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M. thermoresistible (build 8) TH_2045 (mutT1)

annotation: POSSIBLE HYDROLASE MUTT1
coordinates: 4013302 - 4014234
length: 311

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2045mutT1-100% (311)POSSIBLE HYDROLASE MUTT1
M. thermoresistible (build 8)TH_0513-6e-1137.23% (94) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1543-1e-0530.69% (101) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3009mutT11e-11167.46% (295) hydrolase MutT1
M. gilvum PYR-GCKMflv_4224-1e-11767.58% (293) NUDIX hydrolase
M. tuberculosis H37RvRv2985mutT11e-11167.46% (295) hydrolase MutT1
M. leprae Br4923MLBr_01682-1e-10863.10% (290) hypothetical protein MLBr_01682
M. abscessus ATCC 19977MAB_3291-1e-10460.07% (303) MutT/NUDIX hydrolase
M. marinum MMMAR_1729mutT11e-10862.95% (305) hydrolase MutT1
M. avium 104MAV_3835-1e-11265.53% (293) hydrolase, NUDIX family protein
M. smegmatis MC2 155MSMEG_2390-1e-10762.84% (296) hydrolase, NUDIX family protein
M. ulcerans Agy99MUL_1971mutT11e-10962.95% (305) hydrolase MutT1
M. vanbaalenii PYR-1Mvan_2138-1e-12268.18% (308) NUDIX hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4224|M.gilvum_PYR-GCK          -----------------MT-KTSIMAAGAVLWR----PQDGT---DAPEI
Mvan_2138|M.vanbaalenii_PYR-1       ------MPKERKPGAVVVK-QSPILAAGAVLWR----PKEFT---GTPEI
TH_2045|M.thermoresistible__bu      ------VPKEVRPKTIPSDPASAVRAAGAVLWR----PGVDS---SAPEI
Mb3009|M.bovis_AF2122/97            -------MSIQNSSARRRSAGRIVYAAGAVLWR----PGSADSE-GPVEI
Rv2985|M.tuberculosis_H37Rv         -------MSIQNSSARRRSAGRIVYAAGAVLWR----PGSADSE-GPVEI
MMAR_1729|M.marinum_M               -------MSIPSSSVRRRSGDRIVYAAGAVLWR----PGKAK---GAIEI
MUL_1971|M.ulcerans_Agy99           -------MSIPSSSVRRRSGDRIVYAAGAVLWR----PGKAK---GAIEI
MAV_3835|M.avium_104                -------MPTQNSSTARRAGTRVVYAAGAVLWR----PGDAEPDGGDVEV
MLBr_01682|M.leprae_Br4923          -------MAIWNSSCQWPK-SQIVYAAGAVLWR----PGNSD---PAVEI
MSMEG_2390|M.smegmatis_MC2_155      MMPVDDLQEIPLSKDTTEKSKHTVRAAGAVLWRDASEHGGTTGHPATVEV
MAB_3291|M.abscessus_ATCC_1997      ------------MPDPISRTGAAVLAAGAALWRHQEHPEQDN-AAGAIEV
                                                           : ****.***               *:

Mflv_4224|M.gilvum_PYR-GCK          AIIHRPRYDDWSLPKGKVDPGETDTVATVREIGEETGFRSHLGRRLPTVT
Mvan_2138|M.vanbaalenii_PYR-1       AVIHRPRYDDWSLPKGKVDPGETEAVTAVREIAEETGYRAHLGRRLPTVT
TH_2045|M.thermoresistible__bu      AVIHRPRYDDWSLPKGKVDPGEIEPVTAVREIEEETGYRSVLGRELTEIT
Mb3009|M.bovis_AF2122/97            AVIHRPRYDDWSLPKGKVDPGETAPVGAVREILEETGHRANLGRRLLTVT
Rv2985|M.tuberculosis_H37Rv         AVIHRPRYDDWSLPKGKVDPGETAPVGAVREILEETGHRANLGRRLLTVT
MMAR_1729|M.marinum_M               ALIHRPRYDDWSLPKGKVDPGETAAVAAAREVCEETGQHAHLGRRLIMVS
MUL_1971|M.ulcerans_Agy99           ALIHRPRYDDWSLPKGKVDPGETAAVAAAREVCEETGQHAHLGRRLIMVS
MAV_3835|M.avium_104                AIIHRPRYDDWSLPKGKVDPGETAPVAAVREVREETGQCAVLGRRLDTVR
MLBr_01682|M.leprae_Br4923          AVIHRPRYDDWSLSKGKVDPGETAPMAAVREVFEETGHHATLGARLVVVN
MSMEG_2390|M.smegmatis_MC2_155      AVIHRPRYDDWSLPKGKLDQGETEPVAAAREIHEETGHTAVLGRRLGRVT
MAB_3291|M.abscessus_ATCC_1997      ALVHRPRYDDWSLPKGKLDPGETAAIAAVREIAEETGFTARLGRRLPSVS
                                    *::**********.***:* **  .: :.**: ****  : ** .*  : 

Mflv_4224|M.gilvum_PYR-GCK          YPVDG---AVKKVRYWAARAVGGEFVPNDEVDEMKWLPADRAIAELGYPH
Mvan_2138|M.vanbaalenii_PYR-1       YPVDT---DIKKVRYWAARCVGGEFAANDEVDELRWLPVAQAMSMLSYPH
TH_2045|M.thermoresistible__bu      YPLAN---GVKRVRYWAARALDGSFAPNDEVDELKWLPVSDALQRLDYPQ
Mb3009|M.bovis_AF2122/97            YPTDSPFRGVKKVHYWAARSTGGEFTPGSEVDELIWLPVPDAMNKLDYAQ
Rv2985|M.tuberculosis_H37Rv         YPTDSPFRGVKKVHYWAARSTGGEFTPGSEVDELIWLPVPDAMNKLDYAQ
MMAR_1729|M.marinum_M               YPVEQ---GLKKVYYWAARSLGGEFTAGNEVDKLIWLPVADAMTKLDYAQ
MUL_1971|M.ulcerans_Agy99           YPVEQ---GLKKVYYWAARSLGGEFTAGNEVDKLIWLPVADAMTKLDYAQ
MAV_3835|M.avium_104                YPIEQ---GVKKVYYWSARATGGEFVPGDEVDQLLWLPVTEAMQRLNYTQ
MLBr_01682|M.leprae_Br4923          YPIGQ---HVKKVYYWAARSIEGQFVPGSEVDELLWLPVVDAMKKLDYVQ
MSMEG_2390|M.smegmatis_MC2_155      YPIPQ---GTKRVWYWAAKSTGGDFSPNDEVDKLVWLPVDAAMDQLQYPD
MAB_3291|M.abscessus_ATCC_1997      YPVSQ---GTKRVKYWAAEALDGKFEANDEVDELRWLPVKDAIKTVSYAV
                                    **        *:* **:*..  *.* ...***:: ***.  *:  : *  

Mflv_4224|M.gilvum_PYR-GCK          DRKVVRRFLKLPADTKTVLIVRHGTAGDKKRYRGDDRKRPLDKHGRAQAE
Mvan_2138|M.vanbaalenii_PYR-1       DRKVLRRFQKLPADTQTVIIVRHGTAGDRSRYRGDDRNRPLDKHGRAQAE
TH_2045|M.thermoresistible__bu      DRDVLQRFAEHPARTRTVLIVRHATAGSRSRWQGDDRLRPLDKHGRAQAE
Mb3009|M.bovis_AF2122/97            DRKVLCRFAKHPADTQTVLVVRHGTAGSKAHFSGDDSKRPLDKRGRAQAE
Rv2985|M.tuberculosis_H37Rv         DRKVLCRFAKHPADTQTVLVVRHGTAGSKAHFSGDDSKRPLDKRGRAQAE
MMAR_1729|M.marinum_M               DRKVLRRFGKKPADTKTVLVVRHGSAGSKSRFSGDDTQRPLDKKGRAQAE
MUL_1971|M.ulcerans_Agy99           DRKVLRRFGKKPADTKTVLVVRHGSAGSKSRFSGDDTQRPLDKKGRAQAE
MAV_3835|M.avium_104                DRKVLRHFNKKPADTHTVLVVRHGTAGRKSRFSGDDAKRPLDKRGRAQAE
MLBr_01682|M.leprae_Br4923          DRKVLRQFAKQPAYTRTVLIVRHGTAGRKSRLSEDDTKRPLDKQGRAQAE
MSMEG_2390|M.smegmatis_MC2_155      DRKVLRRFVKRPVDTKTVLVVRHGTAGRRSRYKGDDRKRPLDKRGRAQAE
MAB_3291|M.abscessus_ATCC_1997      DRKVLRNFAKHQIDTRTLIIVRHAKAGRKERYSGDDTLRPLDKKGRAQAE
                                    **.*: .* :    *:*:::***..** : :   **  *****:******

Mflv_4224|M.gilvum_PYR-GCK          SLVGQLLAFGAAELFAADRVRCRQTLEPLAEELGVSIAGEPTLTEEAYAE
Mvan_2138|M.vanbaalenii_PYR-1       SLVGQLLAFGAEELFAADRVRCHQTLDPLAEELGAVIHDEPALTEEAYAD
TH_2045|M.thermoresistible__bu      ALVGVLLAFGADRLHAADRVRCEQTLEPLADEIAQPIHPEPTLNEESYTR
Mb3009|M.bovis_AF2122/97            ALVPQLLAFGATDVYAADRVRCHQTMEPLAAELNVTIHNEPTLTEESYAN
Rv2985|M.tuberculosis_H37Rv         ALVPQLLAFGATDVYAADRVRCHQTMEPLAAELNVTIHNEPTLTEESYAN
MMAR_1729|M.marinum_M               ALVPQLLAFGADTVYAADRLRCHQTVQPLAEELGVVIHNERTLTEEAYAK
MUL_1971|M.ulcerans_Agy99           ALVPQLLAFGADTVYAADRLRCHQTVQPLAEELGVVIHNERTLTEEAYAK
MAV_3835|M.avium_104                ALVPQLLAFGASQVHAADRVRCHQTVQPLAEELDVPVHNETTLTEEAYAK
MLBr_01682|M.leprae_Br4923          ALIGQLLAFGATDVYAADQLHCHQTVEPLAAELGVPIHNEPSLTKEAFAK
MSMEG_2390|M.smegmatis_MC2_155      ALVAQLMAFGATTLYAADRVRCHQTIEPLAQELDQLIHNEPLLTEEAYAA
MAB_3291|M.abscessus_ATCC_1997      ALTGQLLAFGASAIHAADRLRCRQTVEPLAEELNTVIFSEPALSEEAYWA
                                    :*   *:****  :.***:::*.**::*** *:   :  *  *.:*::  

Mflv_4224|M.gilvum_PYR-GCK          DRKAARARILDIAETAGTPVICSQGKVIPDLIAWWCERDGVRADKSRNRK
Mvan_2138|M.vanbaalenii_PYR-1       DRKAARQRILEIAEKSAAPVICTQGKVIPDLITWWCERDGVRPDKSRNRK
TH_2045|M.thermoresistible__bu      NRTAGRQRLLEIAAAGGTPVVCTQGKVIPDLIAWWCERDGVRPADTENRK
Mb3009|M.bovis_AF2122/97            NPKRGRHRVLQIVEQVGTPVICTQGKVIPDLITWWCERDGVHPDKSRNRK
Rv2985|M.tuberculosis_H37Rv         NPKRGRHRVLQIVEQVGTPVICTQGKVIPDLITWWCERDGVHPDKSRNRK
MMAR_1729|M.marinum_M               NAKRGRQRLLQIATRDGTPVICSQGKVIPDLIAWWCERDGVRSDRSRNHK
MUL_1971|M.ulcerans_Agy99           NAKRGRQRLLQIATRDGTPVICSQGKVIPDLIAWWCERDGVRSDRSRNHK
MAV_3835|M.avium_104                NPKRARHRMLEIAGEPGTPVVCTQGKVIPDLIAWWCDRDGVRPDKSRNHK
MLBr_01682|M.leprae_Br4923          NPKRGLHRVLRIAAQSGTPVICLQGKIIPDLIAWWCERDGVRPKKSHNYK
MSMEG_2390|M.smegmatis_MC2_155      DHKAARKRLLEIAGRPGNPVICTQGKVIPGLIEWWCERAKVRPETTGNRK
MAB_3291|M.abscessus_ATCC_1997      DRKRAHRRVLEIAELDGIRVLCTQGKVIPDLIEWWAQRDGVRPDKSRNRK
                                    : . .  *:* *.   .  *:* ***:**.** **.:*  *:.  : * *

Mflv_4224|M.gilvum_PYR-GCK          GSTWVLSLAEGRLVAADHLSSALPPKK--
Mvan_2138|M.vanbaalenii_PYR-1       GSTWVMSLSDGRLVAADHISSPLPPKK--
TH_2045|M.thermoresistible__bu      GSVWVMSLVEGRLIAADHIASPLPVR---
Mb3009|M.bovis_AF2122/97            GSTWVLSLSAGRLVTADHIGGALAANVRA
Rv2985|M.tuberculosis_H37Rv         GSTWVLSLSAGRLVTADHIGGALAANVRA
MMAR_1729|M.marinum_M               GSTWVLSLSGGRVIAADHIGGALAANVRA
MUL_1971|M.ulcerans_Agy99           GSTWVLSLSGGRVIAADHIGGALAANVRA
MAV_3835|M.avium_104                GSTWVLSLSAGRLVAADHIGGALAANVRA
MLBr_01682|M.leprae_Br4923          GSTWVLSLLAGQLVAVDHVGSTLAANVQP
MSMEG_2390|M.smegmatis_MC2_155      GSTWVLSLSDGELVGADYLS---PPDEK-
MAB_3291|M.abscessus_ATCC_1997      GSMWVLSMRGQKLLAADHLDSPLPAGS--
                                    ** **:*:   .:: .*::    .