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M. thermoresistible (build 8) TH_2005 (lysA)

annotation: PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE)
coordinates: 3902490 - 3903908
length: 473

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2005lysA-100% (473)PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1325lysA0.082.29% (446) diaminopimelate decarboxylase LysA
M. gilvum PYR-GCKMflv_2297-0.082.63% (472) diaminopimelate decarboxylase
M. tuberculosis H37RvRv1293lysA0.082.29% (446) diaminopimelate decarboxylase LysA
M. leprae Br4923MLBr_01128lysA0.080.30% (472) diaminopimelate decarboxylase
M. abscessus ATCC 19977MAB_1434-0.075.00% (472) diaminopimelate decarboxylase
M. marinum MMMAR_4104lysA0.081.14% (472) diaminopimelate decarboxylase LysA
M. avium 104MAV_1508lysA0.083.05% (472) diaminopimelate decarboxylase
M. smegmatis MC2 155MSMEG_4958lysA0.083.69% (472) diaminopimelate decarboxylase
M. ulcerans Agy99MUL_3971lysA0.080.93% (472) diaminopimelate decarboxylase LysA
M. vanbaalenii PYR-1Mvan_4349-0.083.23% (471) diaminopimelate decarboxylase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2297|M.gilvum_PYR-GCK          MIAHPAGPRHAEEVPSAAAPERPQSAADVSRLAPNVWPQNTVRGDDGAVS
Mvan_4349|M.vanbaalenii_PYR-1       MIAHPAGPRHAEEVHPVATPDRPRTAAEVLQLAPNVWPQNAVRGADGVVS
MMAR_4104|M.marinum_M               MNVHPAGPRHAEESRHPESPQRPQSAEELLYLAPNVWPRNTTRDEQGCAR
MUL_3971|M.ulcerans_Agy99           MNVHPAGPRHAEESRHPESPQRPQSAEELLYLAPNVWPRNTARDEQGCAR
Mb1325|M.bovis_AF2122/97            -------------------------MNELLHLAPNVWPRNTTRDEVGVVC
Rv1293|M.tuberculosis_H37Rv         -------------------------MNELLHLAPNVWPRNTTRDEVGVVC
MLBr_01128|M.leprae_Br4923          MNVHTAGPRHAEKTRHTATPQRVQPSDDLLRLASNVWPRNITRDETGVAC
MAV_1508|M.avium_104                MNVHPAGPRHAEETRHPESPPRPQSPEELLLLAPNVWPRNATRNEAGVAT
TH_2005|M.thermoresistible__bu      VIAHPAGPRHAEEIHHGETPPRPQSPDELLLLAPNVWPRNTVRESDGVVS
MSMEG_4958|M.smegmatis_MC2_155      MNAHPAGPRHAEELHHADVPDKPQSPDEIMLLAPNVWPRNLVRGADGVVT
MAB_1434|M.abscessus_ATCC_1997      MSAHPAGPRHAEGEQHTAMSSAP--PANPTELASNVWPRNASRGADGEVT
                                                               :   **.****:*  *   * . 

Mflv_2297|M.gilvum_PYR-GCK          IAGVPVADIAAEFGTPVFVIDEADFRSRCRDISSAFGGGEYVHYAAKAFL
Mvan_4349|M.vanbaalenii_PYR-1       IAGVSVADIAAEFGTPVFVIDEADFRARCRDIAAAFGGGEHVRYAAKAFL
MMAR_4104|M.marinum_M               IAGVPLTELAREYGTPLFVIDEDDFRSRCQEIAAAFGGGHNVNYAAKAFL
MUL_3971|M.ulcerans_Agy99           IAGVPLTELAREYGTPLFVIDEDDFRSRCQEIAAAFGGGHNVNYAAKAFL
Mb1325|M.bovis_AF2122/97            IAGIPLTQLAQEYGTPLFVIDEDDFRSRCRETAAAFGSGANVHYAAKAFL
Rv1293|M.tuberculosis_H37Rv         IAGIPLTQLAQEYGTPLFVIDEDDFRSRCRETAAAFGSGANVHYAAKAFL
MLBr_01128|M.leprae_Br4923          IAGNKLTDLAGEYGTPLFVIDEDDFRFRCREIAAAFGGGENVHYAAKAFL
MAV_1508|M.avium_104                IAGVAVTELAREYGTPLFVVDEDDFRSRCREIASAFGGGNNVHYAAKAFL
TH_2005|M.thermoresistible__bu      IAGVRVTDIADEYGTPTFVIDEDDFRSRCREMAAAFGGGENVHYAAKAFL
MSMEG_4958|M.smegmatis_MC2_155      IAGVPVTDLAAKFGTPLFVIDEDDFRTRCRDIAAAFGGGQYVHYAAKAFL
MAB_1434|M.abscessus_ATCC_1997      LAGLAVSELAEQYGTPLFVIDEDDFRSRCRDMAAAFGGAARVHYASKAFL
                                    :**  ::::* ::*** **:** *** **:: ::***..  *.**:****

Mflv_2297|M.gilvum_PYR-GCK          CGEIARWVDEEGLSLDVATGGELAVALHAGFPAERITVHGNNKSVAELTA
Mvan_4349|M.vanbaalenii_PYR-1       CTEVARWIDEEGLSLDVASGGELAVALHAGFPAERIALHGNNKSVAELTA
MMAR_4104|M.marinum_M               CSEIARWVNEEGLSIDVSTGGELAVALHANFPPERITLHGNNKSVAELTT
MUL_3971|M.ulcerans_Agy99           CSEIARWVNEEGLSIDVSTGGELAVALHANFPPERITLHGNNKSVAELTT
Mb1325|M.bovis_AF2122/97            CSEVARWISEEGLCLDVCTGGELAVALHASFPPERITLHGNNKSVSELTA
Rv1293|M.tuberculosis_H37Rv         CSEVARWISEEGLCLDVCTGGELAVALHASFPPERITLHGNNKSVSELTA
MLBr_01128|M.leprae_Br4923          CTEIARWIDEEGLSLDVCSGGELAVALHASFPPERISLHGNNKSVAELKD
MAV_1508|M.avium_104                CSEVARWIDEEGLSLDVCTGGELAVALHADFPPERITFHGNNKSVAELTA
TH_2005|M.thermoresistible__bu      CTEIARWIDEEGLCLDVASGGELAVALHAGFPAERITLHGNNKSVEELTT
MSMEG_4958|M.smegmatis_MC2_155      CSEIARWVDEEGLSLDVATGGELAVALHAGFPASRITVHGNNKSVAELTA
MAB_1434|M.abscessus_ATCC_1997      CTEVARWIKDEGLGLDVCSAGELAVALRAEFPPERIALHGNNKSEAELAQ
                                    * *:***:.:*** :**.:.*******:* **..**:.******  **  

Mflv_2297|M.gilvum_PYR-GCK          AVKHGVGHVVVDSMIEIERLDRIAADNGVVQDVLVRVTVGVEAHTHEFIS
Mvan_4349|M.vanbaalenii_PYR-1       AVEAGIEHVVVDSMTEIDRLDKIAGEAGVVQDVLIRVTVGVEAHTHEFIS
MMAR_4104|M.marinum_M               AVKAGVGHIVLDSMIEIERLDAIAGEAGIVQDVFVRLTVGVEAHTHEFIS
MUL_3971|M.ulcerans_Agy99           AVKAGVGHIVLDSMIEIERLDAIAGEAGIVQDVFVRLTVGVEAHTHEFIS
Mb1325|M.bovis_AF2122/97            AVKAGVGHIVVDSMTEIERLDAIAGEAGIVQDVLVRLTVGVEAHTHEFIS
Rv1293|M.tuberculosis_H37Rv         AVKAGVGHIVVDSMTEIERLDAIAGEAGIVQDVLVRLTVGVEAHTHEFIS
MLBr_01128|M.leprae_Br4923          AVKAGVGYIVLDSTTEIERLDAIAGEAGIVQDVLVRLTVGVEAHTHEFIA
MAV_1508|M.avium_104                AVKAGVGHVVLDSMTEIERLDAIAADAGIVQDVFVRLTVGVEAHTHEFIS
TH_2005|M.thermoresistible__bu      AVEAGVGHVVLDSMIEIERLDRIAAAAGKVQDVLVRVTVGVEAHTHEFIS
MSMEG_4958|M.smegmatis_MC2_155      AVQAGVGHVVLDSEIEIERLDQIAGAAGVVQDVLVRVTVGVEAHTHEFIS
MAB_1434|M.abscessus_ATCC_1997      AVQAGVGHIVVDSMIEIDRLDAIAGRAGVVQDVLVRVTVGVEAHTHEFIS
                                    **: *: ::*:**  **:*** **.  * ****::*:************:

Mflv_2297|M.gilvum_PYR-GCK          TAHEDQKFGLSLASGAAMEAVRRVFEAGNLRLVGLHSHIGSQIFDVAGFE
Mvan_4349|M.vanbaalenii_PYR-1       TAHEDQKFGLSLASGAAMTAVRRVFETDHLRLVGLHSHIGSQIFDVAGFE
MMAR_4104|M.marinum_M               TAHEDQKFGLSISSGAAMAAVRRVFATDHLRLVGLHSHIGSQIFDVDGFE
MUL_3971|M.ulcerans_Agy99           TAHEDQKFGLSISSGAAMAAVRRVFATDHLRLVGLHSHIGSQIFDVDGFE
Mb1325|M.bovis_AF2122/97            TAHEDQKFGLSVASGAAMAAVRRVFATDHLRLVGLHSHIGSQIFDVDGFE
Rv1293|M.tuberculosis_H37Rv         TAHEDQKFGLSVASGAAMAAVRRVFATDHLRLVGLHSHIGSQIFDVDGFE
MLBr_01128|M.leprae_Br4923          TAHEDQKFGLSVASGAAMAAVRRVFATDNLRLVGLHSHIGSQIFDVAGFE
MAV_1508|M.avium_104                TAHEDQKFGLSVASGSALAAVGRVFDTEHLRLVGLHSHIGSQIFDVAGFE
TH_2005|M.thermoresistible__bu      TAHEDQKFGLSLASGAAMAAVRRVFATDNLRLVGLHSHIGSQIFDVAGFE
MSMEG_4958|M.smegmatis_MC2_155      TAHEDQKFGLSLATGAAMNAIRRVFATDNLRLVGLHSHIGSQIFDVAGFE
MAB_1434|M.abscessus_ATCC_1997      TAHEDQKFGLSLAGGQALEAVRRVFATDNLRLVGLHSHIGSQIFDVDGFE
                                    ***********:: * *: *: *** : :***************** ***

Mflv_2297|M.gilvum_PYR-GCK          IAAHRVIGLLRDVVAEFGVEKTSQMDIVDLGGGLGISYLPDDNPPPMSEL
Mvan_4349|M.vanbaalenii_PYR-1       LAAHRVIGLLRDAVAEFGVEKTSQMSIVDLGGGLGISYLPHDDPPPMGEL
MMAR_4104|M.marinum_M               LAAHRVIGLLREVVAEFGSEKTAQLATVDLGGGLGISYLSSDDPPPVGEL
MUL_3971|M.ulcerans_Agy99           LAAHRVIGLLREVVAEFGSEKTAQLAMVDLGGGLGISYLSSDDPPPVGEL
Mb1325|M.bovis_AF2122/97            LAAHRVIGLLRDVVGEFGPEKTAQIATVDLGGGLGISYLPSDDPPPIAEL
Rv1293|M.tuberculosis_H37Rv         LAAHRVIGLLRDVVGEFGPEKTAQIATVDLGGGLGISYLPSDDPPPIAEL
MLBr_01128|M.leprae_Br4923          LAAHRVIGLLCDIVGEFDPEKTAQLSIVDLGGGLGISYLPDDDPPPIFEL
MAV_1508|M.avium_104                LAARRVIGLLHDAVEQFGVEKTAQIATVDLGGGLGISYLAADDPPPMGEL
TH_2005|M.thermoresistible__bu      LAAHRVIGLLHDVVEEFGVEKTAQISTVDLGGGLGISYLPDDDPPPVEEL
MSMEG_4958|M.smegmatis_MC2_155      IAAHRVIGLLRDVVAEFGVEKTSQMSIVDLGGGLGISYLPHDDPPPMKEL
MAB_1434|M.abscessus_ATCC_1997      VAAHRVIGLLRDVVAEFGTDKTAQLNIIDLGGGLGISYVPSDDPPPIEDL
                                    :**:****** : * :*. :**:*:  :**********:. *:***: :*

Mflv_2297|M.gilvum_PYR-GCK          AAKLRAIVARESAAVGLPAPKLVVEPGRAIAGPGTITLYEVGTVKDVAVS
Mvan_4349|M.vanbaalenii_PYR-1       ADKLHAIVRHESAAVGLPAPRLVVEPGRAIAGPGTITLYEVGTVKDVAIS
MMAR_4104|M.marinum_M               ADKLGAIVSNESAAVGLPAPRLVVEPGRAIAGPGTITLYEVGTVKDVDVS
MUL_3971|M.ulcerans_Agy99           ADKLGAIVSNESAAVGLPAPRLVVEPGRAIAGPGTITLYEVGTVKDVDVS
Mb1325|M.bovis_AF2122/97            AAKLGTIVSDESTAVGLPTPKLVVEPGRAIAGPGTITLYEVGTVKDVDVS
Rv1293|M.tuberculosis_H37Rv         AAKLGTIVSDESTAVGLPTPKLVVEPGRAIAGPGTITLYEVGTVKDVDVS
MLBr_01128|M.leprae_Br4923          AAKLGAIVSNESAAVGLPVPKLMVEPGRAIAGPGTITLYEVGTIKDVDVS
MAV_1508|M.avium_104                AGKLSAIVQHESAAVGLPTPRLVVEPGRAIAGPGTITLYEVGTVKDVDVS
TH_2005|M.thermoresistible__bu      AAKLKAIVRSESAAVGLPTPRLVVEPGRAIAGPGTITLYRVGTVKDVAIS
MSMEG_4958|M.smegmatis_MC2_155      ADKLLEIVRTESAAVGLPTPKLVVEPGRAIAGPGTITLYEVGTVKDVAVS
MAB_1434|M.abscessus_ATCC_1997      AAKLGVIVRTESALAGLPGPRLVIEPGRAIAGPGTVTLYRVGTTKDVILS
                                    * **  **  **: .*** *:*::***********:***.*** *** :*

Mflv_2297|M.gilvum_PYR-GCK          PTSHRRYVSVDGGMSDNIRTSLYGAEYDVRLLSRVSDATPTLSRVVGKHC
Mvan_4349|M.vanbaalenii_PYR-1       SDRNRRYVSVDGGMSDNIRTSLYDAEYDVRLVSRTSNAEPTLSRVVGKHC
MMAR_4104|M.marinum_M               ATANRRYVSVDGGMSDNIRTALYDAQYDVRLVSRVSDAPATLARVVGKHC
MUL_3971|M.ulcerans_Agy99           ATANRRYVSVDGGMSDNIRTALYDAQYDVRLVSRVSDAPAMLARVVGKHC
Mb1325|M.bovis_AF2122/97            ATAHRRYVSVDGGMSDNIRTALYGAQYDVRLVSRVSDAPPVPARLVGKHC
Rv1293|M.tuberculosis_H37Rv         ATAHRRYVSVDGGMSDNIRTALYGAQYDVRLVSRVSDAPPVPARLVGKHC
MLBr_01128|M.leprae_Br4923          ATAHRRYVSIDGGMSDNIRTALYDAQYDVRLVSRTSDAPAAPASIVGKHC
MAV_1508|M.avium_104                ATAHRRYVSVDGGMSDNIRTALYDAQYDARLVSRVSDAPAELARIVGKHC
TH_2005|M.thermoresistible__bu      PTAYRRYVSVDGGMSDNIRTALYGAQYDARLVSRRTDAEPALGRIVGKHC
MSMEG_4958|M.smegmatis_MC2_155      QTAHRRYVSVDGGMSDNIRTSLYAAQYDARLVSRVSDAPPALARIVGKHC
MAB_1434|M.abscessus_ATCC_1997      -NGQRRYVSVDGGMSDNIRTSLYQAEYHPQLVSRDSDVAPVLSRVVGKHC
                                        *****:**********:** *:*. :*:** ::. .  . :*****

Mflv_2297|M.gilvum_PYR-GCK          ESGDIVVRDAWLSEDVRPGDLLGVAATGAYCYSMSSRYNLIGRPAVVAVR
Mvan_4349|M.vanbaalenii_PYR-1       ESGDIVVRDAWIPDDVGPGDLLGVAATGAYCYSMSSRYNLIGRPAVVAVR
MMAR_4104|M.marinum_M               ESGDIIVRDTWVPDDLQPGDLVAVAATGAYCYSLSSRYNMIGRPAVVAVR
MUL_3971|M.ulcerans_Agy99           ESGDIIVRDTWVPDDLQPGDLVAVAATGAYCYSLSSRYNMIGRPAVVAVR
Mb1325|M.bovis_AF2122/97            ESGDIIVRDTWVPDDIRPGDLVAVAATGAYCYSLSSRYNMVGRPAVVAVH
Rv1293|M.tuberculosis_H37Rv         ESGDIIVRDTWVPDDIRPGDLVAVAATGAYCYSLSSRYNMVGRPAVVAVH
MLBr_01128|M.leprae_Br4923          ESGDIVVRDTWVPDDLKPGDLVGVAATGAYCYSLSSRYNMLGRPAVVAVC
MAV_1508|M.avium_104                ESGDIVVRDTWVPGDLRPGDLIGVAATGAYCYSLSSRYNMVCRPAVVAVR
TH_2005|M.thermoresistible__bu      ESGDIVVRDVWVPGDVQPGDLIGVAATGAYCYSMSSRYNLIGRPAVVVVR
MSMEG_4958|M.smegmatis_MC2_155      ESGDIVVRDTWVSDDIAPGDLIGVAATGAYCYSMSSRYNLLCRPAVVAVA
MAB_1434|M.abscessus_ATCC_1997      ESGDIVVRDAWLPEDVAPGDLLAVAATGAYCYSMSSRYNLLTRPAVIAVK
                                    *****:***.*:. *: ****:.**********:*****:: ****:.* 

Mflv_2297|M.gilvum_PYR-GCK          DGRARLILRRETVEDLLSLEVR----
Mvan_4349|M.vanbaalenii_PYR-1       DGRARLILRRETFDDLLSLEVSEVKR
MMAR_4104|M.marinum_M               AGKARLVLRRETVDDLLSLEVR----
MUL_3971|M.ulcerans_Agy99           AGKARLVLRRETVDDLLSLEVR----
Mb1325|M.bovis_AF2122/97            AGNARLVLRRETVDDLLSLEVR----
Rv1293|M.tuberculosis_H37Rv         AGNARLVLRRETVDDLLSLEVR----
MLBr_01128|M.leprae_Br4923          AGQARLILRRETVDDLLSLEVR----
MAV_1508|M.avium_104                DGRARLVLRRETVDDLLSLEVR----
TH_2005|M.thermoresistible__bu      DGRARLILRRETVDDLLSLEVR----
MSMEG_4958|M.smegmatis_MC2_155      DGQARLVLRRETVEDLLSLEVKGQ--
MAB_1434|M.abscessus_ATCC_1997      DGRARLILRRETVEDLVSLEVSE---
                                     *.***:*****.:**:****