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M. thermoresistible (build 8) TH_4423 (-)

annotation: conserved hypothetical protein
coordinates: 1240999 - 1241631
length: 211

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4423--100% (211)conserved hypothetical protein
M. thermoresistible (build 8)TH_1304-2e-1233.08% (130) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_3953-3e-0530.50% (141) PUTATIVE conserved hypothetical protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0318c-1e-1334.11% (129) hypothetical protein Mb0318c
M. gilvum PYR-GCKMflv_4177-6e-5763.80% (163) hypothetical protein Mflv_4177
M. tuberculosis H37RvRv0310c-1e-1334.11% (129) hypothetical protein Rv0310c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2629-2e-1237.93% (145) hypothetical protein MAB_2629
M. marinum MMMAR_4720-2e-5763.41% (164) hypothetical protein MMAR_4720
M. avium 104MAV_2498-6e-5961.96% (163) hypothetical protein MAV_2498
M. smegmatis MC2 155MSMEG_2245-8e-2949.29% (140) bile-acid 7-alpha dehydratase
M. ulcerans Agy99MUL_0320-4e-5562.20% (164) hypothetical protein MUL_0320
M. vanbaalenii PYR-1Mvan_2186-3e-5664.63% (164) hypothetical protein Mvan_2186

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4177|M.gilvum_PYR-GCK          ----------------------MTD------------------AAVTVLE
Mvan_2186|M.vanbaalenii_PYR-1       -----------------------MD------------------DAAALVE
MMAR_4720|M.marinum_M               ----------------------MLD------------------AATTLWE
MUL_0320|M.ulcerans_Agy99           ----------------------MLD------------------AATTLWE
MAV_2498|M.avium_104                ----------------------MTERA-------------HSAVADTLPA
TH_4423|M.thermoresistible__bu      VLADTKGPAVVVPAFLAPGYHVNTDXXXPTAGVTLVRVSGQREPAERLVE
MSMEG_2245|M.smegmatis_MC2_155      ----------------------MSD------------------------D
Mb0318c|M.bovis_AF2122/97           ----------------------MCCNG--------------VVTPGDPAD
Rv0310c|M.tuberculosis_H37Rv        ----------------------MCCNG--------------VVTPGDPAD
MAB_2629|M.abscessus_ATCC_1997      ----------------------MPRP-----------------TAETLVD
                                                                                      

Mflv_4177|M.gilvum_PYR-GCK          IEAIKTLKARYCRYLDTKDWESWRTLFSDDFRS--DTSRAGG-------K
Mvan_2186|M.vanbaalenii_PYR-1       IEAIKQLKARYSRFLDTKDWDSWRSLFADDFHS--DTAGAGG-------K
MMAR_4720|M.marinum_M               IEAIKQLKARYCRYLDTKRWDDWRTLFTDDFLS--DTSRCGG-------K
MUL_0320|M.ulcerans_Agy99           IEAIKQLKARYCRYLDTKRWDDWRTLFTDDFLS--DTSRCGG-------K
MAV_2498|M.avium_104                IESIKQLKARYCRYLDTKDWAAWRTIFTDDFLS--DTSEAGG-------A
TH_4423|M.thermoresistible__bu      LEEIKRLKARYCRHLDAKDWAAWRTLFTDDFVS--DTASAGG-------T
MSMEG_2245|M.smegmatis_MC2_155      LEAIKRLKARYCRLLDTKDIEAWRTLFADDVVVTLDMAVSTGGADPQTAP
Mb0318c|M.bovis_AF2122/97           IAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSV-GTELH-----
Rv0310c|M.tuberculosis_H37Rv        IAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSV-GTELH-----
MAB_2629|M.abscessus_ATCC_1997      IHEITELKYRYARTLDNKLWDEFADTLTEDVQATYGTAVHGAPLE-----
                                    :  *. ** ** * ** *    :   :::*.    . :            

Mflv_4177|M.gilvum_PYR-GCK          VIVGADDFVAFTRRSLR--TNATVHQVHAPEITLTSPTTADGIWALEDVV
Mvan_2186|M.vanbaalenii_PYR-1       VIDGADEFVAFTRRSLG--DRATVHQVHAPEIELTSPTTATAVWALEDVV
MMAR_4720|M.marinum_M               VIHGADEFVAYVRATLGRPSRPTVHQVHAPEITLSSPTTATGVWALQDVV
MUL_0320|M.ulcerans_Agy99           VIHGADEFVAYVRATLGRPSRPTVHQVHAPEITLSSPTTATGVWALQDVV
MAV_2498|M.avium_104                VIAGADDFVAFTRRALGRATQPTAHQVHNPEIELTSATTARGTWALQDVV
TH_4423|M.thermoresistible__bu      TIQGADEFVAFVRRNLGNPAKVTSHQVHAPEIELTSPTTARGVWALEDVV
MSMEG_2245|M.smegmatis_MC2_155      PLHGFDEFLPVVWGGVE--HAATVHHCHTPEIDLTSGTTASGIWAMEDML
Mb0318c|M.bovis_AF2122/97           -FTNRADLVDYLRQALG-PGVITEHRVTHPEITVTG-DTATGIWYLQDRV
Rv0310c|M.tuberculosis_H37Rv        -FTNRADLVDYLRQALG-PGVITEHRVTHPEITVTG-DTATGIWYLQDRV
MAB_2629|M.abscessus_ATCC_1997      -FTSRAAVVEYMRTSLT-TDITSVHTMSHPEINVTG-DTATGSWAMSDVV
                                     : .   .:      :      : *    *** ::.  ** . * :.* :

Mflv_4177|M.gilvum_PYR-GCK          RLAPG-LNLRGYGHYTESYEK-LDGRWLITESTLTRLREDIFNVAVSVYV
Mvan_2186|M.vanbaalenii_PYR-1       RLAPG-VNLRGYGHYTESYAK-VDGYWLITASTLTRLREDVFNIAVSVYV
MMAR_4720|M.marinum_M               RLGPG-VNLDGRGHYHETYEK-LDGAWLIKSSTLTRLREDVFNPLFSVPI
MUL_0320|M.ulcerans_Agy99           RLGPG-VNLDGRGHYHETYEK-LDGARLIKSSTLTRLREDVFNPPFSVPI
MAV_2498|M.avium_104                RFGPG-ITLVGYGHYHETYEN-IDGQWFIKSSKLTRLREDIVTPLFSIYV
TH_4423|M.thermoresistible__bu      RLGPA-VHMRGYGHYHETYRK-VDGRWLIASSRLTRLRTDFFNGLFSVYL
MSMEG_2245|M.smegmatis_MC2_155      FFPDG-SELHGAGHYHETYEK-RDSTWVITSLHLTRT-------LLKFKA
Mb0318c|M.bovis_AF2122/97           IVAEFNFMLIGAAFYHDQYRRTTDG-WRISATGYDRTYEATMSLAGLNFN
Rv0310c|M.tuberculosis_H37Rv        IVAEFNFMLIGAAFYHDQYRRTTDG-WRISATGYDRTYEATMSLAGLNFN
MAB_2629|M.abscessus_ATCC_1997      IVPGHNVLITGTSYYTDRYRRDSDGSWRISHISYYRLYEAMQNTKDIGFH
                                     .      : * ..* : * .  *.   *      *              

Mflv_4177|M.gilvum_PYR-GCK          SPRMKRAIGALARRVAH----
Mvan_2186|M.vanbaalenii_PYR-1       SDRIKRVVGRLGRRLVR----
MMAR_4720|M.marinum_M               SPRLRDAAAALLHRLGR----
MUL_0320|M.ulcerans_Agy99           SPRLRDAAAALLHRLGR----
MAV_2498|M.avium_104                SPRIRAAIGTIAGRLMDR---
TH_4423|M.thermoresistible__bu      SPRTERILSSVATKVARRFTR
MSMEG_2245|M.smegmatis_MC2_155      AQRDT----------------
Mb0318c|M.bovis_AF2122/97           IRPGRALAD------------
Rv0310c|M.tuberculosis_H37Rv        IRPGRALAD------------
MAB_2629|M.abscessus_ATCC_1997      LIANRWSQ-------------