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AKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDQYPDLNESRAFDQIDNAPEERQRGITINISHVE YQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKAD MVDDEELIELVEMEVRELLAAQDFDEDAPVVKVSALKALEGDEKWVKSVQELMAAVDESIPDPVRETDKP FLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGIRPTVTKTTVTGVEMFRKLLDQGQAGDNVGLLV RGIKREDVERGQVVVKPGTTTPHTEFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTE MVMPGDNTDIAVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5075 | - | - | 100% (396) | elongation factor Tu |
| M. gilvum PYR-GCK | Mflv_2272 | - | 2e-20 | 26.40% (322) | bifunctional sulfate adenylyltransferase subunit |
| M. gilvum PYR-GCK | Mflv_2163 | - | 5e-19 | 29.22% (308) | GTP-binding protein TypA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0704 | tuf | 0.0 | 94.19% (396) | elongation factor Tu |
| M. tuberculosis H37Rv | Rv0685 | tuf | 0.0 | 94.19% (396) | elongation factor Tu |
| M. leprae Br4923 | MLBr_01877 | tuf | 0.0 | 93.94% (396) | elongation factor Tu |
| M. abscessus ATCC 19977 | MAB_3848c | - | 0.0 | 93.45% (397) | elongation factor Tu |
| M. marinum M | MMAR_1014 | tuf | 0.0 | 94.44% (396) | iron-regulated elongation factor EF-Tu, Tuf |
| M. avium 104 | MAV_4489 | tuf | 0.0 | 95.45% (396) | elongation factor Tu |
| M. smegmatis MC2 155 | MSMEG_1401 | tuf | 0.0 | 95.96% (396) | elongation factor Tu |
| M. thermoresistible (build 8) | TH_4394 | - | 0.0 | 93.43% (396) | PUTATIVE translation elongation factor 1A (EF-1A/EF-Tu) |
| M. ulcerans Agy99 | MUL_0766 | tuf | 0.0 | 94.44% (396) | elongation factor Tu |
| M. vanbaalenii PYR-1 | Mvan_1282 | - | 0.0 | 97.22% (396) | elongation factor Tu |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5075|M.gilvum_PYR-GCK MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDQYPDLNESRAFD
Mvan_1282|M.vanbaalenii_PYR-1 MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPDLNESRAFD
Mb0704|M.bovis_AF2122/97 MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPDLNETKAFD
Rv0685|M.tuberculosis_H37Rv MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPDLNETKAFD
MAV_4489|M.avium_104 MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPDLNESRAFD
MMAR_1014|M.marinum_M MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNESRAFD
MUL_0766|M.ulcerans_Agy99 MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNESRAFD
MLBr_01877|M.leprae_Br4923 MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPNLNESRAFD
MSMEG_1401|M.smegmatis_MC2_155 MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKFPDLNESRAFD
TH_4394|M.thermoresistible__bu VAKAKFERTKPHVNIGTIGHVDHGKTTTTAAITKVLHDKYPELNESRAFE
MAB_3848c|M.abscessus_ATCC_199 MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPDLNEASAFD
:*****:******************** **********::*:***: **:
Mflv_5075|M.gilvum_PYR-GCK QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
Mvan_1282|M.vanbaalenii_PYR-1 QIDNAPEERQRGITINISHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
Mb0704|M.bovis_AF2122/97 QIDNAPEERQRGITINIAHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
Rv0685|M.tuberculosis_H37Rv QIDNAPEERQRGITINIAHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
MAV_4489|M.avium_104 QIDNAPEERQRGITINISHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
MMAR_1014|M.marinum_M QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
MUL_0766|M.ulcerans_Agy99 QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
MLBr_01877|M.leprae_Br4923 QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
MSMEG_1401|M.smegmatis_MC2_155 QIDNAPEERQRGITINISHVEYQTDKRHYAHVDAPGHADYIKNMITGAAQ
TH_4394|M.thermoresistible__bu QIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
MAB_3848c|M.abscessus_ATCC_199 QIDNAPEEKARGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQ
********: *******:******:*************************
Mflv_5075|M.gilvum_PYR-GCK MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEELIE
Mvan_1282|M.vanbaalenii_PYR-1 MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEELIE
Mb0704|M.bovis_AF2122/97 MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADAVDDEELLE
Rv0685|M.tuberculosis_H37Rv MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADAVDDEELLE
MAV_4489|M.avium_104 MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEELLE
MMAR_1014|M.marinum_M MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLE
MUL_0766|M.ulcerans_Agy99 MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLE
MLBr_01877|M.leprae_Br4923 MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLE
MSMEG_1401|M.smegmatis_MC2_155 MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELIE
TH_4394|M.thermoresistible__bu MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDPELLE
MAB_3848c|M.abscessus_ATCC_199 MDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDMVDDEELLE
***************************************:* *** **:*
Mflv_5075|M.gilvum_PYR-GCK LVEMEVRELLAAQDFD-EDAPVVKVSALKALEGDEKWVKSVQELMAAVDE
Mvan_1282|M.vanbaalenii_PYR-1 LVEMEVRELLAAQDFD-EEAPVVKVSALKALEGDEKWVKSVEELMEAVDE
Mb0704|M.bovis_AF2122/97 LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDAKWVASVEELMNAVDE
Rv0685|M.tuberculosis_H37Rv LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDAKWVASVEELMNAVDE
MAV_4489|M.avium_104 LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDAKWVESVEQLMEAVDE
MMAR_1014|M.marinum_M LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDPKWVESVEQLMDAVDE
MUL_0766|M.ulcerans_Agy99 LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDPKWVESVEQLMDAVDE
MLBr_01877|M.leprae_Br4923 LVEMEVRELLAAQEFD-EDAPVVRVSALKALEGDAKWVESVTQLMDAVDE
MSMEG_1401|M.smegmatis_MC2_155 LVEMEVRELLAAQDFD-EEAPVVRVSALKALEGDPKWVKSVEELMEAVDA
TH_4394|M.thermoresistible__bu LVEMEVRELLASQEFD-ENAPVIPISALKALEGDPKWVKSVEDLMEAVDE
MAB_3848c|M.abscessus_ATCC_199 LVEMEVRELLSSQDFDGDNAPVVRVSALKALEGDAEWGKTVADLMDAVDE
**********::*:** ::***: :********* :* :* :** ***
Mflv_5075|M.gilvum_PYR-GCK SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
Mvan_1282|M.vanbaalenii_PYR-1 SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGIINVNEEVEIVGI
Mb0704|M.bovis_AF2122/97 SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
Rv0685|M.tuberculosis_H37Rv SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
MAV_4489|M.avium_104 SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
MMAR_1014|M.marinum_M SIPDPVRETDRPFLMPVEDVFTITGRGTVVTGRVERGIINVNEEVEIVGI
MUL_0766|M.ulcerans_Agy99 SIPDPVRETDRPFLMPVEDVFTITGRGTVVTGRVERGIINVNEEVEIVGI
MLBr_01877|M.leprae_Br4923 SIPAPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVVNVNEEVEIVGI
MSMEG_1401|M.smegmatis_MC2_155 SIPDPVRETDKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEEVEIVGI
TH_4394|M.thermoresistible__bu SIPDPVRDTDKPFLMPIEDVFTITGRGTVVTGRIERGVINVNDEVEIVGI
MAB_3848c|M.abscessus_ATCC_199 SIPDPVRETEKPFLMPVEDVFTITGRGTVVTGRVERGVINVNEDVEIVGI
*** ***:*::*****:****************:***::***::******
Mflv_5075|M.gilvum_PYR-GCK RPTVTKTTVTGVEMFRKLLDQGQAGDNVGLLVRGIKREDVERGQVVVKPG
Mvan_1282|M.vanbaalenii_PYR-1 RPDTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPG
Mb0704|M.bovis_AF2122/97 RPSTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGVKREDVERGQVVTKPG
Rv0685|M.tuberculosis_H37Rv RPSTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGVKREDVERGQVVTKPG
MAV_4489|M.avium_104 RPSSTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVTKPG
MMAR_1014|M.marinum_M RPTSTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPG
MUL_0766|M.ulcerans_Agy99 RPTSTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPG
MLBr_01877|M.leprae_Br4923 RQTTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVIKPG
MSMEG_1401|M.smegmatis_MC2_155 RPETTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPG
TH_4394|M.thermoresistible__bu RPETTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVQPG
MAB_3848c|M.abscessus_ATCC_199 KDTTTKTTVTGVEMFRKLLDQGQAGDNVGLLVRGVKREDVERGQVVVKPG
: ***************************:**:*********** :**
Mflv_5075|M.gilvum_PYR-GCK TTTPHTEFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
Mvan_1282|M.vanbaalenii_PYR-1 TTTPHTDFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
Mb0704|M.bovis_AF2122/97 TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
Rv0685|M.tuberculosis_H37Rv TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MAV_4489|M.avium_104 TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MMAR_1014|M.marinum_M TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MUL_0766|M.ulcerans_Agy99 TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MLBr_01877|M.leprae_Br4923 TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MSMEG_1401|M.smegmatis_MC2_155 TTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
TH_4394|M.thermoresistible__bu TTTPHTEFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
MAB_3848c|M.abscessus_ATCC_199 TTTPHTEFEGSVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEG
******:***.***************************************
Mflv_5075|M.gilvum_PYR-GCK TEMVMPGDNTDIAVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
Mvan_1282|M.vanbaalenii_PYR-1 TEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
Mb0704|M.bovis_AF2122/97 TEMVMPGDNTNISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
Rv0685|M.tuberculosis_H37Rv TEMVMPGDNTNISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
MAV_4489|M.avium_104 TEMVMPGDNTNISVKLIQPVAMDEGLRFAIREGGRTVGAGRVVKIIK
MMAR_1014|M.marinum_M TEMVMPGDNTNISVKLIQPVAMDDGLRFAIREGGRTVGAGRVVKIIK
MUL_0766|M.ulcerans_Agy99 TEMVMPGDNTNISVKLIQPVAMDDGLRFAIREGGRTVGAGRVVKIIK
MLBr_01877|M.leprae_Br4923 TEMVMPGDNTNISVTLIQPVAMDEGLRFAIREGGRTVGAGRVVKIIK
MSMEG_1401|M.smegmatis_MC2_155 TEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
TH_4394|M.thermoresistible__bu TEMVMPGDNTDISVKLIQPVAMEEGLRFAIREGGRTVGAGRVTKIIK
MAB_3848c|M.abscessus_ATCC_199 TEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIIK
**********:*:*.*******::******************.****