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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2973 | - | - | 100% (273) | putative peptidase S1 and S6, chymotrypsin/Hap |
| M. thermoresistible (build 8) | TH_4473 | - | 2e-42 | 37.07% (294) | PUTATIVE peptidase S1 and S6, chymotrypsin/Hap |
| M. thermoresistible (build 8) | TH_4008 | - | 5e-35 | 34.21% (266) | PUTATIVE Trypsin |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1009 | - | 3e-38 | 35.64% (289) | serine protease |
| M. gilvum PYR-GCK | Mflv_1889 | - | 4e-40 | 35.84% (293) | peptidase S1 and S6, chymotrypsin/Hap |
| M. tuberculosis H37Rv | Rv1223 | htrA | 1e-38 | 36.33% (278) | serine protease HtrA |
| M. leprae Br4923 | MLBr_01078 | htrA | 2e-38 | 36.07% (280) | possinble serine protease |
| M. abscessus ATCC 19977 | MAB_1078 | - | 9e-39 | 35.89% (287) | putative serine protease |
| M. marinum M | MMAR_4214 | htrA | 2e-39 | 36.33% (278) | serine protease HtrA (DegP protein) |
| M. avium 104 | MAV_1366 | - | 7e-39 | 36.33% (278) | trypsin |
| M. smegmatis MC2 155 | MSMEG_5486 | - | 1e-42 | 37.37% (289) | peptidase S1 and S6, chymotrypsin/Hap |
| M. ulcerans Agy99 | MUL_4517 | htrA | 1e-39 | 36.33% (278) | serine protease HtrA (DegP protein) |
| M. vanbaalenii PYR-1 | Mvan_4842 | - | 1e-39 | 35.74% (291) | peptidase S1 and S6, chymotrypsin/Hap |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4214|M.marinum_M -----------------------------MTSDQGNNSGQDGGPRLAPRP
MUL_4517|M.ulcerans_Agy99 -----------------------------MTSDQGNNSGQDGGPRLAPRP
Rv1223|M.tuberculosis_H37Rv MDTRVDTDNAMP-----ARFSAQIQNEDEVTSDQGNNGGPNGGGRLAPRP
MLBr_01078|M.leprae_Br4923 MNTRVDTDNAVIRYRRRNRPCLERSEEDNVTSDQGTNNDQNPGHHLATRP
MAV_1366|M.avium_104 -----------------------------MTSDPGYDQAKDSANRLAPRP
Mflv_1889|M.gilvum_PYR-GCK ------------------------MKMVEAGATGAEPDCCRKGNRTLRPF
Mvan_4842|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5486|M.smegmatis_MC2_155 --------------------------------------------------
Mb1009|M.bovis_AF2122/97 --------------------------------------------------
MAB_1078|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2973|M.thermoresistible__bu --------------------------------------------------
MMAR_4214|M.marinum_M ISRPPVDSAARQTFGRPSGVQGSFVAERVRPQRYRDQSEYEPHDQPADPV
MUL_4517|M.ulcerans_Agy99 ISRPPVDSAARQTFGRPSGVQGSFVAERVRPQRYRDQSEYEPHDQPADPV
Rv1223|M.tuberculosis_H37Rv VFRPPVDPASRQAFGRPSGVQGSFVAERVRPQKYQDQSDFTPNDQLADPV
MLBr_01078|M.leprae_Br4923 VARPPVDAASREAFGRPCGFSGSFVAEYVRPQKYRDRSEFRPDDQPADPV
MAV_1366|M.avium_104 ISRPPVDPASRREFGRPAGLRGSFVAERVRPKKYREQSEFRPSEQSADPV
Mflv_1889|M.gilvum_PYR-GCK SVRLGTLSWQRSLFTRQDQFEGEHCSDMTNHPRYS--PTPQPGRQSGYTG
Mvan_4842|M.vanbaalenii_PYR-1 ---------------------------MTNQPSYS--PTPQPGRQSGYPG
MSMEG_5486|M.smegmatis_MC2_155 ---------------------------MTNHPRYSQQPDPRTGATPGYPG
Mb1009|M.bovis_AF2122/97 ---------MAKLARVVGLVQEEQPSDMTNHPRYS--PPPQQPGTPGYAQ
MAB_1078|M.abscessus_ATCC_1997 ---------------------------MTNDPHGS-----WAYRPSG---
TH_2973|M.thermoresistible__bu --------------------------------------------------
MMAR_4214|M.marinum_M LEEAFSRPVGGADSLQRHPIDAGALDAEKDGGQADEAD--DPWRDPGAAA
MUL_4517|M.ulcerans_Agy99 LEEAFSRPVGGADSLQRHPIDAGALDAEKDGGQADEAD--DPWRDPGAAA
Rv1223|M.tuberculosis_H37Rv LQEAFGRPFAGAESLQRHPIDAGALAAEKDGAGPDEPD--DPWRDPAAAA
MLBr_01078|M.leprae_Br4923 LAEAFSRPFGSVDSLQRHPIDAGALAAEKDATQLDEPD--DPWRDPAAAA
MAV_1366|M.avium_104 LQEAFSRPDGSPETLQRHPVDSGALAAEKDGVEPDHAD--DPWRDPGAPA
Mflv_1889|M.gilvum_PYR-GCK QVPPGSAGPAGSGSYEQQGTGSWDWRYATEQQRQAFRGPYDSPYDPYRGA
Mvan_4842|M.vanbaalenii_PYR-1 QVPPGHAGPR-TGSYEQQGSGGWDWRYATEQQRQAFR----APYDPYAGA
MSMEG_5486|M.smegmatis_MC2_155 GRP---------DPYQQ--TSQYDWRYAQQVQQ--------APQSPQTHQ
Mb1009|M.bovis_AF2122/97 GQQ---------QTYSQ----QFDWRYPPSPPPQ-------PTQYRQPYE
MAB_1078|M.abscessus_ATCC_1997 -------------SYSG----QHGHHQAPNHHAQS------SHHYQGQSY
TH_2973|M.thermoresistible__bu --------------------------------------------------
MMAR_4214|M.marinum_M ALGTPAVAAPLPQGALGRTGKLGVRDVLFGGQVSYLALIVLAVIALVIGA
MUL_4517|M.ulcerans_Agy99 ALGTPAVAAPLPQGALGRTGKLGVRDVLFGGQVSYLALIVLAVIALVIGA
Rv1223|M.tuberculosis_H37Rv ALGTPALAAPAPHGALAGSGKLGVRDVLFGGKVSYLALGILVAIALVIGG
MLBr_01078|M.leprae_Br4923 TLASPAVASPVPHTELGQCGKLGVRDVLFGGRVSYLALVILVFIALALGA
MAV_1366|M.avium_104 ALGTPAVAPSPSRSALGYGGKLGVRDVLFGGKVSYLALLVLLLIALVIGL
Mflv_1889|M.gilvum_PYR-GCK PMPGGPGQFPPPGMP--RQPQPQPRKRS-GSALAAGAIALALVSGGIGGG
Mvan_4842|M.vanbaalenii_PYR-1 PMPSGPGHHPRPGMP--VTPPRQPRKGSRATALAAGAVAVALVSGGIGGG
MSMEG_5486|M.smegmatis_MC2_155 TQPGFRPAYDPYRAPSTAQPVAIPAKKRSRAGLAAGALAVAVVSAGIGGG
Mb1009|M.bovis_AF2122/97 ALGGTRPGLIPGVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGA
MAB_1078|M.abscessus_ATCC_1997 GYPSQQPQQRPAQQP---QRQAQPKGRS-SGGLVVGAVVLALVSGGLGGT
TH_2973|M.thermoresistible__bu --------------------------------------------------
MMAR_4214|M.marinum_M LGGVIGRKTAEVVEAFTTSKVTLSTNG--------NAQEPAGRFTKVAAA
MUL_4517|M.ulcerans_Agy99 LGGVIGRKTAEVVEAFTTSKVTLSTNG--------NAQEPAGLFTKVAAA
Rv1223|M.tuberculosis_H37Rv IGGVIGRKTAEVVDAFTTSKVTLSTTG--------NAQEPAGRFTKVAAA
MLBr_01078|M.leprae_Br4923 IGGVIGRKTAEIVDAFTTSKVTLATTN--------NTEEPAGRFAKVAAA
MAV_1366|M.avium_104 IGGVVGRKTAEVAEAFTTSKVTLSTNG--------NGEAPAGRFAKVAAA
Mflv_1889|M.gilvum_PYR-GCK VAMLAHP--DHSLGGIS----ASGAAP-----SMPAASVPGGSVEAVAAK
Mvan_4842|M.vanbaalenii_PYR-1 VAMLVHP--DHGVPGIS----ASGAAP-----GMPAASVPAGSVEAVAAA
MSMEG_5486|M.smegmatis_MC2_155 VATLVHN--ESPQLGSP----AIGAAP-----TVPAAALPAGSVEQVAAK
Mb1009|M.bovis_AF2122/97 AASLVGF--NRAPAGPSGGPVAASAAP-----SIPAANMPPGSVEQVAAK
MAB_1078|M.abscessus_ATCC_1997 VGAVVADRQHKAPVVTSSSTGLTPIAPGRPPAAQPVASLPAGSVEQVAAK
TH_2973|M.thermoresistible__bu --------------------------------------------------
MMAR_4214|M.marinum_M VADSVVTIETKSDQEGMQGSGVIVDGRGYIVTNNHVISEAAN------NP
MUL_4517|M.ulcerans_Agy99 VADSVVTIETKSDQEGMQGSGVIVDGRGYIVTNNHVISEAAN------NP
Rv1223|M.tuberculosis_H37Rv VADSVVTIESVSDQEGMQGSGVIVDGRGYIVTNNHVISEAAN------NP
MLBr_01078|M.leprae_Br4923 VADSVVTIESKSDQEEMQGSGVIIDGRGYIVTNNHVISEAAN------KP
MAV_1366|M.avium_104 TAGAVVTIESKSDQEGMQGSGVVIDGRGYIVTNNHVISEAAN------NP
Mflv_1889|M.gilvum_PYR-GCK VVPSVVKLEVNQGRSTEEGSGVILSSDGLILTNNHVVAAAADNGAPGAPP
Mvan_4842|M.vanbaalenii_PYR-1 VVPSVVKLEVSQGRASEEGSGVILSTDGLILTNNHVVATAAG--AAGEPG
MSMEG_5486|M.smegmatis_MC2_155 VVPSVVKLETDLGRASEEGSGIILTADGLILTNNHVVAAAKG----DGPG
Mb1009|M.bovis_AF2122/97 VVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAK---PPLGS
MAB_1078|M.abscessus_ATCC_1997 VLPSVVKLETIMGRSSEEGSGVILSADGLVLTNAHVVQAAGD--------
TH_2973|M.thermoresistible__bu -----------------VGSGVVYRPN-IIITNAHVVGRARE--------
***:: ::** **: *
MMAR_4214|M.marinum_M SQFKTTVVFNDGKEVPASLVGRDPKTDLAVLKVDNVDNLTVARLGNSDKV
MUL_4517|M.ulcerans_Agy99 SQFKTTVVFNDGKEVPASLVGRDPKTDLAVLKVDNVDNLTVARLGNSDKV
Rv1223|M.tuberculosis_H37Rv SQFKTTVVFNDGKEVPANLVGRDPKTDLAVLKVDNVDNLTVARLGDSSKV
MLBr_01078|M.leprae_Br4923 SQFKTTVVFNDGKDVPANLVGRDPKTDLAVLKVDNVDNLTVARLGDSGKV
MAV_1366|M.avium_104 SQFKTTVVFNDGKEVPANLVGRDPKTDLAVLKVDNVDNLSVARLGDSDKV
Mflv_1889|M.gilvum_PYR-GCK GAAQTKVTFADGKSSTFEVIGTDPGSDIAVVRAKNVTDLTPIAVGSSADL
Mvan_4842|M.vanbaalenii_PYR-1 GPAKTKVTFADGKTAPFTVIGADPSSDIAVVRAQNVSGLTPITVGSSADL
MSMEG_5486|M.smegmatis_MC2_155 PAAQTKVTFADGTTRPFTVVGTDPSSDIAVVRAQDVSGLTPITLGSSANL
Mb1009|M.bovis_AF2122/97 PPPKTTVTFSDGRTAPFTVVGADPTSDIAVVRVQGVSGLTPISLGSSSDL
MAB_1078|M.abscessus_ATCC_1997 PGAKTTATIAGGKTSPFTVVGIDPGTDIAVVRITGASGLTPIALGSSANL
TH_2973|M.thermoresistible__bu ----VVLTFADREEAAGEVLATDTITDLAVVRSQ--RGNLPVPEFRTELP
. .: . . ::. *. :*:**:: . :
MMAR_4214|M.marinum_M RVGDEVLAVGAPLGLRSTVTEGIVSALHRPVPLSGEGSDTDTVIDAIQTD
MUL_4517|M.ulcerans_Agy99 RVGDEVLAVGAPLGLRSTVTEGIVSALHRPVPLSGEGSDTDTVIDAIQTD
Rv1223|M.tuberculosis_H37Rv RVGDEVLAVGAPLGLRSTVTQGIVSALHRPVPLSGEGSDTDTVIDAIQTD
MLBr_01078|M.leprae_Br4923 RVGDEVIAAGAPLGLRSTVTHGIVSALHRPVPLSGEGSDTDTVIDAIQTD
MAV_1366|M.avium_104 RVGDEVLAAGAPLGLRSTVTHGIVSALHRPVPLSGEGSDTDTVIDAVQTD
Mflv_1889|M.gilvum_PYR-GCK RVGQDVVAIGSPLGLEGTVTTGIISALNRPVAASGDARNQNTVLDAIQTD
Mvan_4842|M.vanbaalenii_PYR-1 RVGQDVVAIGSPLGLEGTVTTGIISALNRPVAAGGDARNQNTVLDAIQTD
MSMEG_5486|M.smegmatis_MC2_155 RVGQDVVAIGSPLGLEGTVTTGIVSALNRPVAAGGDTRNQNTVLDAIQTD
Mb1009|M.bovis_AF2122/97 RVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTD
MAB_1078|M.abscessus_ATCC_1997 VVGQSVVAIGSPLGLDGTVTTGIVSSLNRPVFTAGQAGNQDTVLDAIQTD
TH_2973|M.thermoresistible__bu RPGEWAVAIGSPLGFENTVTAGVISGLNRAIPGSGTS--TQSLIDLIQTD
*: .:* *:***: .*** *::*.*:*.: * ::::* :***
MMAR_4214|M.marinum_M ASINHGNSGGPLIDMDSQVIGINTAGKSLS--------DSASGLGFAIPV
MUL_4517|M.ulcerans_Agy99 ASINHGNSGGPLIDMDSQVIGINTAGKSLS--------DSASGLGFAIPV
Rv1223|M.tuberculosis_H37Rv ASINHGNSGGPLIDMDAQVIGINTAGKSLS--------DSASGLGFAIPV
MLBr_01078|M.leprae_Br4923 ASINHGNSGGPLIDMDSQVIGINTAGKSLS--------DSASGLSFAIPV
MAV_1366|M.avium_104 ASINHGNSGGPLIDMDSQVIGIDTAGKSLS--------DSASGLGFAIPI
Mflv_1889|M.gilvum_PYR-GCK AAINPGNSGGALVNMNGELVGINSAIATMGADA-GGPQGGSIGLGFAIPV
Mvan_4842|M.vanbaalenii_PYR-1 AAINPGNSGGALVNMNGELVGINSAIATMGADA-GAQQGGSIGLGFAIPV
MSMEG_5486|M.smegmatis_MC2_155 AAINPGNSGGALVNMNGELVGINSAIATMGGDS-PNAQSGSIGLGFAIPV
Mb1009|M.bovis_AF2122/97 AAINPGNSGGALVNMNAQLVGVNSAIATLGADS-ADAQSGSIGLGFAIPV
MAB_1078|M.abscessus_ATCC_1997 AAINPGNSGGALVNLNGELVGINSAIATMGGDSSGETQGGSIGLGFAIPV
TH_2973|M.thermoresistible__bu APISPGNSGGALLDVDGRVVGINEAYIPP--------ELGAVSLGFAIPA
*.*. *****.*::::..::*:: * . .: .*.****
MMAR_4214|M.marinum_M NEMKFVAETLIKDGKIVHPTIGITTR--------SVSNAIASGAQVANVK
MUL_4517|M.ulcerans_Agy99 NEMEFVAETLIKDGKIVHPTIGITTR--------SVSNAIASGAQVANVK
Rv1223|M.tuberculosis_H37Rv NEMKLVANSLIKDGKIVHPTLGISTR--------SVSNAIASGAQVANVK
MLBr_01078|M.leprae_Br4923 DEMKSVVQTLIKDGKIVHPTLGVSTR--------SVSNAIASGAQVANVK
MAV_1366|M.avium_104 NEAKEVAQTLIRDGKIVHPTLGVSTR--------SVSNAIASGAQVANVK
Mflv_1889|M.gilvum_PYR-GCK DQAKRIADEIIQTGSASRASLGVQVG----------NEAGVDGAKIVEVT
Mvan_4842|M.vanbaalenii_PYR-1 DQAKRIADEIIQTGSASRASLGVQVG----------NEAGVDGAKIVEVT
MSMEG_5486|M.smegmatis_MC2_155 DQAKRIADELIQNGVASHASLGVQVA----------NDRSSDGAKIVEVN
Mb1009|M.bovis_AF2122/97 DQAKRIADELISTGKASHASLGVQVT----------NDKDTPGAKIVEVV
MAB_1078|M.abscessus_ATCC_1997 DQAKRVADQLITNGRATHASLGVRVG----------NDKEVQGARIVEVV
TH_2973|M.thermoresistible__bu ATAIDAADQMLADGRVTHPFLGVSLARLTPSIRRQLNVGAEDGALVTVVD
.: :: * :. :*: . ** :. *
MMAR_4214|M.marinum_M AGSPAQKAGILENDVIVKIGNRSVADSDEFVVAVRQLTIGQDAPVEVVR-
MUL_4517|M.ulcerans_Agy99 AGSPAQKAGILENDVIVKIGNRSVADSDEFVVAVRQLTIGQDAPVEVVR-
Rv1223|M.tuberculosis_H37Rv AGSPAQKGGILENDVIVKVGNRAVADSDEFVVAVRQLAIGQDAPIEVVR-
MLBr_01078|M.leprae_Br4923 AGSPAQKGGILENDVIVKVGNRKVADADEFIVAVRQLTIGQDASVEVVR-
MAV_1366|M.avium_104 AGSPAQKGGVLENDVVVKVGNRKVADADEFVVAVRQLTIGQDSPIEVVR-
Mflv_1889|M.gilvum_PYR-GCK AGGAASAAGLPSGVIVTKLDDRAISSADALVAAVRSKAPGDKVTLTYQD-
Mvan_4842|M.vanbaalenii_PYR-1 AGGAASAAGLPSGVIVTKVDDRLINSADALVAAVRSKAPGDKVTLTYLD-
MSMEG_5486|M.smegmatis_MC2_155 DGGAAAAAGLPSGVVVTKVDDRVIGSADALVAAVRSKAPGEKVTLTYLD-
Mb1009|M.bovis_AF2122/97 AGGAAANAGVPKGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQD-
MAB_1078|M.abscessus_ATCC_1997 AGGAAEKAGIPNGAVVTKVDNRPVNSADGLVAAVRSKAPGDKVTLTYTDG
TH_2973|M.thermoresistible__bu RGAPAAEAGLRPGDVIVEFDGKQVRNVEDLLTALRQSRPGARVQVVFIR-
*..* .*: . ::.:...: : . : ::.*:*. * :
MMAR_4214|M.marinum_M -DGRHVTLTVKPDPDSS
MUL_4517|M.ulcerans_Agy99 -DGRHVTLTVKPDPDSS
Rv1223|M.tuberculosis_H37Rv -EGRHVTLTVKPDPDST
MLBr_01078|M.leprae_Br4923 -DGRHVTLTVKSDPDSS
MAV_1366|M.avium_104 -DGRHVTLTVKPDPDGS
Mflv_1889|M.gilvum_PYR-GCK ASGKPRTVDVTLGKAKQ
Mvan_4842|M.vanbaalenii_PYR-1 PAGKSQSLDVTLGKAGQ
MSMEG_5486|M.smegmatis_MC2_155 QAGKPQTVDVTLGKAEQ
Mb1009|M.bovis_AF2122/97 PSGGSRTVQVTLGKAEQ
MAB_1078|M.abscessus_ATCC_1997 NGGQEKTADVTLGEVAR
TH_2973|M.thermoresistible__bu -GGQRQQVTLTVGSRN-
* :. .