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M. thermoresistible (build 8) TH_2371 ()

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 4640880 - 4642088
length: 403

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2371-100% (403)PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. thermoresistible (build 8)TH_2372-2e-9756.42% (335) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2742-1e-12458.12% (394) integral membrane protein
M. gilvum PYR-GCKMflv_1405-2e-8954.26% (317) integral membrane protein TerC
M. tuberculosis H37RvRv2723-1e-12458.12% (394) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0511c-2e-9255.00% (320) integral membrane protein TerC (tellurium resistance)
M. marinum MMMAR_1990-1e-12558.61% (389) hypothetical protein MMAR_1990
M. avium 104-----
M. smegmatis MC2 155MSMEG_6136-2e-9455.84% (317) membrane protein, TerC family protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5385-9e-9255.21% (317) integral membrane protein TerC

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1405|M.gilvum_PYR-GCK          MNVSGLEWGITLAVTIGILLFDVLVIGRRPHEPSKRETGTALTIYIALAI
Mvan_5385|M.vanbaalenii_PYR-1       MNVSGLEWAITLTVTLAILLFDVIVIGRRPHEPSRRETATALTFYVGLAI
MSMEG_6136|M.smegmatis_MC2_155      MHVTQLEWIITLSVTIAVLLFDVVIIGRRPHEPTRRETATYLSIYIGLAI
MAB_0511c|M.abscessus_ATCC_199      MQVSQLEWIITLAVTVAILLVDVIVIGRQPHEPSTRETATALSIYVGLAV
Mb2742|M.bovis_AF2122/97            MGASGLVWTLTIVLIAGLMLVDYVLHVRKTHVPTLRQAVIQSATFVGIAI
Rv2723|M.tuberculosis_H37Rv         MGASGLVWTLTIVLIAGLMLVDYVLHVRKTHVPTLRQAVIQSATFVGIAI
MMAR_1990|M.marinum_M               MGVPTIVWALTIVMVAALMLFDYVFHVRHTHVPTLREAALWSAIYIGVAI
TH_2371|M.thermoresistible__bu      MVVPPLIWALTIALIAALVAFDFFFHVRKAHIPTLPEAAKWSAFYVGLAV
                                    * .. : * :*: :  .:: .* ..  *:.* *:  ::    : ::.:*:

Mflv_1405|M.gilvum_PYR-GCK          AFGVWTWTFHGSEYGVEFFAGWLTEYSLSVDNLFIFLIIMASFKVPRIYQ
Mvan_5385|M.vanbaalenii_PYR-1       AFGLWTWFFHGSQYGLEFFAGWLTEYSLSVDNLFIFLIIMASFKVPRIYQ
MSMEG_6136|M.smegmatis_MC2_155      AFGVWTWLFHGHRYGVEFFAGWLTEYSLSVDNLFIFLIIMASFKVPRIYQ
MAB_0511c|M.abscessus_ATCC_199      AFGLWVWFFHGSQYGLEFYAGWLTEYSLSVDNLFIFLIIMASFKVPRVYQ
Mb2742|M.bovis_AF2122/97            LFGIAVVVFGGSELAVEYFACYLTDEALSVDNLFVFLVIISSFGVPRLAQ
Rv2723|M.tuberculosis_H37Rv         LFGIAVVVFGGSELAVEYFACYLTDEALSVDNLFVFLVIISSFGVPRLAQ
MMAR_1990|M.marinum_M               LFGVGVVIFGSIGMGIEYFAGYLSNEALSVDNLFVFLVVISSFGVPRVAQ
TH_2371|M.thermoresistible__bu      LFGVGVTIFGGTDPGLEYFAGWITEKALSVDNLFVFLVIIASFKVPRADQ
                                     **: .  * .   .:*::* :::: :*******:**::::** ***  *

Mflv_1405|M.gilvum_PYR-GCK          QQALLVGIILALIFRGIFIALGAVAIEQFSWVFYLFGAFLLYTAIKLVKD
Mvan_5385|M.vanbaalenii_PYR-1       QQALLVGIILALIFRGIFIALGAVAIQQFSWVFYIFGAFLLYTAVKLVKD
MSMEG_6136|M.smegmatis_MC2_155      QQALLVGIILALIFRGIFIALGAVAINQFSWVFYIFGAFLVYTAVNLVRD
MAB_0511c|M.abscessus_ATCC_199      QEALLVGIILALIFRGIFIALGAVAINQFSWIFYLFGAFLVYTAINLARD
Mb2742|M.bovis_AF2122/97            QKVLLFGIAFALVTRTGFIFVGAALIENFNSAFYLFGLVLLVMAGNLARP
Rv2723|M.tuberculosis_H37Rv         QKVLLFGIAFALVTRTGFIFVGAALIENFNSAFYLFGLVLLVMAGNLARP
MMAR_1990|M.marinum_M               QKVLLFGVAFALIARTGFILLGGALIEHFNAAFYVFGLTLLIMAGNLAKP
TH_2371|M.thermoresistible__bu      QKVLLFGIVFALIARTGMIFLGAALINAFAWVFYVFGFILVMTAGQLLVP
                                    *:.**.*: :**: *  :* :*.. *: *   **:**  *:  * :*   

Mflv_1405|M.gilvum_PYR-GCK          T-DHDDDGDNAV----VRFAQKRMKFTDTWDGLRLWVHENGQRLMTPMFL
Mvan_5385|M.vanbaalenii_PYR-1       T-DHDDDADNAV----VRFAQKRMKFTDQWDGLRLWVTENGQRLMTPMFL
MSMEG_6136|M.smegmatis_MC2_155      T-DHDDDGDNAV----VRFARKHLRTTDKWDGLRLWVRENGKRLITPMFL
MAB_0511c|M.abscessus_ATCC_199      T-EHDDDADNAV----VQFARKHLRTTDKWDGLRLWVRENGTRLMTPMFL
Mb2742|M.bovis_AF2122/97            TGLESRDAETLKRSVIIRLADRFLRTSQDYNGDRLFTVSNNKRMMTPLLL
Rv2723|M.tuberculosis_H37Rv         TGLESRDAETLKRSVIIRLADRFLRTSQDYNGDRLFTVSNNKRMMTPLLL
MMAR_1990|M.marinum_M               AAAESRDADNLA----IRLANRFLRTSQNYNGDRFFIVENEGRVMTPLLL
TH_2371|M.thermoresistible__bu      S-DEDRTADNVV----IRLAKRFFPTTSEYDEDKIVTVRDGKRVLTPMLL
                                    :  ..  .:.      :::* : :  :. ::  ::    :  *::**::*

Mflv_1405|M.gilvum_PYR-GCK          VIVALGTTDLLFALDSIPAIYGLTQEPYLVFTANVFALMGLRQLYFLLGD
Mvan_5385|M.vanbaalenii_PYR-1       VIVALGTTDLIFALDSIPAIYGLTREPYLVFTANVFALMGLRQLYFLLGD
MSMEG_6136|M.smegmatis_MC2_155      VIVALGTTDLLFALDSIPAIYGLTQEPYLVFTANVFALMGLRQLYFLLGD
MAB_0511c|M.abscessus_ATCC_199      VIVALGTTDLLFALDSIPAIYGLTKEPYLVFTANVFALMGLRQLYFLLGD
Mb2742|M.bovis_AF2122/97            VMIAVGGTDILFAFDSIPALFGLTQNVYLVFAATAFSLLGLRQLYFLIDG
Rv2723|M.tuberculosis_H37Rv         VMIAVGGTDILFAFDSIPALFGLTQNVYLVFAATAFSLLGLRQLYFLIDG
MMAR_1990|M.marinum_M               VMLAVGGSDVLFAFDSVPALFGLTQNVYLLFAATAFSLLGLRQLYFLIDN
TH_2371|M.thermoresistible__bu      VMVAIGGTDLMFALDSIPAIFGLTQNVYIVFTATAFSLLGLRQLYFLIDG
                                    *::*:* :*::**:**:**::***:: *::*:*..*:*:********:..

Mflv_1405|M.gilvum_PYR-GCK          LLKRLVYLSQGLAFILFFIGVKLVLHALHENEVPFINGGENVPVPEIPTL
Mvan_5385|M.vanbaalenii_PYR-1       LLKRLVYLSQGLAFILFFIGVKLVLHALHENELPFINGGEHVPVPEIPTL
MSMEG_6136|M.smegmatis_MC2_155      LLKRLVYLSQGLAFILAFIGVKLILHALHENELPFINGGEPVHVPEIPTL
MAB_0511c|M.abscessus_ATCC_199      MLKRLVYLSQGLAFILFFIGVKLILHALHENELPFINGGEPVHVPEIPTL
Mb2742|M.bovis_AF2122/97            LLDRLVYLSYGLAVILGFIGVKLMLEALHDNKIPFINGGKPVPTVEVSTT
Rv2723|M.tuberculosis_H37Rv         LLDRLVYLSYGLAVILGFIGVKLMLEALHDNKIPFINGGKPVPTVEVSTT
MMAR_1990|M.marinum_M               LLYRLIYLPYGLATILGFIGIKLMLEALHHNTIAFINRGRPVTTVEMSTA
TH_2371|M.thermoresistible__bu      LLDRLVYLHFGLAFILGFIGVKLFLHALHENNVPFINDGEPVNVVEVSTP
                                    :* **:**  *** ** ***:**.*.***.* :.*** *. * . *:.* 

Mflv_1405|M.gilvum_PYR-GCK          LSLGVIIVTLLITTVASLYKTR------VHDVRKNGTSEGSEGPDAVDDT
Mvan_5385|M.vanbaalenii_PYR-1       LSLGVIVVTLILTTIASLYKTR------VHDVRKNGAS-------TEKTE
MSMEG_6136|M.smegmatis_MC2_155      ASLGVIVVTLLITTAASLYKTR------VRDAQ-----------------
MAB_0511c|M.abscessus_ATCC_199      ASLAVIVVTLLVTTVASLYKTR------RTAP------------------
Mb2742|M.bovis_AF2122/97            QSLTVIIIVLLITTAASFWSARGRAQNAMARARRYATAYLDLHYET-ESA
Rv2723|M.tuberculosis_H37Rv         QSLTVIIIVLLITTAASFWSARGRAQNAMARARRYATAYLDLHYET-ESA
MMAR_1990|M.marinum_M               MSLTVIVVVLLLTTVASLVSVRGRRENAAARARRHALEYLDLHHPA-DPV
TH_2371|M.thermoresistible__bu      LSLVVILATLTVTTVASLVSPRGKARNSVAKVRRYATAYLDEAYYGGFTE
                                     ** **: .* :** **: . *                            

Mflv_1405|M.gilvum_PYR-GCK          ET-----------------PHGDRAR------------------------
Mvan_5385|M.vanbaalenii_PYR-1       AD-----------------PHPDPSR------------------------
MSMEG_6136|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0511c|M.abscessus_ATCC_199      --------------------------------------------------
Mb2742|M.bovis_AF2122/97            ERDKIFTALLAAERQINTLPTKYRMQPGQDD-DLMTLLCRAHAARDAHM-
Rv2723|M.tuberculosis_H37Rv         ERDKIFTALLAAERQINTLPTKYRMQPGQDD-DLMTLLCRAHAARDAHM-
MMAR_1990|M.marinum_M               EREGIFAALLQAEDEISSLPLKHRAQVQQDT-ELTTLLQQAHNAREARE-
TH_2371|M.thermoresistible__bu      ERAKAFEELCREEQKIAALPAKHRAMIVRDEAELLDLIRRAHDEHNRYLA
                                                                                      

Mflv_1405|M.gilvum_PYR-GCK          -------
Mvan_5385|M.vanbaalenii_PYR-1       -------
MSMEG_6136|M.smegmatis_MC2_155      -------
MAB_0511c|M.abscessus_ATCC_199      -------
Mb2742|M.bovis_AF2122/97            -------
Rv2723|M.tuberculosis_H37Rv         -------
MMAR_1990|M.marinum_M               -------
TH_2371|M.thermoresistible__bu      DEQQQQQ