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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2241 | otsA | - | 100% (487) | PROBABLE ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3520 | otsA | 0.0 | 79.88% (482) | alpha,alpha-trehalose-phosphate synthase |
M. gilvum PYR-GCK | Mflv_1566 | - | 0.0 | 80.63% (475) | Alpha,alpha-trehalose-phosphate synthase (UDP-forming) |
M. tuberculosis H37Rv | Rv3490 | otsA | 0.0 | 79.88% (482) | alpha,alpha-trehalose-phosphate synthase |
M. leprae Br4923 | MLBr_02254 | otsA | 0.0 | 80.00% (480) | putative trehalose-phosphate synthase |
M. abscessus ATCC 19977 | MAB_4145 | - | 0.0 | 80.29% (477) | alpha,alpha-trehalose-phosphate synthase |
M. marinum M | MMAR_4978 | otsA | 0.0 | 82.74% (481) | alpha, alpha-trehalose-phosphate synthase |
M. avium 104 | MAV_0666 | otsA | 0.0 | 83.86% (477) | UDP-forming alpha,alpha-trehalose-phosphate synthase |
M. smegmatis MC2 155 | MSMEG_5892 | - | 0.0 | 84.45% (476) | alpha,alpha-trehalose-phosphate synthase (UDP-forming) |
M. ulcerans Agy99 | MUL_4052 | otsA | 0.0 | 82.54% (481) | alpha, alpha-trehalose-phosphate synthase |
M. vanbaalenii PYR-1 | Mvan_5192 | - | 0.0 | 80.84% (475) | Alpha,alpha-trehalose-phosphate synthase (UDP-forming) |
CLUSTAL 2.0.9 multiple sequence alignment Mb3520|M.bovis_AF2122/97 MAPSGGQEAQICDSET---FGDSDFVVVANRLPVDLERLPDGSTTWKRSP Rv3490|M.tuberculosis_H37Rv MAPSGGQEAQICDSET---FGDSDFVVVANRLPVDLERLPDGSTTWKRSP MMAR_4978|M.marinum_M MGPGGRQSAEPASTEV---FGDSDFVVVANRLPVDQERLPDGTIAWKRSP MUL_4052|M.ulcerans_Agy99 MGPGGRQSAEPASTEV---FGDSDFVVVANRLPVDQERLPDGTIAWKRSP MAV_0666|M.avium_104 MAPGGGRGSKTAS------YGNSDFVVVANRLPVDQERLPDGSTAWKRSP MLBr_02254|M.leprae_Br4923 MTSRGNHGSKTSSDKH---LGDSDFVVVANRLPVDQVRLPDGTAIWKRSP Mflv_1566|M.gilvum_PYR-GCK MTDQSGNGVRSGSASEAPPSAKADFVVVANRLPIDQVNLPDGSTEWKRSP Mvan_5192|M.vanbaalenii_PYR-1 MAPQSGPEARSG---------GADFVVVANRLPIDMVRRADGTTEFKRSP MSMEG_5892|M.smegmatis_MC2_155 MSPESGHETISG---------TSDFVVVANRLPVDLERLPDGTTRWKRSP TH_2241|M.thermoresistible__bu MADRGDSG-------------DSDFVVVANRLPIDLERAPDGTTSWKRSP MAB_4145|M.abscessus_ATCC_1997 MATQSDERSPVKPVTG-----TSDFVVVANRLPIDLVKLPDGSTTWKRSP * . :**********:* . .**: :**** Mb3520|M.bovis_AF2122/97 GGLVTALEPVLRRRRGAWVGWPGVNDDGAEPDLHVLDGPIIQDELELHPV Rv3490|M.tuberculosis_H37Rv GGLVTALEPVLRRRRGAWVGWPGVNDDGAEPDLHVLDGPIIQDELELHPV MMAR_4978|M.marinum_M GGLVTALEPLLRRRRGAWVGWAGVVEN----DVDVQDEPIVQDELQLQPV MUL_4052|M.ulcerans_Agy99 GGLVTALEPLLRRRRGAWVGWAGVVEN----DVDVQDEPIVQDELQLQPV MAV_0666|M.avium_104 GGLVTALEPLLRRQRGAWVGWPGIVDE----DVDHEDDPIVQDDLELRPV MLBr_02254|M.leprae_Br4923 GGLVTALEPLLRQRRGAWVGWPGVINDN--VDLDLTIKSIVQDGLTLYPV Mflv_1566|M.gilvum_PYR-GCK GGLVTALEPLLRRRHGAWIGWPGVPEDA--DDPDASTEPIEQDGMTLVPV Mvan_5192|M.vanbaalenii_PYR-1 GGLVTALEPLLRRRHGAWIGWPGVPEDA--DDPNAATEPIEQDGMTLVPV MSMEG_5892|M.smegmatis_MC2_155 GGLVTALEPLLRKRRGSWIGWAGVADSD--E------EPIVQDGLQLHPV TH_2241|M.thermoresistible__bu GGLVTALEPLLRRRRGAWIGWPGIPDSD--------EDPIVDGDLVLYPV MAB_4145|M.abscessus_ATCC_1997 GGLVTAMEPLLRKRRGAWVGWPGVPDAD--------VEPVSEDDMVLYSV ******:**:**:::*:*:**.*: : .: :. : * .* Mb3520|M.bovis_AF2122/97 RLSTTDIAQYYEGFSNATLWPLYHDVIVKPLYHREWWDRYVDVNQRFAEA Rv3490|M.tuberculosis_H37Rv RLSTTDIAQYYEGFSNATLWPLYHDVIVKPLYHREWWDRYVDVNQRFAEA MMAR_4978|M.marinum_M RLSADDVAQYYEGFSNATLWPLYHDVIVRPIYHREWWDRYVDVNRRFAEA MUL_4052|M.ulcerans_Agy99 RLSADDVAQYYEGFSNATLWPLYHDVIVRPIYHREWWDRYVDVNRRFAEA MAV_0666|M.avium_104 KLSADDVAEYYEGFSNATLWPLYHDVIVKPIYHREWWDRYVAVNRRFAEA MLBr_02254|M.leprae_Br4923 RLNTHDVAEYYEGFSNATLWPLYHDVIVKPIYHCEWWERYVDVNRRFAET Mflv_1566|M.gilvum_PYR-GCK RLSAADVAKYYEGFSNATLWPLYHDVIVKPTYHREWWERYVEVNRRFAEA Mvan_5192|M.vanbaalenii_PYR-1 RLSSEDVAEYYEGFSNATLWPLYHDVIVKPIYHREWWDRYVDVNRRFAEA MSMEG_5892|M.smegmatis_MC2_155 RLSADDVAKYYEGFSNATLWPLYHDLIVKPEYHREWWDRYVEVNRRFAEA TH_2241|M.thermoresistible__bu RLSADDVAQYYEGFSNATLWPLYHDVIVKPIYNRQWWERYVEVNRRFAEA MAB_4145|M.abscessus_ATCC_1997 RLSTQEVAEYYEGFSNATLWPLYHDVIVKPEYHREWWQAYVDVNRKFAEA :*.: ::*:****************:**:* *: :**: ** **::***: Mb3520|M.bovis_AF2122/97 ASRAAAHGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFMQ Rv3490|M.tuberculosis_H37Rv ASRAAAHGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFMQ MMAR_4978|M.marinum_M TARAAARGGTVWVQDYQLQLVPKMLRAMRPDLTIGFFLHIPFPPVELFMQ MUL_4052|M.ulcerans_Agy99 TARAAARGGTVWVQDYQLQLVPKMLRAMRPDLTIGFFLHIPFPPVELFMQ MAV_0666|M.avium_104 TSRAAARGATVWVQDYQLQLVPAMLRELRPDLTIGFFLHIPFPPVELFMQ MLBr_02254|M.leprae_Br4923 TSRTAAYGGTVWVQDYQLQLVPKMLRIMRPDLTIGFFLHIPFPPVELFMQ Mflv_1566|M.gilvum_PYR-GCK AARTAAEGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFLQ Mvan_5192|M.vanbaalenii_PYR-1 TAHTAAEGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFMQ MSMEG_5892|M.smegmatis_MC2_155 TARAAAEGATVWIQDYQLQLVPKMLRMLRPDVTIGFFLHIPFPPVELFMQ TH_2241|M.thermoresistible__bu TSRAAARGATVWVQDYQLQLVPKMLRELRPDLTIGFFLHIPFPPVELFMQ MAB_4145|M.abscessus_ATCC_1997 TAAVAAEGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFMQ :: .** *.***:********* *** :***:****************:* Mb3520|M.bovis_AF2122/97 MPWRTEIIQGLLGADLVGFHLPGGAQNFLILSRRLVGTDTSRGTVGVRSR Rv3490|M.tuberculosis_H37Rv MPWRTEIIQGLLGADLVGFHLPGGAQNFLILSRRLVGTDTSRGTVGVRSR MMAR_4978|M.marinum_M LPWRTEIIQGLLGADLVGFHLPGGAQNFLILSRRLVGADTSRGTVGVRSR MUL_4052|M.ulcerans_Agy99 LPWRTEIIQGLLGADLVGFHLPGGAQNFLILSRRLVGADTSRGTVGVRSR MAV_0666|M.avium_104 LPWRTEIVKGLLGADLVGFHLTGGAQNFLFLSRRLIGANTSRGAVGVRSR MLBr_02254|M.leprae_Br4923 IPWRTEIIEGLLGADLVGFHLTSGAQNFLFLSRHLLGANTSRGLVGVRSR Mflv_1566|M.gilvum_PYR-GCK MPWRTEIIEGLLGADLVGFHLPGGAQNFLILARRLLGAVTSRGNVGVRSR Mvan_5192|M.vanbaalenii_PYR-1 MPWRTEIIEGLLGADLVGFHLPGGAQNFLILARRLIGATTSRGNVGVRSR MSMEG_5892|M.smegmatis_MC2_155 MPWRTEIVEGLLGADLVGFHLPGGAQNFLVLSRRLVGANTSRASIGVRSR TH_2241|M.thermoresistible__bu LPWRTEITDGLLGADLVGFHLPGGAQNFLFLARRLVGANTSRASVGVRSK MAB_4145|M.abscessus_ATCC_1997 MPWRTEIVDGLLGADLIGFHLAGGAQNFMYLARRLVGASTSRASIGVRSR :****** .*******:****..*****: *:*:*:*: ***. :****: Mb3520|M.bovis_AF2122/97 FGAAVLGSRTIRVGAFPISVDSGALDHAARDRNIRRRAREIRTELGNPRK Rv3490|M.tuberculosis_H37Rv FGAAVLGSRTIRVGAFPISVDSGALDHAARDRNIRRRAREIRTELGNPRK MMAR_4978|M.marinum_M FGEVILGSRTIRVGAFPISIDSGALDQTARDRNIRRRSREIRAELGNPRK MUL_4052|M.ulcerans_Agy99 FGEVILGSRTIRVGAFPISIDSGALDQTARDRNIRRRSREIRAELGNPRK MAV_0666|M.avium_104 YGEVELESRVVRVGAFPISIDSTALDQTARHRDIRRRAREIRAELGNPRK MLBr_02254|M.leprae_Br4923 FGEVQLKSHTVQVGAFPISIDSKEIDQATRDRNVRRRAREIRAELGNPRK Mflv_1566|M.gilvum_PYR-GCK FGEVQFGFRKVKVGAFPISIDSAELDQHARTRATRQRAKEIRAELGNPRK Mvan_5192|M.vanbaalenii_PYR-1 FGEVQFGFRTVKVGAFPISIDSAELDQHARSRATRQRAKEIRAELGNPRK MSMEG_5892|M.smegmatis_MC2_155 FGEVQVGFRTVKVGAFPISIDSAELDGKARNRAIRQRARQIRAELGNPRK TH_2241|M.thermoresistible__bu FGEVQIGSRTVKVGAFPISIDSADLDRQARQRSIRQRARQIRAELGNPRR MAB_4145|M.abscessus_ATCC_1997 FGEIRVGFRTVKVGAFPISIDSTQLDSVSRSRQIRQRAKEIRAELGGPRK :* . : ::*******:** :* :* * *:*:::**:***.**: Mb3520|M.bovis_AF2122/97 ILLGVDRLDYTKGIDVRLKAFSELLAEGRVKRDDTVLVQLATPSRERVES Rv3490|M.tuberculosis_H37Rv ILLGVDRLDYTKGIDVRLKAFSELLAEGRVKRDDTVVVQLATPSRERVES MMAR_4978|M.marinum_M ILLGVDRLDYTKGIDVRLKAFSELLAEGRVKRDDTVLVQLATPSRERVES MUL_4052|M.ulcerans_Agy99 ILLGVDRLDYTKGIDVRLKAFSELLAEGRVKRDDTVLVQLATPSRERVES MAV_0666|M.avium_104 VLLGVDRLDYTKGIDVRLKAFSELLAEGRAKRDDTVLVQLATPSRERVDS MLBr_02254|M.leprae_Br4923 ILLGVDRLDYTKGIDVRLRAFAELLAEGRAKRDDTVLVQLATPSRERVES Mflv_1566|M.gilvum_PYR-GCK VLLGVDRLDYTKGIDVRLRAFSELLEEGRIDPEDTVLVQLATPSRERVQS Mvan_5192|M.vanbaalenii_PYR-1 ILLGVDRLDYTKGIDVRLRAFSELLEEGRIDPEDTVLVQLATPSRERVES MSMEG_5892|M.smegmatis_MC2_155 IMLGVDRLDYTKGIDVRLRALSELLEEKRIKRDDTVLVQLATPSRERVES TH_2241|M.thermoresistible__bu ILLGVDRLDYTKGIDVRLQAFAELLAEGRVNREDTVFVQLATPSRERVEA MAB_4145|M.abscessus_ATCC_1997 ILLGVDRLDYTKGIDIRLHAYEELLAEGRASREDTVFVQLATPSRERVDS ::*************:**:* *** * * . :***.***********:: Mb3520|M.bovis_AF2122/97 YQTLRNDIERQVGHINGEYGEVGHPVVHYLHRPAPRDELIAFFVASDVML Rv3490|M.tuberculosis_H37Rv YQTLRNDIERQVGHINGEYGEVGHPVVHYLHRPAPRDELIAFFVASDVML MMAR_4978|M.marinum_M YQTLRNDIERQVGHINGEYAEVGHPVVHYLHRPVPRNELIAFFVASDVML MUL_4052|M.ulcerans_Agy99 YQTLRNDIERQVGHINGEYAEVGHPVVHYLHRPVPRNELIAFFVASDVML MAV_0666|M.avium_104 YQQLRNDIERQVGHINGEYGEVGHPVVHYLHRPVPRNELIAFFVAADVML MLBr_02254|M.leprae_Br4923 YKILRNDIERQVGHINGEYGEVGHPVVHYLHRPIPRDELIAFYVASDVML Mflv_1566|M.gilvum_PYR-GCK YIEMREDIERQVGHVNGEFGKVGHPVLHYLHRPIPREDLVAFFVAADVML Mvan_5192|M.vanbaalenii_PYR-1 YVAMREDIERQVGHVNGEFGEVGHPVLHYLHRPIPREDLVAFFVAADVML MSMEG_5892|M.smegmatis_MC2_155 YIAMREDIERQVGHINGEYGEVGHPIVHYLHRPIPRDELIAFFVAADVML TH_2241|M.thermoresistible__bu YRLLRDDIERQVGHINGEYGEVGHPVVHYLHRPVPREELIAFFVAADVML MAB_4145|M.abscessus_ATCC_1997 YKKMRGDVEQQVGHINGEFGEVGHPVVHYLHRPVPREDLIAFFVAADVML * :* *:*:****:***:.:****::****** **::*:**:**:**** Mb3520|M.bovis_AF2122/97 VTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRHAYLVNPHDLE Rv3490|M.tuberculosis_H37Rv VTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRHAYLVNPHDLE MMAR_4978|M.marinum_M VTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRHAYLVNPHDLE MUL_4052|M.ulcerans_Agy99 VTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRHAYLVNPHDLE MAV_0666|M.avium_104 VTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRQAYLVNPHDLE MLBr_02254|M.leprae_Br4923 VTPLRDGMNLVAKEYVACRNDLGGALVLSEFTGAAAELRQAYLVNPHDLE Mflv_1566|M.gilvum_PYR-GCK VTPLRDGMNLVAKEYVACRHDLGGALVLSEFTGAAAELRQAYLTNPHHLE Mvan_5192|M.vanbaalenii_PYR-1 VTPLRDGMNLVAKEYVACRHDLGGALVLSEFTGAAAELRQAYLTNPHHIE MSMEG_5892|M.smegmatis_MC2_155 VTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRQAYLVNPHDLE TH_2241|M.thermoresistible__bu VTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELGQAYLVNPHNLD MAB_4145|M.abscessus_ATCC_1997 VTPLRDGMNLVAKEYVACRSDLGGSLVLSEFTGAAAELRQAYLVNPHDID ******************* ****:************* :***.***.:: Mb3520|M.bovis_AF2122/97 GVKDGIEEALNQTEEAGRRRMRSLRRQVLAHDVDRWAQSFLDALAGA--- Rv3490|M.tuberculosis_H37Rv GVKDGIEEALNQTEEAGRRRMRSLRRQVLAHDVDRWAQSFLDALAGA--- MMAR_4978|M.marinum_M GVKDGIEEALNQTEEAGRRRMRSMRRQVLAHDVDRWARSFLDALADS--- MUL_4052|M.ulcerans_Agy99 GVNDGIEEALNQTEEAGRRRMRSMRRQVLAHDVDRWARSFLDALADS--- MAV_0666|M.avium_104 GVKDTVEAALNQSVEEGRRRMRSLRRQVLAHDVDRWARSFLDALAES--- MLBr_02254|M.leprae_Br4923 GVKDTIEAALNQLAEEARRRMRSLRRQVLAHDVDRWARSFLDALAEA--- Mflv_1566|M.gilvum_PYR-GCK GVKDAIEAALNQSPEEGRRRMRALRRQVLAHDVDRWARSFLDALASR--- Mvan_5192|M.vanbaalenii_PYR-1 GVKDAIEAALTQAPEEGRRRMRAMRRQVLAHDVDRWARSFLDALASK--- MSMEG_5892|M.smegmatis_MC2_155 GVKDKIEAAVNQNPEEGKRRMRALRRQVLAHDVDRWARSFLDALAATGET TH_2241|M.thermoresistible__bu HVKDTMVAALNQTPEEGRRRMRALRRQVLAHDVDLWARSFLDALAST--- MAB_4145|M.abscessus_ATCC_1997 GVKDGIESALNQTPEEGRRRMRALRRQVLAHDVDRWARAFLEALSTP--- *:* : *:.* * .:****::********** **::**:**: Mb3520|M.bovis_AF2122/97 --HPRGQG------------- Rv3490|M.tuberculosis_H37Rv --HPRGQG------------- MMAR_4978|M.marinum_M --RPNDSADAAD--------- MUL_4052|M.ulcerans_Agy99 --RPNDSADAAD--------- MAV_0666|M.avium_104 --GPRDG-------------- MLBr_02254|M.leprae_Br4923 --PARDAT------------- Mflv_1566|M.gilvum_PYR-GCK --EPINEESH----------- Mvan_5192|M.vanbaalenii_PYR-1 --EPVEG-------------- MSMEG_5892|M.smegmatis_MC2_155 GDSGVTGESTPAPESDSGSF- TH_2241|M.thermoresistible__bu --RTGDADAVPV--------- MAB_4145|M.abscessus_ATCC_1997 --ATGDSIAPEQPAVLGGEPL