For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1781 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 3486821 - 3488203
length: 461

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1781-100% (461)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0132-1e-15861.59% (466) hypothetical protein Mb0132
M. gilvum PYR-GCKMflv_1087-1e-15160.34% (464) hypothetical protein Mflv_1087
M. tuberculosis H37RvRv0127-1e-15761.37% (466) hypothetical protein Rv0127
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0326-1e-16364.01% (464) hypothetical protein MMAR_0326
M. avium 104MAV_5185-1e-16865.95% (464) trehalose synthase-fused maltokinase
M. smegmatis MC2 155MSMEG_6514-1e-17667.32% (459) trehalose synthase-fused maltokinase
M. ulcerans Agy99MUL_4796-1e-16263.79% (464) hypothetical protein MUL_4796
M. vanbaalenii PYR-1Mvan_5735-1e-15762.45% (466) hypothetical protein Mvan_5735

CLUSTAL 2.0.9 multiple sequence alignment


TH_1781|M.thermoresistible__bu      --------MNLPFKDWLPHQRWYAGRSRELVTAEPATVIALSEDMDLVLL
MSMEG_6514|M.smegmatis_MC2_155      --------MSVEFEDWLTQQRWYAGRNRELVSATTAMAVRLRDGLELVLL
Mb0132|M.bovis_AF2122/97            MTRSDTLATKLPWSDWLPRQRWYAGRNRELATVKPGVVVALRHNLDLVLV
Rv0127|M.tuberculosis_H37Rv         MTRSDTLATKLPWSDWLSRQRWYAGRNRELATVKPGVVVALRHNLDLVLV
MMAR_0326|M.marinum_M               MNSPATLAAKLPWSEWLPQQRWYAGRNRELAAAEPGAVVALRDDLDLVLV
MUL_4796|M.ulcerans_Agy99           MNSPATLAAKLPWSEWLPQQRWYAGRNRELAAAEPGAVVALRDDLDLVLV
MAV_5185|M.avium_104                MTEP----AKLPWSDWLPQQRWYAGRNRRLTGAEPSVIVGLRDDLDLVLV
Mflv_1087|M.gilvum_PYR-GCK          --------MTLAFGEWIIHRRWYAGRTRELASAQPAAVTALGDGLDHVLL
Mvan_5735|M.vanbaalenii_PYR-1       --------MTLAFGDWIVHRRWYAGRSRELVSAEPAVVTPLRDDLDHILL
                                             .: : :*: ::******.*.*. . ..    * ..:: :*:

TH_1781|M.thermoresistible__bu      DVDYRDGSAEKYQIIVSWHADGPQGGPDRGHGGGPIEEYSAVATIGSA--
MSMEG_6514|M.smegmatis_MC2_155      QANYADGPDERYQVIV-------------ATGSGPIDEYSVVATIGIA--
Mb0132|M.bovis_AF2122/97            DVTYTDGATERYQVLVGWD-------------FEPASEYGTKAAIGVA--
Rv0127|M.tuberculosis_H37Rv         DVTYTDGATERYQVLVGWD-------------FEPASEYGTKAAIGVA--
MMAR_0326|M.marinum_M               DVSYTDGSAERYQVLVRWD-------------AGPVSEFSTLATIGSA--
MUL_4796|M.ulcerans_Agy99           DVSYTDGSAERYQVLVRWD-------------AGPVSEFSTLATIGSA--
MAV_5185|M.avium_104                DADYADGSRDRYQVLVCWD-------------AAPVSEYSTVATIGAA--
Mflv_1087|M.gilvum_PYR-GCK          DVAYTDGFTERYQILVQWE-------------SAPVDRYGEAALIGTSSG
Mvan_5735|M.vanbaalenii_PYR-1       DVTYTDGTVERYQLVVRWA-------------DSPVAGFGEAATIGTALG
                                    :. * **  ::**::*                  *   :.  * ** :  

TH_1781|M.thermoresistible__bu      --GDRTAYDALYDPAAARHLLELFERSATVGA----VRFDKEPGVTLPLQ
MSMEG_6514|M.smegmatis_MC2_155      --DGQTAYDALYDPDATRYLLSLIDESATVQN----VRFVREPDVELPLD
Mb0132|M.bovis_AF2122/97            --DDRTGFDALYDVAGPQFLLSLIVSSAVCGTSTGEVTFTREPDVELPFA
Rv0127|M.tuberculosis_H37Rv         --DDRTGFDALYDVAGPQFLLSLIVSSAVCGTSTGEVTFTREPDVELPFA
MMAR_0326|M.marinum_M               --DDHTGFDALYDPVAPQVLLSLIDSSAVRSSSDGQVSFAREPDVELPLD
MUL_4796|M.ulcerans_Agy99           --DDHTGFDALYDPVAPQVLLSLIDSSAVRSSSDGQVSFAREPDVELPLD
MAV_5185|M.avium_104                --DDRTGFDALYDDEAPQFLLSLIDSSAVRSASGAEVRFAKEPDAQLPLE
Mflv_1087|M.gilvum_PYR-GCK          PDGTRFAYDALFNPEAASRLLRLINSSETVGE----LTFSREPDVTLPVD
Mvan_5735|M.vanbaalenii_PYR-1       PQGERIAYDALFDPDAARHLLRLVDASATVAD----LRFTREPGATLPLY
                                      . : .:***::  ..  ** *.  * .       : * :**.. **. 

TH_1781|M.thermoresistible__bu      ASPRVSPAEQSNTSVIYEDVHGGEDAVIFKSFRRVTPGVHPDIELNRVLA
MSMEG_6514|M.smegmatis_MC2_155      APPRVFGAEQSNTSVVFG------EDAIFKLFRRITPGVHPDIELNRVLA
Mb0132|M.bovis_AF2122/97            AQPRVCDAEQSNTSVIFDR------RAILKVFRRVSSGINPDIELNRVLT
Rv0127|M.tuberculosis_H37Rv         AQPRVCDAEQSNTSVIFDR------RAILKVFRRVSSGINPDIELNRVLT
MMAR_0326|M.marinum_M               AYPRVSDAEQSNTSVIFDRG----QAAILKVFRRVSSGINPDIELNRVLG
MUL_4796|M.ulcerans_Agy99           AYPRVSDAEQSNTSVIFDRG----QAAILKVFRRVSSGINPDIELNRVLG
MAV_5185|M.avium_104                AMAHVSDAEQSNTSVIFDR------DAIFKVFRRVSSGINPDIELNRVLG
Mflv_1087|M.gilvum_PYR-GCK          APAKVSGAEQSNTSVIFGK------DAMLKVFRRVTPGINPDIELNRVLA
Mvan_5735|M.vanbaalenii_PYR-1       APPKVSSAEQSNTSVIFGK------DAMLKVFRRVTPGINPDIELNRVLA
                                    * .:*  ********::         .::* ***::.*::********* 

TH_1781|M.thermoresistible__bu      RAGNPHVARLMAAYEIEFD-GAP-----YALGMITEFAANSAEGWDMATA
MSMEG_6514|M.smegmatis_MC2_155      RAGNPHVARLLGSFETEWE-GEP-----YALGMVTEFAANSAEGWDMATT
Mb0132|M.bovis_AF2122/97            RAGNPHVARLLGAYQFGRPNRSPTDALAYALGMVTEYEANAAEGWAMATA
Rv0127|M.tuberculosis_H37Rv         RAGNPHVARLLGAYQFGRPNRSPTDALAYALGMVTEYEANAAEGWAMATA
MMAR_0326|M.marinum_M               RAHNPHVARLLGTYEIGIPGEPP--EAACPLGMATAYAANAAEGWAMATA
MUL_4796|M.ulcerans_Agy99           RAHNPHVARLLGTYEIGIPGEPP--EAACPLGMATAYAANAAEGWAMATA
MAV_5185|M.avium_104                RAGNPHVARLLGTYEMAGADGTP--ETAWPLGMVTEFAANAAEGWAMATA
Mflv_1087|M.gilvum_PYR-GCK          RAGNPRVATLLGSFETS----------SCALGMVTAFAANSAEGWDMATA
Mvan_5735|M.vanbaalenii_PYR-1       QAGNRHVARLLGSFETSWAGPGT---DRCALGMVTAFAANSAEGWDMATA
                                    :* * :** *:.:::              .*** * : **:**** ***:

TH_1781|M.thermoresistible__bu      STRDLYAEGDLYADEVGGDFAAESYRLGEAVASVHRSLAEQLGRGTAEFP
MSMEG_6514|M.smegmatis_MC2_155      STRDLFAEGDLYAEEVGGDFAGEAYRLGEAVASVHACLAHELGTEEVPFP
Mb0132|M.bovis_AF2122/97            SVRDLFAEGDLYAHEVGGDFAGESYRLGEAVASVHATLADSLGTAQATFP
Rv0127|M.tuberculosis_H37Rv         SVRDLFAEGDLYAHEVGGDFAGESYRLGEAVASVHATLADSLGTAQATFP
MMAR_0326|M.marinum_M               SVRDLFAEGDLYAHEVGGDFAGESRRLGEAVASVHATLAEQLGTAQATFP
MUL_4796|M.ulcerans_Agy99           SVRDLFAEGDLYAHEVGGDFAGESRRLGEAVASVHATLAEQLGTAQATFP
MAV_5185|M.avium_104                SVRDLFAEGDLYAHEVGGDFAGESYRLGEAVASVHATLAETLGTSQAAFP
Mflv_1087|M.gilvum_PYR-GCK          SVHDLFAN------EVGGDFADESRRLGEAVASVHATLAGALGTSVAEFP
Mvan_5735|M.vanbaalenii_PYR-1       SAREMFAD------VVGSDFADESYRLGNAVASVHATLAEALGTSTEPFP
                                    *.::::*:       **.*** *: ***:******  **  **     **

TH_1781|M.thermoresistible__bu      VEPLLARLAAATETVPALQPYAALIEERYRKLAEQTITVQRIHGDLHLGQ
MSMEG_6514|M.smegmatis_MC2_155      ADVMAQRLAAAVDAVPELREHVPQIEERYHKLADTTMTVQRVHGDLHLGQ
Mb0132|M.bovis_AF2122/97            VDRMLARLSSTVAVVPELREYAPTIEQQFQKLAAEAITVQRVHGDLHLGQ
Rv0127|M.tuberculosis_H37Rv         VDRMLARLSSTVAVVPELREYAPTIEQQFQKLAAEAITVQRVHGDLHLGQ
MMAR_0326|M.marinum_M               VDHVLARLSSTAAAVPELQQYAGTIEERFVKLVDETISVQRVHGDLHLGQ
MUL_4796|M.ulcerans_Agy99           VDHVLARLSSTAAAVPELQQYAGTIEERFVKLVDETISVQRVHGDLHLGQ
MAV_5185|M.avium_104                VDNVLARLSSTAALVPELTEYAATIEERFAKLATETITVQRVHGDLHLGQ
Mflv_1087|M.gilvum_PYR-GCK          IDTVLDRLRVATQAAPELAPYAPRIEERFRRLAERPIQVHRVHGDLHLGQ
Mvan_5735|M.vanbaalenii_PYR-1       VDTVLARLQSAARSAPELAGRAAAVEERYRRLDGRAITVQRVHGDLHLGQ
                                     : :  **  :.  .* *   .  :*::: :*   .: *:*:********

TH_1781|M.thermoresistible__bu      VLRTPERWLLIDFEGEPGYPLSERRRPDSPLRDVAGMLRSYEYAAYHRLA
MSMEG_6514|M.smegmatis_MC2_155      VLRTPKGWLLIDFEGEPGQPLDERRRPDTPVRDVAGILRSFEYAAHQRLV
Mb0132|M.bovis_AF2122/97            VLRTPESWLLIDFEGEPGQPLDERRAPDSPLRDVAGVLRSFEYAAYGPLV
Rv0127|M.tuberculosis_H37Rv         VLRTPESWLLIDFEGEPGQPLDERRAPDSPLRDVAGVLRSFEYAAYGPLV
MMAR_0326|M.marinum_M               VLRTPESWVLIDFEGEPGQPLRERRAPDSPLRDVAGVLRSFEYAAYGPLV
MUL_4796|M.ulcerans_Agy99           VLRTPESWVLIDFEGESGQPLRERRAPDSPLRDVAGVLRSFEYAAYGPLV
MAV_5185|M.avium_104                VLRTPESWLLIDFEGEPGQPLEERRAPDSPLRDVAGVLRSFEYAAYGPLV
Mflv_1087|M.gilvum_PYR-GCK          VLRTPESWLLIDFEGEPGQPLEDRRRPDSPLRDVAGVLRSFEYAAYQQVV
Mvan_5735|M.vanbaalenii_PYR-1       VLRTPDDWLLIDFEGEPGQPLDERRRPDSPLRDVAGVLRSFEYAAYQKLV
                                    *****. *:*******.* ** :** **:*:*****:***:****:  :.

TH_1781|M.thermoresistible__bu      EQGGDDLQHDKQLAARAREWVDRNTAAFCDGYAAVAGDDPRHHAELLAAY
MSMEG_6514|M.smegmatis_MC2_155      DQAGDDDDRARQLAARAREWVTRNCASFCDGYAAEAGTDPRDSADLLAAY
Mb0132|M.bovis_AF2122/97            DQAT-----DKQLAARAREWVERNRAAFCDGYAVASGIDPRDSALLLGAY
Rv0127|M.tuberculosis_H37Rv         DQAT-----DKQLAARAREWVERNRAAFCDGYAVASGIDPRDSALLLGAY
MMAR_0326|M.marinum_M               DHAD-----DKQLAARAREWITRNRTAFCEGYAAASGNDPRDSELLLAAY
MUL_4796|M.ulcerans_Agy99           DHAD-----DKQLAARAREWITRNRTAFCEGYAAASGNDPRDSELLLAAY
MAV_5185|M.avium_104                EQGSQN--TDKQLAARAREWVERNRTAFCDGYAAASGIDPRDSAPLLAAY
Mflv_1087|M.gilvum_PYR-GCK          TGG-----GDAQMAERARSWVDRNVDAFCAGYAAVAGEDPRASGDVLAAY
Mvan_5735|M.vanbaalenii_PYR-1       ELAPEQ-DADGRLADRARNWVDRNSAAFCAGYAAVAGDDPRRDGDVLAAY
                                      .        ::* ***.*: **  :** ***. :* ***    :*.**

TH_1781|M.thermoresistible__bu      ELDKAVYEAGYEARHRPSWVPIPLESIARLIS-
MSMEG_6514|M.smegmatis_MC2_155      ELDKAVYEAAYEARHRPSWLPIPLGSIARLLE-
Mb0132|M.bovis_AF2122/97            ELDKAVYETGYETRHRPGWLPIPLRSIARLTAS
Rv0127|M.tuberculosis_H37Rv         ELDKAVYETGYETRHRPGWLPIPLRSIARLTAS
MMAR_0326|M.marinum_M               ELDKAVYEAGYESRHRPGWLPIPLRSIARLTAT
MUL_4796|M.ulcerans_Agy99           ELDKAVYEAGYESRHRPGWLPIPLRSIARLTAT
MAV_5185|M.avium_104                ELDKAVYEAGYEARHRPGWLPIPLRSIARLTAA
Mflv_1087|M.gilvum_PYR-GCK          ELDKAVYEAAYEARFRPSWLPIPMRSIQRLVS-
Mvan_5735|M.vanbaalenii_PYR-1       ELDKAVYEAAYEARFRPSWLPIPMRSIDRILG-
                                    ********:.**:*.**.*:***: ** *: