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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2582 | - | - | 100% (369) | putative alpha/beta hydrolase fold |
M. thermoresistible (build 8) | TH_0992 | ephA | 2e-56 | 38.35% (339) | PROBABLE EPOXIDE HYDROLASE EPHA (EPOXIDE HYDRATASE) |
M. thermoresistible (build 8) | TH_0963 | ephE | 3e-16 | 36.50% (137) | POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1973 | ephB | 1e-76 | 40.46% (351) | epoxide hydrolase EphB |
M. gilvum PYR-GCK | Mflv_1415 | - | 2e-46 | 34.46% (325) | alpha/beta hydrolase fold |
M. tuberculosis H37Rv | Rv1938 | ephB | 1e-76 | 40.46% (351) | epoxide hydrolase EphB |
M. leprae Br4923 | MLBr_02297 | - | 1e-14 | 33.33% (135) | putative hydrolase |
M. abscessus ATCC 19977 | MAB_0528c | - | 1e-52 | 36.47% (329) | epoxide hydrolase EphA |
M. marinum M | MMAR_2866 | ephB | 6e-77 | 41.21% (347) | epoxide hydrolase EphB |
M. avium 104 | MAV_0539 | - | 2e-51 | 36.87% (339) | hydrolase, alpha/beta fold family protein |
M. smegmatis MC2 155 | MSMEG_6106 | - | 3e-55 | 37.88% (330) | epoxide hydrolase |
M. ulcerans Agy99 | MUL_2888 | ephB | 7e-76 | 41.21% (347) | epoxide hydrolase EphB |
M. vanbaalenii PYR-1 | Mvan_4002 | - | 2e-78 | 41.38% (348) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment Mb1973|M.bovis_AF2122/97 MS----------------QVHRILNCRGTRIHAVADSP----------PD Rv1938|M.tuberculosis_H37Rv MS----------------QVHRILNCRGTRIHAVADSP----------PD MMAR_2866|M.marinum_M MA----------------QAHRILNCRGTRIHAVEDG------------- MUL_2888|M.ulcerans_Agy99 MA----------------QAHRILNCRGTRIHAVEDG------------- Mvan_4002|M.vanbaalenii_PYR-1 MS----------------QIHRMLNCRGTRIHAVEEG------------- TH_2582|M.thermoresistible__bu MSNTVAAPRCEIVTEADGYDHATIFAGDQRLHVVVKG------------- MAV_0539|M.avium_104 ----------------------------MRLRVTEAG------------D MSMEG_6106|M.smegmatis_MC2_155 ---------------MITPTERSVETNGVTLRVTEAG------------E MAB_0528c|M.abscessus_ATCC_199 MT-----------DAAVDIRERDIATNGVHLRIVEAG------------E Mflv_1415|M.gilvum_PYR-GCK ------------------MQSRMVHTNGITLRVFEAG------------E MLBr_02297|M.leprae_Br4923 ----MAMSNPSVTRIAGPWHHLDVHANGIRFHVVEAVPTQPAGQDCAPSA :: Mb1973|M.bovis_AF2122/97 QQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQ Rv1938|M.tuberculosis_H37Rv QQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQ MMAR_2866|M.marinum_M -EGPLVILLHGFPESWYSWRHQIPALAAAGYRVVAVDQRGYGRSSKYRVQ MUL_2888|M.ulcerans_Agy99 -EGPLVILLHGFPESWYSWRHQIPALAAADYRVVAVDQRGYGRSSKYRVQ Mvan_4002|M.vanbaalenii_PYR-1 -EGPLVVLIHGFPESWYSWRHQIPALAAAGYRVVAIDQRGYGRSSKYRVQ TH_2582|M.thermoresistible__bu -SGPLVLLVHGFPESWFCWREQIDAIAARGYRVAAPDMRGYGRSGKPAAV MAV_0539|M.avium_104 RGAPVVILAHGFPELAYSWRHQIDVLADAGYHVLAPDQRGYGGSDRPDAV MSMEG_6106|M.smegmatis_MC2_155 RGNPVVVLAHGFPELAYSWRHQIPALAAAGYHVLAPDQRGYGGSSRPESI MAB_0528c|M.abscessus_ATCC_199 PGQPAVILSHGFPELAYSWRHQIPALAAAGYHVIAPDQRGYGRSSMPAHI Mflv_1415|M.gilvum_PYR-GCK RSAPVVVLCHGFPELAFTWRHQISALAAAGFHVLAPDQRGYGGSDKPGDA MLBr_02297|M.leprae_Br4923 TARPLVMLLHGFGSFWWSWRHQLRGLTEA--RLVAVDLRGYGGSDKPP-- * *:* *** . : **.*: :: :: * * **** *. Mb1973|M.bovis_AF2122/97 KAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV Rv1938|M.tuberculosis_H37Rv KAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV MMAR_2866|M.marinum_M KAYRIKELVGDVLGLVDAYGADKAFVIGHDWGAPVAWTFAWLYPQRCAGV MUL_2888|M.ulcerans_Agy99 KAYRIKELVGDVLGVVDAYGADKAFVIGHDWGAPVAWTFAWLYPQRCAGV Mvan_4002|M.vanbaalenii_PYR-1 KAYRIKELVGDIVGVIDAYGVERAVVVGHDWGAPVAWTFAWLHPQRCAGV TH_2582|M.thermoresistible__bu EDYSILKLVDDCVAIVTALGAEEATIVGHDWGSMVAWTAAWTRPEVFTAV MAV_0539|M.avium_104 EAYDIHQLTADLVGLLDDVGAQRAVWVGHDWGAAVVWNAPLLHPDRVAAV MSMEG_6106|M.smegmatis_MC2_155 DDYDITKLTGDVVGLLDDIGAEHAAVIGHDWGAVVAWNAAQLHPDRVAAV MAB_0528c|M.abscessus_ATCC_199 DDYNIEALSDDLLGILDDVGAGKATFVGHDWGAVVTWHTALAVPERVSGV Mflv_1415|M.gilvum_PYR-GCK GVYNVAELTADVVGLLDDVGAERAALVGHDFGAVVAWGAPLLEPDRFSAV MLBr_02297|M.leprae_Br4923 RGYDGWTLAGDTAGLIRALGHSSATLVGHAEGGLACWATALLHPRLVRAI * * * .:: * * :** *. . * . * .: Mb1973|M.bovis_AF2122/97 VGISVPFAGRGVIGLPGSP-FGERRPSDYHLELAGPGRVWYQDYFAVQDG Rv1938|M.tuberculosis_H37Rv VGISVPFAGRGVIGLPGSP-FGERRPSDYHLELAGPGRVWYQDYFAVQDG MMAR_2866|M.marinum_M VGISVPFAGRGVIGLPGSP-FGEHRPNDYHLELAGEGRVWYQDYFSAQDG MUL_2888|M.ulcerans_Agy99 VGISVPFAGRGVIGLPGSP-FGEHRPNDYHLELAGEGRVWYQD-FSAQDG Mvan_4002|M.vanbaalenii_PYR-1 AGISVPFAGRGVIGLPGSP-FGEHRPDDYHLELAGPGRVWYQDYFSAQDG TH_2582|M.thermoresistible__bu IGMSVAFGGRGLIPIAGVDSFGTRRPSEVQREIAGPDKVFYQEYWVQKGA MAV_0539|M.avium_104 AAMSVPVTPR-----------PRLAPTQAWRKMFGEN-FFYILYFQEPGV MSMEG_6106|M.smegmatis_MC2_155 GGLSVPPTPR-----------STRPPTQAFRELVGEGKFFYILHFQEPGV MAB_0528c|M.abscessus_ATCC_199 VGLSVPFTRR-----------SQVPPTQAWNKLFGDN-FFYILYFQEPGV Mflv_1415|M.gilvum_PYR-GCK AGLSLPPVPR-----------PQVPTTQAFRRVFGDR-FMYILYFQEPGP MLBr_02297|M.leprae_Br4923 ALINSPHPAA-------------LRRSMLTHRNQGYALLPTLLRYQLPIW :. . . * . : Mb1973|M.bovis_AF2122/97 IITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRA Rv1938|M.tuberculosis_H37Rv IITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRA MMAR_2866|M.marinum_M IIAEIEEDVRTWLLGLTYTVSGDGMIAATKAAADAGVDLASMDPIDVIRA MUL_2888|M.ulcerans_Agy99 IIAEIEEDVRTWLLGLTYTVSGDGMIAATKAAADAGVDLASMDPIDVIRA Mvan_4002|M.vanbaalenii_PYR-1 IIAEIEEDLRGWLWGLTYTVSGDGMIAATKAAVAAGVDLESMDPIDVIRA TH_2582|M.thermoresistible__bu LESEFEADPRGFLRDQYYSFS-AGPFPPDYQAPNP-LEADPAEVAEQTRS MAV_0539|M.avium_104 ADAELNADPAQVMRRMMGSLRTDGDKAAGLRMVA---------------- MSMEG_6106|M.smegmatis_MC2_155 ADAEFDGDPARALRRMFGGLLPPENEEAAMRMLR---------------- MAB_0528c|M.abscessus_ATCC_199 ADADLNRDPATTMRRMMAGMAR----IDGATMIA---------------- Mflv_1415|M.gilvum_PYR-GCK ADAELARDPATTFRRLFALTTG------GAEMVGD--------------- MLBr_02297|M.leprae_Br4923 PERLLTRNNAAEIERLVRSRSS---------------------------- : : : Mb1973|M.bovis_AF2122/97 GPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYH Rv1938|M.tuberculosis_H37Rv GPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYH MMAR_2866|M.marinum_M GPLCMADGARLKDAFVYPETMPAWFTDADLDFYTGEFERSGFGGPLSFYH MUL_2888|M.ulcerans_Agy99 GPLCMADGARLKDAFVYPETMPAWFTDADLDFYTGEFERSGFGGPLSFYH Mvan_4002|M.vanbaalenii_PYR-1 GPLCMAEGARLKDAFSYPETMPDWFTEDDLDFYTAEFERSGFGGPLSFYH TH_2582|M.thermoresistible__bu GGACLDPGAKMRDGLLTPDPVPDWL-AADLDEYVAEFERTGLEAPLNWYR MAV_0539|M.avium_104 -----PGPEGFLERLPEPDGLPEWISQDELDHYIAEFSRTGFTGGLNWYR MSMEG_6106|M.smegmatis_MC2_155 -----PGPEGLIDRLPEPSALPDWISTGEFDHYVDAFTRTGFTGGLNWYR MAB_0528c|M.abscessus_ATCC_199 -----PGPAGFVERMPDPGELPEWLSQDELDHYITEFARTGFTGGLNWYR Mflv_1415|M.gilvum_PYR-GCK -----AGPQGFLDRIPEPGGLPDWISQADFDVYVDEFTRGGFTGPLNWYR MLBr_02297|M.leprae_Br4923 -----AKWQACEDFAVTIDHLRIAIQIPAAAHCALEYQRWAVR------S : : : : * .. Mb1973|M.bovis_AF2122/97 NIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPNYR Rv1938|M.tuberculosis_H37Rv NIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPNYR MMAR_2866|M.marinum_M NIDNDWHDLADQEGKPLSAPALFIGGQYDVGTTWGAEAIARAHEVMSDYR MUL_2888|M.ulcerans_Agy99 NIDNDWHDLADQEGKPLSAPALFIGGQYDVGTTWGAEAIARAHEVMSDYR Mvan_4002|M.vanbaalenii_PYR-1 NIDNDWHDLAEQAGTPLTPPAVFIGGQYDVGTTWGAEALERAPEVMPNYC TH_2582|M.thermoresistible__bu AMDLSWEELEPYADRPIEVPALFIGADLDVATQWSVEAVAAFDRTVPKHR MAV_0539|M.avium_104 NFDRNWETTPELDGAKIAVPCLFIGGTADP--VLSFTRADRAAEVISGPY MSMEG_6106|M.smegmatis_MC2_155 NFDRNWELTAHLADAKITVPALFLAGAADP--VLGFARPDRARDLIAGPY MAB_0528c|M.abscessus_ATCC_199 NFDRNWALTERLAGANVVVPSLFIAGAADP--VLGFTDHAGSAKYRTDNR Mflv_1415|M.gilvum_PYR-GCK CFDRNWELTAETPAPTIEVPALFVGGTEDA--TLAYTPRDRVREVVTGDY MLBr_02297|M.leprae_Br4923 QLRNEGRKFMKSMSRPFSVPLLHVRGDADP--YLLADSVDRTRRYAPHG- : . . * :.: . * . Mb1973|M.bovis_AF2122/97 GTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP---- Rv1938|M.tuberculosis_H37Rv GTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP---- MMAR_2866|M.marinum_M GTHMVADVGHWIQQEAPDETNRLLLEFLGGLRQ---- MUL_2888|M.ulcerans_Agy99 GTHMVADVGHWIQQEAPDETNRLLLEFLGGLRQ---- Mvan_4002|M.vanbaalenii_PYR-1 GTHMVPDVGHWIQQEAPEETNRLLLDFLRGLG----- TH_2582|M.thermoresistible__bu PSVILQNCGHWFTRERPAETTAAILEFLEGLGHGR-- MAV_0539|M.avium_104 RHVMIDGAGHWLQQERPAEVNAALLDFLNGLELR--- MSMEG_6106|M.smegmatis_MC2_155 TEILLDGAGHWVQQERAEEVNAALIGFLHGLELQ--- MAB_0528c|M.abscessus_ATCC_199 GDLLIDGAGHWIQQERPLEVNAALLAFLREVVH---- Mflv_1415|M.gilvum_PYR-GCK REVMIDGAGHWLTEERPDEVSRVLVDFLTTVR----- MLBr_02297|M.leprae_Br4923 RYVSVSDAGHFSHEEAPEEINRYLTRFLKQVHGPRLS : . **: .* . * . : ** :