGSEGTLGVITEVTLRLVPKQNTSSVVVASFATVEDAVGAVLGVTGR
Mflv_2230|M.gilvum_PYR-GCK KLFVGSEGTLGVVTEVTLKLLPAQHPACTVVATFDSVESAADAVVEITGR
: . *: . : . : :
MMAR_2648|M.marinum_M VF------PYAETALTRTTRRSEEPPMPVPEWRRRVG-DQFENVGLGLVC
MUL_3124|M.ulcerans_Agy99 VF------PYAETALTRTTRRSEEPPMPVPEWRRRVG-DQFENVGLGLVC
Mb1800|M.bovis_AF2122/97 VF------PYADKALTRTMHRSDEQPKPTPGWQRMVG-ENFENGGLSLIC
Rv1771|M.tuberculosis_H37Rv VF------PYADKALTRTMHRSDEQPKPTPGWQRMVG-ENFENGGLSLIC
MAB_0105c|M.abscessus_ATCC_199 LF------PHTRRVLLLQSTRTDEAPWPRNPVKHWVERDLVENGALGALM
MSMEG_6382|M.smegmatis_MC2_155 WFDAISKPPKLGRAAISRGSLAKLDQLPSKLQKDPLKFDAPQLLTLPDIF
TH_1603|M.thermoresistible__bu WFDAISAPPKLGRAAISRGSLARLDELPPKLRKNPLKFDAPQLLTFPDIF
Mvan_5627|M.vanbaalenii_PYR-1 WFDAISAPPKLGRAVISRGSLATVDQLPRKLQKNPLKFDAPQYFTAPEIF
MLBr_01103|M.leprae_Br4923 LR------PAMLEFMDSVAINAVEDTFRMGLDR---EAAAMLVAGSDELG
MAV_1405|M.avium_104 LR------PSMLEFMDSVAINAVEDTLRMDLDR---GAAAMLVAGSDERG
Mflv_2230|M.gilvum_PYR-GCK IR------PSMLEFMDSTAINAVEDKLKMGLDR---DAAAMMVAASDDRG
* : :
MMAR_2648|M.marinum_M RTGRQFPSTAPKLNRLLTSLMSPSSVQDRGWKVYPSPRNVK---------
MUL_3124|M.ulcerans_Agy99 RTGRQFPSTAPKLNRLLTSLMSPSSVQDRGWKVYPSPRNVK---------
Mb1800|M.bovis_AF2122/97 QTGRRFPSVAPRLNRLMTNMMSSSTVQDRAYKVFATQRKVR---------
Rv1771|M.tuberculosis_H37Rv QTGRRFPSVAPRLNRLMTNMMSSSTVQDRAYKVFATQRKVR---------
MAB_0105c|M.abscessus_ATCC_199 WTAGRLPAAAPRISKLVAALASSNESQDESAAVFASPRKVK---------
MSMEG_6382|M.smegmatis_MC2_155 PNGLANKFTFMPIGELWYRKSGTYRNKVQNLTQFYHPLDMFGEWNRAYGS
TH_1603|M.thermoresistible__bu PNGLANKYTFGPIGELWYRKSGTYRNKIQNLTQFYHPLDMFGEWNRAYGP
Mvan_5627|M.vanbaalenii_PYR-1 PNGLGNKYTFGPMTEVWYRLGKTYRGKAQNLTQFYHPLDMVGDWNRAYGS
MLBr_01103|M.leprae_Br4923 HAGTDEAKLIGAVFAENGATQVSSTNDPDEGEAFVAARRFCIP-------
MAV_1405|M.avium_104 RAGSEDAEIMAKVFAENAATEVFSTDDPDEGEAFVVARRFCIP-------
Mflv_2230|M.gilvum_PYR-GCK AAGAQDAEYMARVFTEHGATEVFSTSDPDEGDAFVAARRFAIP-------
. : . : .
MMAR_2648|M.marinum_M --FTEMEYAIPRENAREAVRRVIEVVRRRDLPIMYP--LEVRFSAPDDAF
MUL_3124|M.ulcerans_Agy99 --FTEMEYAIPRENAREAVRRVIEVVRRRDLPIMYP--LEVRFSAPDDAF
Mb1800|M.bovis_AF2122/97 --FTEMEYAIPRENGREALQRVIDLVRRRSLPIMFP--IEVRFSAPDDSF
Rv1771|M.tuberculosis_H37Rv --FTEMEYAIPRENGREALQRVIDLVRRRSLPIMFP--IEVRFSAPDDSF
MAB_0105c|M.abscessus_ATCC_199 --FTEMEYSLPLTNAREAIETALATIERDRHQVAFP--LEVRFTQADDAL
MSMEG_6382|M.smegmatis_MC2_155 AGFLQYQFVVP-TEAVEEFKSIIVDIQRSGHYSFLN--VFKLFGPGNQAP
TH_1603|M.thermoresistible__bu AGFTQYQFVVP-TEAVDEFKAILVDIQRSGHYSFLN--VFKLFGPGNKAP
Mvan_5627|M.vanbaalenii_PYR-1 VGFAQYQFVVP-TEAVDEFKRIMYDIQRSGHYSFLN--VFKLFGPGNDAP
MLBr_01103|M.leprae_Br4923 --AVESKGSLLLEDVGVPLPALGKLVTGIAHISTERNLMISVIAHAGDGN
MAV_1405|M.avium_104 --AVEAKGSLLLEDVGVPLPALGRLVTGIAAIAAERDLMISVIAHAGDGN
Mflv_2230|M.gilvum_PYR-GCK --AVESKGSLLLEDVGVPLPALAELVGGVEKIAAARDVMISVIAHAGDGN
: : : : . : : : ...
MMAR_2648|M.marinum_M LSTAYERDTCYIAVHQYTGMEFETYFRAVEAIMDEYGGRPHWGKRHYQRA
MUL_3124|M.ulcerans_Agy99 LSTAYERDTCYIAVHQYTGMEFETYFRAVEAIMDEYRGRPHWGKRHYQRA
Mb1800|M.bovis_AF2122/97 LSTAYGRDTCYIAVHQYAGMEFESYFRAVEEIMDDYAGRPHWGKRHYQTA
Rv1771|M.tuberculosis_H37Rv LSTAYGRDTCYIAVHQYAGMEFESYFRAVEEIMDDYAGRPHWGKRHYQTA
MAB_0105c|M.abscessus_ATCC_199 LAPAYGRESVYLAVHQTVHGSWESYFGGLEPILIGLGGRPHWGKRHTLTA
MSMEG_6382|M.smegmatis_MC2_155 LS--FPIPGWNVCVDFPIKAGLHEFVTELDRRVLEFGGRLYTAKDSRTTA
TH_1603|M.thermoresistible__bu LS--FPIPGWNVCVDFPVKPGLNEFLTGLDRRVLEFGGRLYTAKDSRTTA
Mvan_5627|M.vanbaalenii_PYR-1 LS--FPIPGWNVCVDFQINPGLNEFLNGLDKRVLEFGGRLYTAKDSRTTA
MLBr_01103|M.leprae_Br4923 THPLIVYNPADATMTERAHRAFGEIMDMAVGLGGTITGEHGVGRLKRPWL
MAV_1405|M.avium_104 THPLIVYDPADADMTERAHLAFGEIMDLAVGLGGTITGEHGVGRLKRPWL
Mflv_2230|M.gilvum_PYR-GCK THPLIVFDPSDTAMEQRAQQAFGEIMDLAVSLGGTITGEHGVGRLKRPWL
: . *. .:
MMAR_2648|M.marinum_M ASLRERYPAWDRFTAVRDRLDPNRVFLNDYTRRVLGA---
MUL_3124|M.ulcerans_Agy99 ASLRERYPAWDRFTAVRDRLDPNRVFLNDYTRRVLGA---
Mb1800|M.bovis_AF2122/97 ATLRERYPQWDRFAAVRDRLDPDRVFLNDYTRRVLGP---
Rv1771|M.tuberculosis_H37Rv ATLRERYPQWDRFAAVRDRLDPDRVFLNDYTRRVLGP---
MAB_0105c|M.abscessus_ATCC_199 QQLSERYPEWGTFQDIRARLDPGGTFSGGYLNRLLGPVSP
MSMEG_6382|M.smegmatis_MC2_155 ETFHAMYPRIDEWIRIRRSVDPDGVFASDMARRLQLL---
TH_1603|M.thermoresistible__bu ETFHAMYPRIDEWIAVRRRVDPEGIFASDMARRLELL---
Mvan_5627|M.vanbaalenii_PYR-1 ETFHAMYPRIDEWIALRRKVDPDGVFASDMARRLELL---
MLBr_01103|M.leprae_Br4923 DDYLG-PDVMELNQRIKHALDPYGILNPGAAI--------
MAV_1405|M.avium_104 AGYLG-PEVMDLNRRIKQALDPQGILNPGSGI--------
Mflv_2230|M.gilvum_PYR-GCK AGQLG-PEAMELNRRIKQALDPDGILNPGAAI--------
:: :** : .