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M. thermoresistible (build 8) TH_4610 (-)

annotation: geranylgeranyl reductase
coordinates: 3072911 - 3073177
length: 89

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4610--100% (89)geranylgeranyl reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4291-5e-3482.05% (78) geranylgeranyl reductase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3406-4e-2563.64% (77) geranylgeranyl reductase
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_2308-2e-3685.00% (80) geranylgeranyl reductase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2055-5e-3582.05% (78) geranylgeranyl reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4291|M.gilvum_PYR-GCK          -MTQRYDVVIAGGGPSGSAAAWQAAQTGAKVVVLDKAQFPRAKPCGDGLT
Mvan_2055|M.vanbaalenii_PYR-1       -MTQRYDVVIAGGGPSGSAAAWQAAQTGAKVVVLDKAQFPRAKPCGDGLT
MSMEG_2308|M.smegmatis_MC2_155      -MTQRYDLVIAGGGPSGSAAAWQAAQTGAKVVVLDKAEFPRDKPCGDGLT
TH_4610|M.thermoresistible__bu      --------------------------------------------------
MAB_3406|M.abscessus_ATCC_1997      MSEKHYDIAVVGGGPAGSSAAWQAARTGARVVLVDKAEFPRDKPCGDGLT
                                                                                      

Mflv_4291|M.gilvum_PYR-GCK          ARAVSYLQKMGLADEVATYHRVNRVTVFSPSRWELSFPKRPGMPDHGHTV
Mvan_2055|M.vanbaalenii_PYR-1       ARAVSYLQKMGLADEVATYHRVNRVTVFSPSRWELSFPKRPGMPDHGHTV
MSMEG_2308|M.smegmatis_MC2_155      ARAVSYLQKMGLADEVATYHRVNRVTVFSPSEWELSFPRRPGMPDHGHTV
TH_4610|M.thermoresistible__bu      --------------------------------------------------
MAB_3406|M.abscessus_ATCC_1997      ARAVSYLQKMGLAQEVAQFHRVDGVRVDSGSIWELTFPKRPGMPDHGHVV
                                                                                      

Mflv_4291|M.gilvum_PYR-GCK          SREHLDTVLLKHAESAGAEIRQGAEVAGPEFD---ASGRVVGVILKSGEK
Mvan_2055|M.vanbaalenii_PYR-1       SREHLDTVLLKHAESAGAEVRQGAEVAGPEFD---ASGRVIGVVLKGGEK
MSMEG_2308|M.smegmatis_MC2_155      SRTHLDTVLLKHAESAGAEVRQGAEVAGPEFD---ANGRVIGVVLKSGEK
TH_4610|M.thermoresistible__bu      --------------------------------------------------
MAB_3406|M.abscessus_ATCC_1997      RRPELDTLLLKHAESAGVEVRQSTEAVGPVGDGDLVKGVEVKTANGSRET
                                                                                      

Mflv_4291|M.gilvum_PYR-GCK          VLGDAVIAADGAYSPIKRALKIDSEYNGYSAIAIRSEMPANRPDTDSLDI
Mvan_2055|M.vanbaalenii_PYR-1       VYGDAVIAADGAYSPIKRALKIDSEYNGYSAIAIRSEMPANRPDTDSLDI
MSMEG_2308|M.smegmatis_MC2_155      VYGDAVIAADGAYSPIKRALKIDSEYNGYSAIAIRSEMHANRPDSDSLDI
TH_4610|M.thermoresistible__bu      --------------------------------------------------
MAB_3406|M.abscessus_ATCC_1997      ISADAVIVADGAYSPFKRAMNIDSEYKGYSAIAIRAEMTANREDSNMLDI
                                                                                      

Mflv_4291|M.gilvum_PYR-GCK          YLKLLFEGDQLPGYGWVFPMGDGIFNIGLGYVNSYKNWQSINATQFLGEF
Mvan_2055|M.vanbaalenii_PYR-1       YLKLLFQGDQLPGYGWVFPMGNGIFNIGLGYVNSYKNWQSINATQFLGDF
MSMEG_2308|M.smegmatis_MC2_155      YLKLVFQGDQLPGYGWVFPMGNGMFNIGLGYVNSYKNWQSINATQFLGEF
TH_4610|M.thermoresistible__bu      --------------------------------------------------
MAB_3406|M.abscessus_ATCC_1997      DLRIHHKQDALPGYGWVFPLGGGRINIGIGYVNSYRRWQDVNAAQVLDTY
                                                                                      

Mflv_4291|M.gilvum_PYR-GCK          LRTLPREWELPPIEELKKNKSVRAWRLPMGFTAWPPWRPGVLFTGDSLGA
Mvan_2055|M.vanbaalenii_PYR-1       LRTLPREWDLPPIEELKKNKSVRAWRLPMGFTAWPPWRPGVLFTGDSLGA
MSMEG_2308|M.smegmatis_MC2_155      LRSLPREWELPPIEELKKNKSVRAWRLPMGFTAWPPWRPGVLFTGDSLGA
TH_4610|M.thermoresistible__bu      ------------------------------------------MATATLXX
MAB_3406|M.abscessus_ATCC_1997      MNKLPKEWELPNLAELRKNKGVRAWRLPMGFTAWPPWRPGVLFAGDSLGA
                                                                              ::  :*  

Mflv_4291|M.gilvum_PYR-GCK          GKPASGAGISKALESGLAAGECAVAALTNGGPDDFTNYALRMEAAWGREY
Mvan_2055|M.vanbaalenii_PYR-1       GKPASGAGISKALESGLAAGECAVAALMNGGPDDFTNYAQRMEAAWGREY
MSMEG_2308|M.smegmatis_MC2_155      GKPASGAGISKALESGLAAGECAIAALQNGGPDDFTNYAQRMEAAWGREY
TH_4610|M.thermoresistible__bu      -----------------XAGECAIAALLNGGPDDFTNYAQRMEAAWGKEY
MAB_3406|M.abscessus_ATCC_1997      GKPASGAGISKALESGLAAGECAVAALQNAGPQDFINYEQRMNEAWGKEY
                                                      *****:*** *.**:** **  **: ***:**

Mflv_4291|M.gilvum_PYR-GCK          RRGRIMHKLIGQPKLAEAGVKLIDNAAFRDRMLKALYKKAQGPQHSF--
Mvan_2055|M.vanbaalenii_PYR-1       RRGRYMHKLIGQPRLAAAGVKLIDNAAFRDRMLKALYKKAQGPQHSF--
MSMEG_2308|M.smegmatis_MC2_155      RRGRYMHKLIGKPKLAEAGVKLIDNAAFRDRMLKALYKKAQGPQHVIKK
TH_4610|M.thermoresistible__bu      RRGRYMHKLIGYPKIAEAGVRLIDNRAFRDRMLRALYKKH-GPRHTVK-
MAB_3406|M.abscessus_ATCC_1997      KRGRLMHRAIGNPWLCAQGIKLIDNDLFRDRMLKVLYKRAQGPGHKTSH
                                    :*** **: ** * :.  *::****  ******:.***:  ** *