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M. thermoresistible (build 8) TH_2582 (-)

annotation: putative alpha/beta hydrolase fold
coordinates: 759341 - 760447
length: 369

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2582--100% (369)putative alpha/beta hydrolase fold
M. thermoresistible (build 8)TH_0992ephA2e-5638.35% (339) PROBABLE EPOXIDE HYDROLASE EPHA (EPOXIDE HYDRATASE)
M. thermoresistible (build 8)TH_0963ephE3e-1636.50% (137) POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1973ephB1e-7640.46% (351) epoxide hydrolase EphB
M. gilvum PYR-GCKMflv_1415-2e-4634.46% (325) alpha/beta hydrolase fold
M. tuberculosis H37RvRv1938ephB1e-7640.46% (351) epoxide hydrolase EphB
M. leprae Br4923MLBr_02297-1e-1433.33% (135) putative hydrolase
M. abscessus ATCC 19977MAB_0528c-1e-5236.47% (329) epoxide hydrolase EphA
M. marinum MMMAR_2866ephB6e-7741.21% (347) epoxide hydrolase EphB
M. avium 104MAV_0539-2e-5136.87% (339) hydrolase, alpha/beta fold family protein
M. smegmatis MC2 155MSMEG_6106-3e-5537.88% (330) epoxide hydrolase
M. ulcerans Agy99MUL_2888ephB7e-7641.21% (347) epoxide hydrolase EphB
M. vanbaalenii PYR-1Mvan_4002-2e-7841.38% (348) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mb1973|M.bovis_AF2122/97            MS----------------QVHRILNCRGTRIHAVADSP----------PD
Rv1938|M.tuberculosis_H37Rv         MS----------------QVHRILNCRGTRIHAVADSP----------PD
MMAR_2866|M.marinum_M               MA----------------QAHRILNCRGTRIHAVEDG-------------
MUL_2888|M.ulcerans_Agy99           MA----------------QAHRILNCRGTRIHAVEDG-------------
Mvan_4002|M.vanbaalenii_PYR-1       MS----------------QIHRMLNCRGTRIHAVEEG-------------
TH_2582|M.thermoresistible__bu      MSNTVAAPRCEIVTEADGYDHATIFAGDQRLHVVVKG-------------
MAV_0539|M.avium_104                ----------------------------MRLRVTEAG------------D
MSMEG_6106|M.smegmatis_MC2_155      ---------------MITPTERSVETNGVTLRVTEAG------------E
MAB_0528c|M.abscessus_ATCC_199      MT-----------DAAVDIRERDIATNGVHLRIVEAG------------E
Mflv_1415|M.gilvum_PYR-GCK          ------------------MQSRMVHTNGITLRVFEAG------------E
MLBr_02297|M.leprae_Br4923          ----MAMSNPSVTRIAGPWHHLDVHANGIRFHVVEAVPTQPAGQDCAPSA
                                                                  ::                  

Mb1973|M.bovis_AF2122/97            QQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQ
Rv1938|M.tuberculosis_H37Rv         QQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQRGYGRSSKYRVQ
MMAR_2866|M.marinum_M               -EGPLVILLHGFPESWYSWRHQIPALAAAGYRVVAVDQRGYGRSSKYRVQ
MUL_2888|M.ulcerans_Agy99           -EGPLVILLHGFPESWYSWRHQIPALAAADYRVVAVDQRGYGRSSKYRVQ
Mvan_4002|M.vanbaalenii_PYR-1       -EGPLVVLIHGFPESWYSWRHQIPALAAAGYRVVAIDQRGYGRSSKYRVQ
TH_2582|M.thermoresistible__bu      -SGPLVLLVHGFPESWFCWREQIDAIAARGYRVAAPDMRGYGRSGKPAAV
MAV_0539|M.avium_104                RGAPVVILAHGFPELAYSWRHQIDVLADAGYHVLAPDQRGYGGSDRPDAV
MSMEG_6106|M.smegmatis_MC2_155      RGNPVVVLAHGFPELAYSWRHQIPALAAAGYHVLAPDQRGYGGSSRPESI
MAB_0528c|M.abscessus_ATCC_199      PGQPAVILSHGFPELAYSWRHQIPALAAAGYHVIAPDQRGYGRSSMPAHI
Mflv_1415|M.gilvum_PYR-GCK          RSAPVVVLCHGFPELAFTWRHQISALAAAGFHVLAPDQRGYGGSDKPGDA
MLBr_02297|M.leprae_Br4923          TARPLVMLLHGFGSFWWSWRHQLRGLTEA--RLVAVDLRGYGGSDKPP--
                                       * *:* *** .  : **.*:  ::    :: * * **** *.     

Mb1973|M.bovis_AF2122/97            KAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV
Rv1938|M.tuberculosis_H37Rv         KAYRIKELVGDVVGVLDSYGAEQAFVVGHDWGAPVAWTFAWLHPDRCAGV
MMAR_2866|M.marinum_M               KAYRIKELVGDVLGLVDAYGADKAFVIGHDWGAPVAWTFAWLYPQRCAGV
MUL_2888|M.ulcerans_Agy99           KAYRIKELVGDVLGVVDAYGADKAFVIGHDWGAPVAWTFAWLYPQRCAGV
Mvan_4002|M.vanbaalenii_PYR-1       KAYRIKELVGDIVGVIDAYGVERAVVVGHDWGAPVAWTFAWLHPQRCAGV
TH_2582|M.thermoresistible__bu      EDYSILKLVDDCVAIVTALGAEEATIVGHDWGSMVAWTAAWTRPEVFTAV
MAV_0539|M.avium_104                EAYDIHQLTADLVGLLDDVGAQRAVWVGHDWGAAVVWNAPLLHPDRVAAV
MSMEG_6106|M.smegmatis_MC2_155      DDYDITKLTGDVVGLLDDIGAEHAAVIGHDWGAVVAWNAAQLHPDRVAAV
MAB_0528c|M.abscessus_ATCC_199      DDYNIEALSDDLLGILDDVGAGKATFVGHDWGAVVTWHTALAVPERVSGV
Mflv_1415|M.gilvum_PYR-GCK          GVYNVAELTADVVGLLDDVGAERAALVGHDFGAVVAWGAPLLEPDRFSAV
MLBr_02297|M.leprae_Br4923          RGYDGWTLAGDTAGLIRALGHSSATLVGHAEGGLACWATALLHPRLVRAI
                                      *    *  *  .::   *   *  :**  *. . *  .   *    .:

Mb1973|M.bovis_AF2122/97            VGISVPFAGRGVIGLPGSP-FGERRPSDYHLELAGPGRVWYQDYFAVQDG
Rv1938|M.tuberculosis_H37Rv         VGISVPFAGRGVIGLPGSP-FGERRPSDYHLELAGPGRVWYQDYFAVQDG
MMAR_2866|M.marinum_M               VGISVPFAGRGVIGLPGSP-FGEHRPNDYHLELAGEGRVWYQDYFSAQDG
MUL_2888|M.ulcerans_Agy99           VGISVPFAGRGVIGLPGSP-FGEHRPNDYHLELAGEGRVWYQD-FSAQDG
Mvan_4002|M.vanbaalenii_PYR-1       AGISVPFAGRGVIGLPGSP-FGEHRPDDYHLELAGPGRVWYQDYFSAQDG
TH_2582|M.thermoresistible__bu      IGMSVAFGGRGLIPIAGVDSFGTRRPSEVQREIAGPDKVFYQEYWVQKGA
MAV_0539|M.avium_104                AAMSVPVTPR-----------PRLAPTQAWRKMFGEN-FFYILYFQEPGV
MSMEG_6106|M.smegmatis_MC2_155      GGLSVPPTPR-----------STRPPTQAFRELVGEGKFFYILHFQEPGV
MAB_0528c|M.abscessus_ATCC_199      VGLSVPFTRR-----------SQVPPTQAWNKLFGDN-FFYILYFQEPGV
Mflv_1415|M.gilvum_PYR-GCK          AGLSLPPVPR-----------PQVPTTQAFRRVFGDR-FMYILYFQEPGP
MLBr_02297|M.leprae_Br4923          ALINSPHPAA-------------LRRSMLTHRNQGYALLPTLLRYQLPIW
                                      :. .                         .  *   .     :     

Mb1973|M.bovis_AF2122/97            IITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRA
Rv1938|M.tuberculosis_H37Rv         IITEIEEDLRGWLLGLTYTVSGEGMMAATKAAVDAGVDLESMDPIDVIRA
MMAR_2866|M.marinum_M               IIAEIEEDVRTWLLGLTYTVSGDGMIAATKAAADAGVDLASMDPIDVIRA
MUL_2888|M.ulcerans_Agy99           IIAEIEEDVRTWLLGLTYTVSGDGMIAATKAAADAGVDLASMDPIDVIRA
Mvan_4002|M.vanbaalenii_PYR-1       IIAEIEEDLRGWLWGLTYTVSGDGMIAATKAAVAAGVDLESMDPIDVIRA
TH_2582|M.thermoresistible__bu      LESEFEADPRGFLRDQYYSFS-AGPFPPDYQAPNP-LEADPAEVAEQTRS
MAV_0539|M.avium_104                ADAELNADPAQVMRRMMGSLRTDGDKAAGLRMVA----------------
MSMEG_6106|M.smegmatis_MC2_155      ADAEFDGDPARALRRMFGGLLPPENEEAAMRMLR----------------
MAB_0528c|M.abscessus_ATCC_199      ADADLNRDPATTMRRMMAGMAR----IDGATMIA----------------
Mflv_1415|M.gilvum_PYR-GCK          ADAELARDPATTFRRLFALTTG------GAEMVGD---------------
MLBr_02297|M.leprae_Br4923          PERLLTRNNAAEIERLVRSRSS----------------------------
                                        :  :    :                                     

Mb1973|M.bovis_AF2122/97            GPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYH
Rv1938|M.tuberculosis_H37Rv         GPLCMAEGARLKDAFVYPETMPAWFTEADLDFYTGEFERSGFGGPLSFYH
MMAR_2866|M.marinum_M               GPLCMADGARLKDAFVYPETMPAWFTDADLDFYTGEFERSGFGGPLSFYH
MUL_2888|M.ulcerans_Agy99           GPLCMADGARLKDAFVYPETMPAWFTDADLDFYTGEFERSGFGGPLSFYH
Mvan_4002|M.vanbaalenii_PYR-1       GPLCMAEGARLKDAFSYPETMPDWFTEDDLDFYTAEFERSGFGGPLSFYH
TH_2582|M.thermoresistible__bu      GGACLDPGAKMRDGLLTPDPVPDWL-AADLDEYVAEFERTGLEAPLNWYR
MAV_0539|M.avium_104                -----PGPEGFLERLPEPDGLPEWISQDELDHYIAEFSRTGFTGGLNWYR
MSMEG_6106|M.smegmatis_MC2_155      -----PGPEGLIDRLPEPSALPDWISTGEFDHYVDAFTRTGFTGGLNWYR
MAB_0528c|M.abscessus_ATCC_199      -----PGPAGFVERMPDPGELPEWLSQDELDHYITEFARTGFTGGLNWYR
Mflv_1415|M.gilvum_PYR-GCK          -----AGPQGFLDRIPEPGGLPDWISQADFDVYVDEFTRGGFTGPLNWYR
MLBr_02297|M.leprae_Br4923          -----AKWQACEDFAVTIDHLRIAIQIPAAAHCALEYQRWAVR------S
                                                :       :   :           : * ..        

Mb1973|M.bovis_AF2122/97            NIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPNYR
Rv1938|M.tuberculosis_H37Rv         NIDNDWHDLADQQGKPLTPPALFIGGQYDVGTIWGAQAIERAHEVMPNYR
MMAR_2866|M.marinum_M               NIDNDWHDLADQEGKPLSAPALFIGGQYDVGTTWGAEAIARAHEVMSDYR
MUL_2888|M.ulcerans_Agy99           NIDNDWHDLADQEGKPLSAPALFIGGQYDVGTTWGAEAIARAHEVMSDYR
Mvan_4002|M.vanbaalenii_PYR-1       NIDNDWHDLAEQAGTPLTPPAVFIGGQYDVGTTWGAEALERAPEVMPNYC
TH_2582|M.thermoresistible__bu      AMDLSWEELEPYADRPIEVPALFIGADLDVATQWSVEAVAAFDRTVPKHR
MAV_0539|M.avium_104                NFDRNWETTPELDGAKIAVPCLFIGGTADP--VLSFTRADRAAEVISGPY
MSMEG_6106|M.smegmatis_MC2_155      NFDRNWELTAHLADAKITVPALFLAGAADP--VLGFARPDRARDLIAGPY
MAB_0528c|M.abscessus_ATCC_199      NFDRNWALTERLAGANVVVPSLFIAGAADP--VLGFTDHAGSAKYRTDNR
Mflv_1415|M.gilvum_PYR-GCK          CFDRNWELTAETPAPTIEVPALFVGGTEDA--TLAYTPRDRVREVVTGDY
MLBr_02297|M.leprae_Br4923          QLRNEGRKFMKSMSRPFSVPLLHVRGDADP--YLLADSVDRTRRYAPHG-
                                     :  .           .  * :.: .  *                 .   

Mb1973|M.bovis_AF2122/97            GTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP----
Rv1938|M.tuberculosis_H37Rv         GTHMIADVGHWIQQEAPEETNRLLLDFLGGLRP----
MMAR_2866|M.marinum_M               GTHMVADVGHWIQQEAPDETNRLLLEFLGGLRQ----
MUL_2888|M.ulcerans_Agy99           GTHMVADVGHWIQQEAPDETNRLLLEFLGGLRQ----
Mvan_4002|M.vanbaalenii_PYR-1       GTHMVPDVGHWIQQEAPEETNRLLLDFLRGLG-----
TH_2582|M.thermoresistible__bu      PSVILQNCGHWFTRERPAETTAAILEFLEGLGHGR--
MAV_0539|M.avium_104                RHVMIDGAGHWLQQERPAEVNAALLDFLNGLELR---
MSMEG_6106|M.smegmatis_MC2_155      TEILLDGAGHWVQQERAEEVNAALIGFLHGLELQ---
MAB_0528c|M.abscessus_ATCC_199      GDLLIDGAGHWIQQERPLEVNAALLAFLREVVH----
Mflv_1415|M.gilvum_PYR-GCK          REVMIDGAGHWLTEERPDEVSRVLVDFLTTVR-----
MLBr_02297|M.leprae_Br4923          RYVSVSDAGHFSHEEAPEEINRYLTRFLKQVHGPRLS
                                        : . **:  .* . * .  :  **  :