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M. thermoresistible (build 8) TH_2314 (thiG)

annotation: PROBABLE THIAMIN BIOSYNTHESIS PROTEIN THIG (THIAZOLE BIOSYNTHESIS PROTEIN)
coordinates: 4534082 - 4534849
length: 256

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2314 thiG - 100% (256) PROBABLE THIAMIN BIOSYNTHESIS PROTEIN THIG (THIAZOLE BIOSYNTHESIS PROTEIN)
M. thermoresistible (build 8) TH_2055 - 5e-05 35.38% (65) Possible pyridoxine biosynthesis protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0425 thiG 1e-118 86.18% (246) thiazole synthase
M. gilvum PYR-GCK Mflv_0195 thiG 1e-119 87.10% (248) thiazole synthase
M. tuberculosis H37Rv Rv0417 thiG 1e-116 85.77% (246) thiazole synthase
M. leprae Br4923 MLBr_00297 thiG 1e-114 83.06% (248) thiazole synthase
M. abscessus ATCC 19977 MAB_4216c thiG 1e-118 87.04% (247) thiazole synthase
M. marinum M MMAR_0720 thiG 1e-120 87.50% (248) thiamin biosynthesis protein ThiG
M. avium 104 MAV_4744 thiG 1e-122 88.66% (247) thiazole synthase
M. smegmatis MC2 155 MSMEG_0793 thiG 1e-120 88.66% (247) thiazole synthase
M. ulcerans Agy99 MUL_2803 thiG 1e-119 86.69% (248) thiazole synthase
M. vanbaalenii PYR-1 Mvan_0710 thiG 1e-121 88.40% (250) thiazole synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0425|M.bovis_AF2122/97            --------------MAESKLVIGDRSFASRLIMGTGGATNLAVLEQALIA
Rv0417|M.tuberculosis_H37Rv         --------------MAESKLVIGDRSFASRLIMGTGGATNLAVLEQALIA
Mflv_0195|M.gilvum_PYR-GCK          MVE----------FGTGK-LSIAGREFGSRLILGTGGAANLAVLEAALVA
Mvan_0710|M.vanbaalenii_PYR-1       MAESEVSDFADSDFATGK-LSIAGREFGSRLILGTGGAANLAVLEAALVA
TH_2314|M.thermoresistible__bu      VAS----------PDTDK-LTIAGRTFGSRLILGTGGAANLAILEEALVA
MAB_4216c|M.abscessus_ATCC_199      -------------MGTGESLCIAGRTFGSRLIMGTGGAANLSILERALVA
MSMEG_0793|M.smegmatis_MC2_155      --------------MADSVLRIGGREFGSRLIMGTGGAPNLSVLEEALIA
MMAR_0720|M.marinum_M               --------------MVESKLTIADRSFASRLIMGTGGASNLAVLQEALVA
MUL_2803|M.ulcerans_Agy99           --------------MVESKLMIADRSFASRLIMGTGGASNLAVLQEALVA
MAV_4744|M.avium_104                --------------MVDSKLTIADRSFSSRLIMGTGGAGNLAVLEEALIA
MLBr_00297|M.leprae_Br4923          --------------MVESKFTIGDRTFTSRLIMGTGGAANLAILEEALIA
                                                   . . : *..* * ****:***** **::*: **:*

Mb0425|M.bovis_AF2122/97            SGTELTTVAIRRVDADGGTGLLDLLNRLGITPLPNTAGCRSAAEAVLTAQ
Rv0417|M.tuberculosis_H37Rv         SGTELTTVAIRRVDADGGTGLLDLLNRLGITPLPNTAGSRSAAEAVLTAQ
Mflv_0195|M.gilvum_PYR-GCK          SGTELTTVAMRRIDADGGTGVLDLLTRLGITPLPNTAGCRGAAEAVMTAQ
Mvan_0710|M.vanbaalenii_PYR-1       SGTELTTVAMRRVDAEGGTGVLDLLTRLGISPLPNTAGCRGAAEAVMTAQ
TH_2314|M.thermoresistible__bu      SGTELTTVAMRRVDAEGGTGVLELLNRLGITPLPNTAGCRGAAEAVYTAQ
MAB_4216c|M.abscessus_ATCC_199      SGTELTTVAIRRVDAAGGTGVLDLLKRLDIVPLPNTAGCRGAAEAVMTAR
MSMEG_0793|M.smegmatis_MC2_155      SGTELTTVAMRRVDAETGTGVLDLLNRLGIAALPNTAGCRGAAEAVLTAQ
MMAR_0720|M.marinum_M               SGTELTTVAIRRVDAEGGTGLLDLLNRLGITPLPNTAGCRSAAEAVLTAQ
MUL_2803|M.ulcerans_Agy99           SGTELTTVAIRRVDAEGGTGLLDLLNRLGITPLPNTAGCRSAAEAVLTAQ
MAV_4744|M.avium_104                SGTELTTVAIRRVDAEGGTGLLDLLNRLGITPLPNTAGCRGAAEAVLTAQ
MLBr_00297|M.leprae_Br4923          SGTELTTVAIRRVDTDGGSGLLKLLSRLDIMPLPNTAGCRSAAEAVLTAQ
                                    *********:**:*:  *:*:*.**.**.* .******.*.***** **:

Mb0425|M.bovis_AF2122/97            LAREALNTNWVKLEVIADERTLWPDAVELVRAAEQLVDDGFVVLPYTTDD
Rv0417|M.tuberculosis_H37Rv         LAREALNTNWVKLEVIADERTLWPDAVELVRAAEQLVDDGFVVLPYTTDD
Mflv_0195|M.gilvum_PYR-GCK          LAREALQTNWVKLEVIADERTLLPDAVELVRAAEQLVDDGFAVLPYTNDD
Mvan_0710|M.vanbaalenii_PYR-1       LAREALQTNWVKLEVIADERTLLPDAIELVRAAEQLVDDGFVVLPYTNDD
TH_2314|M.thermoresistible__bu      LGREALDTDWVKLEVIADERTLLPDAVELVRAAEQLVDDGFTVLPYTNDD
MAB_4216c|M.abscessus_ATCC_199      LAREALETDWIKLEVIADERTLLPDAVELVRAAEQLVDDGFVVLPYTTDD
MSMEG_0793|M.smegmatis_MC2_155      LAREALGTDMVKLEVIADERTLLPDAVELVKAAEQLVDDGFTVLPYTNDD
MMAR_0720|M.marinum_M               LAREALATNWVKLEVIADERTLLPDAIELVRAAEQLVDDGFVVLPYTNDD
MUL_2803|M.ulcerans_Agy99           LAREALATNWVKLEVIADERTLLPDAIELVRAAEQLVDDGFVVLPYTNDD
MAV_4744|M.avium_104                LAREALNTNWIKLEVIADERTLLPDAVELVRAAEQLVDDGFVVLPYTNDD
MLBr_00297|M.leprae_Br4923          LAREALNTNWIKLEVIADERTLLPDGLELVRAAEQLVDAGFVVLPYTNDD
                                    *.**** *: :*********** **.:***:******* **.*****.**

Mb0425|M.bovis_AF2122/97            PVLARRLEDTGCAAVMPLGSPIGTGLGIANPHNIEMIVAGARVPVVLDAG
Rv0417|M.tuberculosis_H37Rv         PVLARRLEDTGCAAVMPLGSPIGTGLGIANPHNIEMIVAGARVPVVLDAG
Mflv_0195|M.gilvum_PYR-GCK          PVLARRLEATGCVAVMPLGSPIGTGLGIANPHNIEMIVDSAQVPVILDAG
Mvan_0710|M.vanbaalenii_PYR-1       PVLARRLEATGCAAVMPLGSPIGTGLGIANPHNIEMIVDQASVPVILDAG
TH_2314|M.thermoresistible__bu      PVLAKRLEDVGCAAVMPLGSPIGTGLGISNPHNIEMIVAQSNVPVILDAG
MAB_4216c|M.abscessus_ATCC_199      PVLARRLEDVGCAAVMPLGSPIGTGLGITNTHNIEMIVAAAGVPVILDAG
MSMEG_0793|M.smegmatis_MC2_155      PVLARRLEDIGCAAVMPLGSPIGTGLGISNPHNIEMIVAAAGVPVVLDAG
MMAR_0720|M.marinum_M               PVLARRLEDTGCAAVMPLGSPIGTGLGITNPHNIEMIVASAGVPVVLDAG
MUL_2803|M.ulcerans_Agy99           PVLARRLEDTGCAAVMPLGSPIGTGLGITNPHNIEMIVASAGVPVVLDAG
MAV_4744|M.avium_104                PVLARRLEDAGCAAVMPLGSPIGTGLGITNPHNIEMIVAGAGVPVVLDAG
MLBr_00297|M.leprae_Br4923          PALAHRLEGTGCAAVMPLGSPIGTGLGINNPHNIEIIVAQARVPVVLDAG
                                    *.**:***  **.*************** *.****:**  : ***:****

Mb0425|M.bovis_AF2122/97            IGTASDAALAMELGCDAVLLASAVTRAADPPAMAAAMAAAVTAGYLARCA
Rv0417|M.tuberculosis_H37Rv         IGTASDAALAMELGCDAVLLASAVTRAADPPAMAAAMAAAVTAGYLARCA
Mflv_0195|M.gilvum_PYR-GCK          IGTASDAALAMELGCDAVLLASAVTRAADPAAMAAAMSAAVRAGHLARHA
Mvan_0710|M.vanbaalenii_PYR-1       IGTASDAALAMELGCDAVLLASAVTRSADPPAMAAAMAAAVRAGYLARRA
TH_2314|M.thermoresistible__bu      IGTASDAALAMELGCDAVLLATAVTRAGDPPKMAAAMAAAVTAGRLARQA
MAB_4216c|M.abscessus_ATCC_199      IGTASDAALAMELGCDAVLLATAVTRAADPERMAAAMAAAVNAGHLARHA
MSMEG_0793|M.smegmatis_MC2_155      IGTASDAALAMELGCDAVLLATAVTRASDPPTMAAAMASAVTAGHLARQA
MMAR_0720|M.marinum_M               IGTASDAALAMELGCDAVLLATAVTRAADPAAMAAAMSAAVTAGYLARRA
MUL_2803|M.ulcerans_Agy99           IGTASDAALAMELGCDALLLATAVTRAADPAAMAAAMSAAVTAGYLARCA
MAV_4744|M.avium_104                IGTASDAALAMELGCDAVLLATAVTRAGDPAAMAAAMSAAVTAGYLARRA
MLBr_00297|M.leprae_Br4923          IGTTSDAALAMELGCDAVLLASAVTRAVDPPTMAAAMASAVTAGYLARRA
                                    ***:*************:***:****: **  *****::** ** *** *

Mb0425|M.bovis_AF2122/97            GRIPKRFWAQASSPAR------------
Rv0417|M.tuberculosis_H37Rv         GRIPKRFWAQASSPAR------------
Mflv_0195|M.gilvum_PYR-GCK          GRIPKRFWAHASSPAFE-----------
Mvan_0710|M.vanbaalenii_PYR-1       GRIPKRFWAQASSPSL------------
TH_2314|M.thermoresistible__bu      GRIPKRFWAQASSPPL------------
MAB_4216c|M.abscessus_ATCC_199      GRIPRRFWAQASSPAPDRPLEQ------
MSMEG_0793|M.smegmatis_MC2_155      GRIPKRFWAQASSPAL------------
MMAR_0720|M.marinum_M               GRIPKRFWAQASSPTLVTTQSPGAESGN
MUL_2803|M.ulcerans_Agy99           GRIPKRFWAQASSPTLVTTQSPGAESGN
MAV_4744|M.avium_104                GRIPKRFWAQASSPPR------------
MLBr_00297|M.leprae_Br4923          GRIPKRFWAQASSPELMRTGEELGN---
                                    ****:****:****

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2314	thiG	-	100% (256)	PROBABLE THIAMIN BIOSYNTHESIS PROTEIN THIG (THIAZOLE BIOSYNTHESIS PROTEIN)
M. thermoresistible (build 8)	TH_2055	-	5e-05	35.38% (65)	Possible pyridoxine biosynthesis protein