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M. thermoresistible (build 8) TH_2372 ()

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 4642556 - 4643578
length: 341

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2372 - 100% (341) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. thermoresistible (build 8) TH_2371 - 2e-97 56.42% (335) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2742 - 1e-85 50.60% (334) integral membrane protein
M. gilvum PYR-GCK Mflv_1405 - 1e-96 54.63% (324) integral membrane protein TerC
M. tuberculosis H37Rv Rv2723 - 1e-85 50.60% (334) integral membrane protein
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_0511c - 1e-102 57.45% (322) integral membrane protein TerC (tellurium resistance)
M. marinum M MMAR_1990 - 3e-82 47.45% (333) hypothetical protein MMAR_1990
M. avium 104 - - - - -
M. smegmatis MC2 155 MSMEG_6136 - 1e-103 56.84% (329) membrane protein, TerC family protein
M. ulcerans Agy99 - - - - -
M. vanbaalenii PYR-1 Mvan_5385 - 1e-99 56.70% (321) integral membrane protein TerC

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1405|M.gilvum_PYR-GCK          MNVSGLEWGITLAVTIGILLFDVLVIGRRPHEPSKRETGTALTIYIALAI
Mvan_5385|M.vanbaalenii_PYR-1       MNVSGLEWAITLTVTLAILLFDVIVIGRRPHEPSRRETATALTFYVGLAI
MSMEG_6136|M.smegmatis_MC2_155      MHVTQLEWIITLSVTIAVLLFDVVIIGRRPHEPTRRETATYLSIYIGLAI
MAB_0511c|M.abscessus_ATCC_199      MQVSQLEWIITLAVTVAILLVDVIVIGRQPHEPSTRETATALSIYVGLAV
TH_2372|M.thermoresistible__bu      VNVTATVWAITIGVILALFAFDLIFHARKPHAPSFRESAVWSAGYVTLAL
Mb2742|M.bovis_AF2122/97            MGASGLVWTLTIVLIAGLMLVDYVLHVRKTHVPTLRQAVIQSATFVGIAI
Rv2723|M.tuberculosis_H37Rv         MGASGLVWTLTIVLIAGLMLVDYVLHVRKTHVPTLRQAVIQSATFVGIAI
MMAR_1990|M.marinum_M               MGVPTIVWALTIVMVAALMLFDYVFHVRHTHVPTLREAALWSAIYIGVAI
                                    : ..   * :*: :  .:: .* :.  *:.* *: *::    : :: :*:

Mflv_1405|M.gilvum_PYR-GCK          AFGVWTWTFHGSEYGVEFFAGWLTEYSLSVDNLFIFLIIMASFKVPRIYQ
Mvan_5385|M.vanbaalenii_PYR-1       AFGLWTWFFHGSQYGLEFFAGWLTEYSLSVDNLFIFLIIMASFKVPRIYQ
MSMEG_6136|M.smegmatis_MC2_155      AFGVWTWLFHGHRYGVEFFAGWLTEYSLSVDNLFIFLIIMASFKVPRIYQ
MAB_0511c|M.abscessus_ATCC_199      AFGLWVWFFHGSQYGLEFYAGWLTEYSLSVDNLFIFLIIMASFKVPRVYQ
TH_2372|M.thermoresistible__bu      VFGLIVLWLWGIDYAGEYYAGFVTEWALSVDNLFVFTIIMSSFAVPREHQ
Mb2742|M.bovis_AF2122/97            LFGIAVVVFGGSELAVEYFACYLTDEALSVDNLFVFLVIISSFGVPRLAQ
Rv2723|M.tuberculosis_H37Rv         LFGIAVVVFGGSELAVEYFACYLTDEALSVDNLFVFLVIISSFGVPRLAQ
MMAR_1990|M.marinum_M               LFGVGVVIFGSIGMGIEYFAGYLSNEALSVDNLFVFLVVISSFGVPRVAQ
                                     **: .  : .   . *::* :::: :*******:* ::::** ***  *

Mflv_1405|M.gilvum_PYR-GCK          QQALLVGIILALIFRGIFIALGAVAIEQFSWVFYLFGAFLLYTAIKLVKD
Mvan_5385|M.vanbaalenii_PYR-1       QQALLVGIILALIFRGIFIALGAVAIQQFSWVFYIFGAFLLYTAVKLVKD
MSMEG_6136|M.smegmatis_MC2_155      QQALLVGIILALIFRGIFIALGAVAINQFSWVFYIFGAFLVYTAVNLVRD
MAB_0511c|M.abscessus_ATCC_199      QEALLVGIILALIFRGIFIALGAVAINQFSWIFYLFGAFLVYTAINLARD
TH_2372|M.thermoresistible__bu      PKVLLIGILMALGMRGIFIALGAAAINTFSWVFYLFGLFLVWTAVGLLRE
Mb2742|M.bovis_AF2122/97            QKVLLFGIAFALVTRTGFIFVGAALIENFNSAFYLFGLVLLVMAGNLARP
Rv2723|M.tuberculosis_H37Rv         QKVLLFGIAFALVTRTGFIFVGAALIENFNSAFYLFGLVLLVMAGNLARP
MMAR_1990|M.marinum_M               QKVLLFGVAFALIARTGFILLGGALIEHFNAAFYVFGLTLLIMAGNLAKP
                                     :.**.*: :**  *  ** :*.. *: *.  **:**  *:  *  * : 

Mflv_1405|M.gilvum_PYR-GCK          TDHDD-DGD----NAVVRFAQKRMKFTDTWDGLRLWVHENGQRLMTPMFL
Mvan_5385|M.vanbaalenii_PYR-1       TDHDD-DAD----NAVVRFAQKRMKFTDQWDGLRLWVTENGQRLMTPMFL
MSMEG_6136|M.smegmatis_MC2_155      TDHDD-DGD----NAVVRFARKHLRTTDKWDGLRLWVRENGKRLITPMFL
MAB_0511c|M.abscessus_ATCC_199      TEHDD-DAD----NAVVQFARKHLRTTDKWDGLRLWVRENGTRLMTPMFL
TH_2372|M.thermoresistible__bu      GGHEQ-EVEEQRENRIVRTVRRFVPTTRQYHGAKLSVRIDGKRVVTPMLL
Mb2742|M.bovis_AF2122/97            TGLESRDAETLKRSVIIRLADRFLRTSQDYNGDRLFTVSNNKRMMTPLLL
Rv2723|M.tuberculosis_H37Rv         TGLESRDAETLKRSVIIRLADRFLRTSQDYNGDRLFTVSNNKRMMTPLLL
MMAR_1990|M.marinum_M               AAAESRDADNLA----IRLANRFLRTSQNYNGDRFFIVENEGRVMTPLLL
                                       :. : :       :: . : :  :  :.* ::    :  *::**::*

Mflv_1405|M.gilvum_PYR-GCK          VIVALGTTDLLFALDSIPAIYGLTQEPYLVFTANVFALMGLRQLYFLLGD
Mvan_5385|M.vanbaalenii_PYR-1       VIVALGTTDLIFALDSIPAIYGLTREPYLVFTANVFALMGLRQLYFLLGD
MSMEG_6136|M.smegmatis_MC2_155      VIVALGTTDLLFALDSIPAIYGLTQEPYLVFTANVFALMGLRQLYFLLGD
MAB_0511c|M.abscessus_ATCC_199      VIVALGTTDLLFALDSIPAIYGLTKEPYLVFTANVFALMGLRQLYFLLGD
TH_2372|M.thermoresistible__bu      ALITIGFTDILFALDSIPAIFGLTREPYIVFTANAFALMGLRQLYFLIGG
Mb2742|M.bovis_AF2122/97            VMIAVGGTDILFAFDSIPALFGLTQNVYLVFAATAFSLLGLRQLYFLIDG
Rv2723|M.tuberculosis_H37Rv         VMIAVGGTDILFAFDSIPALFGLTQNVYLVFAATAFSLLGLRQLYFLIDG
MMAR_1990|M.marinum_M               VMLAVGGSDVLFAFDSVPALFGLTQNVYLLFAATAFSLLGLRQLYFLIDN
                                    .::::* :*::**:**:**::***:: *::*:*..*:*:********:..

Mflv_1405|M.gilvum_PYR-GCK          LLKRLVYLSQGLAFILFFIGVKLVLHALHENEVPFINGGENVPVPEIPTL
Mvan_5385|M.vanbaalenii_PYR-1       LLKRLVYLSQGLAFILFFIGVKLVLHALHENELPFINGGEHVPVPEIPTL
MSMEG_6136|M.smegmatis_MC2_155      LLKRLVYLSQGLAFILAFIGVKLILHALHENELPFINGGEPVHVPEIPTL
MAB_0511c|M.abscessus_ATCC_199      MLKRLVYLSQGLAFILFFIGVKLILHALHENELPFINGGEPVHVPEIPTL
TH_2372|M.thermoresistible__bu      LLDRLVFLSYGLSLILAFIGVKLVLHALHENELPFVNDGQPVAVPEVSTG
Mb2742|M.bovis_AF2122/97            LLDRLVYLSYGLAVILGFIGVKLMLEALHDNKIPFINGGKPVPTVEVSTT
Rv2723|M.tuberculosis_H37Rv         LLDRLVYLSYGLAVILGFIGVKLMLEALHDNKIPFINGGKPVPTVEVSTT
MMAR_1990|M.marinum_M               LLYRLIYLPYGLATILGFIGIKLMLEALHHNTIAFINRGRPVTTVEMSTA
                                    :* **::*. **: ** ***:**:*.***.* :.*:* *. * . *:.* 

Mflv_1405|M.gilvum_PYR-GCK          LSLGVIIVTLLITTVASLYKTRVHDVRKNGTSEGSEGPDAVDDTETPHGD
Mvan_5385|M.vanbaalenii_PYR-1       LSLGVIVVTLILTTIASLYKTRVHDVRKNGAS-------TEKTEADPHPD
MSMEG_6136|M.smegmatis_MC2_155      ASLGVIVVTLLITTAASLYKTRVRDAQ-----------------------
MAB_0511c|M.abscessus_ATCC_199      ASLAVIVVTLLVTTVASLYKTRRTAP------------------------
TH_2372|M.thermoresistible__bu      VSLAFIGTVLVITTVASLLKTRRDEKQ------------AKKANRIPEVR
Mb2742|M.bovis_AF2122/97            QSLTVIIIVLLITTAASFWSARGRAQNAMARARRYATAYLDLHYETESAE
Rv2723|M.tuberculosis_H37Rv         QSLTVIIIVLLITTAASFWSARGRAQNAMARARRYATAYLDLHYETESAE
MMAR_1990|M.marinum_M               MSLTVIVVVLLLTTVASLVSVRGRRENAAARARRHALEYLDLHHPADPVE
                                     ** .*  .*::** **: ..*                            

Mflv_1405|M.gilvum_PYR-GCK          RAR--------------------------------------------
Mvan_5385|M.vanbaalenii_PYR-1       PSR--------------------------------------------
MSMEG_6136|M.smegmatis_MC2_155      -----------------------------------------------
MAB_0511c|M.abscessus_ATCC_199      -----------------------------------------------
TH_2372|M.thermoresistible__bu      EVS--------------------------------------------
Mb2742|M.bovis_AF2122/97            RDKIFTALLAAERQINTLPTKYRMQPGQDDDLMTLLCRAHAARDAHM
Rv2723|M.tuberculosis_H37Rv         RDKIFTALLAAERQINTLPTKYRMQPGQDDDLMTLLCRAHAARDAHM
MMAR_1990|M.marinum_M               REGIFAALLQAEDEISSLPLKHRAQVQQDTELTTLLQQAHNAREARE

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2372		-	100% (341)	PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. thermoresistible (build 8)	TH_2371	-	2e-97	56.42% (335)	PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN