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M. thermoresistible (build 8) TH_4394 (-)

annotation: translation elongation factor 1A (EF-1A/EF-Tu)
coordinates: 3692979 - 3694169
length: 397

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4394--100% (397)translation elongation factor 1A (EF-1A/EF-Tu)
M. thermoresistible (build 8)TH_2244cysN5e-2127.60% (279) PROBABLE BIFUNCTIONAL ENZYME CYSN/CYSC: SULFATE
M. thermoresistible (build 8)TH_1877typA9e-1827.85% (298) GTP-binding protein TypA/BipA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0704tuf0.092.17% (396) elongation factor Tu
M. gilvum PYR-GCKMflv_5075-0.093.43% (396) elongation factor Tu
M. tuberculosis H37RvRv0685tuf0.092.17% (396) elongation factor Tu
M. leprae Br4923MLBr_01877tuf0.091.92% (396) elongation factor Tu
M. abscessus ATCC 19977MAB_3848c-0.091.18% (397) elongation factor Tu
M. marinum MMMAR_1014tuf0.092.93% (396) iron-regulated elongation factor EF-Tu, Tuf
M. avium 104MAV_4489tuf0.093.69% (396) elongation factor Tu
M. smegmatis MC2 155MSMEG_1401tuf0.093.94% (396) elongation factor Tu
M. ulcerans Agy99MUL_0766tuf0.092.93% (396) elongation factor Tu
M. vanbaalenii PYR-1Mvan_1282-0.094.19% (396) elongation factor Tu

CLUSTAL 2.0.9 multiple sequence alignment


Mb0704|M.bovis_AF2122/97            MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPDLNETKAFD
Rv0685|M.tuberculosis_H37Rv         MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPDLNETKAFD
MAV_4489|M.avium_104                MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPDLNESRAFD
MMAR_1014|M.marinum_M               MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNESRAFD
MUL_0766|M.ulcerans_Agy99           MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNESRAFD
MLBr_01877|M.leprae_Br4923          MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPNLNESRAFD
MSMEG_1401|M.smegmatis_MC2_155      MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPDLNESRAFD
Mflv_5075|M.gilvum_PYR-GCK          MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDQYPDLNESRAFD
Mvan_1282|M.vanbaalenii_PYR-1       MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPDLNESRAFD
TH_4394|M.thermoresistible__bu      VAKAKFERTKPHVNIGTIGHVDHGKTTTTAAITKVLHDKYPELNESRAFE
MAB_3848c|M.abscessus_ATCC_199      MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPDLNEASAFD
                                    :*****:******************** **********::*:***: **:

Mb0704|M.bovis_AF2122/97            QIDNAPEERQRGITINIAHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
Rv0685|M.tuberculosis_H37Rv         QIDNAPEERQRGITINIAHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
MAV_4489|M.avium_104                QIDNAPEERQRGITINISHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
MMAR_1014|M.marinum_M               QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
MUL_0766|M.ulcerans_Agy99           QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
MLBr_01877|M.leprae_Br4923          QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
MSMEG_1401|M.smegmatis_MC2_155      QIDNAPEERQRGITINISHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
Mflv_5075|M.gilvum_PYR-GCK          QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
Mvan_1282|M.vanbaalenii_PYR-1       QIDNAPEERQRGITINISHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
TH_4394|M.thermoresistible__bu      QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
MAB_3848c|M.abscessus_ATCC_199      QIDNAPEEKARGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
                                    ********: *******:******:*************************

Mb0704|M.bovis_AF2122/97            MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADAVDDEELLE
Rv0685|M.tuberculosis_H37Rv         MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADAVDDEELLE
MAV_4489|M.avium_104                MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEELLE
MMAR_1014|M.marinum_M               MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLE
MUL_0766|M.ulcerans_Agy99           MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLE
MLBr_01877|M.leprae_Br4923          MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLE
MSMEG_1401|M.smegmatis_MC2_155      MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELIE
Mflv_5075|M.gilvum_PYR-GCK          MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEELIE
Mvan_1282|M.vanbaalenii_PYR-1       MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEELIE
TH_4394|M.thermoresistible__bu      MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDPELLE
MAB_3848c|M.abscessus_ATCC_199      MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDMVDDEELLE
                                    ***************************************:* *** **:*

Mb0704|M.bovis_AF2122/97            LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDAKWVASVEELMNAVDE
Rv0685|M.tuberculosis_H37Rv         LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDAKWVASVEELMNAVDE
MAV_4489|M.avium_104                LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDAKWVESVEQLMEAVDE
MMAR_1014|M.marinum_M               LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDPKWVESVEQLMDAVDE
MUL_0766|M.ulcerans_Agy99           LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDPKWVESVEQLMDAVDE
MLBr_01877|M.leprae_Br4923          LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDAKWVESVTQLMDAVDE
MSMEG_1401|M.smegmatis_MC2_155      LVEMEVRELLAAQDFD-EEAPVVRVSALKALEGDPKWVKSVEELMEAVDA
Mflv_5075|M.gilvum_PYR-GCK          LVEMEVRELLAAQDFD-EDAPVVKVSALKALEGDEKWVKSVQELMAAVDE
Mvan_1282|M.vanbaalenii_PYR-1       LVEMEVRELLAAQDFD-EEAPVVKVSALKALEGDEKWVKSVEELMEAVDE
TH_4394|M.thermoresistible__bu      LVEMEVRELLASQEFD-ENAPVIPISALKALEGDPKWVKSVEDLMEAVDE
MAB_3848c|M.abscessus_ATCC_199      LVEMEVRELLSSQDFDGDNAPVVRVSALKALEGDAEWGKTVADLMDAVDE
                                    **********::*:** ::***: :********* :*  :* :** *** 

Mb0704|M.bovis_AF2122/97            SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
Rv0685|M.tuberculosis_H37Rv         SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
MAV_4489|M.avium_104                SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
MMAR_1014|M.marinum_M               SIPDPVRETDRPFLMPVEDVFTITGRGTVVTGRVERGIINVNEEVEIVGI
MUL_0766|M.ulcerans_Agy99           SIPDPVRETDRPFLMPVEDVFTITGRGTVVTGRVERGIINVNEEVEIVGI
MLBr_01877|M.leprae_Br4923          SIPAPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVVNVNEEVEIVGI
MSMEG_1401|M.smegmatis_MC2_155      SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
Mflv_5075|M.gilvum_PYR-GCK          SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
Mvan_1282|M.vanbaalenii_PYR-1       SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGIINVNEEVEIVGI
TH_4394|M.thermoresistible__bu      SIPDPVRDTDKPFLMPIEDVFTITGRGTVVTGRIERGVINVNDEVEIVGI
MAB_3848c|M.abscessus_ATCC_199      SIPDPVRETEKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEDVEIVGI
                                    *** ***:*::*****:****************:***::***::******

Mb0704|M.bovis_AF2122/97            RPSTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGVKREDVERGQVVTKPG
Rv0685|M.tuberculosis_H37Rv         RPSTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGVKREDVERGQVVTKPG
MAV_4489|M.avium_104                RPSSTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVTKPG
MMAR_1014|M.marinum_M               RPTSTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPG
MUL_0766|M.ulcerans_Agy99           RPTSTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPG
MLBr_01877|M.leprae_Br4923          RQTTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVIKPG
MSMEG_1401|M.smegmatis_MC2_155      RPETTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPG
Mflv_5075|M.gilvum_PYR-GCK          RPTVTKTTVTGVEMFRKLLDQGQAGDNVGLLVRGIKREDVERGQVVVKPG
Mvan_1282|M.vanbaalenii_PYR-1       RPDTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPG
TH_4394|M.thermoresistible__bu      RPETTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVQPG
MAB_3848c|M.abscessus_ATCC_199      KDTTTKTTVTGVEMFRKLLDQGQAGDNVGLLVRGVKREDVERGQVVVKPG
                                    :   ***************************:**:*********** :**

Mb0704|M.bovis_AF2122/97            TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
Rv0685|M.tuberculosis_H37Rv         TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MAV_4489|M.avium_104                TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MMAR_1014|M.marinum_M               TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MUL_0766|M.ulcerans_Agy99           TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MLBr_01877|M.leprae_Br4923          TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MSMEG_1401|M.smegmatis_MC2_155      TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
Mflv_5075|M.gilvum_PYR-GCK          TTTPHTEFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
Mvan_1282|M.vanbaalenii_PYR-1       TTTPHTDFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
TH_4394|M.thermoresistible__bu      TTTPHTEFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MAB_3848c|M.abscessus_ATCC_199      TTTPHTEFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
                                    ******:***.***************************************

Mb0704|M.bovis_AF2122/97            TEMVMPGDNTNISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
Rv0685|M.tuberculosis_H37Rv         TEMVMPGDNTNISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
MAV_4489|M.avium_104                TEMVMPGDNTNISVKLIQPVAMDEGLRFAIREGGRTVGAGRVVKIIK
MMAR_1014|M.marinum_M               TEMVMPGDNTNISVKLIQPVAMDDGLRFAIREGGRTVGAGRVVKIIK
MUL_0766|M.ulcerans_Agy99           TEMVMPGDNTNISVKLIQPVAMDDGLRFAIREGGRTVGAGRVVKIIK
MLBr_01877|M.leprae_Br4923          TEMVMPGDNTNISVTLIQPVAMDEGLRFAIREGGRTVGAGRVVKIIK
MSMEG_1401|M.smegmatis_MC2_155      TEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
Mflv_5075|M.gilvum_PYR-GCK          TEMVMPGDNTDIAVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
Mvan_1282|M.vanbaalenii_PYR-1       TEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
TH_4394|M.thermoresistible__bu      TEMVMPGDNTDISVKLIQPVAMEEGLRFAIREGGRTVGAGRVTKIIK
MAB_3848c|M.abscessus_ATCC_199      TEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
                                    **********:*:*.*******::******************.****