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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3481 | - | - | 100% (600) | AMP-dependent synthetase and ligase |
M. thermoresistible (build 8) | TH_4043 | - | 2e-99 | 36.85% (597) | PUTATIVE AMP-dependent synthetase and ligase |
M. thermoresistible (build 8) | TH_2878 | - | 3e-36 | 27.78% (522) | PUTATIVE AMP-binding enzyme, putative |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2210 | fadD15 | 0.0 | 71.74% (506) | long-chain-fatty-acid-CoA ligase fadD15 (fatty-acid-CoA |
M. gilvum PYR-GCK | Mflv_2962 | - | 0.0 | 71.52% (597) | AMP-dependent synthetase and ligase |
M. tuberculosis H37Rv | Rv2187 | fadD15 | 0.0 | 71.24% (598) | long-chain-fatty-acid-CoA ligase fadD15 (fatty-acid-CoA |
M. leprae Br4923 | MLBr_00887 | - | 0.0 | 67.84% (597) | putative long-chain-fatty-acid-CoA ligase |
M. abscessus ATCC 19977 | MAB_1978c | - | 0.0 | 68.61% (599) | long-chain-fatty-acid--CoA ligase FadD |
M. marinum M | MMAR_5275 | fadD15_1 | 0.0 | 71.19% (597) | long-chain-fatty-acid-CoA ligase FadD15_1 |
M. avium 104 | MAV_2307 | - | 0.0 | 69.73% (598) | putative acyl-CoA dehydrogenase |
M. smegmatis MC2 155 | MSMEG_4254 | - | 0.0 | 71.45% (599) | AMP-binding enzyme |
M. ulcerans Agy99 | MUL_3542 | fadD15 | 0.0 | 70.07% (598) | long-chain-fatty-acid-CoA ligase FadD15 |
M. vanbaalenii PYR-1 | Mvan_3549 | - | 0.0 | 74.12% (599) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_5275|M.marinum_M --MREWAVPADFTVTAEDNVASCVYTHERDDPDHVIFQRLVDGTWTDVTC Mvan_3549|M.vanbaalenii_PYR-1 --MREFSVPATFTVGENDNVVSTVYSHERDDPDHVIFQRLVNGTWVDVTC TH_3481|M.thermoresistible__bu --VREFHEPATFTVGERDNIVSAVFDHERDDPQHVIFRRRIDGRWTDVTC Mflv_2962|M.gilvum_PYR-GCK MTAREFTVPAPFTVEERDNIVGAVFTHERDDPDHVIFQRLVDGKWIDVTA MSMEG_4254|M.smegmatis_MC2_155 --MREDSIPASFTVGEYDNVAGCVYAHETDDPDHVILRRLVDGTWTDVTC Mb2210|M.bovis_AF2122/97 -------------------------------------------------- Rv2187|M.tuberculosis_H37Rv --MREISVPAPFTVGEHDNVAAMVFEHERDDPDYVIYQRLIDGVWTDVTC MLBr_00887|M.leprae_Br4923 --MREFSVPTRFSVGEHDNIAAVVFEHERDDPNLVIYQRQIDGVWTDVTC MAV_2307|M.avium_104 --MREYSVPARFSVGENENIATMVFEHERDDPNFVIYQRQVDGEWTDVTC MUL_3542|M.ulcerans_Agy99 --MRQYSVPARFSVDERDNVAAMVFEHERDDPDHIIYQRQIDGIWTDITC MAB_1978c|M.abscessus_ATCC_199 --MREFSVPAPFTVEDNASVVRAVYDYEREDPNQAAFSRLIDDTWTPVTY MMAR_5275|M.marinum_M AQAAQQIRAAALGLIAEGVNAGDRVAILSATRYEWVILDYAILSVGAVTV Mvan_3549|M.vanbaalenii_PYR-1 RQAAEQIRSVASGLIAEGVQPGDRVALLSATRYEWPILDYAILSVGAVTV TH_3481|M.thermoresistible__bu AQAAEQVRAAALGLIAEGVQPGDRVALMSATRYEWVILDYAILAVGALTV Mflv_2962|M.gilvum_PYR-GCK RQAAGQIRSAARGLIAEGVQAGDRVALLSATRYEWPILDFAILSIGAVTV MSMEG_4254|M.smegmatis_MC2_155 AQAAAQIRSAALGLIAEGVQPGDRVAILSATRYEWPIIDFAILSIGAVTV Mb2210|M.bovis_AF2122/97 --------------------------------------------MGAVTV Rv2187|M.tuberculosis_H37Rv AEAANQIRAAALGLISLGVQAGDRVVIFSATRYEWAILDFAILAVGAVTV MLBr_00887|M.leprae_Br4923 AEAASQIRSAALGLIALGMQAGDRVSIFSATCFEWAILDLAILSVGAVTV MAV_2307|M.avium_104 AEAAAQIRSAALGLISLGVQAGDRVSIFSATRYEWAILDLAILAVGAVTV MUL_3542|M.ulcerans_Agy99 AEAARHIRSAALGLIALGVQASDRVSIFSATCYEWAILDLAILAVGAVTV MAB_1978c|M.abscessus_ATCC_199 AEAAAQIRAVANGLIAKGVAPGDRVALISATRYEWTIIDYAVLSIGAITV :**:** MMAR_5275|M.marinum_M PIYDTSSAEQVRWVLEDSGAVLAVAETDAHAQLIKQLSDELPSLRKILHL Mvan_3549|M.vanbaalenii_PYR-1 PIYETSSPEQVRWVLEDSGAVLAFVELEAHALMVKELLNELPALRKVMVI TH_3481|M.thermoresistible__bu PIFETSSADQVRWVLQDSGAVLAVVETEKHGQLVKSVQDDAPALRKTLLI Mflv_2962|M.gilvum_PYR-GCK PIYETSSAEQVQFVLADSGAVAAIAETDAHAAHIEAQRDTLPALRRIYVI MSMEG_4254|M.smegmatis_MC2_155 PIYETSAAEQVRFVLENSESVLVFAETDAHADKVEQLRDQLPALRKVFRI Mb2210|M.bovis_AF2122/97 PIYETSSAEQVRWVLQDSEAVVLFAETDSHATMVAELSGSVPALREVLQI Rv2187|M.tuberculosis_H37Rv PTYETSSAEQVRWVLQDSEAVVLFAETDSHATMVAELSGSVPALREVLQI MLBr_00887|M.leprae_Br4923 PIYETSSAKQVRWILQDSDAVLVFAETDAHATMVNQLAGELPALRQVLQI MAV_2307|M.avium_104 PIYETSSAEQVRWVLQDSEAVLAFAETDEHAAMVTELTAELPALRRVLHI MUL_3542|M.ulcerans_Agy99 PIYETSSAEQVRWVLQNSEAVLAFAETDAHAAMIAELTGDLPALRRVLVI MAB_1978c|M.abscessus_ATCC_199 PIYETSSADQVRWVLQDSAAVALFVESDAHAKIAEELAPELPNLRTVFHI * ::**:..**:::* :* :* ..* : *. * ** : MMAR_5275|M.marinum_M D-SDGPAALDELAEAGKSVARDQLDDRLAALRSSDPATLIYTSGTTGRPK Mvan_3549|M.vanbaalenii_PYR-1 E-TAAPSALDALAEAGATVDPGEVDRRVAAIRSADPATLIYTSGTTGRPK TH_3481|M.thermoresistible__bu E-GSGPTAIDELTAAGSGVDRAELDNRLAGIRAADPATLIYTSGTTGRPK Mflv_2962|M.gilvum_PYR-GCK D-GS-VPALDELAEAGASVDAAAVDERVASIRSTDAATLIYTSGTTGRPK MSMEG_4254|M.smegmatis_MC2_155 D-GSGTPALDELAEAGKDVDPAELDKRLANIKSSDPATLIYTSGTTGQPK Mb2210|M.bovis_AF2122/97 A-GSGPNALDRLTEAGASVDPAELTARLAALRSTDPATLIYTSGTTGRPK Rv2187|M.tuberculosis_H37Rv A-GSGPNALDRLTEAGASVDPAELTARLAALRSTDPATLIYTSGTTGRPK MLBr_00887|M.leprae_Br4923 N-SAGATALDQLAEAGASVDVAQLANRLKTLRAQDPATLIYTSGTTGRPK MAV_2307|M.avium_104 D-GSGPKALDQLAEAAAGVEPAELTARLDGLRAQDPATLIYTSGTTGRPK MUL_3542|M.ulcerans_Agy99 N-GSGPKALEQLAEEGGSVDRAELTARLDALRSSDRATLIYTSGTTGRPK MAB_1978c|M.abscessus_ATCC_199 ASTSAPAALDELAEAGAGVDPAELEGRLAAIKATDPATLIYTSGTTGRPK *:: *: . * : *: ::: * ***********:** MMAR_5275|M.marinum_M GCQLTHSNLLYEARGAASCFPTLLRKGERLLVFLPLAHVLARSLSMSAFA Mvan_3549|M.vanbaalenii_PYR-1 GCQLTHSNLLYETRGATACFPGLLRKGERLLVFLPLAHVLARALSMTAFA TH_3481|M.thermoresistible__bu GCVLTHSNLVHEVRADRDCFPTLLDKGQRMLTFLPLAHVLARAISMAAFH Mflv_2962|M.gilvum_PYR-GCK GCQLTHSNLLYEIRGAKACFPEHLAKGEKLLVFLPLAHVLARALTIGAFS MSMEG_4254|M.smegmatis_MC2_155 GCQLTHSNLLHEIRGQKECFPDHLAKGERILVFLPLAHVLARAITIGAFA Mb2210|M.bovis_AF2122/97 GCQLTQSNLVHEIKGARAYHPTLLRKGERLLVFLPLAHVLARAISMAAFH Rv2187|M.tuberculosis_H37Rv GCQLTQSNLVHEIKGARAYHPTLLRKGERLLVFLPLAHVLARAISMAAFH MLBr_00887|M.leprae_Br4923 GCQLTHSNLLYEVRGAKECLPTLLQPGQRLLVFLPLAHVLARALTLSAFT MAV_2307|M.avium_104 GCQLTHSNLLYETRGAKESLPTLLDQGQRLLIFLPLAHVLARSLTLSAFA MUL_3542|M.ulcerans_Agy99 GCQLTHSNLLHEIRGTQECLPTLLTPGQRLLVFLPLAHVLARALTLSAFA MAB_1978c|M.abscessus_ATCC_199 GCQLTHSNLVYETRGARAVFPDYLQKGSRTLIFLPLAHVLARGIAMACFQ ** **:***::* :. * * *.: * **********.::: .* MMAR_5275|M.marinum_M NKVTIGYTGDIKNLVATLGVFKPTVVVSVPRVFEKVYNTAELKARDSGRG Mvan_3549|M.vanbaalenii_PYR-1 NGVTIGYTSDIKNLVPMFGQFKPTVIVSVPRVFEKVYNTAELNAQDSGKG TH_3481|M.thermoresistible__bu SKVTQGFTSDLANLVPLFGEFKPTAVVSVPRVFEKVYNTAELNAQEGGKG Mflv_2962|M.gilvum_PYR-GCK NGVTLGFTSDIKNLVPMFAVFQPTLVVSVPRVFEKVYNTAELNAETGGKG MSMEG_4254|M.smegmatis_MC2_155 NKVTLGFTSDIKNLVPMFGVFKPTLVISVPRVFEKVYNTAEQNARNDGKG Mb2210|M.bovis_AF2122/97 SKVTVGFTSDIKNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANAGKG Rv2187|M.tuberculosis_H37Rv SKVTVGFTSDIKNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANAGKG MLBr_00887|M.leprae_Br4923 YKMTVGFTSDIKNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANEGKS MAV_2307|M.avium_104 NKVTVGFTSDIKNLLPMFAVFKPTVVVSVPRVFEKVYNTAEQNAANDGKG MUL_3542|M.ulcerans_Agy99 SKVTVGFTSDIKNLLPLFAVFKPTVVVSVPRVFEKVYNTAEQNASNDGKG MAB_1978c|M.abscessus_ATCC_199 SKVSVGFTSDIKTLVPTFGIFKPTFIVSVPRIFEKVYNTARQNAQNDGKG :: *:*.*: .*:. :. *:** ::****:********. :* *:. MMAR_5275|M.marinum_M MIFDLAVATAIAWSKALDTGGAGLLLRARHALFDRLVYEKLRSALGGDCH Mvan_3549|M.vanbaalenii_PYR-1 AIFAMAVQTAIDWSMAQDTGGPGLLLRAKHALFDRLVYGKLRAATGGDCR TH_3481|M.thermoresistible__bu AIFAQAARTAIDWSKALDTGGPGLWLRAKHALFDKLVYGKLRAALGGECR Mflv_2962|M.gilvum_PYR-GCK KIFTAAANTAIEYSKALDSGGPGLVLKLKHALFDKLVYGKLRAALGGRCH MSMEG_4254|M.smegmatis_MC2_155 KIFEIAAETAIEFSKAQDKGGPGLLLRVKHAVFDKLVYGKLRAALGGECH Mb2210|M.bovis_AF2122/97 RIFAIAAQTAVDWSEACDRGGPGLLLRAKHAVFDRLVYRKLRAALGGNCR Rv2187|M.tuberculosis_H37Rv RIFAIAAQTAVDWSEACDRGGPGLLLRAKHAVFDRLVYRKLRAALGGNCR MLBr_00887|M.leprae_Br4923 RIFAMAAQTAVEWSEASHRGGPGLLLRARHAVFDRLVYRKLRAALGGDCH MAV_2307|M.avium_104 RIFAMAVQTAVDWSEAADRGRRGPLLRAKHALFDRLVYHKLRAALGGDCH MUL_3542|M.ulcerans_Agy99 AIFKLAAQTAVDWSRAWDDGRPGLLLRAKHALFDRLVYHKLRAALGGDCH MAB_1978c|M.abscessus_ATCC_199 KIFDAAADTAIEYSEALDKGGPGIVLRAKRAAFDKLVYGKLRAALGGECV ** *. **: :* * . * * *: ::* **:*** ***:* ** * MMAR_5275|M.marinum_M AAVSGGAPLGTRLCHFYRGIGLTIYEGYGLTETSAAITANRIGQERVGTV Mvan_3549|M.vanbaalenii_PYR-1 ASISGGAPLGARLGHFFRGVGLTIYEGYGMTETSAAITANRIGELKVGSV TH_3481|M.thermoresistible__bu AAISGGAPLGARLGHFFRGAGVTVYEGYGLTETSAAITVNRMDDLRIGTV Mflv_2962|M.gilvum_PYR-GCK AAISGGAPLGARLGHFYRGVGLSIYEGYGLTETSAAITVNRVGDLRVGSV MSMEG_4254|M.smegmatis_MC2_155 AAISGGAPLGERLGHFYRGVGLSIYEGYGLTETSAAITVNRLNDLKVGSV Mb2210|M.bovis_AF2122/97 AAVSGGAPLGARLGHFYRGAGLTIYEGYGLSETSGGVAISQFNDLKIGTV Rv2187|M.tuberculosis_H37Rv AAVSGGAPLGARLGHFYRGAGLTIYEGYGLSGTSGGVAISQFNDLKIGTV MLBr_00887|M.leprae_Br4923 ASVSGGAPLGARLGHFYRGVGLTIHEGYGLTETSAAITLNQAGNVKVGTV MAV_2307|M.avium_104 ASVSGGAPLGSRLGHFFRGVGLTIHEGYGLTETSSAITVNQVGNVKIGTV MUL_3542|M.ulcerans_Agy99 AAVSGGAPLGARLGHFYRGVGLTIYEGYGLTETSAAVTVNQIDALKIGTV MAB_1978c|M.abscessus_ATCC_199 ASISGGAPLGARLGHFYRGVGLTIYEGYGLTETTAACAVNVIGGLKIGSV *::******* ** **:** *::::****:: *:.. : . . ::*:* MMAR_5275|M.marinum_M GNLLPGNSMAIAEDGEVLVRGGVVFTGYWHNEKATAEAIV-DGWFHTGDL Mvan_3549|M.vanbaalenii_PYR-1 GKLLPGNSMAIANDGELLVRGGVVFNGYWRNEKATRETVV-NGWLHTGDL TH_3481|M.thermoresistible__bu GKLVPGCSMKLAPDGELLVKGGVVFNGYWQNEEATKEAIV-DGWFHTGDL Mflv_2962|M.gilvum_PYR-GCK GKLVPGNSMRLGEDGELLVRGGVVFNGYWGNEEETRAVFT-DGWFHTGDL MSMEG_4254|M.smegmatis_MC2_155 GRLVPGNSMRIADDGELLVKGGVVFNGYWKNEDETKAVIDADGWFHTGDL Mb2210|M.bovis_AF2122/97 GKPVPGNSLRIADDGELLVRGGVVFSGYWRNEQATTEAFT-DGWFKTGDL Rv2187|M.tuberculosis_H37Rv GKPVPGNSLRIADDGELLVRGGVVFSGYWRNEQATTEAFT-DGWFKTGDL MLBr_00887|M.leprae_Br4923 GNLLPGNSMRIADDGELLVRGNVVFSGYWHNEQGTIEAFT-EGWFKTGDL MAV_2307|M.avium_104 GTLLPGNSMRIAEDGELLVRGGVVFSGYWRNEQATADAFT-DGWFKTGDL MUL_3542|M.ulcerans_Agy99 GKLVPGNSLRIADDGELLVRGGVVFSGYWRNEQATDEAFT-DGWFRTGDL MAB_1978c|M.abscessus_ATCC_199 GRPLPGNAVKIAEDGELLVSGGVVFSGYWNNETATSESIV-DGWFHTGDL * :** :: :. ***:** *.***.*** ** * . :**::**** MMAR_5275|M.marinum_M GSVDDAGFLSIVGRKKEIIVTAGGKNVAPAVLEDQLRAHPLISQAMVVGD Mvan_3549|M.vanbaalenii_PYR-1 GSIDEDGYLSIVGRKKEIIVTAGGKNVAPAVLEDQLRAHPLISQAMAVGD TH_3481|M.thermoresistible__bu GSIDDDGFLTIVGRKKEIIVTAGGKNVAPAVLEDQLRAHPLISQAMAVGD Mflv_2962|M.gilvum_PYR-GCK GAIDDDGFLTIVGRKKEIIVTAGGKNVAPAQLEDRLRAHPLISQAMAVGD MSMEG_4254|M.smegmatis_MC2_155 GAIDDNGFLTIVGRKKEIIVTAGGKNVAPALLEDRLRAHPLISQAMAVGD Mb2210|M.bovis_AF2122/97 GAVDEDGFLTITGRKKEIIVTAGGKNVAPAVLEDQLRAHPLISQAVVVGD Rv2187|M.tuberculosis_H37Rv GAVDEDGFLTITGRKKEIIVTAGGKNVAPAVLEDQLRAHPLISQAVVVGD MLBr_00887|M.leprae_Br4923 GAIDEDGFLTITGRKKEIIVTAGGKNVAPALLEDQLRAHPLISQALVVGD MAV_2307|M.avium_104 GVLDDDGFLKIVGRKKELIVTAGGKNVAPAVLEDRLRAHPLISQAMVVGD MUL_3542|M.ulcerans_Agy99 GAIDDDGFLSITGRKKELIVTAGGKNVAPAVLEDQLRAHPLISQAVVVGD MAB_1978c|M.abscessus_ATCC_199 GAIDEDGFVTITGRKKEIIVTAGGKNVAPAVLEDQLRAHPLISQAMAVGD * :*: *::.*.*****:************ ***:**********:.*** MMAR_5275|M.marinum_M NRPFVGALIAIDPEGFEVWKQHHSKAAGASVADLIDDPDLTAEIDQAVKQ Mvan_3549|M.vanbaalenii_PYR-1 AKPFIGALIAIDTEAFEVWKQHHGKAPAASVAELIDDPDLVGEIDLAVKS TH_3481|M.thermoresistible__bu QKPFIGALITIDPEAFETWKQHRGKNPDATLAEMTEDPDLVAEIDEAIQQ Mflv_2962|M.gilvum_PYR-GCK QQPFIAALITVDTEAFPGWKERHHKASDASVADLADDPDLLAEIELAVKD MSMEG_4254|M.smegmatis_MC2_155 KQPFIAALITIDPEAFPAWKERNAKSASATVAELAEDPDLIAEINLAVKE Mb2210|M.bovis_AF2122/97 AKPFIGALITIDPEAFEGWKQRNSKTAGASVGDLATDPDLIAEIDAAVKQ Rv2187|M.tuberculosis_H37Rv AKPFIGALITIDPEAFEGWKQRNSKTAGASVGDLATDPDLIAEIDAAVKQ MLBr_00887|M.leprae_Br4923 AKPFVGALITIDPEAFNGWKQRNSKAADAAIGDLTTDPDLVAEVDAAVKQ MAV_2307|M.avium_104 NKPFIGALITIDPEAFGGWKQRNHKGAGASVADLTTDPDLVAEVDAAIKD MUL_3542|M.ulcerans_Agy99 AKPFIGALITIDPEAFGGWKQRNSKADHAAVRDLAEDPDLVAGVDAAVKE MAB_1978c|M.abscessus_ATCC_199 KQPFIGALITIDPEAIDGWKQRNGKPADATVADLVEDSDLLAEIGTAVKA :**:.***::*.*.: **::. * *:: :: *.** . : *:: MMAR_5275|M.marinum_M ANQVVSQAESIRKFCILPVDFTVLTGELTPTLKVKRNVVAERFASEIDSL Mvan_3549|M.vanbaalenii_PYR-1 ANQAVSKAEAIRKFRILPVDFTVFTGELTPTLKVRRNVVADKFAEEIERL TH_3481|M.thermoresistible__bu ANKAVSRAEAIRKFRILPVDFTVEDGELTPTLKLKRAVVAEKYAAEIEKI Mflv_2962|M.gilvum_PYR-GCK ANQAVSKAEAIRKFRILPVDFTEDTGELTPTLKVKRKVVAEKFAADIEAL MSMEG_4254|M.smegmatis_MC2_155 ANQAVSNAEAIRKFRILPVDFTEDTGELTPTLKVKRKVVAEKFATDIAAL Mb2210|M.bovis_AF2122/97 ANLAVSHAESIRKFRILPVDFTEDTGELTPTMKVKRKVVAEKFASDIEAI Rv2187|M.tuberculosis_H37Rv ANLAVSHAESIRKFRILPVDFTEDTGELTPTMKVKRKVVAEKFASDIEAI MLBr_00887|M.leprae_Br4923 ANLSVSHAESIRKFRILPVDFTEQTGELTPTMKVKRNVVAQKFASDIEAI MAV_2307|M.avium_104 ANQAVSHAESIRKFRILPVDFTEDTGELTPTMKVKRNVVAEKFASDIEAI MUL_3542|M.ulcerans_Agy99 ANLAVSHAESIRKFRILHVDFTEDTGELTPTMKVKRNVVAEKFSVEIEAI MAB_1978c|M.abscessus_ATCC_199 ANQVVSHAEAIKKFRILPVDFTEATGEMTPTLKVKRNVVAEKFASDIDAI ** **.**:*:** ** **** **:***:*::* ***:::: :* : MMAR_5275|M.marinum_M YRKQ-- Mvan_3549|M.vanbaalenii_PYR-1 YTTDSA TH_3481|M.thermoresistible__bu YSS--- Mflv_2962|M.gilvum_PYR-GCK YAKG-- MSMEG_4254|M.smegmatis_MC2_155 YA---- Mb2210|M.bovis_AF2122/97 YNKE-- Rv2187|M.tuberculosis_H37Rv YNKE-- MLBr_00887|M.leprae_Br4923 YEKD-- MAV_2307|M.avium_104 YAKD-- MUL_3542|M.ulcerans_Agy99 YTKD-- MAB_1978c|M.abscessus_ATCC_199 YAGAPQ *