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M. thermoresistible (build 8) TH_4348 (-)

annotation: protein of unknown function DUF955
coordinates: 1951214 - 1952641
length: 476

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4348--100% (476)protein of unknown function DUF955

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0474c-0.081.55% (477) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_0109-0.080.91% (482) hypothetical protein Mflv_0109
M. tuberculosis H37RvRv0465c-0.081.76% (477) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4118-0.082.88% (473) transcriptional regulatory protein
M. marinum MMMAR_0790-0.081.80% (478) transcriptional regulatory protein
M. avium 104MAV_4684-0.082.22% (478) DNA-binding protein
M. smegmatis MC2 155MSMEG_0906-0.084.60% (474) DNA-binding protein
M. ulcerans Agy99MUL_4534-0.081.80% (478) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_0799-0.080.25% (476) hypothetical protein Mvan_0799

CLUSTAL 2.0.9 multiple sequence alignment


Mb0474c|M.bovis_AF2122/97           MSKTYVGSRVRQLRNERGFSQAALAQMLEISPSYLDQIEHDVRPLTVAVL
Rv0465c|M.tuberculosis_H37Rv        MSKTYVGSRVRQLRNERGFSQAALAQMLEISPSYLNQIEHDVRPLTVAVL
MMAR_0790|M.marinum_M               MSKTFVGSRVRQLRNERGFSQAALAQLLEISPSYLNQIEHDVRPLTVAVL
MUL_4534|M.ulcerans_Agy99           MSKTFVGSRVRQLRNERGFSQAALAQLLEISPSYLNQIEHDVRPLTVAVL
MAV_4684|M.avium_104                MSKTFVGSRVRQLRHERGFSQAALAQMLEISPSYLNQIEHDVRPLTVAVL
MAB_4118|M.abscessus_ATCC_1997      MSKTYVGGRLRQLRSERGFSQAALAQMLEISPSYLNQIEHDVRPLTVAVL
TH_4348|M.thermoresistible__bu      VAKTYVGSRVRQLRNERGYSQAALAEMLGISPSYLNQIEHDVRPLTVPVL
MSMEG_0906|M.smegmatis_MC2_155      MPKTFVGSRVRQLRSERGFSQAALAQMLDISPSYLNQIEHDVRPLTVAVL
Mflv_0109|M.gilvum_PYR-GCK          MAKTFVGARVRQLRSERGFSQAALAQMLEISPSYLNQIEHDVRPLTVAVL
Mvan_0799|M.vanbaalenii_PYR-1       MAKTFVGARIRQLRSERGFSQAALAQMLEISPSYLNQIEHDVRPLTVAVL
                                    :.**:**.*:**** ***:******::* ******:***********.**

Mb0474c|M.bovis_AF2122/97           LRITEVFGVDATFFASQDDTRLVAELREVTLDRDLDIA-IDPHEVAEMVS
Rv0465c|M.tuberculosis_H37Rv        LRITEVFGVDATFFASQDDTRLVAELREVTLDRDLDIA-IDPHEVAEMVS
MMAR_0790|M.marinum_M               LRITEVFGVDATFFSSQDDTRLVAELREVTMDRDLDIS-VDPTEVAEMVS
MUL_4534|M.ulcerans_Agy99           LRITEVFGVDATFFSSQDDTRLVAELREVTMDRDLDIS-VDPTEVAEMVS
MAV_4684|M.avium_104                LRITEVFGVDATFFSSQDDTRLVAELREVTMDRDLDID-VDPTEVAEMVS
MAB_4118|M.abscessus_ATCC_1997      LRITEVFGVDATFFSSQDDSRLIAELREVVQDKDLDID-VDPAEIADVVA
TH_4348|M.thermoresistible__bu      LRITDLFGVDATFFAPEDNTRLIAELREVTLDRDLDIN-VDMTEIADMVS
MSMEG_0906|M.smegmatis_MC2_155      LRITEVFGVDATFFSPQDDTRLVAELREVTLDRDLGASDVDLTEVADMVA
Mflv_0109|M.gilvum_PYR-GCK          LRITEVFGVDATFFASQDDTRLIAELREVTMDRDLDVE-VDPAEIAEVVA
Mvan_0799|M.vanbaalenii_PYR-1       LRITEVFGVDATFFASQDDTRLIAELREVLMDRDLDVD-VDPAEVADMVG
                                    ****::********:.:*::**:******  *:**.   :*  *:*::*.

Mb0474c|M.bovis_AF2122/97           AHPGLARAVVNLHRRYRITTAQLAAATEERFSD--------GSGRGSITM
Rv0465c|M.tuberculosis_H37Rv        AHPGLACAVVNLHRRYRITTAQLAAATEERFSD--------GSGRGSITM
MMAR_0790|M.marinum_M               AHPSLARAMVNLHRRYRITTAQLAAATEERYSD--------GSGTGSITM
MUL_4534|M.ulcerans_Agy99           AHPSLARAMVNLHRRYRITTAQLAAATEERYSD--------GSGTGSITM
MAV_4684|M.avium_104                AHPGLARAVVNLHRRYRITTAQLAAATEERFFD--------GSGTGSITM
MAB_4118|M.abscessus_ATCC_1997      GHPALARAMVNLHRRYRITTTQLAAATEDRYTD--------GSGSGSITM
TH_4348|M.thermoresistible__bu      AHPELARAMVNLHQRYRRTTTQLAAATEDRYHDS----SGFGSGSGSITM
MSMEG_0906|M.smegmatis_MC2_155      SHPKLARAMVNLHRRYRLATTQLAAATEDRYSD--------GSGSGAITM
Mflv_0109|M.gilvum_PYR-GCK          SHPSLARAMVNLHRRYQLTTTQLAAATEDRFNTAGLSSAGGGSGSGAISM
Mvan_0799|M.vanbaalenii_PYR-1       SHPALARAMVNLHRRYQLTTTQLAAATEDRFN------VGSGGGSGAITM
                                    .** ** *:****:**: :*:*******:*:          *.* *:*:*

Mb0474c|M.bovis_AF2122/97           PHEEVRDYFYQRQNYLHALDTAAEDLTAQMRMHHGDLARELTRRLTEVHG
Rv0465c|M.tuberculosis_H37Rv        PHEEVRDYFYQRQNYLHALDTAAEDLTAQMRMHHGDLARELTRRLTEVHG
MMAR_0790|M.marinum_M               PHEEVRDYFYQRQNYLHELDAAAEDLTIQMRLHHGDLRSELTRRLTEVHG
MUL_4534|M.ulcerans_Agy99           PHEEVRDYFYQRQNYLHELDAAAEDLTIQMRLHHGDLRSELTRRLTEVHG
MAV_4684|M.avium_104                PHEEVRDYFYQRQNYLHELDTAAEDLTIKMRLHHGDLARELTRRLTEVHG
MAB_4118|M.abscessus_ATCC_1997      PHEEVRDYFYQRHNYLHELDTAAEDLTVRMRMHRADLAREIADRLTEVHG
TH_4348|M.thermoresistible__bu      PHEEVRDYFYQRQNYLHELDTAAEDLTIRMGMTRTELARQLADRLTMVHG
MSMEG_0906|M.smegmatis_MC2_155      PHEEVRDYFYERQNYLHELDTAAEDLTARMRMHSGDLAAELTNRLTSVHG
Mflv_0109|M.gilvum_PYR-GCK          PHEEVRDYFYQRQNYLHELDLAAENLTADMRVHRGELAGDLADRLRFVHG
Mvan_0799|M.vanbaalenii_PYR-1       PHEEVRDYFYQRQNYLHDLDTAAEALTADMRVHRGDLAGDLSDRLRFVHG
                                    **********:*:**** ** *** **  * :   :*  ::: **  ***

Mb0474c|M.bovis_AF2122/97           VRINKRIDLGDTVLHRYDPATNTLEISSHLSPGQQVFKMAAELAYLEFGD
Rv0465c|M.tuberculosis_H37Rv        VRINKRIDLGDTVLHRYDPATNTLEISSHLSPGQQVFKMAAELAYLEFGD
MMAR_0790|M.marinum_M               VRITRRIDLGDTVLHRFDPATKTLEISNHLASGQQVFKMAAELAYLEFGD
MUL_4534|M.ulcerans_Agy99           VRITRRIDLGDTVLHRLDPATMTLEISNHLASGQQVFKMAAELAYLEFGD
MAV_4684|M.avium_104                VHINRRIDLGDTVLHRYDPETKTLEISNHLSWGQQVFKMAAELAYLEFGD
MAB_4118|M.abscessus_ATCC_1997      VQIARRIDLGDSVLHKYDPASKTLEISNHLSGGQQVFKLAAELAYLEYGD
TH_4348|M.thermoresistible__bu      VHIVRRVDMPETVLHRYDPETRTLELNNQLSSGQQVFKMAAELGYLEFGD
MSMEG_0906|M.smegmatis_MC2_155      VRVVRRIDMGETVLHRYDPATKTLEMSNHISRGQQVFKMAAELAYLEFGD
Mflv_0109|M.gilvum_PYR-GCK          VTIIRRIDLGEVVMHRYDPDTRRLEMSAQLSAGQRVFRMAAELAYLECGD
Mvan_0799|M.vanbaalenii_PYR-1       VTVIRSVDLGEGVLHRYDPATRRLEVGAHLSSGQTVFRMAAELAYLECGE
                                    * : : :*: : *:*: ** :  **:. ::: ** **::****.*** *:

Mb0474c|M.bovis_AF2122/97           LIDAMVTDGKFTSAESRTLARLGLANYFAAATVLPYRQFHDVAENFRYDV
Rv0465c|M.tuberculosis_H37Rv        LIDAMVTDGKFTSAESRTLARLGLANYFAAATVLPYRQFHDVAENFRYDV
MMAR_0790|M.marinum_M               LIDAMVTDGKFTSDESRTLARLGLANYFAAAAVLPYRQFHDVAENFRYDV
MUL_4534|M.ulcerans_Agy99           LIDAMVTDGKFTSDESRTLARLGLANYFAAAAVLPYRQFHDVAENFRYDV
MAV_4684|M.avium_104                LIDSLVAQGKFTSEESHKLARLGLANYFAAAAVLPYRQFHDVAENFRYDV
MAB_4118|M.abscessus_ATCC_1997      LIDTMVDDGKFTSEESRKLARLGLANYFAAATVLPYRQFHGVAEDFQYDI
TH_4348|M.thermoresistible__bu      LIDKLVDEGHFTSDESRKLARLGLANYFAAATVLPYRQFHGVTENFRYDI
MSMEG_0906|M.smegmatis_MC2_155      LIDKLVDEGRFTSDESRTLARLGLANYFAAATVLPYRQFHDVAENFRYDI
Mflv_0109|M.gilvum_PYR-GCK          LIEKLVAEGHFTSEESRKLARMGLANYFAAATVLPYGQFHEVAEKFRYDV
Mvan_0799|M.vanbaalenii_PYR-1       LIDKLVDEGKFTSEESRKLARMGLANYFAAAAVLPYGQFHEVAEKFRYDI
                                    **: :* :*:*** **:.***:*********:**** *** *:*.*:**:

Mb0474c|M.bovis_AF2122/97           ERLSAFYSVSYETIAHRLSTLQRPSMRGVPFTFVQVDRAGNMSKRQSATG
Rv0465c|M.tuberculosis_H37Rv        ERLSAFYSVSYETIAHRLSTLQRPSMRGVPFTFVRVDRAGNMSKRQSATG
MMAR_0790|M.marinum_M               ERLSAFYSVSYETIAHRLSTLQRPSMRGVPFSFIRVDRAGNMSKRQSATG
MUL_4534|M.ulcerans_Agy99           ERLSAFYSVSYETIAHRLSTLQRPSMRGVPFSFIRVDRAGNMSKRQSATG
MAV_4684|M.avium_104                ERLSSFYSVSYETIAHRLSTLQRPSMRGVPFSFIRVDRAGNMSKRQSATG
MAB_4118|M.abscessus_ATCC_1997      ERLSAFYSVSYETVCHRLSTLQRPSMRGVPFSFVRVDRAGNMSKRQSATG
TH_4348|M.thermoresistible__bu      ERLSAFYRVSYETICHRLSTLQRPSMRGVPFSFVRVDRAGNMSKRQSASG
MSMEG_0906|M.smegmatis_MC2_155      ERLSAFYQVSYETIGHRLSTLQRPSMRGVPFSFVRVDRAGNMSKRQSATG
Mflv_0109|M.gilvum_PYR-GCK          ERLSAYYSVSYETICHRLSTLQRPSMRGVPFSFVRVDRAGNMSKRQSATG
Mvan_0799|M.vanbaalenii_PYR-1       ERLSAYYSVSYETTCHRLSTLQRPSMRGVPFSFVRVDRAGNMSKRQSATG
                                    ****::* *****  ****************:*::*************:*

Mb0474c|M.bovis_AF2122/97           FHFSSSGGTCPLWNVYETFANPGKILVQIAQMPDGRNYLWVARTVELRAA
Rv0465c|M.tuberculosis_H37Rv        FHFSSSGGTCPLWNVYETFANPGKILVQIAQMPDGRNYLWVARTVELRAA
MMAR_0790|M.marinum_M               FHFSSSGGTCPLWNVYETFANPGKILVQIAQMPDGRNYMWVARTVERRAA
MUL_4534|M.ulcerans_Agy99           FHFSSSGGTCPLWNVYETFANPGKILVQIAQMPDGRNYMWVARTVERRAA
MAV_4684|M.avium_104                FHFSSSGGTCPLWNVYETFANPGKILVQIAQMPDGRNYMWVARTVERRAA
MAB_4118|M.abscessus_ATCC_1997      FHFSSSGGTCPLWNVYETFGNPGKILVQVAQMPDGRNYLWVARTVERRAS
TH_4348|M.thermoresistible__bu      FHFSSSGGTCPLWNVYETFAYPGKIMVQIAEMPDGRKYLWVARTVERRAS
MSMEG_0906|M.smegmatis_MC2_155      FHFSSSGGTCPLWNVYETFAYPGKILVQIAQMPDGRHYMWVARTVERRAH
Mflv_0109|M.gilvum_PYR-GCK          FHFSSSGGTCPLWNVYETFANPGKIGVQIAEMPDGRAYMWVARTVERRAA
Mvan_0799|M.vanbaalenii_PYR-1       FHFSSSGGTCPLWNVYETFANPGKISVQIAEMPDGRAYMWVARTVERRAS
                                    *******************. **** **:*:***** *:******* ** 

Mb0474c|M.bovis_AF2122/97           RYGQPGKTFAIGLGCELRHAHRLVYSEGLDLSGDPNTAATPIGAGCRVCE
Rv0465c|M.tuberculosis_H37Rv        RYGQPGKTFAIGLGCELRHAHRLVYSEGLDLSGDPNTAATPIGAGCRVCE
MMAR_0790|M.marinum_M               RYGQPGKTFAIGLGCELRHAHRLVYSEGLDLSGDPNIAATPIGAGCRVCE
MUL_4534|M.ulcerans_Agy99           RYGQPGKTFAIGLGCELRHAHRLVYSEGLDLSGDPNIAATPIGAGCRVCE
MAV_4684|M.avium_104                RYGQPGKTFAIGLGCELRHAHRLVYSEGLDVSGGPGTVATPIGAGCRVCE
MAB_4118|M.abscessus_ATCC_1997      RYGQPGKTFAIGLGCELRHAHRLVYSQGLDLSSEG--ATTPIGVGCRVCE
TH_4348|M.thermoresistible__bu      RYGQPGKTFAIGLGCELRHAHRLVYSEGLDLSGEN---ASPIGVGCRVCE
MSMEG_0906|M.smegmatis_MC2_155      RYGQPGKTFAIGLGCELRHAHRLVYSEGLDLSGNV---STPIGAGCRVCE
Mflv_0109|M.gilvum_PYR-GCK          RYGQPGKTFAIGLGCELRHAQRLVYSEGLDLSGDPSVRATPIGAGCRVCE
Mvan_0799|M.vanbaalenii_PYR-1       RYGQPGKTFAIGLGCELRHAQRLVYSEGL-VTGDPNVPATPIGAGCRVCE
                                    ********************:*****:** ::.     ::***.******

Mb0474c|M.bovis_AF2122/97           RDNCPQRAFPALGRALDLDEHRSTVSPYLVKQL------
Rv0465c|M.tuberculosis_H37Rv        RDNCPQRAFPALGRALDLDEHRSTVSPYLVKQL------
MMAR_0790|M.marinum_M               RDNCPQRAFPALGRALDLDEHRSTVSPYLVKQP------
MUL_4534|M.ulcerans_Agy99           RDNCPQRAFPALGRALDLDEHRSTVSPYLVKQP------
MAV_4684|M.avium_104                RDNCPQRAFPALGRALDLDEHRSTVSPYLVKQP------
MAB_4118|M.abscessus_ATCC_1997      RDNCPQRAFPALGRALDLDEHRSTVSPYLVLQEGAHP--
TH_4348|M.thermoresistible__bu      RDNCPQRAFPALGRALDLDEHRSTVSPYLVR----RP--
MSMEG_0906|M.smegmatis_MC2_155      RDNCPQRAFPALGKALDLDEHRSTVSPYLVRPSEVKPLG
Mflv_0109|M.gilvum_PYR-GCK          RDNCPQRAFPALGRALDIDEHRSTVSPYLVRQP------
Mvan_0799|M.vanbaalenii_PYR-1       RDNCPQRAFPALGRALDIDEHRSTVSPYLVRQQ------
                                    *************:***:************