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M. thermoresistible (build 8) TH_1912 (purU)

annotation: PROBABLE FORMYLTETRAHYDROFOLATE DEFORMYLASE PURU (FORMYL-FH(4) HYDROLASE)
coordinates: 3724801 - 3725688
length: 296

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1912purU-100% (296)PROBABLE FORMYLTETRAHYDROFOLATE DEFORMYLASE PURU (FORMYL-FH(4) HYDROLASE)
M. thermoresistible (build 8)TH_1361purN6e-1138.74% (111) PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN
M. thermoresistible (build 8)TH_1529fmt9e-0729.03% (124) PROBABLE METHIONYL-TRNA FORMYLTRANSFERASE FMT

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2988purU1e-12674.40% (293) formyltetrahydrofolate deformylase
M. gilvum PYR-GCKMflv_5090purU1e-13682.27% (282) formyltetrahydrofolate deformylase
M. tuberculosis H37RvRv2964purU1e-12674.40% (293) formyltetrahydrofolate deformylase
M. leprae Br4923MLBr_00160purN9e-1238.98% (118) phosphoribosylglycinamide formyltransferase
M. abscessus ATCC 19977MAB_1306purU1e-11871.28% (282) formyltetrahydrofolate deformylase
M. marinum MMMAR_1753purU1e-12374.47% (282) formyltetrahydrofolate deformylase PurU
M. avium 104MAV_1080purN7e-1141.24% (97) phosphoribosylglycinamide formyltransferase
M. smegmatis MC2 155MSMEG_2200purU1e-13681.57% (293) formyltetrahydrofolate deformylase
M. ulcerans Agy99MUL_4713purN9e-1240.21% (97) phosphoribosylglycinamide formyltransferase
M. vanbaalenii PYR-1Mvan_1265purU1e-13682.27% (282) formyltetrahydrofolate deformylase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2988|M.bovis_AF2122/97            MGKGSMTAHATPNEPDYPPPPGGPPPPADIGRLLLRCHDRPGIIAAVSTF
Rv2964|M.tuberculosis_H37Rv         MGKGSMTAHATPNEPDYPPPPGGPPPPADIGRLLLRCHDRPGIIAAVSTF
MMAR_1753|M.marinum_M               MSQN------------FPPPPGGPPQPADIGRLLLRCHDHPGIIAAVSTF
TH_1912|M.thermoresistible__bu      ---------------VYPRSDHAELPVADVGRLLLRCPDRPGLVAAVSAF
MSMEG_2200|M.smegmatis_MC2_155      -----------MMAQEYPKAN--ALPAQDVGRLLLRCADRPGLVAAISGF
Mflv_5090|M.gilvum_PYR-GCK          ---------------MVEHTDADIHGPKDIGRLLLRCADRPGLIAAVSGF
Mvan_1265|M.vanbaalenii_PYR-1       ---------------MVEHTDADIHGPRDIGRLLLRCADRPGLIAAVSGF
MAB_1306|M.abscessus_ATCC_1997      ----------MFPQGMHPTGSSDAFHSKDIGRLLLQCPDRIGVVAAVSAF
MLBr_00160|M.leprae_Br4923          --------------------------------------------------
MAV_1080|M.avium_104                --------------------------------------------------
MUL_4713|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mb2988|M.bovis_AF2122/97            LARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQRDFGSTVA
Rv2964|M.tuberculosis_H37Rv         LARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQRDFGSTVA
MMAR_1753|M.marinum_M               LTQAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAIDELQREFGSAVA
TH_1912|M.thermoresistible__bu      LAEAGANIISLDQHSTEQTGGIFMQRTIFHLPGLPAVRDTLEREFAERVA
MSMEG_2200|M.smegmatis_MC2_155      LTAAGANIVSLDQHSTEQAGGTFIQRTIFHLPGLTAVRDELERSFREQVA
Mflv_5090|M.gilvum_PYR-GCK          LTQTGANIISLDQHSTEPVGGTFMQRTIFHLPGLTAARDGLEREFAEKVA
Mvan_1265|M.vanbaalenii_PYR-1       LTQTGANIISLDQHSTEPVGGTFMQRTIFHLPGLPAARDGLERDFAAQVA
MAB_1306|M.abscessus_ATCC_1997      LAEAGASIISLAQYSTEPQGGWFMQRTVFHRSGLAAARDAMEAKFAS-IA
MLBr_00160|M.leprae_Br4923          -----------------------MQEPLCVSP------------------
MAV_1080|M.avium_104                -----------------------MVEPLHVPP------------------
MUL_4713|M.ulcerans_Agy99           -----------------------MQEPVRVPP------------------
                                                           : ..:   .                  

Mb2988|M.bovis_AF2122/97            DKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIA
Rv2964|M.tuberculosis_H37Rv         DKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIA
MMAR_1753|M.marinum_M               DKFDIDYRFTEAAKPKRVAIMASKEDHCLLDLLWRNRRGELEMSVAMVIA
TH_1912|M.thermoresistible__bu      GRFGMDFKLTEAARPKRVAIMASREDHCLLDLLWRNRRGELNMTVVMVIA
MSMEG_2200|M.smegmatis_MC2_155      GPFEMDFTLTEAAKPKRVALMASREDHCLLDLLWRNRRGELPMSVVMVIA
Mflv_5090|M.gilvum_PYR-GCK          EPFGIDFRLTEAAKPKRVAIMASREDHCLLDLLWRNRRGELDMSVVMVIA
Mvan_1265|M.vanbaalenii_PYR-1       DPFGMDFRLTEAAKPKRVAIMASREDHCLLDLLWRNRRGELDMSVVMVIA
MAB_1306|M.abscessus_ATCC_1997      EEFDIQYRFSEAAKPKRVAIMVSRTDHCLLDLLWRNRRGELDMSIAMVIS
MLBr_00160|M.leprae_Br4923          ------------SAPSRVVVLASG-TGSLLGSLIDASVGNYPARVVAVGV
MAV_1080|M.avium_104                ------------NAPARVVVLASG-TGSLLSSLIDAAVGDYPARVVAVGA
MUL_4713|M.ulcerans_Agy99           ------------SAPARLVVLASG-TGSLLNSLLDAAVADYPARIVAVGV
                                                  * *:.::.*    .**. *     .:    :. *  

Mb2988|M.bovis_AF2122/97            NHPDLAAHVRPFG-VPFIHIPATRDTRTEAEQRQLQLLSG--NVDLVVLA
Rv2964|M.tuberculosis_H37Rv         NHPDLAAHVRPFG-VPFIHIPATRDTRTEAEQRQLQLLSG--NVDLVVLA
MMAR_1753|M.marinum_M               NHADLADHVRPFG-VPFIHIPVTRDTRADAEQRQLQLLSG--NVDLVILA
TH_1912|M.thermoresistible__bu      NHPELADQVRPFD-VPFIHVPASKEIREQAEQRQLELLRG--NVDLVVLA
MSMEG_2200|M.smegmatis_MC2_155      NHPDLAEQVRAFG-VPFIYVPATKENRAEAEQRLLELLRG--NVDLVVLA
Mflv_5090|M.gilvum_PYR-GCK          NHPDLADAVRPFG-VPFIHVPARTEIRDEAEQRQLDLLRG--NVDLVVLA
Mvan_1265|M.vanbaalenii_PYR-1       NHPDLADAVRPFG-VPFIHVPARTEIRDEAEQRQLDLLRG--NVDLVVLA
MAB_1306|M.abscessus_ATCC_1997      NHPDLADQVRSFG-LPFVHIPATRENRADAERKQLELLQG--NVDLVVLA
MLBr_00160|M.leprae_Br4923          DRDCGATKIAKAASVPTFTVRLADPPGRDAWDAKITEAVASYKPDLVVLA
MAV_1080|M.avium_104                DRDCLATQIAAAASLPSFTVRLGDHPDRAAWDAAITEATAAHSPDLVVSA
MUL_4713|M.ulcerans_Agy99           DRDCRATEVAAQASVPAFTVRVSDHPSRDAWNAAITAATAAHSPDLVVSA
                                    ::   *  :     :* . :         *    :    .  . ***: *

Mb2988|M.bovis_AF2122/97            RYMQILSPGFLEAIGCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATA
Rv2964|M.tuberculosis_H37Rv         RYMQILSPGFLEAIGCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATA
MMAR_1753|M.marinum_M               RYMQILSPAFLDAIGCPLINIHHSFLPAFTGASPYKRARERGVKLIGATA
TH_1912|M.thermoresistible__bu      RYMQILTPRFLDEVGVPLINIHHSFLPAFIGAAPYQQAKDRGVKLIGATA
MSMEG_2200|M.smegmatis_MC2_155      RYMQILTPEFLDAVGCPLINIHHSFLPAFIGAAPYRRAKERGVKLVGATA
Mflv_5090|M.gilvum_PYR-GCK          RYMQILTPGFIEQVGCPLINIHHSFLPAFIGASPYRRAKERGVKLVGATA
Mvan_1265|M.vanbaalenii_PYR-1       RYMQILTPSFIEQVGCPLINIHHSFLPAFIGASPYRRAKERGVKLVGATA
MAB_1306|M.abscessus_ATCC_1997      RYMQILSPEFLNEIDCPLINIHHSFLPAFTGAMPYRRARERGVKMIGATA
MLBr_00160|M.leprae_Br4923          GFMRILGPQFLARFFGRIVNTHPALLPAFPGTHGVADALAYGVKVTGATV
MAV_1080|M.avium_104                GFMKILGPQFLSRFYGRVINTHPALLPAFPGAHGVAEALAYGVKVTGCTV
MUL_4713|M.ulcerans_Agy99           GFMRILGPQFLSKFHQRILNTHPALLPAFPGAHGVADALAYGVKVTGCTV
                                     :*:** * *:  .   ::* * ::**** *:     *   ***: *.*.

Mb2988|M.bovis_AF2122/97            HYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRAVLWHCQ
Rv2964|M.tuberculosis_H37Rv         HYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRAVLWHCQ
MMAR_1753|M.marinum_M               HYVTEALDEGPIIEQDVVRVDHNDTVHDLVRVGADVERAVLSRAVLWHCQ
TH_1912|M.thermoresistible__bu      HYVTEELDEGPIIEQDVVRVDHRDTVDDLRRMGADVERVVLSRAVRWHCE
MSMEG_2200|M.smegmatis_MC2_155      HYVTEDLDEGPIIEQDVVRVDHRHTVEDLVRLGADVERLVLSRAVLWHCE
Mflv_5090|M.gilvum_PYR-GCK          HYVTDDLDEGPIIEQDVVRVDHRHSVDDLVRLGADVERAVLSRAVLWHCE
Mvan_1265|M.vanbaalenii_PYR-1       HYVTDDLDEGPIIEQDVVRVDHRHSVDDLVRLGADVERAVLSRAVLWHCE
MAB_1306|M.abscessus_ATCC_1997      HYVTAELDEGPIIEQDVIRVDHTHTVEDLVRLGSDVERLVLSRAVAWHCE
MLBr_00160|M.leprae_Br4923          HLVDAGTDTGPILAQQSVPVLDGDDTAALHERIKVIERRLLVDVVAVIAT
MAV_1080|M.avium_104                HLVDAGTDTGPILAQQSVPVLDGDDEQTLHERIKVTERKLLVDVVAAIAT
MUL_4713|M.ulcerans_Agy99           HLVDAGMDTGPILAQQAIAVLDGDDEATLHERIKVVERKLLVDVVAGIAA
                                    * *    * ***: *: : * . .    * .     ** :*  .*   . 

Mb2988|M.bovis_AF2122/97            DRVIVHHNQTIVF------
Rv2964|M.tuberculosis_H37Rv         DRVIVHHNQTIVF------
MMAR_1753|M.marinum_M               DRVIVHHNQTIVF------
TH_1912|M.thermoresistible__bu      DRVIRYGNQTVVL------
MSMEG_2200|M.smegmatis_MC2_155      DRVIRFGNQTVVF------
Mflv_5090|M.gilvum_PYR-GCK          DRVIRHGNQTICL------
Mvan_1265|M.vanbaalenii_PYR-1       DRVIRHGNQTICL------
MAB_1306|M.abscessus_ATCC_1997      DRVMRHGNVTAIL------
MLBr_00160|M.leprae_Br4923          GGVTLVGRKATIGRKATIE
MAV_1080|M.avium_104                GGLTLVGRKATIG------
MUL_4713|M.ulcerans_Agy99           GGVTVIGRKAMIGRKATIG
                                    . :    . :