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M. thermoresistible (build 8) TH_3592 (-)

annotation: AAA ATPase, central domain protein
coordinates: 4438899 - 4440620
length: 574

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3592--100% (574)AAA ATPase, central domain protein
M. thermoresistible (build 8)TH_1380-1e-8942.18% (486) ATPase, AAA family protein
M. thermoresistible (build 8)TH_2346clpC6e-0524.29% (317) PROBABLE ATP-DEPENDENT PROTEASE ATP-BINDING SUBUNIT CLPC1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3898-0.078.71% (573) hypothetical protein Mb3898
M. gilvum PYR-GCKMflv_0773-0.081.15% (573) ATPase central domain-containing protein
M. tuberculosis H37RvRv3868-0.078.88% (573) hypothetical protein Rv3868
M. leprae Br4923MLBr_00055-0.078.71% (573) hypothetical protein MLBr_00055
M. abscessus ATCC 19977MAB_2234c-4e-8435.70% (563) hypothetical protein MAB_2234c
M. marinum MMMAR_5443-0.078.01% (573) hypothetical protein MMAR_5443
M. avium 104MAV_4871-3e-9038.45% (567) ATPase, AAA family protein
M. smegmatis MC2 155MSMEG_0059-0.083.45% (574) ATPase, AAA family protein
M. ulcerans Agy99MUL_1204-2e-8337.43% (569) hypothetical protein MUL_1204
M. vanbaalenii PYR-1Mvan_0072-0.082.37% (573) ATPase central domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3592|M.thermoresistible__bu      ----------------------MSDHLASLFGS---AVGMLPSAPERSLE
MSMEG_0059|M.smegmatis_MC2_155      ----------------------MVNHLAGMFGS---AVGMMSNSRARALE
Mflv_0773|M.gilvum_PYR-GCK          ----------------------MTEHLASVFGT---AVGLLPTAQAKSLE
Mvan_0072|M.vanbaalenii_PYR-1       ----------------------MTDHLASVFGT---AVGLLPTSQARSLE
Mb3898|M.bovis_AF2122/97            ----------------------MTDRLASLFES---AVSMLPMSEARSLD
Rv3868|M.tuberculosis_H37Rv         ----------------------MTDRLASLFES---AVSMLPMSEARSLD
MLBr_00055|M.leprae_Br4923          ----------------------MIDRLGSLFES---AASMLPMSEARSFE
MMAR_5443|M.marinum_M               ----------------------MTDRLAGLFES---AVSMLPLSESRSMD
MAV_4871|M.avium_104                MERGD-TGMLTAQPVNSRVDARVDGDVVSRFATCCRALGIVVYQRQRPAD
MUL_1204|M.ulcerans_Agy99           MKRGD-IGMPAAQSPTSRVSGRVDADVVSRFATCCRALGIAVYDRKRPAD
MAB_2234c|M.abscessus_ATCC_199      MDIRERVGQRGWAAQDVASATRIDPELESRFATCCRALGLSVNDRRRPAD
                                                          :   : . * :   * .:      :. :

TH_3592|M.thermoresistible__bu      L------FTEITNYDESACDAWVGRIRCGDTDRVTLFRAWYSRTNFGQLA
MSMEG_0059|M.smegmatis_MC2_155      I------FTEITNYDESACDAWVGRIGCGDTDRVTLFRAWYSRSNFGQLA
Mflv_0773|M.gilvum_PYR-GCK          L------FTEITTLDETACDAWVGRIRCGDTDRVTMFRAWYSRNNFGQLA
Mvan_0072|M.vanbaalenii_PYR-1       L------FTEITTLDESACDAWVGRIRCGDTDRVTMFRAWYSRNNFGQLA
Mb3898|M.bovis_AF2122/97            L------FTEITNYDESACDAWIGRIRCGDTDRVTLFRAWYSRRNFGQLS
Rv3868|M.tuberculosis_H37Rv         L------FTEITNYDESACDAWIGRIRCGDTDRVTLFRAWYSRRNFGQLS
MLBr_00055|M.leprae_Br4923          L------FTEITNYDETACDAWIGRIRCGDTDRVTLFRAWYSRRNFGQLS
MMAR_5443|M.marinum_M               L------FTEITNYDESACDAWVGRIRCGDVDRVTLFRAWYSRRNFGQLA
MAV_4871|M.avium_104                LAAARSGFAALTRIAHDQCDAWTGLAAAGDVSLRVLEAVARTAATAGVLQ
MUL_1204|M.ulcerans_Agy99           LDAARSGFGALTRVASDQCDAWTGLAAAGDQSIGVLEAVLRTAGTAGTLQ
MAB_2234c|M.abscessus_ATCC_199      LPAARYGFTSLCRTAQDQCDVWVGLAAAGGATVDVLEAISETTATAGHLQ
                                    :      *  :       **.* *   .*.    .:     :  . * * 

TH_3592|M.thermoresistible__bu      GAAEISMNSVNARIPIGGLFG-DITYPINSPLAITMGFAVNEAAEGN---
MSMEG_0059|M.smegmatis_MC2_155      GAAEISMNGVGARIPIGGIYSRDITYPINSPLAITMGFAVHEASEGN---
Mflv_0773|M.gilvum_PYR-GCK          SAAEMSMNSLGARVPIGGMFG-DITYPVNSPLAITLSFAVSEAAVGN---
Mvan_0072|M.vanbaalenii_PYR-1       GTAEISMNSLGARVPIGGMYG-DITYPVNSPLAITLGFAVSEAALGN---
Mb3898|M.bovis_AF2122/97            GSVQISMSTLNARIAIGGLYG-DITYPVTSPLAITMGFAACEAAQGN---
Rv3868|M.tuberculosis_H37Rv         GSVQISMSTLNARIAIGGLYG-DITYPVTSPLAITMGFAACEAAQGN---
MLBr_00055|M.leprae_Br4923          GSVQIPMTTLNARVPIGGLYG-DITYPVTSPLAITMGFAACEAAQGN---
MMAR_5443|M.marinum_M               GTAQISMSTLNARVPIGGLYG-DITYPVTSPLAITMGFAASEAAQGN---
MAV_4871|M.avium_104                RQVDLAPGALGFRYDTG-LYL---QFRATTTDDFQLAYAAALATAGR---
MUL_1204|M.ulcerans_Agy99           RHVELAAGSLGFLYDTG-LYL---RFRATDPDGFHLAYAAALALAGESAQ
MAB_2234c|M.abscessus_ATCC_199      HAVNLHPGDLTFTYDTG-LYL---EFRAGGPDDYHLAYAAALVDKGE---
                                      .::    :      * ::     :    .    :.:*.  .  *.   

TH_3592|M.thermoresistible__bu      YADAMEALEEVQANG-AEHLVAWVKAVIYAAAERWTDVIDEVRGASG--W
MSMEG_0059|M.smegmatis_MC2_155      YTDAMEALEDAPAAG-SEHLVSWVRAVIYGAGQRWTEVIDQVRGAER--W
Mflv_0773|M.gilvum_PYR-GCK          YADAIEALEAAPAAG-GEHLVSWVKAVIYAAAERWTDVIDEVRTAATS-W
Mvan_0072|M.vanbaalenii_PYR-1       YADAMEALDEAQAAG-GEHLVSWVKAVVYGAAQRWTDVIEEVRTAGAG-W
Mb3898|M.bovis_AF2122/97            YADAMEALEAAPVAG-SEHLVAWMKAVVYGAAERWTDVIDQVKSAGK--W
Rv3868|M.tuberculosis_H37Rv         YADAMEALEAAPVAG-SEHLVAWMKAVVYGAAERWTDVIDQVKSAGK--W
MLBr_00055|M.leprae_Br4923          FADAMEAIDATSITG-SEHLVAWLKAVVYGAAERWTDVIDEVKGAGK--W
MMAR_5443|M.marinum_M               YADAMEAIDAGAVTG-SEHLVSWLKAVIFGAAERWTDVIDEVKGAGK--W
MAV_4871|M.avium_104                FADADRIVAALTAARPGWREARWVSVVINYRAERWSDVVKLLTPIVNDTD
MUL_1204|M.ulcerans_Agy99           FAKANELVSGIVDRRPSWRDARWLAVVINYRAQRWSDVVKLLTPIVNDSE
MAB_2234c|M.abscessus_ATCC_199      YDKANELIAAVTARRPGWFNARWVAVAMQNRAQRWADVVSLLTPVVTDES
                                    : .* . :        .   . *: ..:   .:**::*:. :        

TH_3592|M.thermoresistible__bu      PDKVLAAAGGVAHGVAAANLGLFTEAERRLTESNASPAGQACAPAIAWYL
MSMEG_0059|M.smegmatis_MC2_155      PDKFLAAAAGVAHGVAAANLGLFTEADRRLTEANDTPVAQACAPVIAWYL
Mflv_0773|M.gilvum_PYR-GCK          PDKFLVGAALVAHGVAAANLGLFTEAERRLVEANSGPAGQACNRVIAWYS
Mvan_0072|M.vanbaalenii_PYR-1       PDKFLAGAALVAHGVAAANLGLFTEAERRLVEANSAPAGQACNRTIAWYS
Mb3898|M.bovis_AF2122/97            PDKFLAGAAGVAHGVAAANLALFTEAERRLTEANDSPAGEACARAIAWYL
Rv3868|M.tuberculosis_H37Rv         PDKFLAGAAGVAHGVAAANLALFTEAERRLTEANDSPAGEACARAIAWYL
MLBr_00055|M.leprae_Br4923          PDKFLAGAAGVAHGVAAANLGLFTEAERRLTEANDSPAGEACARSIAWYL
MMAR_5443|M.marinum_M               PDKFLAGAASVAHGVAAASLGLFTEAERRLTEANDSPAGEACAQAIAWYL
MAV_4871|M.avium_104                LDDAYAHAAKIALGTALARLGMFAPALSYLEEPDGPVAVAAVDGALAK--
MUL_1204|M.ulcerans_Agy99           LDEAFAHAAKITLGTALARLGMFAPALSYLEEPDGPVPVAAVDGALAK--
MAB_2234c|M.abscessus_ATCC_199      LDPTTSHAVRITLGIALAKLGMVNPALSYLEDPSGPIEVAATDGALAK--
                                     *     *  :: * * * *.:.  *   * :..      *    :*   

TH_3592|M.thermoresistible__bu      AMTRRSQGNEDAAVALLEWLQATHPE-PKVAAALRDPNYRLETTTPEKIA
MSMEG_0059|M.smegmatis_MC2_155      AMARRSQGNEESAQVLLEWLQANFPE-PKVTAALRDPAYRLETTTAEKIA
Mflv_0773|M.gilvum_PYR-GCK          AMAYRGLGNEEAAVRLLEWLQASHPT-PEVAAALKDPGFRLQTTSGEKIA
Mvan_0072|M.vanbaalenii_PYR-1       AMAYRALGNEEAAVRLLEWLQASHPS-PEVAAALKDPSYRLQTTTAEKIA
Mb3898|M.bovis_AF2122/97            AMARRSQGNESAAVALLEWLQTTHPE-PKVAVALKDPSYRLKTTTAEQIA
Rv3868|M.tuberculosis_H37Rv         AMARRSQGNESAAVALLEWLQTTHPE-PKVAAALKDPSYRLKTTTAEQIA
MLBr_00055|M.leprae_Br4923          AMARRSQGNEDAAVALLEWLQTTHPE-SKVSAALKDPSYRLTTTTAEQIA
MMAR_5443|M.marinum_M               AMARRGQGNEEAAVALLEWLQTTHPA-PKVSAALKDPSYRLKTTNAEQIA
MAV_4871|M.avium_104                ALVLRAHVDEESASEVLQDLYAAHPENEQVEQALSDTSFGIVTTTAARIE
MUL_1204|M.ulcerans_Agy99           ALVLRAHVDEESASEVLQDLYAAHPENEQIEHALSDTSFGIVTTTTGQIE
MAB_2234c|M.abscessus_ATCC_199      ALNLRHHGDEETATEVLQDLYAANPENAEIEHALTDPSVGLHTTTSARIA
                                    *:  *   :*.:*  :*: * :  *   ::  ** *.   : **.  :* 

TH_3592|M.thermoresistible__bu      SRTDPWDPSSVVA-----DTSGREK---LLAEAQAELDRQIGLGRVKQQI
MSMEG_0059|M.smegmatis_MC2_155      ARSDPWDPSSVVA-----DTSARDK---LLVEAQAELDRQIGLGRVKEQI
Mflv_0773|M.gilvum_PYR-GCK          SRRDPWDPDSAEA-----DNSGRET---LLAEAQSELDRQIGLTRVKEQI
Mvan_0072|M.vanbaalenii_PYR-1       SRRDPWDPTTVEA-----DNTGREM---LLADAQAELDRQIGLTRVKDQI
Mb3898|M.bovis_AF2122/97            SRADPWDPGSVVT-----DNSGRER---LLAEAQAELDRQIGLTRVKNQI
Rv3868|M.tuberculosis_H37Rv         SRADPWDPGSVVT-----DNSGRER---LLAEAQAELDRQIGLTRVKNQI
MLBr_00055|M.leprae_Br4923          ARADPWDPSSVVT-----DNSDRDR---LLTQAQAELDRQIGLTRVKTQI
MMAR_5443|M.marinum_M               SRSDPWDPTSVVT-----DNSGREK---LLAEAQEELDRQIGLSRVKSQL
MAV_4871|M.avium_104                ARTDPWDPATEPSAEDFVDPAAHERKAVLLAEAERQLAEFIGLDEVKNQV
MUL_1204|M.ulcerans_Agy99           ARTDPWDPETEPSADDFVDPSAHERKGVLLHEAELQLAEFIGLEEVKNQV
MAB_2234c|M.abscessus_ATCC_199      ARTDPWDPETEPSEEDFIDPEAHERKAILLAEAEQQLSEFIGLEQVKDQV
                                    :* ***** :  :     *   ::    ** :*: :* . *** .** *:

TH_3592|M.thermoresistible__bu      EAYRAATQMAKLRAARGMKVAQTSKHMIFAGPPGTGKTTIARVVANILAG
MSMEG_0059|M.smegmatis_MC2_155      EAYRAATQMARIRAARGMKVAQTSKHMIFAGPPGTGKTTIARVVANILAG
Mflv_0773|M.gilvum_PYR-GCK          ERYRAATQMAKVRAARGMKVAQASKHMIFTGPPGTGKTTIARVVANILAG
Mvan_0072|M.vanbaalenii_PYR-1       ERYRAATQMAKVRAARGMKVAQASKHMIFTGPPGTGKTTIARVVANILAG
Mb3898|M.bovis_AF2122/97            ERYRAATLMARVRAAKGMKVAQPSKHMIFTGPPGTGKTTIARVVANILAG
Rv3868|M.tuberculosis_H37Rv         ERYRAATLMARVRAAKGMKVAQPSKHMIFTGPPGTGKTTIARVVANILAG
MLBr_00055|M.leprae_Br4923          ERYRAATMMAKVRAAKGMKVAQPSKHMIFTGPPGTGKTTIARVVANILAG
MMAR_5443|M.marinum_M               ERYRAATMMARIREAKGMKVAQPSKHMIFTGPPGTGKTTIARVVANMLAG
MAV_4871|M.avium_104                SRLKSSVAMELVRKQRGLAVAQRAHHLVFAGPPGTGKTTIARVVAKIYCG
MUL_1204|M.ulcerans_Agy99           SRLKSSVAMELVRKQRGLAVAQRTHHLIFAGPPGTGKTTIARVVAKIYCG
MAB_2234c|M.abscessus_ATCC_199      ARLKSSVAMALRRQDRGLAVGHRTHHLVFAGPPGTGKTTIARVVAKIYCG
                                       :::. *   *  :*: *.: ::*::*:***************:: .*

TH_3592|M.thermoresistible__bu      LGVISEPKLVETSRKDFVAEYEGQSAVKTARTIDRALGGVLFIDEAYTLV
MSMEG_0059|M.smegmatis_MC2_155      LGVIAEPKLIETSRKDFVAEYEGQSAVKTSKTIDRALGGVLFIDEAYTLV
Mflv_0773|M.gilvum_PYR-GCK          LGVIGEPKLIETSRKDFVAEYEGQSAVKTARTIDRAMDGVLFIDEAYTLV
Mvan_0072|M.vanbaalenii_PYR-1       LGVIAEPKLVETSRKDFVAEYEGQSAVKTARTIDRAMGGVLFIDEAYTLV
Mb3898|M.bovis_AF2122/97            LGVIAEPKLVETSRKDFVAEYEGQSAVKTAKTIDQALGGVLFIDEAYALV
Rv3868|M.tuberculosis_H37Rv         LGVIAEPKLVETSRKDFVAEYEGQSAVKTAKTIDQALGGVLFIDEAYALV
MLBr_00055|M.leprae_Br4923          LGVISEPKLVETSRKDFVAEYEGQSAVKAAKTIDLALGGVLFIDEAYALV
MMAR_5443|M.marinum_M               LGVIAEPKLVETSRKDFVAEYEGQSAAKTAKTIDQALGGVLFIDEAYALV
MAV_4871|M.avium_104                LGLLKRENIREVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALV
MUL_1204|M.ulcerans_Agy99           LGLLKRENIREVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALV
MAB_2234c|M.abscessus_ATCC_199      LGLLKRENVREVHRADLIGQHIGETEAKTNAVIDSALDGVLFLDEAYALV
                                    **:: . :: *. * *::.:: *:: .*:   ** *:.****:****:**

TH_3592|M.thermoresistible__bu      QERDGRADPFGTEALDTLLARMENDRDRLVVIIAGYSADIDRLLEANDGL
MSMEG_0059|M.smegmatis_MC2_155      QERNGQTDPFGAEALDTLLARMENDRDRLVVIIAGYSNDIDRLLEVNDGL
Mflv_0773|M.gilvum_PYR-GCK          QERDGRADPFGTEALDTLLARMENDRDRLVVIIAGYSNDIDRLLESNDGL
Mvan_0072|M.vanbaalenii_PYR-1       QERDGRADPFGTEALDTLLARMENDRDRLVVIIAGYSNDIDRLLETNDGL
Mb3898|M.bovis_AF2122/97            QERDGRTDPFGQEALDTLLARMENDRDRLVVIIAGYSSDIDRLLETNEGL
Rv3868|M.tuberculosis_H37Rv         QERDGRTDPFGQEALDTLLARMENDRDRLVVIIAGYSSDIDRLLETNEGL
MLBr_00055|M.leprae_Br4923          QERDGRTDPFGQEALDTLLARMENDRDRLVVIIAGYSSDIDRLLETNEGL
MMAR_5443|M.marinum_M               QERDGRTDPFGQEAMDTLLARMENDRDRLVVIIAGYSSDIDRLLETNEGL
MAV_4871|M.avium_104                AT--GAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDKFLDTNEGL
MUL_1204|M.ulcerans_Agy99           AT--GAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDKFLDTNEGL
MAB_2234c|M.abscessus_ATCC_199      ST--GAKNDFGLVAIDTLLARMENDRDRLVVIVAGYRAELDQFLDTNEGL
                                        *  : **  *:*****************:***  ::*::*: *:**

TH_3592|M.thermoresistible__bu      RSRFATRIEFDSYSPDEIVEIATVLAAGNDSSLSDEAAKRVLDAATLLSQ
MSMEG_0059|M.smegmatis_MC2_155      RSRFATRIEFDSYSPDEIVEISKVIATANDSRLDDTAAKRVLEAATTLSQ
Mflv_0773|M.gilvum_PYR-GCK          RSRFATRIEFEPYAPQEIVDIAKVIAAGNDSSLSEDAAKHVLEAATLLTQ
Mvan_0072|M.vanbaalenii_PYR-1       RSRFSTRIEFDSYSPEEIVDIARVIAAHNDSSLTDEAAKRVLEAATLLSQ
Mb3898|M.bovis_AF2122/97            RSRFATRIEFDTYSPEELLEIANVIAAADDSALTAEAAENFLQAAKQLEQ
Rv3868|M.tuberculosis_H37Rv         RSRFATRIEFDTYSPEELLEIANVIAAADDSALTAEAAENFLQAAKQLEQ
MLBr_00055|M.leprae_Br4923          RSRFATRIEFDTYSPDELLEIAKVIATDADSSLSAEASKNLLEAAKQLAQ
MMAR_5443|M.marinum_M               RSRFATRIEFDTYSPEELLEIAKVIAAGNDSTLSTAAADELLQAAKTLHE
MAV_4871|M.avium_104                RSRFTRNIDFPSYAPSELVEIATKMAEQRDSVFEQAALDHMEELFTKLAR
MUL_1204|M.ulcerans_Agy99           RSRFTRSIDFPSYTSHELVEIAHKMAEQRDSIFEPAALQDLEGLFARLAA
MAB_2234c|M.abscessus_ATCC_199      RSRFTRSINFPSYAPSELVEIAAAMASVRDSKFDEGAEAELLTAFSAMCA
                                    ****:  *:* .*:. *:::*:  :*   ** :   *   .      :  

TH_3592|M.thermoresistible__bu      RTLN-----GKPALDIAGNGRYARQLVEAGEQNRDMRLSRL--PDIESLG
MSMEG_0059|M.smegmatis_MC2_155      RSLN-----GKPALDIAGNGRYARQLVEAGEQNRDMRLARS--LDFDSLG
Mflv_0773|M.gilvum_PYR-GCK          STSN-----GKPALDVAGNGRYARQLVEAGEQNRDMRLSRS--LDFDNLD
Mvan_0072|M.vanbaalenii_PYR-1       STSN-----GKPALDVAGNGRYARQLVEAGEQTRDMRLARS--PDFDTLD
Mb3898|M.bovis_AF2122/97            RMLR-----GRRALDVAGNGRYARQLVEASEQCRDMRLAQV--LDIDTLD
Rv3868|M.tuberculosis_H37Rv         RMLR-----GRRALDVAGNGRYARQLVEASEQCRDMRLAQV--LDIDTLD
MLBr_00055|M.leprae_Br4923          RTLR-----GRPALDVAGNGRYARQLVEAAEQCRDMRLARG--VDIEQLD
MMAR_5443|M.marinum_M               RTLR-----GRPALDIAGNGRYARQLVEASEQYRDMRLAQG--LDIEALD
MAV_4871|M.avium_104                ESTPDANGISRRNLDIAGNGRFVRNIVERAEEEREFRLDHSEHAGTGEFT
MUL_1204|M.ulcerans_Agy99           GSTPDSNGVSRRSLDIAGNGRFVRNIVERSEEEREFRLDHSEHAGSGEFS
MAB_2234c|M.abscessus_ATCC_199      AEAPDTRGIARRSIDVAGNGRFVRNVVERSEEEREHRLDN---SGAEEFS
                                             .:  :*:*****:.*::** .*: *: ** .    .   : 

TH_3592|M.thermoresistible__bu      VEQLSEISGDDMAAAIADVHARLNISE-------
MSMEG_0059|M.smegmatis_MC2_155      VDQLSEINGDDMAAAIASVHSRLNIGE-------
Mflv_0773|M.gilvum_PYR-GCK          VETLSEITGDDIAAAIASVHARLNISG-------
Mvan_0072|M.vanbaalenii_PYR-1       VEQLSEINGDDMAAAITSVHGRMDISG-------
Mb3898|M.bovis_AF2122/97            EDRLREINGSDMAEAIAAVHAHLNMRE-------
Rv3868|M.tuberculosis_H37Rv         EDRLREINGSDMAEAIAAVHAHLNMRE-------
MLBr_00055|M.leprae_Br4923          VDRLQEINGSDMAEAIATVHAHLNIRE-------
MMAR_5443|M.marinum_M               VDRLQEINGADMAEAIATVHAHLNMRE-------
MAV_4871|M.avium_104                DEELMTITDDDVARSVEPLLRGLGLSVPA-----
MUL_1204|M.ulcerans_Agy99           DDELMTITGSDVGRSVEPLLRGLGLSVPA-----
MAB_2234c|M.abscessus_ATCC_199      DDDLMTVTVEDVRASVEAIVAGLGLSASGASVKK
                                     : *  :.  *:  ::  :   :.: