For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2903 | - | - | 100% (184) | conserved hypothetical protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0231c | - | 2e-39 | 50.00% (186) | transmembrane protein |
M. gilvum PYR-GCK | Mflv_0422 | - | 4e-48 | 59.76% (169) | hypothetical protein Mflv_0422 |
M. tuberculosis H37Rv | Rv0226c | - | 2e-39 | 50.00% (186) | transmembrane protein |
M. leprae Br4923 | MLBr_02582 | - | 2e-35 | 47.25% (182) | hypothetical protein MLBr_02582 |
M. abscessus ATCC 19977 | MAB_4475 | - | 2e-39 | 45.18% (197) | hypothetical protein MAB_4475 |
M. marinum M | MMAR_0475 | - | 7e-39 | 47.89% (190) | transmembrane protein |
M. avium 104 | MAV_4944 | - | 9e-44 | 50.26% (191) | hypothetical protein MAV_4944 |
M. smegmatis MC2 155 | MSMEG_0315 | - | 2e-39 | 46.77% (186) | transmembrane protein |
M. ulcerans Agy99 | MUL_1125 | - | 2e-38 | 46.84% (190) | transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_0249 | - | 7e-56 | 60.11% (183) | hypothetical protein Mvan_0249 |
CLUSTAL 2.0.9 multiple sequence alignment Mb0231c|M.bovis_AF2122/97 ------------------MRWFRPGYALVLVLLLAAPLLRPGYLLLRDAV Rv0226c|M.tuberculosis_H37Rv ------------------MRWFRPGYALVLVLLLAAPLLRPGYLLLRDAV MMAR_0475|M.marinum_M MRAKMARGEGAGWASPRCACWWRPGYALVLALLVVGPVLGPGYLLLRDAV MUL_1125|M.ulcerans_Agy99 ----MARGEGAGWASPRCACWWRPRYALVLALLVVGPVLGPGYLLLRDAV MAV_4944|M.avium_104 ------------------MRWTRPGYALVLALLVVGPLLRPGYLLLRDAV MLBr_02582|M.leprae_Br4923 ---------MSRELYHRSMSWSRPSYALGMALLVVGPLMRPGYLLLRDAV MSMEG_0315|M.smegmatis_MC2_155 ----------------------MPAYALVLSVLVTAPLLAPGYLLLRDAV MAB_4475|M.abscessus_ATCC_1997 ---------------MRRIGLIPPLYALALAAAVTAPLAAPGYLLIRDAV Mflv_0422|M.gilvum_PYR-GCK ---------------------MAPAYALALTVAVTAPLLQPGYLLLRDAV Mvan_0249|M.vanbaalenii_PYR-1 -----------------------------MTLGVTAPLLAPGHLLLRDAV TH_2903|M.thermoresistible__bu -------------------------------------------------- Mb0231c|M.bovis_AF2122/97 STPRSYVSANALGLT-SAPRATPQDFAVALASHLVDGGVVVKALLLLGLW Rv0226c|M.tuberculosis_H37Rv STPRSYVSANALGLT-SAPRATPQDFAVALASHLVDGGVVVKALLLLGLW MMAR_0475|M.marinum_M STPRSYLSDSALGLM-AAPRATPQDFAIALASQVIDGGILVKALLVLGLW MUL_1125|M.ulcerans_Agy99 STPRSYLSDSALGLM-AAPRATPQDFAIALASQVIDGGILVKALLVLGLW MAV_4944|M.avium_104 STPRSYLSDTALGLT-AAPRAVPQDFAVALASHLLDGGVVVKTLLLLGLW MLBr_02582|M.leprae_Br4923 STPRSYLSDAALGLT-SAPRSTPQDFAVAMASHLVDGGIVVKSALVLGLW MSMEG_0315|M.smegmatis_MC2_155 STPRSYVTDAALGLTEAAPRALPQDFAVALASSVLDGGVVVKALLLAGLA MAB_4475|M.abscessus_ATCC_1997 STPRSYVTDTALGVGEAAPRAVPQDFFIAVMTVLVDGGVLVKMLLALGLW Mflv_0422|M.gilvum_PYR-GCK STPRSYLTDAALGLTQAAPRALPQDFLVALVSTVVDGGVVVKALLMLGLW Mvan_0249|M.vanbaalenii_PYR-1 STPRSYLTDGALGLTQAAPRALPQDFAVALASTVVDGGVVVKALLMLGLW TH_2903|M.thermoresistible__bu -------------------------------------------------- Mb0231c|M.bovis_AF2122/97 LAGWGAARLVATALPAAGAAGQFVAITLAIWNPYVAERLLQGHWSLLVGY Rv0226c|M.tuberculosis_H37Rv LAGWGAARLVATALPAAGAAGQFVAITLAIWNPYVAERLLQGHWSLLVGY MMAR_0475|M.marinum_M LAGWGAAVLVARALPAAGAGGQFVAITLAIWNPYVAERLLQGHWSLLLGY MUL_1125|M.ulcerans_Agy99 LAGWGAAVLVARALPAADAGGQFVAITLAIWNPYVAERLLQGHWSLLLGY MAV_4944|M.avium_104 LAGWGAARLVALVLPGAGMPGEFVATTLAIWNPYVAERLLQGHWSLLVGY MLBr_02582|M.leprae_Br4923 LAGWGAARLVVTALPSAGVAGQFVASTLAVWNPYVAERLLQGHWSLLVGY MSMEG_0315|M.smegmatis_MC2_155 AAGWGAARLVGHVLFDAGLAGRFTAATLAIWNPYVAERLLQGHWSLLVGY MAB_4475|M.abscessus_ATCC_1997 LAGWGAARLAAQLVPAAGIPGELVAATIAIWNPYVAERLLQGHWSLLVGY Mflv_0422|M.gilvum_PYR-GCK LAGWGAARLVAEVL-QAGVAGQCVAVTIAIWNPYVAERLLQGHWSLLVGY Mvan_0249|M.vanbaalenii_PYR-1 LAGWGAARLVATVLPDAGTAGQCVAVTIAIWNPYVAERLLQGHWSLLVGY TH_2903|M.thermoresistible__bu -------------------------------------------------- Mb0231c|M.bovis_AF2122/97 GCLPWVATAMLT-----------------MRTTVGAG--------WFGLF Rv0226c|M.tuberculosis_H37Rv GCLPWVATAMLT-----------------MRTTVGAG--------WFGLF MMAR_0475|M.marinum_M GCLPWVAATMLG-----------------LRASEAS---------QTGFF MUL_1125|M.ulcerans_Agy99 GCLPWVAATMLG-----------------LRAPEAS---------QTGFF MAV_4944|M.avium_104 GCLPWVATAMLG-----------------LRTGGAG------------FF MLBr_02582|M.leprae_Br4923 GCLPWVAEAMLM-----------------LRSSDNASR-----PGLLGFF MSMEG_0315|M.smegmatis_MC2_155 GCLPWVAVSVLR-----------------LRERASWT----------PVA MAB_4475|M.abscessus_ATCC_1997 GCLPWIALTVIR-----------------LRTATNLG----------AWC Mflv_0422|M.gilvum_PYR-GCK GCLPWVAVSMLSLRAGSPRMSMSPPAAPNLHSSRQSASRRLLECNFGGVA Mvan_0249|M.vanbaalenii_PYR-1 GCLPWVALCF----------------APKLHSSSGSASGPLLECNFGRVG TH_2903|M.thermoresistible__bu -------------------------------------------------- Mb0231c|M.bovis_AF2122/97 GLAFWVALAGLTPSGLLLAATVAVVCVAMPGAG----RPRWQCGVAALGS Rv0226c|M.tuberculosis_H37Rv GLAFWVALAGLTPSGLLLAATVAVVCVAMPGAG----RPRWQCGVAALGS MMAR_0475|M.marinum_M GLAFWIALAGLTPTGLLLAATVALTCVAAPGGG----KPRWLCATAALTA MUL_1125|M.ulcerans_Agy99 GLAFWIALAGLTPTGLLLAATVALTCVAAPGGG----KPRWLCATAALAA MAV_4944|M.avium_104 GLAFFIALAGLTPTGLLLAAAVALACVPVAGAG----RRRWVWAAAAIGA MLBr_02582|M.leprae_Br4923 ALACWIALAGLTPTGLMLAATVALICVAVPVEGPGEPRPRWLCAAATLGS MSMEG_0315|M.smegmatis_MC2_155 PLVFWMALAGLTPTGLVLAATVALVCVAAPGDG----WRRARVAGLGLGV MAB_4475|M.abscessus_ATCC_1997 PLAFWIAVAGLTPTGTVLALIVGLAAATDRRSR-----------VGVLAI Mflv_0422|M.gilvum_PYR-GCK AVVFWVALAGLTPTGLMLAATIALTCALAPGAG----RPRWWCAAVGMAA Mvan_0249|M.vanbaalenii_PYR-1 ALLFWIALAGLTPTGLMLAATIALACSMA--AG----RSRWRCAGLSLAA TH_2903|M.thermoresistible__bu -------------------------------------------------- Mb0231c|M.bovis_AF2122/97 ALVGALPWLTASALGSSLTSHTAANQLGVTAFAPRAEPGLGTLGSLASLG Rv0226c|M.tuberculosis_H37Rv ALVGALPWLTASALGSSLTSHTAANQLGVTAFAPRAEPGLGTLGSLASLG MMAR_0475|M.marinum_M ALVGALPWLTASALGSSLTTHTAANGLGVAAFAPRAEPGLGTLLSLASLG MUL_1125|M.ulcerans_Agy99 ALVGALPWLTASALGSSLTTHTAANGLGVAAFAPRAEPGLGTLLSLASLG MAV_4944|M.avium_104 AAVAALPWLVAAVTGAALPSHTPANRLGVEAFAPRAEPGLGTLTSLASLG MLBr_02582|M.leprae_Br4923 ALGAALPWLTASAVGTSLTAHTVANTLGVTVFAPRAEPGLGTLASLASLG MSMEG_0315|M.smegmatis_MC2_155 AVAAACPWLVAAFVSGAVSSSPDP-GAGVRAFAARAEPGLATLGSLAGLG MAB_4475|M.abscessus_ATCC_1997 SVLAAMPWLVASGLGAAVP---AGDAAGVHAFAARAEPGLGTLGSLASLG Mflv_0422|M.gilvum_PYR-GCK ALAAALPWLVATVVAPGWAAADAGQKAGVEAFAARAEPGLGTLGTLAGLG Mvan_0249|M.vanbaalenii_PYR-1 SMIAALPWLVASAVGGGWAAAAD-QQPGVAAFAARAEPGLATLGSLASLG TH_2903|M.thermoresistible__bu -------------------------------------------------- Mb0231c|M.bovis_AF2122/97 GIWNGEAVPSSRTTLFAVASAVVLLAMVAIGLPTVARRPVAVPLLTLAAV Rv0226c|M.tuberculosis_H37Rv GIWNGEAVPSSRTTLFAVASAVVLLAMVAIGLPTVARRPVAVPLLTLAAV MMAR_0475|M.marinum_M GIWNGDAVPGSRTTLFAVASAAVLLVVVAVGLPTVARRPALVPLLVLAAV MUL_1125|M.ulcerans_Agy99 GIWNGDAVPGSRTTLFAVASAAVLLVVVAVGLPTVARRPALVPLLVLAAV MAV_4944|M.avium_104 GIWNADAVPGSRTTLFAVASAVVLLGVVAVGLPAVARRPAAVPLLVLAAA MLBr_02582|M.leprae_Br4923 GIWNGEAVPTSRTTLFAVLSATVLLGVVVAGLPVAVRRPAVVPLLVLAAV MSMEG_0315|M.smegmatis_MC2_155 GIWNGDAVPASRTSLFAVVATVVLLGVVAAGLPVVARRRAAVPLLVLAAG MAB_4475|M.abscessus_ATCC_1997 GMWNASAVPASRTTLFALVFSVVLLIVVAVGAAVLWRARKALGLLGIAVA Mflv_0422|M.gilvum_PYR-GCK GIWNADAVPASRTTLFAIVSTVVLLAIVAVGVPLLVRRRVPVPLLVLAVV Mvan_0249|M.vanbaalenii_PYR-1 GIWNAEAVPASRTTLFALASAGVLLAIVAAGVPLLIRRRTALPLLVVAAA TH_2903|M.thermoresistible__bu -------------------------------------------------- Mb0231c|M.bovis_AF2122/97 SVMVPAVLATGPGLHALRVVVDAAPGLGVLRDGQKWVALAVPGYTLSGAG Rv0226c|M.tuberculosis_H37Rv SVMVPAVLATGPGLHALRVVVDAAPGLGVLRDGQKWVALAVPGYTLSGAG MMAR_0475|M.marinum_M SVLVPAALATGPGLHILAAAVDAAPGLGVLRDGQKWVALAMPGYAVSAAA MUL_1125|M.ulcerans_Agy99 SVLVPAALATGPGLHILAAAVDAAPGLGVLRDGQKWVALAMPGYAVSAAA MAV_4944|M.avium_104 AVLIPAGLATGPGLRLLGAVVDAAPGVGVLRDGQKWVALAVPGYALAGAG MLBr_02582|M.leprae_Br4923 AVATPAALATGPGIDMLKAVVNAVPGLGVLRDGQKWVALAVPGYSLAGAG MSMEG_0315|M.smegmatis_MC2_155 AVIMPALMASAPGLVVVEALIDAVPGLGIVRDGQKWVALAMPGYALAAGA MAB_4475|M.abscessus_ATCC_1997 AVIIPALLATGPGLTLTTWLITEVPGLGILRDGQKWVALAMPAYAVAGAA Mflv_0422|M.gilvum_PYR-GCK AVVAPALMATGPGLLAVEAVIGAVPGLGVLRDGQKWVALAMPAYALAGAA Mvan_0249|M.vanbaalenii_PYR-1 AVVIPTLMATGPGLAAVDAVIGAVPGLGVIRDGQKWVALAMPAYALAGAA TH_2903|M.thermoresistible__bu -------------------------------------------------- Mb0231c|M.bovis_AF2122/97 TVLTLRRWLRPAT------AAVVCCLALVLTLPDLAWGVWGKVAPVHYPS Rv0226c|M.tuberculosis_H37Rv TVLTLRRWLRPAT------AAVVCCLALVLTLPDLAWGVWGKVAPVHYPS MMAR_0475|M.marinum_M AVSTLSRCKTAATPLKSTLAASACCLALVLALPDLAWGVLGRVAPVHYPP MUL_1125|M.ulcerans_Agy99 AVSTLSRCKTAATPLKSTLAASACCLALVLALPDLAWGVLGRAAPVHYPP MAV_4944|M.avium_104 AVLTLRRRLFGAAA-----PALVCCLALILALPDLVWGVGGRVSPVRYPR MLBr_02582|M.leprae_Br4923 AVVTLGRWLRPSRPLSPVVTALACCLALILALPDLAWGVWGKVQPVHYPS MSMEG_0315|M.smegmatis_MC2_155 APMMLRRLRIPAAA-----AAAVCCAALIAVLPDLTWGVGNQMRAVRYPQ MAB_4475|M.abscessus_ATCC_1997 AVIAVRERSSQYL------AAGLACAALIFTLPDLAWGVGGRMTAVKYPS Mflv_0422|M.gilvum_PYR-GCK TVLTLRSRIPTLA------TGAVCCAALIATLPDLAWGVGGRVTPVDYPP Mvan_0249|M.vanbaalenii_PYR-1 AVIALRPRVPAAA------TAAVFAAALVATLPDLAWGVGGRVNPVQYPA TH_2903|M.thermoresistible__bu --------------------------------------VGGQLGSVRYPP * .: .* ** Mb0231c|M.bovis_AF2122/97 GWAAVAAAIN---ADPRTVAVLPAGTMRRFSWSGS--------APVLDPL Rv0226c|M.tuberculosis_H37Rv GWAAVAAAIN---ADPRTVAVLPAGTMRRFSWSGS--------APVLDPL MMAR_0475|M.marinum_M GWTAVATAIN---HQPGTVAVLPIGTMRRFSWAGR--------APVLDPL MUL_1125|M.ulcerans_Agy99 GWTAVATAIN---HQPGTVAVLPIGTMRRFSWSGR--------APVLDPL MAV_4944|M.avium_104 GWPAVAAAIN---ARPDAVAVLPAGTMRLFSWSGP--------APVLDPL MLBr_02582|M.leprae_Br4923 GWAAVAATINDRGEGPGWVAVLPAGTMRRFSWSGT--------APVLDPL MSMEG_0315|M.smegmatis_MC2_155 SWAQVAATIN---ADPRPVVALPADSIREFSWAG----------TVLDPL MAB_4475|M.abscessus_ATCC_1997 GWNAVAAHIN---ADPHPVAVLPPETMRQYPWGPSS-------IPVLDPF Mflv_0422|M.gilvum_PYR-GCK GWSAAAAVIN---ADPATVAVLPVDSMRRFAWAPG--------APVLDPL Mvan_0249|M.vanbaalenii_PYR-1 GWSAAAAVIN---ADPAPVAVLPVDSMRHFSWAGE--------VPVLDPL TH_2903|M.thermoresistible__bu AWPAAAAMIN---ADPRPVAVLPPDVMRTFAWTRPGLGADAGPAPVLDPL .* .*: ** * *..** :* :.* .****: Mb0231c|M.bovis_AF2122/97 PRWVRADVLTTGDLVISGVTVPGEDAHARAVQELLLTGPHPSTLAAAGVG Rv0226c|M.tuberculosis_H37Rv PRWVRADVLTTGDLVISGVTVPGEDAHARAVQELLLTGPHPSTLAAAGVG MMAR_0475|M.marinum_M PRWVRPDVLSSGDLVISGVLVPGDGVRARTVQKLLLAGADPAALAQAGVG MUL_1125|M.ulcerans_Agy99 PRWVRPDVLSSGDLVISGVLVPGDGVRARTVQKLLLAGADPEALAQAGVG MAV_4944|M.avium_104 PRWVRADVLSTGDLVISGTTIAGEGAHARAVQELLLSGPDPAALAAAGVG MLBr_02582|M.leprae_Br4923 PRWVRDDVLTTGDLIISGVMVAGEGNHARAAQDLLLSGPNPSALTAAGVA MSMEG_0315|M.smegmatis_MC2_155 PRWLRADVLTTGDLLIGGRTVPGEGARARAVQGLLRDGASPQQLAEAGVG MAB_4475|M.abscessus_ATCC_1997 PRWIRADTVSSGDLRVDGHDVRGDGTRGRQVEELLRAGAAPRELAAHGVG Mflv_0422|M.gilvum_PYR-GCK PRWLRADVLSTGDLTIAGTTVLGEGARAREVQQMLASGADRDELAAAGVG Mvan_0249|M.vanbaalenii_PYR-1 PRWVRADVLSTGDLTIAGRTVPGEGTRAREVQQMLISGADADQLAAAGVG TH_2903|M.thermoresistible__bu PRWVRAEVLATGDLRVGERTVPGEGRHARKVQDLLLSGADAAALTAAGVG ***:* :.:::*** : : *:. :.* .: :* *. *: **. Mb0231c|M.bovis_AF2122/97 WLVVESDSAGDMGAAARTLGRLAAAHRDDELALYRVGG-QTSG-ASSARL Rv0226c|M.tuberculosis_H37Rv WLVVESDSAGDMGAAARTLGRLAAAHRDDELALYRVGG-QTSG-ASSARL MMAR_0475|M.marinum_M WLVVEVHGGGEVGEAGRTLDRLTPTYRDDELALYRIGG-RSAG-VPAGDR MUL_1125|M.ulcerans_Agy99 WLVVEVHGGGEVGEAGRTLDRLTPTYRDDELALYRIGG-RSAG-VPAGDR MAV_4944|M.avium_104 WLVLEADSAGEVGAAAHTLGAAAPVYRDDEIALYRIGG-HTAG-VAADRR MLBr_02582|M.leprae_Br4923 WLVVESDTAGDMGASARTLAALQPTYRDDAIGLYRIGG-SNAKTAPSPYR MSMEG_0315|M.smegmatis_MC2_155 WLVRETDSG---------------------ITAQRIGG-EAPS---SPHR MAB_4475|M.abscessus_ATCC_1997 WVVVQADTPGQQAVSSKTLAQLDTAYRDGDIALYRVPGPWNPIAAPPGRR Mflv_0422|M.gilvum_PYR-GCK WVVVEGSG---------VRLALPESYRDENLTVYRVGG-DSPS---SAHR Mvan_0249|M.vanbaalenii_PYR-1 WVVVEGTADG------TPELRLPVAYRDDDLTVYAVGG-DAAG---SPHR TH_2903|M.thermoresistible__bu WVVVENPGDS-------PDLDLPVAYRDADLAVYRVSG-DRPG---SPYR *:* : : : * . . Mb0231c|M.bovis_AF2122/97 KATMLAHWAWLSMLLVGGAG-AAGYWVRRHLHHCEDTPASRAQD--- Rv0226c|M.tuberculosis_H37Rv KATMLAHWAWLSMLLVGGAG-AAGYWVRRHLHHCEDTPASRAQD--- MMAR_0475|M.marinum_M RAMMLAHWAWLSMLLAGGAG-MAAGRVRRHLSGREESPTDLAAD--- MUL_1125|M.ulcerans_Agy99 RAMMLAHWAWLSMLLAGGAG-MAAGLVRRHLSGREESPTDLAAD--- MAV_4944|M.avium_104 AATLIAHLAWLVLLLGSGAGVLLGAWWRRGVSRAR------------ MLBr_02582|M.leprae_Br4923 GLLIAAHLTWLVILVMAVVG----MQITRHTHFRDVSSVALLSRR-- MSMEG_0315|M.smegmatis_MC2_155 GLLIAAHLVWLAALAGGALG-LVAGRVGRVLSRRTWRHRPRPG---- MAB_4475|M.abscessus_ATCC_1997 AAVIAAHLVWIALLAAGGVAVFRRQHTRQVGSGGTQDPKICTPDSDN Mflv_0422|M.gilvum_PYR-GCK GVVIAAHSVWLAALGVGFLGMLVARRRSRRAHGREQEVDRPQAGDQ- Mvan_0249|M.vanbaalenii_PYR-1 TVLLAAHTVWLAALGAGLIAMLVGLLRSRHAHRRQQDVDGPERGDQ- TH_2903|M.thermoresistible__bu PVMIAAHLVWVGVLLGGFAAMARSVWSRRVAARRD------------ : ** .*: * . . :