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VTTVLVGQPVGADEVVADYLDHVATLGLSGRAVRDRIRIARDFTARHRDLHAWMTLPAAERIAEIRDTGA WPLICHTIGTGRLRLDVELAAVKQLTGLGRAVEDRDPSGFATLRNAGIRLGWRSSWVETVLGECLAVVLA HHGGMVADLTGDALDDFDATLSRTAVPPSSRRAYRARLASLRQLLFETAVIDTAPKRRRWARSHEQRFTE VEMPDPIRQTLLRYIGVRAAVLRPKSVESLINDLLPFAEYLTAHHPDLTSLRGLDRSCIEGYLKWNRTRG WRGQRAAAGAGRTVSAAVAQSAVLSLRNLLDDITAWGWAQAPPRRLVFAADVPKLDQPLPRALAPDVDAA VMNAVAHLQDPFARIGLTVLRGAGLRAGELLDLELGSIIDYGPAGTWLKVPLGKLATERMVPLSAATLAA LDEWVALRGTHRPLPHPRTGVLTDFLFTRHGRRLGYTRLRNGLLTAAESAGLHRPDGGVLMVTPHQLRHT WATELANAGMSLQALMSLLGHVTPQMTIRYATLASPTLRAAYDEAMGKMRRQFTLTPVGKPILPDKVGWL HSEMLKTRVAHGYCARHESAGACPYANICETCDNYITAPEFRDTLTNQLADVQDLRTDAECRGWTDEAAR HDRVAHALTDHLHRLDH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5498 | - | - | 100% (647) | phage integrase family protein |
M. vanbaalenii PYR-1 | Mvan_3588 | - | 0.0 | 100.00% (647) | phage integrase family protein |
M. vanbaalenii PYR-1 | Mvan_0456 | - | 0.0 | 100.00% (647) | phage integrase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2918c | xerC | 5e-14 | 31.33% (300) | site-specific tyrosine recombinase XerC |
M. gilvum PYR-GCK | Mflv_4644 | - | 2e-94 | 36.22% (635) | phage integrase family protein |
M. tuberculosis H37Rv | Rv2894c | xerC | 5e-14 | 31.33% (300) | site-specific tyrosine recombinase XerC |
M. leprae Br4923 | MLBr_01600 | xerC | 2e-12 | 31.39% (274) | site-specific tyrosine recombinase XerC |
M. abscessus ATCC 19977 | MAB_3204c | xerC | 2e-15 | 29.33% (300) | site-specific tyrosine recombinase XerC |
M. marinum M | MMAR_1817 | xerC | 7e-15 | 30.55% (311) | integrase/recombinase XerC |
M. avium 104 | MAV_3746 | xerC | 9e-15 | 32.84% (271) | site-specific tyrosine recombinase XerC |
M. smegmatis MC2 155 | MSMEG_4156 | - | 1e-21 | 26.80% (403) | putative transposase |
M. thermoresistible (build 8) | TH_3747 | - | 0.0 | 74.49% (635) | PUTATIVE phage integrase family protein |
M. ulcerans Agy99 | MUL_2065 | xerC | 5e-15 | 30.55% (311) | site-specific tyrosine recombinase XerC |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_5498|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_3747|M.thermoresistible__bu -------------------------------------------------- Mflv_4644|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1817|M.marinum_M -------------------------------------------------- MUL_2065|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01600|M.leprae_Br4923 -------------------------------------------------- Mb2918c|M.bovis_AF2122/97 -------------------------------------------------- Rv2894c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3746|M.avium_104 -------------------------------------------------- MAB_3204c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_4156|M.smegmatis_MC2_155 MTALDPNSTLGLLGRLMAGVRSEFRRDVLEFAADDAVFGGGSCRVTDCGR Mvan_5498|M.vanbaalenii_PYR-1 --------------------------MTT---VLVGQPVGADEVVADYLD TH_3747|M.thermoresistible__bu --------------------------MTTPALAMVDPLADPDTVLADYLE Mflv_4644|M.gilvum_PYR-GCK --------------------------MLP----EHDYAPTPETPAQIYAA MMAR_1817|M.marinum_M -------------------------------------------------- MUL_2065|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01600|M.leprae_Br4923 -------------------------------------------------- Mb2918c|M.bovis_AF2122/97 -------------------------------------------------- Rv2894c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3746|M.avium_104 -------------------------------------------------- MAB_3204c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_4156|M.smegmatis_MC2_155 SARGHGLCQGHHQRWANAGRPDLEEFTVSTDPRWRKHRPNQACRVDGCGY Mvan_5498|M.vanbaalenii_PYR-1 HVATLGLSGRAVRDRIRIARDFTARHRDLHAWMTLPAAERIAEIRDTGAW TH_3747|M.thermoresistible__bu YVAALGLSGRSVRARTLIATTFLTSHPDLRDWMTRPAAERLIELRRTGAW Mflv_4644|M.gilvum_PYR-GCK YLVHLQRRDRGNTAYAQAARSFLRRWPRVQSWADIPLDEQLAANCST--R MMAR_1817|M.marinum_M -------------------------------------------------- MUL_2065|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01600|M.leprae_Br4923 -------------------------------------------------- Mb2918c|M.bovis_AF2122/97 -------------------------------------------------- Rv2894c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3746|M.avium_104 -------------------------------------------------- MAB_3204c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_4156|M.smegmatis_MC2_155 GSARGGLCQLHAQRWERAGRPHLASWLRDPLPVKQPRPGATCRIRHCSLW Mvan_5498|M.vanbaalenii_PYR-1 PLICHTIGTGRLRLDVELAAVKQLTGLGRAVEDRDPS-GFATLRNAGIRL TH_3747|M.thermoresistible__bu PLLCHLIGRGELRLDLELAAVKNLTGLGRAVEDRDPD-GFAAVRAAGLAL Mflv_4644|M.gilvum_PYR-GCK PFVTFLMVSRRLQPGYDYLVHRKLSSLWHELTDSCLQPDLDQFISAALEL MMAR_1817|M.marinum_M -------------------------------------------------- MUL_2065|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01600|M.leprae_Br4923 -------------------------------------------------- Mb2918c|M.bovis_AF2122/97 -------------------------------------------------- Rv2894c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3746|M.avium_104 -------------------------------------------------- MAB_3204c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_4156|M.smegmatis_MC2_155 PQAESPLCHSHTNTWKANGRTDIDGFVTRFESNDTPANETIQLGMLTPQL Mvan_5498|M.vanbaalenii_PYR-1 GWRSSWVETV-----LGECLAVVLAHHGGMVADLTGDALDDFDATLSRT- TH_3747|M.thermoresistible__bu GWTPQWIETV-----LGECLAVLLAWHGGLVSGVSADTVDEFDAALAATQ Mflv_4644|M.gilvum_PYR-GCK GFTERVASAI-----GSQIIARLLIQTGRPLTGLRESDLQELLHACHVRQ MMAR_1817|M.marinum_M ------------------------------MPDNSEAILEEFDEYLALQC MUL_2065|M.ulcerans_Agy99 ------------------------------MPDNSEAILEEFDEYLALQC MLBr_01600|M.leprae_Br4923 -----------------------------------MAILDEFDEHLALRC Mb2918c|M.bovis_AF2122/97 ----------------------------------MQAILDEFDEYLALQC Rv2894c|M.tuberculosis_H37Rv ----------------------------------MQAILDEFDEYLALQC MAV_3746|M.avium_104 -------------------------------MPDSEPILEEFDEYLALQC MAB_3204c|M.abscessus_ATCC_199 ------------------------------MTPQLAAILDEFAEHLALER MSMEG_4156|M.smegmatis_MC2_155 KLEMQYVLQQRHDDRRGKLTPTVVARVVRLLIDTATTSLLDFDADEWRQR : :: Mvan_5498|M.vanbaalenii_PYR-1 AVPPSSRRAYRARLASLRQLLFETAVIDTAPKRRRWARSHEQRFTEVEMP TH_3747|M.thermoresistible__bu SIPATSRRAYRNRIAGLRQMLFQARIVDTPPRRRRWARSYAQRFAEVPMA Mflv_4644|M.gilvum_PYR-GCK ERTGRGAKHYRSTTHSARQILFHLGILDTQARPAVTALTLEQRMVDVPVA MMAR_1817|M.marinum_M GRSAHTRRAYLGDLR----------------------------------- MUL_2065|M.ulcerans_Agy99 GRSAHTRRAYLGDLR----------------------------------- MLBr_01600|M.leprae_Br4923 GRSEHTRRAYLGDLR----------------------------------- Mb2918c|M.bovis_AF2122/97 GRSVHTRRAYLGDLR----------------------------------- Rv2894c|M.tuberculosis_H37Rv GRSVHTRRAYLGDLR----------------------------------- MAV_3746|M.avium_104 GRSAHTRRAYLGDLR----------------------------------- MAB_3204c|M.abscessus_ATCC_199 GRSVHTQRAYRGDLT----------------------------------- MSMEG_4156|M.smegmatis_MC2_155 SAVLLNDTRSRGLLLYAHSTVLDLAEAGG------WEAEYPRDVWRMHRL Mvan_5498|M.vanbaalenii_PYR-1 DPIRQTLLRYIGVRAAVLRPKSVESLINDLLPFAEYLTAHHPDLTSLRGL TH_3747|M.thermoresistible__bu DAIRATLLRYVTVRASVLRPKSVESLINDLLPFADYLTTAHPEVTSLEDL Mflv_4644|M.gilvum_PYR-GCK --LRPAFVAYLNRKYATCVPKTVSSLATRLAHFGRYLAAADPSLTSLNQL MMAR_1817|M.marinum_M -----SLLDYLAGRG--ADLRALS-----LPVLRSWLATAAGAGAARTTL MUL_2065|M.ulcerans_Agy99 -----SLLDYLAGRG--ADLRALS-----LPVLRSWLATAAGAGAARTTL MLBr_01600|M.leprae_Br4923 -----SLLTHLEGRG--SRLDQLS-----LPVLRSWLATAAGAGAARTTL Mb2918c|M.bovis_AF2122/97 -----SLFAFLADRG--SSLDALT-----LSVLRSWLAATAGAGAARTTL Rv2894c|M.tuberculosis_H37Rv -----SLFAFLADRG--SSLDALT-----LSVLRSWLAATAGAGAARTTL MAV_3746|M.avium_104 -----SLLAFAGERG--TGLDGLS-----LPLLRSWLSAAAAGGVARTTL MAB_3204c|M.abscessus_ATCC_199 -----LLFDHLSASNPEATLADLS-----LPVLRSWLGAQARQGAARSTV MSMEG_4156|M.smegmatis_MC2_155 GYEGHYTLRFDRIPQPWLREPAKRWIRLRLSRGLNLEAGGGRPLLAIARF . . * : . Mvan_5498|M.vanbaalenii_PYR-1 DRS-CIEGYLKWNRTRGWRGQRAAAGAGRTVSAAVAQSAVLSLRNLLDDI TH_3747|M.thermoresistible__bu DRN-HIEGFLVWNRTRTWRGQRAASGAGRIISKAVIQSTVLSVRNLLDDI Mflv_4644|M.gilvum_PYR-GCK DRRRHIEPFITSLTTATN------SVTGEPITVADRIRCIHAVGNFLAEI MMAR_1817|M.marinum_M ARR------------------------------------TSAVKAFTAWA MUL_2065|M.ulcerans_Agy99 ARR------------------------------------TSAVKAFTAWA MLBr_01600|M.leprae_Br4923 ARR------------------------------------ISAVKAFTAWA Mb2918c|M.bovis_AF2122/97 ARR------------------------------------TSAVKAFTAWA Rv2894c|M.tuberculosis_H37Rv ARR------------------------------------TSAVKAFTAWA MAV_3746|M.avium_104 ARR------------------------------------TSAVKAFTAWA MAB_3204c|M.abscessus_ATCC_199 ARR------------------------------------TSAVKIFTAWA MSMEG_4156|M.smegmatis_MC2_155 GRFLAEVDIEDISRIDRELLERYLAHLNREYSPQRRGAHIGLLNGFFAAI * : : Mvan_5498|M.vanbaalenii_PYR-1 TAWGWAQAPPRRLVFAADVPKLDQPLPRALAPDVDAAVMNAVAHLQDP-- TH_3747|M.thermoresistible__bu TEWGWEQAPPRRLVFAVDVPKLDQPLPRALPPDIDVAVMNAVSGLDDS-- Mflv_4644|M.gilvum_PYR-GCK TEWGWDDAPPRRLIFRTDLPRPPRCLPRYLPVDSDRKLTAALAKSPYR-- MMAR_1817|M.marinum_M VRRGLLATDP---AARLQVPKAHRTLPAVLRQDQALAAMTAAKSGAQQGD MUL_2065|M.ulcerans_Agy99 VRRGLLATDP---AARLQVPKAHRTLPAVLRQDQALAAMTAAKSSAQQGD MLBr_01600|M.leprae_Br4923 KWRGQLAADP---AARLQVPRAYRTLPAVLRQDQALQIMAAAKSGAEQGD Mb2918c|M.bovis_AF2122/97 VRRGLLAGDP---AARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGD Rv2894c|M.tuberculosis_H37Rv VRRGLLAGDP---AARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGD MAV_3746|M.avium_104 VRRGLLTADP---AARLQVPKTHRTLPAVLRQDQALGAMAAAKNGAAQGD MAB_3204c|M.abscessus_ATCC_199 TRRGLLPTDP---AIRLQQPKSRRTLPAVLRQDQAAAAMEAAHSGAEQDD MSMEG_4156|M.smegmatis_MC2_155 RQHCWATGLP---ATAMFFAEDHPKRGEHLPRALAEHVMTQLEHRDNLDR * .. * Mvan_5498|M.vanbaalenii_PYR-1 ----FARIGLTVLRGAGLRAGELLDLELGSIIDYGPAGTWLKVPLGKLAT TH_3747|M.thermoresistible__bu ----FARIGLTVLRGAGLRVGELLDLELGSVIDYGPAGTWLKVPLGKLAT Mflv_4644|M.gilvum_PYR-GCK ----LAADALLVQRACGLRIGELLDLELDCIHEIPGQGSWLKVPLGKLNS MMAR_1817|M.marinum_M PLALRDRLIVELLYATGIRVSELCGLDIDDVD----TGHRLVRVLGKGNK MUL_2065|M.ulcerans_Agy99 PLALRDRLIVELLYATGIRVSELRGLDIDDVD----TGHRLVRVLGKGNK MLBr_01600|M.leprae_Br4923 PLALRDRLIVEMLYATGIRVSELCGLDIDDVD----TRHRLVRVLGKGNK Mb2918c|M.bovis_AF2122/97 PLALRDRLIVELLYATGIRVSELCGLDVDDID----TGHRLVRVLGKGNK Rv2894c|M.tuberculosis_H37Rv PLALRDRLIVELLYATGIRVSELCGLDVDDID----TGHRLVRVLGKGNK MAV_3746|M.avium_104 PIALRDRLIVEMLYATGIRVSELCGLDIDDVD----TGRRLVRVLGKGNK MAB_3204c|M.abscessus_ATCC_199 PMALRDRLIVEMLYATGIRVSELCGLDIDDID----RPRKVLRVLGKGDK MSMEG_4156|M.smegmatis_MC2_155 FNNPVYRLITVILMRCGLRITDALRLRGDCVTTDANGAPYLRYFNHKMKR : *:* : * . : : * Mvan_5498|M.vanbaalenii_PYR-1 ERMVPLSAATLAALDEWVALRGTHRPLPHPRTGVLTDFLFTRHGRRLG-- TH_3747|M.thermoresistible__bu ERMVPLSVATIAALDEWTTGRGICRPLPHPRTGALTDFLFVAHGRRLS-- Mflv_4644|M.gilvum_PYR-GCK ERMIPVDDEVLTLVDRITTTRSSGRPMIHPRTGAPADFLFTHHGKRLS-- MMAR_1817|M.marinum_M QRTAPFGQPAAEALQAWLADGR--PALATAESGP--ALLLGARGRRLD-- MUL_2065|M.ulcerans_Agy99 QRTAPFGQPAAEALQAWLADGR--PALATAESGP--ALLLGARGRRLD-- MLBr_01600|M.leprae_Br4923 QRTAPFGVPAADALRGWLDDGR--PALVTVESGP--ALLLGSRGRRLD-- Mb2918c|M.bovis_AF2122/97 QRTVPFGQPAADALHAWLVDGR--RALVTAESGH--ALLLGARGRRLD-- Rv2894c|M.tuberculosis_H37Rv QRTVPFGQPAADALHAWLVDGR--RALVTAESGH--ALLLGARGRRLD-- MAV_3746|M.avium_104 QRSVPFGAPAGEALHAWLADGR--PALANAESGP--ALLLGARGRRLD-- MAB_3204c|M.abscessus_ATCC_199 ERTVPFGDPAADALSAWLDRGR--PHLAVPASGA--ALLLGARGRRVD-- MSMEG_4156|M.smegmatis_MC2_155 DALVPIAPDLVDMIGYQR-------RLVSERWPDGTALLFPRPTKNIDGQ : *. : : :*: :.:. Mvan_5498|M.vanbaalenii_PYR-1 ----YTRLRNGLLTAAESAGLHRPDGGVLMVTPHQLRHTWATELANAGMS TH_3747|M.thermoresistible__bu ----QTRLRNGLIAAVETCGLRGAGGAPLVVTPHQLRHTWATELANAGMG Mflv_4644|M.gilvum_PYR-GCK ----QNAVREELNRAAQAASLG-------HITPHQLRHTYATALINAGVS MMAR_1817|M.marinum_M ----VRQARTVVHQTVAAVDGAP------DMGPHGLRHSAATHLLEGGAD MUL_2065|M.ulcerans_Agy99 ----VRQARTVVHQTIAAVDGAP------DMGPHGLRHSAATHLLEGGAD MLBr_01600|M.leprae_Br4923 ----VRQARTVVHQTVAVVAGAP------DMGPHGLRHSAATHLLEGGAD Mb2918c|M.bovis_AF2122/97 ----VRQARTAVHQTVAAVDGAP------DMGPHGLRHSAATHLLEGGAD Rv2894c|M.tuberculosis_H37Rv ----VRQARTAVHQTVAAVDGAP------DMGPHGLRHSAATHLLEGGAD MAV_3746|M.avium_104 ----VRQARTVVHQTIAAVSGAP------DMGPHGLRHSAATHLLEGGAD MAB_3204c|M.abscessus_ATCC_199 ----PRQVRTVVHQTMSAVPGAP------DIGPHGLRHSAATHLLEGGAD MSMEG_4156|M.smegmatis_MC2_155 IPLAIPTYREALHRWLAVCDIRDEHSDPVHLTPHQWRHTLGTRLINRDVP * : : ** **: .* * : . Mvan_5498|M.vanbaalenii_PYR-1 LQALMSLLGHVTPQMTIRYATLASPTLRAAYDEAMGKMR---RQFTLTPV TH_3747|M.thermoresistible__bu LQALMALLGHVTPQMTLRYATLASPTLRDAYDQAMGKMR---RRFTLTPV Mflv_4644|M.gilvum_PYR-GCK LQALMALLGHVSTQMSLRYAHLFDHTVRTEYERALDLAKSHIGALPKTAV MMAR_1817|M.marinum_M LRVVQELLGHSSLATTQLYTHVAVSRLRAVHDQAHPRA------------ MUL_2065|M.ulcerans_Agy99 LRVVQELLGHSSLATTQLYTHVAVSRLRAVHDQAHPRA------------ MLBr_01600|M.leprae_Br4923 LRVVQELLGHSSLATTQLYTHVAVSRLRVVHDQAHPRA------------ Mb2918c|M.bovis_AF2122/97 LRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA------------ Rv2894c|M.tuberculosis_H37Rv LRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA------------ MAV_3746|M.avium_104 LRVVQELLGHSSLATTQLYTHVAVSRLRAVHDQAHPRA------------ MAB_3204c|M.abscessus_ATCC_199 LRVVQELLGHSTLATTQLYTHVTVARLRAVHDQAHPRA------------ MSMEG_4156|M.smegmatis_MC2_155 QEVVRRILDHDSPQMTAHYARLHDTTVRRAWEAAR-KVDSHGREVNLDPD ..: :*.* : : *: : :* : * Mvan_5498|M.vanbaalenii_PYR-1 GKPILPDK-VGWLHSEMLKTRVAHGYCARHESAGACPYANICETCDNYIT TH_3747|M.thermoresistible__bu GKPIVPDA-VIWLGSEMLKTRVAHGYCSRHESAGACPYANICETCDNFVT Mflv_4644|M.gilvum_PYR-GCK GLPITDITGTGWKDTPAIKSRLAGGYCLRAPAQGSCPYANICEHCPSFHT MMAR_1817|M.marinum_M -------------------------------------------------- MUL_2065|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01600|M.leprae_Br4923 -------------------------------------------------- Mb2918c|M.bovis_AF2122/97 -------------------------------------------------- Rv2894c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3746|M.avium_104 -------------------------------------------------- MAB_3204c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_4156|M.smegmatis_MC2_155 GP--LAEAAWAKQRLGRATQALPNGYCG-LPVQQSCPHANACLTCPMFLT Mvan_5498|M.vanbaalenii_PYR-1 APEFRDTLTNQLADVQDLRTDAECRGWTDEAARHDRVAHALTDHLHRLDH TH_3747|M.thermoresistible__bu GPEFRDALEAQRTDVEALEVDARDRGWPDEAARHHRVADALTDHLQRLDR Mflv_4644|M.gilvum_PYR-GCK DSTHLAVLAAQRIDAQDLAADAEKRGWIDEAERHHNLVSRLDALITGSAS MMAR_1817|M.marinum_M -------------------------------------------------- MUL_2065|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01600|M.leprae_Br4923 -------------------------------------------------- Mb2918c|M.bovis_AF2122/97 -------------------------------------------------- Rv2894c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3746|M.avium_104 -------------------------------------------------- MAB_3204c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_4156|M.smegmatis_MC2_155 TQEFLPQHRTQREQTLHLITAAEARGHQRLAEMNRQVLGNLDAIITSLDT Mvan_5498|M.vanbaalenii_PYR-1 ----------- TH_3747|M.thermoresistible__bu ----------- Mflv_4644|M.gilvum_PYR-GCK A---------- MMAR_1817|M.marinum_M ----------- MUL_2065|M.ulcerans_Agy99 ----------- MLBr_01600|M.leprae_Br4923 ----------- Mb2918c|M.bovis_AF2122/97 ----------- Rv2894c|M.tuberculosis_H37Rv ----------- MAV_3746|M.avium_104 ----------- MAB_3204c|M.abscessus_ATCC_199 ----------- MSMEG_4156|M.smegmatis_MC2_155 PTDPKAAEHAS