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MRRWPPKPRKHSPCCGSGSPSPSPRRARPTMVDRTHVHVSASRSLDGCAMLVLSGTLDSWTYREVRNSVI KAALDEPKAVVVDVSDLHVPASSAWTAFTSARWHVSTWPDVPIVLVCAQEERRAAIQRSGASRWVPVHPD EASAAASIGEPHRLRRRARDELAADRSSLTRARGLVARWLTEWACPDLILAASTVATVLIENVLEHTSSR PILVLEAFDGCVTVAVSDQCPTPAALHESSGSGAHTVSGLAIVATLSRSWGSIPTANGKTVWTVLGPESR L
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3207 | - | - | 100% (281) | anti-sigma-factor antagonist |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0966c | - | 7e-54 | 44.63% (242) | hypothetical protein Mb0966c |
| M. gilvum PYR-GCK | Mflv_3450 | - | 6e-72 | 56.97% (244) | anti-sigma-factor antagonist |
| M. tuberculosis H37Rv | Rv0941c | - | 7e-54 | 44.63% (242) | hypothetical protein Rv0941c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4567 | - | 6e-54 | 45.64% (241) | hypothetical protein MMAR_4567 |
| M. avium 104 | MAV_4067 | - | 5e-65 | 49.80% (249) | stas domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5551 | - | 3e-62 | 51.72% (232) | stas domain-containing protein |
| M. thermoresistible (build 8) | TH_3936 | - | 7e-19 | 47.17% (106) | PUTATIVE putative AMP-dependent synthetase and ligase |
| M. ulcerans Agy99 | MUL_4427 | - | 5e-54 | 45.64% (241) | hypothetical protein MUL_4427 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3207|M.vanbaalenii_PYR-1 MRRWPPKPRKHSPCCGSGSPSPSPRRARPTMVDRTHVHVSASRSLDGCAM
Mflv_3450|M.gilvum_PYR-GCK ------------------------------------MQVSATPGPGGGTA
MAV_4067|M.avium_104 -----------------------------MNEQRSAVQIASEQDRD-VPV
MSMEG_5551|M.smegmatis_MC2_155 -----------------------------MTRSRSPITISVT-SRGEITL
TH_3936|M.thermoresistible__bu --------------------------------------------------
Mb0966c|M.bovis_AF2122/97 ------------------------MVAVSTAAKSPTALAIAVRTQDSVVI
Rv0941c|M.tuberculosis_H37Rv ------------------------MVAVSTAAKSPTALAIAVRTQDSVVI
MMAR_4567|M.marinum_M ---------------------------MNATAKSPNALAIDTRSEDSLVV
MUL_4427|M.ulcerans_Agy99 ---------------------------MNATAKSPNALAIDTRSEDSLVV
Mvan_3207|M.vanbaalenii_PYR-1 LVLSGTLDSWTYREVRNSVIKAALDEPKAVVVDVSDLHVPASSAWTAFTS
Mflv_3450|M.gilvum_PYR-GCK LTITGTLDGSTYHEVRDSIIKAALEEPDAVIVDVSGLEVPSESAWKAITS
MAV_4067|M.avium_104 LTVDGVLDSSTYRTVRDTVIKAAIDEPRAVVVDVDRVRAPSASAWTVFTS
MSMEG_5551|M.smegmatis_MC2_155 LTVDGVLDSTTYREVRDTVIKAALSEPRAVVVNVSRLVVPTETAWSVFTS
TH_3936|M.thermoresistible__bu --------------------------------------------------
Mb0966c|M.bovis_AF2122/97 LTADGALDSSSSALLRDSLTRATLEQPSAVIVNVTELQVAEESAWSVFIS
Rv0941c|M.tuberculosis_H37Rv LTADGALDSSSSALLRDSLTRATLEQPSAVIVNVTELQVAEESAWSVFIS
MMAR_4567|M.marinum_M LSVEGAIDSTNCAALRDAIIKATLDEPSAVVVNVSALQVPDEASWSIFVS
MUL_4427|M.ulcerans_Agy99 LSVEGAIDSTNCAALRDAIIKATLDEPSAVVVNVSALQVPDEASWSIFVS
Mvan_3207|M.vanbaalenii_PYR-1 ARWHVSTWPDVPIVLVCAQEERRAAIQRSGASRWVPVHPDEASAAASIG-
Mflv_3450|M.gilvum_PYR-GCK AHWHVRRWPHVPILLVCDEPARRAAITRSGVTRHVRLHPDHTSAARCVA-
MAV_4067|M.avium_104 ARWHVSIWPDVPILLVCAHPQTRREITTAGVTRYVPVHPTRELAVRAVHG
MSMEG_5551|M.smegmatis_MC2_155 ARWHVCVWPDVPVLLVCDHQQGRASLWRNGIQRYVPVCSTLDEACATVLA
TH_3936|M.thermoresistible__bu --------------------------------------------------
Mb0966c|M.bovis_AF2122/97 ARWQADFRADVPVLLVCGHRAGRAAVTRTGVARFMPVYPTEKAASKAIGR
Rv0941c|M.tuberculosis_H37Rv ARWQADFRADVPVLLVCGHRAGRAAVTRTGVARFMPVYPTEKAASKAIGR
MMAR_4567|M.marinum_M ARWQVDTPQHVPILLVCASRAGRELITRTGVTRFMPVYPTEKGAIKAVGR
MUL_4427|M.ulcerans_Agy99 ARWQVDTPQHVPILLVCASRAGRELITRTGVTRFMPVYPTEKRAIKAVGR
Mvan_3207|M.vanbaalenii_PYR-1 -EPHRLRRRARDELAADRSSLTRARGLVARWLTEWACPDLILAASTVATV
Mflv_3450|M.gilvum_PYR-GCK -APTWMRRRADVELDAGADCLQVMREVLARRLSEWGRPDMTLAASTVATV
MAV_4067|M.avium_104 -RTLQVRRRARTELPRSDTSLHLARAVLTDWLTQWDIREVIPVAATVVTV
MSMEG_5551|M.smegmatis_MC2_155 DRMSPLRRRARAHLPAVHSSVRRSRELVTDWLLNWSLTKYIPVTCVVTDA
TH_3936|M.thermoresistible__bu ---------------------------VADVLARWSQEELIGVAKVVITT
Mb0966c|M.bovis_AF2122/97 LARRNFKR-SDAQLPANLNSLRESRQLVREWLTQWSRPGLIPVALVVVNV
Rv0941c|M.tuberculosis_H37Rv LARRNFKR-SDAQLPANLNSLRESRQLVREWLTQWSRPGLIPVALVVVNV
MMAR_4567|M.marinum_M LARRKVRY-AQVQLPANLGSLRESRKLVREWLTSWSKPGLIPVALVIVNV
MUL_4427|M.ulcerans_Agy99 LARRKVRY-AQVQLPANLGSLRESRKLVREWLTSWSKPGLIPVALVIVNV
: * * .: .: .
Mvan_3207|M.vanbaalenii_PYR-1 LIENVLEHTSSRPILVLEAFDGCVTVAVSDQCPTPAALHESSGSGAHTVS
Mflv_3450|M.gilvum_PYR-GCK LVENVLEHTESRPTLIVETAGDFVAVAVSDENRIPPARREDPGTGAHTVS
MAV_4067|M.avium_104 FVENVLDHTESAPVLIVESHRDTVTVAVEDNSFALPGRHEDADRGADIVS
MSMEG_5551|M.smegmatis_MC2_155 LVENVLEHTLSAPKIMLENRGDTVSIAVEDESPAPAVRHEDPYRGGGRLS
TH_3936|M.thermoresistible__bu FVENVLVHTDSAPGVRLETDGQTVTVAVEDDDPAPPTLREDR-EAAAAPA
Mb0966c|M.bovis_AF2122/97 FVENVLKHTGSDPVMRIESDGPTATIAVSDGSSAPAVRLASPPKGID-VS
Rv0941c|M.tuberculosis_H37Rv FVENVLKHTGSDPVMRIESDGPTATIAVSDGSSAPAVRLASPPKGID-VS
MMAR_4567|M.marinum_M FVENVLEHTGSDPVIKVQCDGTAATIAVSDGSNAPAIRLQTPPKGID-VS
MUL_4427|M.ulcerans_Agy99 FVENVLEHTGSDPVIKVQCDGTAATIAVSDGSNAPAIRLQTPPKGID-VS
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Mvan_3207|M.vanbaalenii_PYR-1 GLAIVATLSRSWGSIPTANGKTVWTVLGPESRL
Mflv_3450|M.gilvum_PYR-GCK DLAIVTALSHAWGCTPTTTGKTVWALLAPENQF
MAV_4067|M.avium_104 GLAIVSALCRVWGATPTSSGKTVWGSVGREDRI
MSMEG_5551|M.smegmatis_MC2_155 GLALVASIARSWGCTPTTTGKTVWALIGPESCF
TH_3936|M.thermoresistible__bu GLHTVARLVRAWGTAPSPAGKTVWAVLGPENRI
Mb0966c|M.bovis_AF2122/97 GLAIVAALSRAWGSSPTSSGKTVWAIIGPENQL
Rv0941c|M.tuberculosis_H37Rv GLAIVAALSRAWGSSPTSSGKTVWAIIGPENQL
MMAR_4567|M.marinum_M GLAIVEALCRAWGSTPTATGKTVWAIIGPENQL
MUL_4427|M.ulcerans_Agy99 GLAIVEALCRAWGSTPTATGKTVWAIIGPENQL
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