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DDAAALVEIEAIKQLKARYSRFLDTKDWDSWRSLFADDFHSDTAGAGGKVIDGADEFVAFTRRSLGDRAT VHQVHAPEIELTSPTTATAVWALEDVVRLAPGVNLRGYGHYTESYAKVDGYWLITASTLTRLREDVFNIA VSVYVSDRIKRVVGRLGRRLVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2186 | - | - | 100% (163) | hypothetical protein Mvan_2186 |
| M. vanbaalenii PYR-1 | Mvan_0432 | - | 6e-12 | 38.46% (130) | hypothetical protein Mvan_0432 |
| M. vanbaalenii PYR-1 | Mvan_2225 | - | 5e-08 | 44.07% (59) | hypothetical protein Mvan_2225 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0318c | - | 4e-14 | 35.77% (137) | hypothetical protein Mb0318c |
| M. gilvum PYR-GCK | Mflv_4177 | - | 1e-69 | 76.88% (160) | hypothetical protein Mflv_4177 |
| M. tuberculosis H37Rv | Rv0310c | - | 4e-14 | 35.77% (137) | hypothetical protein Rv0310c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2629 | - | 1e-14 | 39.46% (147) | hypothetical protein MAB_2629 |
| M. marinum M | MMAR_4720 | - | 3e-57 | 67.27% (165) | hypothetical protein MMAR_4720 |
| M. avium 104 | MAV_2498 | - | 7e-53 | 60.87% (161) | hypothetical protein MAV_2498 |
| M. smegmatis MC2 155 | MSMEG_2245 | - | 6e-28 | 47.37% (133) | bile-acid 7-alpha dehydratase |
| M. thermoresistible (build 8) | TH_4423 | - | 1e-56 | 64.63% (164) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0320 | - | 7e-56 | 66.67% (165) | hypothetical protein MUL_0320 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2186|M.vanbaalenii_PYR-1 -----------------------MD------------------DAAALVE
Mflv_4177|M.gilvum_PYR-GCK ----------------------MTD------------------AAVTVLE
MMAR_4720|M.marinum_M ----------------------MLD------------------AATTLWE
MUL_0320|M.ulcerans_Agy99 ----------------------MLD------------------AATTLWE
MAV_2498|M.avium_104 ----------------------MTERA-------------HSAVADTLPA
TH_4423|M.thermoresistible__bu VLADTKGPAVVVPAFLAPGYHVNTDXXXPTAGVTLVRVSGQREPAERLVE
MSMEG_2245|M.smegmatis_MC2_155 ----------------------MSD------------------------D
Mb0318c|M.bovis_AF2122/97 ----------------------MCCNG--------------VVTPGDPAD
Rv0310c|M.tuberculosis_H37Rv ----------------------MCCNG--------------VVTPGDPAD
MAB_2629|M.abscessus_ATCC_1997 ----------------------MPRP-----------------TAETLVD
Mvan_2186|M.vanbaalenii_PYR-1 IEAIKQLKARYSRFLDTKDWDSWRSLFADDFHS--DTAGAGG-------K
Mflv_4177|M.gilvum_PYR-GCK IEAIKTLKARYCRYLDTKDWESWRTLFSDDFRS--DTSRAGG-------K
MMAR_4720|M.marinum_M IEAIKQLKARYCRYLDTKRWDDWRTLFTDDFLS--DTSRCGG-------K
MUL_0320|M.ulcerans_Agy99 IEAIKQLKARYCRYLDTKRWDDWRTLFTDDFLS--DTSRCGG-------K
MAV_2498|M.avium_104 IESIKQLKARYCRYLDTKDWAAWRTIFTDDFLS--DTSEAGG-------A
TH_4423|M.thermoresistible__bu LEEIKRLKARYCRHLDAKDWAAWRTLFTDDFVS--DTASAGG-------T
MSMEG_2245|M.smegmatis_MC2_155 LEAIKRLKARYCRLLDTKDIEAWRTLFADDVVVTLDMAVSTGGADPQTAP
Mb0318c|M.bovis_AF2122/97 IAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSV-GTELH-----
Rv0310c|M.tuberculosis_H37Rv IAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSV-GTELH-----
MAB_2629|M.abscessus_ATCC_1997 IHEITELKYRYARTLDNKLWDEFADTLTEDVQATYGTAVHGAPLE-----
: *. ** ** * ** * : :::*. . :
Mvan_2186|M.vanbaalenii_PYR-1 VIDGADEFVAFTRRSLG--DRATVHQVHAPEIELTSPTTATAVWALEDVV
Mflv_4177|M.gilvum_PYR-GCK VIVGADDFVAFTRRSLR--TNATVHQVHAPEITLTSPTTADGIWALEDVV
MMAR_4720|M.marinum_M VIHGADEFVAYVRATLGRPSRPTVHQVHAPEITLSSPTTATGVWALQDVV
MUL_0320|M.ulcerans_Agy99 VIHGADEFVAYVRATLGRPSRPTVHQVHAPEITLSSPTTATGVWALQDVV
MAV_2498|M.avium_104 VIAGADDFVAFTRRALGRATQPTAHQVHNPEIELTSATTARGTWALQDVV
TH_4423|M.thermoresistible__bu TIQGADEFVAFVRRNLGNPAKVTSHQVHAPEIELTSPTTARGVWALEDVV
MSMEG_2245|M.smegmatis_MC2_155 PLHGFDEFLPVVWGGVE--HAATVHHCHTPEIDLTSGTTASGIWAMEDML
Mb0318c|M.bovis_AF2122/97 -FTNRADLVDYLRQALG-PGVITEHRVTHPEITVTG-DTATGIWYLQDRV
Rv0310c|M.tuberculosis_H37Rv -FTNRADLVDYLRQALG-PGVITEHRVTHPEITVTG-DTATGIWYLQDRV
MAB_2629|M.abscessus_ATCC_1997 -FTSRAAVVEYMRTSLT-TDITSVHTMSHPEINVTG-DTATGSWAMSDVV
: . .: : : * *** ::. ** . * :.* :
Mvan_2186|M.vanbaalenii_PYR-1 RLAPG-VNLRGYGHYTESYAK-VDGYWLITASTLTRLREDVFNIAVSVYV
Mflv_4177|M.gilvum_PYR-GCK RLAPG-LNLRGYGHYTESYEK-LDGRWLITESTLTRLREDIFNVAVSVYV
MMAR_4720|M.marinum_M RLGPG-VNLDGRGHYHETYEK-LDGAWLIKSSTLTRLREDVFNPLFSVPI
MUL_0320|M.ulcerans_Agy99 RLGPG-VNLDGRGHYHETYEK-LDGARLIKSSTLTRLREDVFNPPFSVPI
MAV_2498|M.avium_104 RFGPG-ITLVGYGHYHETYEN-IDGQWFIKSSKLTRLREDIVTPLFSIYV
TH_4423|M.thermoresistible__bu RLGPA-VHMRGYGHYHETYRK-VDGRWLIASSRLTRLRTDFFNGLFSVYL
MSMEG_2245|M.smegmatis_MC2_155 FFPDG-SELHGAGHYHETYEK-RDSTWVITSLHLTRT-------LLKFKA
Mb0318c|M.bovis_AF2122/97 IVAEFNFMLIGAAFYHDQYRRTTDG-WRISATGYDRTYEATMSLAGLNFN
Rv0310c|M.tuberculosis_H37Rv IVAEFNFMLIGAAFYHDQYRRTTDG-WRISATGYDRTYEATMSLAGLNFN
MAB_2629|M.abscessus_ATCC_1997 IVPGHNVLITGTSYYTDRYRRDSDGSWRISHISYYRLYEAMQNTKDIGFH
. : * ..* : * . *. * *
Mvan_2186|M.vanbaalenii_PYR-1 SDRIKRVVGRLGRRLVR----
Mflv_4177|M.gilvum_PYR-GCK SPRMKRAIGALARRVAH----
MMAR_4720|M.marinum_M SPRLRDAAAALLHRLGR----
MUL_0320|M.ulcerans_Agy99 SPRLRDAAAALLHRLGR----
MAV_2498|M.avium_104 SPRIRAAIGTIAGRLMDR---
TH_4423|M.thermoresistible__bu SPRTERILSSVATKVARRFTR
MSMEG_2245|M.smegmatis_MC2_155 AQRDT----------------
Mb0318c|M.bovis_AF2122/97 IRPGRALAD------------
Rv0310c|M.tuberculosis_H37Rv IRPGRALAD------------
MAB_2629|M.abscessus_ATCC_1997 LIANRWSQ-------------