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M. thermoresistible (build 8) TH_3936 (-)

annotation: putative AMP-dependent synthetase and ligase
coordinates: 1281871 - 1282188
length: 106

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3936--100% (106)putative AMP-dependent synthetase and ligase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0966c-5e-2448.57% (105) hypothetical protein Mb0966c
M. gilvum PYR-GCKMflv_3450-8e-1944.55% (101) anti-sigma-factor antagonist
M. tuberculosis H37RvRv0941c-5e-2448.57% (105) hypothetical protein Rv0941c
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4567-2e-2143.81% (105) hypothetical protein MMAR_4567
M. avium 104MAV_1062-3e-2246.67% (105) stas domain-containing protein
M. smegmatis MC2 155MSMEG_5551-2e-2148.08% (104) stas domain-containing protein
M. ulcerans Agy99MUL_4427-1e-2143.81% (105) hypothetical protein MUL_4427
M. vanbaalenii PYR-1Mvan_3207-2e-1947.17% (106) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3450|M.gilvum_PYR-GCK          ------------------------------------MQVSATPGPGGGTA
Mvan_3207|M.vanbaalenii_PYR-1       MRRWPPKPRKHSPCCGSGSPSPSPRRARPTMVDRTHVHVSASRSLDGCAM
MSMEG_5551|M.smegmatis_MC2_155      -----------------------------MTRSRSPITISVT-SRGEITL
Mb0966c|M.bovis_AF2122/97           ------------------------MVAVSTAAKSPTALAIAVRTQDSVVI
Rv0941c|M.tuberculosis_H37Rv        ------------------------MVAVSTAAKSPTALAIAVRTQDSVVI
MMAR_4567|M.marinum_M               ---------------------------MNATAKSPNALAIDTRSEDSLVV
MUL_4427|M.ulcerans_Agy99           ---------------------------MNATAKSPNALAIDTRSEDSLVV
MAV_1062|M.avium_104                -------------------------------------------------M
TH_3936|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3450|M.gilvum_PYR-GCK          LTITGTLDGSTYHEVRDSIIKAALEEPDAVIVDVSGLEVPSESAWKAITS
Mvan_3207|M.vanbaalenii_PYR-1       LVLSGTLDSWTYREVRNSVIKAALDEPKAVVVDVSDLHVPASSAWTAFTS
MSMEG_5551|M.smegmatis_MC2_155      LTVDGVLDSTTYREVRDTVIKAALSEPRAVVVNVSRLVVPTETAWSVFTS
Mb0966c|M.bovis_AF2122/97           LTADGALDSSSSALLRDSLTRATLEQPSAVIVNVTELQVAEESAWSVFIS
Rv0941c|M.tuberculosis_H37Rv        LTADGALDSSSSALLRDSLTRATLEQPSAVIVNVTELQVAEESAWSVFIS
MMAR_4567|M.marinum_M               LSVEGAIDSTNCAALRDAIIKATLDEPSAVVVNVSALQVPDEASWSIFVS
MUL_4427|M.ulcerans_Agy99           LSVEGAIDSTNCAALRDAIIKATLDEPSAVVVNVSALQVPDEASWSIFVS
MAV_1062|M.avium_104                LTVDGVLDPASSTLLRDRIIKATLDQTPAVVIDVSALKVNAESTWSTFMA
TH_3936|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3450|M.gilvum_PYR-GCK          AHWHVRRWPHVPILLVCDEPARRAAITRSGVTRHVRLHP--DHTSAARCV
Mvan_3207|M.vanbaalenii_PYR-1       ARWHVSTWPDVPIVLVCAQEERRAAIQRSGASRWVPVHP--DEASAAASI
MSMEG_5551|M.smegmatis_MC2_155      ARWHVCVWPDVPVLLVCDHQQGRASLWRNGIQRYVPVCSTLDEACATVLA
Mb0966c|M.bovis_AF2122/97           ARWQADFRADVPVLLVCGHRAGRAAVTRTGVARFMPVYPT-EKAASKAIG
Rv0941c|M.tuberculosis_H37Rv        ARWQADFRADVPVLLVCGHRAGRAAVTRTGVARFMPVYPT-EKAASKAIG
MMAR_4567|M.marinum_M               ARWQVDTPQHVPILLVCASRAGRELITRTGVTRFMPVYPT-EKGAIKAVG
MUL_4427|M.ulcerans_Agy99           ARWQVDTPQHVPILLVCASRAGRELITRTGVTRFMPVYPT-EKRAIKAVG
MAV_1062|M.avium_104                TYWQLGNTPHVPLVLVCAKKAAREAIARSGITHFMPVYSS-QKAALKALG
TH_3936|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3450|M.gilvum_PYR-GCK          AAPTWMRRRADVELDAGADCLQVMREVLARRLSEWGRPDMTLAASTVATV
Mvan_3207|M.vanbaalenii_PYR-1       GEPHRLRRRARDELAADRSSLTRARGLVARWLTEWACPDLILAASTVATV
MSMEG_5551|M.smegmatis_MC2_155      DRMSPLRRRARAHLPAVHSSVRRSRELVTDWLLNWSLTKYIPVTCVVTDA
Mb0966c|M.bovis_AF2122/97           RLARRNFKRSDAQLPANLNSLRESRQLVREWLTQWSRPGLIPVALVVVNV
Rv0941c|M.tuberculosis_H37Rv        RLARRNFKRSDAQLPANLNSLRESRQLVREWLTQWSRPGLIPVALVVVNV
MMAR_4567|M.marinum_M               RLARRKVRYAQVQLPANLGSLRESRKLVREWLTSWSKPGLIPVALVIVNV
MUL_4427|M.ulcerans_Agy99           RLARRKVRYAQVQLPANLGSLRESRKLVREWLTSWSKPGLIPVALVIVNV
MAV_1062|M.avium_104                PNSRRIVRRADAQLPADLTSLRESRRLVREWLTTWSQSKLIPVALVVVNV
TH_3936|M.thermoresistible__bu      ---------------------------VADVLARWSQEELIGVAKVVITT
                                                               :   *  *.      .: .:  .

Mflv_3450|M.gilvum_PYR-GCK          LVENVLEHTESRPTLIVETAGDFVAVAVSDENRIPPARREDPGTGAHTVS
Mvan_3207|M.vanbaalenii_PYR-1       LIENVLEHTSSRPILVLEAFDGCVTVAVSDQCPTPAALHESSGSGAHTVS
MSMEG_5551|M.smegmatis_MC2_155      LVENVLEHTLSAPKIMLENRGDTVSIAVEDESPAPAVRHEDPYRGGGRLS
Mb0966c|M.bovis_AF2122/97           FVENVLKHTGSDPVMRIESDGPTATIAVSDGSSAPAVRLASPPKG-IDVS
Rv0941c|M.tuberculosis_H37Rv        FVENVLKHTGSDPVMRIESDGPTATIAVSDGSSAPAVRLASPPKG-IDVS
MMAR_4567|M.marinum_M               FVENVLEHTGSDPVIKVQCDGTAATIAVSDGSNAPAIRLQTPPKG-IDVS
MUL_4427|M.ulcerans_Agy99           FVENVLEHTGSDPVIKVQCDGTAATIAVSDGSNAPAIRLQTPPKG-IDVS
MAV_1062|M.avium_104                FVENVLEHTASVPVMRVEAQGTTATIAVSDASNTPAVRLPSPVKG-IDVS
TH_3936|M.thermoresistible__bu      FVENVLVHTDSAPGVRLETDGQTVTVAVEDDDPAPPTLREDREAA-AAPA
                                    ::**** ** * * : ::  .  .::**.*    *.        .    :

Mflv_3450|M.gilvum_PYR-GCK          DLAIVTALSHAWGCTPTTTGKTVWALLAPENQF
Mvan_3207|M.vanbaalenii_PYR-1       GLAIVATLSRSWGSIPTANGKTVWTVLGPESRL
MSMEG_5551|M.smegmatis_MC2_155      GLALVASIARSWGCTPTTTGKTVWALIGPESCF
Mb0966c|M.bovis_AF2122/97           GLAIVAALSRAWGSSPTSSGKTVWAIIGPENQL
Rv0941c|M.tuberculosis_H37Rv        GLAIVAALSRAWGSSPTSSGKTVWAIIGPENQL
MMAR_4567|M.marinum_M               GLAIVEALCRAWGSTPTATGKTVWAIIGPENQL
MUL_4427|M.ulcerans_Agy99           GLAIVEALCRAWGSTPTATGKTVWAIIGPENQL
MAV_1062|M.avium_104                GLAIVDALSRAWGSTPTASGKTVWAIIGPENQL
TH_3936|M.thermoresistible__bu      GLHTVARLVRAWGTAPSPAGKTVWAVLGPENRI
                                    .*  *  : ::**  *:. *****:::.**. :