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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1736 | - | 100% (432) | MCE-FAMILY PROTEIN MCE4D | |
| M. thermoresistible (build 8) | TH_1934 | - | e-154 | 60.52% (423) | MCE-FAMILY PROTEIN MCE4D |
| M. thermoresistible (build 8) | TH_4516 | - | 4e-78 | 38.94% (434) | PUTATIVE virulence factor mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3526c | mce4D | 1e-129 | 53.70% (419) | MCE-family protein MCE4D |
| M. gilvum PYR-GCK | Mflv_1559 | - | 1e-155 | 60.80% (426) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv3496c | mce4D | 1e-129 | 53.70% (419) | MCE-family protein MCE4D |
| M. leprae Br4923 | MLBr_02592 | mce1D | 7e-62 | 31.45% (442) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4150c | - | 1e-126 | 54.13% (412) | MCE-family protein |
| M. marinum M | MMAR_4984 | mce4D | 1e-131 | 55.29% (416) | MCE-family protein Mce4D |
| M. avium 104 | MAV_0660 | - | 1e-135 | 55.85% (410) | virulence factor mce family protein |
| M. smegmatis MC2 155 | MSMEG_5897 | - | 1e-153 | 61.06% (416) | virulence factor mce family protein |
| M. ulcerans Agy99 | MUL_4059 | mce4D | 1e-131 | 55.05% (416) | MCE-family protein Mce4D |
| M. vanbaalenii PYR-1 | Mvan_5199 | - | 1e-157 | 61.14% (422) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1559|M.gilvum_PYR-GCK -----MTQENSVT-RSRWLRPVLICVLVAVLAIG-AYLVWPSRTG-QKVT
Mvan_5199|M.vanbaalenii_PYR-1 -----------MK-RSRWLRTALVGVLVATLAIG-AYLVWPNRAG-HKVT
MSMEG_5897|M.smegmatis_MC2_155 -----MTHSNSTSNRGRWVRLALAALLLVTLGVG-IYQVWPSRGG-LKLT
TH_1736|M.thermoresistible__bu ---------MSAPITRRRARAAIAGLLAVLLAAG-VIAVWPRPAQ-RTVT
Mb3526c|M.bovis_AF2122/97 -----MMGRVAMLTGSRGLRYATVIALVAALVGG-VYVLSSTGNK-RTIV
Rv3496c|M.tuberculosis_H37Rv -----MMGRVAMLTGSRGLRYATVIALVAALVGG-VYVLSSTGNK-RTIV
MMAR_4984|M.marinum_M -----MMK---QRLSSRGMRTVTIVALVAALVGG-LYVLFSGGESGRKVV
MUL_4059|M.ulcerans_Agy99 -----MMK---QRLSSRGMRTVTIVALVAALVGG-LYVLFSGGESGRKVV
MAV_0660|M.avium_104 -----MMQR---LAGSRGLRYTTIIALVAVLVGG-VYVLTSQAKT-RKIV
MAB_4150c|M.abscessus_ATCC_199 -----------MTTSKTWLKRGAFAMLSVALVGGLLYWVWPSRGT-YKIV
MLBr_02592|M.leprae_Br4923 MSTIFDVRKLKLLRLSRAPVIVGSLVVVLALVVGFVGWRLYQKLTNNTVV
: * * .:.
Mflv_1559|M.gilvum_PYR-GCK AYFTSAVGLYPGDDVRVVGVPVGTIDAIDPRANDVKITMTIDSDVKLPAE
Mvan_5199|M.vanbaalenii_PYR-1 AYFTSAVGLYPGDDVRVVGVPVGTIDSIEPRAGDVKITMTIDGDVKVPAE
MSMEG_5897|M.smegmatis_MC2_155 AYFTNAVGLYPGDQVRVVGVPVGTIDSIEPRPSDVKIEMTLDRGVKVPAD
TH_1736|M.thermoresistible__bu GLFASAVGLYVGDEVKVAGVPVGRVTAIEPGPAHTTVSMRVRADIPIPAD
Mb3526c|M.bovis_AF2122/97 GYFTSAVGLYPGDQVRVLGVPVGEIDMIEPRSSDVKITMSVSKDVKVPVD
Rv3496c|M.tuberculosis_H37Rv GYFTSAVGLYPGDQVRVLGVPVGEIDMIEPRSSDVKITMSVSKDVKVPVD
MMAR_4984|M.marinum_M AYFTSAVGIYPGDEVRILGVPVGRIDSIEPRPADVKITMSVSNDVKIPRD
MUL_4059|M.ulcerans_Agy99 AYFTSAVGIYPGDEVRILGVPVGRIDSIEPRPADVKITMSVSNDVKIPRD
MAV_0660|M.avium_104 GYFTSAVGLYPGDQVRVLGVPVGTIDTIDPRPTDVKITMSVSQDVKVPKD
MAB_4150c|M.abscessus_ATCC_199 GHFASAVGLYPGDDVRILGVKAGRISAVEPREGDVKVTMEMPDKFKVPEG
MLBr_02592|M.leprae_Br4923 VYFPAATALYTGDKVQIMGLRVGSIDSIVPAGDKMKVTFHYQNKYKVPAN
*. *..:* **.*:: *: .* : : * . .: : :*
Mflv_1559|M.gilvum_PYR-GCK AKALVISPNLVSARFIQLTPAYTGGAVLADGAEIGLDRTAVPVEWDEVKE
Mvan_5199|M.vanbaalenii_PYR-1 AKALVIAPNLVSARFIQLAPAYTGGTVMADGAEIGLDRTAVPVEWDEVKE
MSMEG_5897|M.smegmatis_MC2_155 AKALIIAPNLVAARFIQLTPAYTEGDEMADGTSIGLDRTAVPVEWDQVKE
TH_1736|M.thermoresistible__bu ASALIVAPNLVSARFVEFAPVYDGGPILADDAVIGPDRTAVPIEWDQVKD
Mb3526c|M.bovis_AF2122/97 VQAVIMSPNLVAARFIQLTPVYTGGAVLPDNGRIDLDRTAVPVEWDEVKE
Rv3496c|M.tuberculosis_H37Rv VQAVIMSPNLVAARFIQLTPVYTGGAVLPDNGRIDLDRTAVPVEWDEVKE
MMAR_4984|M.marinum_M AQALIVSPNLVAARFIQLTPVYTGGAVLPDGASIDLSRTAIPVEWDEVKE
MUL_4059|M.ulcerans_Agy99 AQALIVSPNLVAARFIQLTPVYTGGAVVPDGASIDLSRTAIPVEWDEVKE
MAV_0660|M.avium_104 AKAIIMSPNLVAARFIQLTPAYTGGPVLADGASIGLDRTAVPVEWDEVKQ
MAB_4150c|M.abscessus_ATCC_199 AQAIIMAPNLVTARFVQLTPAYTDGKALQDGASLGLDKTAVPIEWDEVKT
MLBr_02592|M.leprae_Br4923 ASAVILNPTLVASRSIQLEPPYKGGPALGDNAVIPLERTQVPVEWDELRD
..*::: *.**::* ::: * * * : *. : .:* :*:***:::
Mflv_1559|M.gilvum_PYR-GCK QLTQLSTQLGPNEDSVRGPLTDVVNQAADTFDGNGDTFRSAVRELSQTAG
Mvan_5199|M.vanbaalenii_PYR-1 QLTQLSTQLGPHEGSVQGPLTDVVNQAADTFDGNGDTFRRAVRELSQTAG
MSMEG_5897|M.smegmatis_MC2_155 QLTQLSSQLGPQEGSVQGPLAQVVNQAADTFDGNGDSFRNALRELSQTAG
TH_1736|M.thermoresistible__bu ELTRLAAQLGPQPGAVQGPLSQVINQAADTFDGAGRSFRDAVRELSQAAG
Mb3526c|M.bovis_AF2122/97 GLTRLAADLSPAAGELQGPLGAAINQAADTLDGNGDSLHNALRELAQVAG
Rv3496c|M.tuberculosis_H37Rv GLTRLAADLSPAAGELQGPLGAAINQAADTLDGNGDSLHNALRELAQVAG
MMAR_4984|M.marinum_M SLTQLAVQLSPAAGELQGPLGAAINQAADTLNGNGDSFHNALRELSQVAG
MUL_4059|M.ulcerans_Agy99 SLTQLAVQLSPAAGELQGPLGAAINQAADTLNGNGDSFHNALRELSQVAG
MAV_0660|M.avium_104 SLTQLAVQLGPTAGSMQGPLGAAINQAADTFDGKGESFHSALRELSQAAG
MAB_4150c|M.abscessus_ATCC_199 ELAKLSDSLGPQ-GQSKGPVSDFINQAATTFDGNGDSFRNAVRELSQAAG
MLBr_02592|M.leprae_Br4923 SITKIISKLGPTKEQPKGPFGDVIESFADGLAGKGKQINATLDSLSRALT
:::: .*.* :**. ::. * : * * :. :: .*::.
Mflv_1559|M.gilvum_PYR-GCK RLGDSRADLFGTIRNLQILVDALSRSNEQIVQFSNHVASVSQVLADATTD
Mvan_5199|M.vanbaalenii_PYR-1 RLGDSRTDLFGTIRNLQILVDALSNSNEQIVQFSNHVASVSQVLADATTD
MSMEG_5897|M.smegmatis_MC2_155 RLGDSRTDLFGTVRNLQILVDALSNSNEQIVQFTNHVASVSQVLADSANG
TH_1736|M.thermoresistible__bu RLGDSRADLIGTVKNLSVVVDALAASNEQIVAFTSHVASVSQVFANSSQD
Mb3526c|M.bovis_AF2122/97 RLGDSRGDIFGTVKNLQVLVDALSESDEQIVQFAGHVASVSQVLADSSAN
Rv3496c|M.tuberculosis_H37Rv RLGDSRGDIFGTVKNLQVLVDALSESDEQIVQFAGHVASVSQVLADSSAN
MMAR_4984|M.marinum_M RLGDSRNDIFSTVKNLQVLVDALSQSNEQIVQFAGHVASVSQVLADSSRN
MUL_4059|M.ulcerans_Agy99 RLGDSRNDIFSTVKNLQVLVDALSQSNEQIVQFAGHVASVSQVLADSSRN
MAV_0660|M.avium_104 RLGDSRGDIFGTVKNLQILVNALSSSNEQIVQFAGNVASVSQVLADSSRH
MAB_4150c|M.abscessus_ATCC_199 RLGDSRTDLFGTIKNLQTLVDALANSNEQIVQFSTHLASVSKVLAASTEN
MLBr_02592|M.leprae_Br4923 ALNEGRGDFFAVLRSLALFVNALHTDDQQFVALNQNLADFTTRLAHSDTD
*.:.* *::..::.* .*:** .::*:* : ::*..: :* :
Mflv_1559|M.gilvum_PYR-GCK LDITLGTLNQALTDVRGFLGESNEALIGQVNRLTDFTNLLTEHS--DDIE
Mvan_5199|M.vanbaalenii_PYR-1 LDVTLGTLNQALTDVRGFLGESNEALIGQVNKLTDFTNILTAQS--DDIE
MSMEG_5897|M.smegmatis_MC2_155 LDSTLDTLNQALSDVRGFLNESNDSLIAQVGKLADFTQILTDHS--EDIE
TH_1736|M.thermoresistible__bu IDQALGALNTALSDVRDLLRDNDDALRGQIDRLTEFTSLLTERS--DDIE
Mb3526c|M.bovis_AF2122/97 LDQTLGTLNQALSDIRGFLRENNSTLIETVNQLNDFAQTLSDQS--ENIE
Rv3496c|M.tuberculosis_H37Rv LDQTLGTLNQALSDIRGFLRENNSTLIETVNQLNDFAQTLSDQS--ENIE
MMAR_4984|M.marinum_M LDNTLGTLNQALSDIKGFLRENNSTLIETVNQLGDLTQTLSDQS--DNIE
MUL_4059|M.ulcerans_Agy99 LDNTLGTLNQALSDIKGFLRENNSTLIETVNQLGDLTQTLSDQS--DNIE
MAV_0660|M.avium_104 LDTTLGTLNKALSDIRGFLHENNSTIVDTVNNLNDFAKTLSDQS--DNIE
MAB_4150c|M.abscessus_ATCC_199 LGATLGALNQALTDVRGFLGDTNSALIDQVNKLSDFVKIFSDQS--DDLE
MLBr_02592|M.leprae_Br4923 LSSALQQFNSMLSTVQSFLVKNREVLAADVNNLATVNNTVVQPEPLNGVE
:. :* :* *: ::.:* .. . : :..* . . . . :.:*
Mflv_1559|M.gilvum_PYR-GCK QILHITPNGLSNFYNIYNPAQGTVGGLLTLPNFANPVQFICGGTFDAAAT
Mvan_5199|M.vanbaalenii_PYR-1 QILHITPNGLSNFYNIYNPAQGTVGGLLTLPNFGNPVQFICGGTFDAAAT
MSMEG_5897|M.smegmatis_MC2_155 QLLHVTPNGLANFYNIYNPAQGTVGGLLSLPNFANPVQFICGGTFDTGAN
TH_1736|M.thermoresistible__bu QVLHLAPHALANFYNIYTPAQASVAGIVTLPNFGNPVQLMCAGMFETAKT
Mb3526c|M.bovis_AF2122/97 QVLHVAGPGITNFYNIYDPAQGTLNGLLSIPNFANPVQFICGGSFDTAAG
Rv3496c|M.tuberculosis_H37Rv QVLHVAGPGITNFYNIYDPAQGTLNGLLSIPNFANPVQFICGGSFDTAAG
MMAR_4984|M.marinum_M QVLHVAGPGITNFYNIYDPAQGTLNGLLSIPNFANPVQFICGGSFDTAAG
MUL_4059|M.ulcerans_Agy99 QVLHVAGPGITNFYNIYDPAQGTLNGLLSIPNFANPVQFICGGSFDTAAG
MAV_0660|M.avium_104 QVLHVAGPGIANFYNIYDPAQGTLNGLLSIPEFANPVQFICGGSFETAGG
MAB_4150c|M.abscessus_ATCC_199 QILHVAPNGLANFYNIYNPAAGTLNGMLSIPNLANPVQFICGGVFETGTK
MLBr_02592|M.leprae_Br4923 TFLHVAPTAAANMNQLYHPAHGSVVGVPTITNFANPMQFICSAIQAGSRL
.**:: . :*: ::* ** .:: *: ::.::.**:*::*.. .
Mflv_1559|M.gilvum_PYR-GCK ---PDNYKRAEICRQRMGPVFKRITMNYPPLLFHPINSITAYKGQIIYDT
Mvan_5199|M.vanbaalenii_PYR-1 ---TDNYKRAEICRQRMGPVFKRIAMNYPPLLFHPINSITAYKGQIIYDT
MSMEG_5897|M.smegmatis_MC2_155 ---PENYKRAEICRQRMGPVLKRITMNYPPVLFHPINSITAYKGQIIYDT
TH_1736|M.thermoresistible__bu ---PESYNRAEICRQRMAPVIKRLQMNYPPFLMHPINSITAYKGQIIYDT
Mb3526c|M.bovis_AF2122/97 PSAPDYYRRAEICRERLGPVLRRLTVNYPPIMFHPLNTITAYKGQIIYDT
Rv3496c|M.tuberculosis_H37Rv PSAPDYYRRAEICRERLGPVLRRLTVNYPPIMFHPLNTITAYKGQIIYDT
MMAR_4984|M.marinum_M KSAPDYYRRAELCRERLGPVLRRLTANYPPFLFHPLNTITAYKGQIIYDT
MUL_4059|M.ulcerans_Agy99 KSAPDYYRRAELCRERLGPVLRRLTANYPPFLFHPLNTITAYKGQIIYDT
MAV_0660|M.avium_104 PRAPDYYKRAELCRERLGPVLRRLTVNYPPLMFHPLNTITAYKGQIIYDT
MAB_4150c|M.abscessus_ATCC_199 ---TEYLKRAEICRERMGPVLRRATFNYAPILLHPINQISAYKGQIIYDT
MLBr_02592|M.leprae_Br4923 G----YQESAELCAQYLSPVLDAIKFNYFPFGLNLFSTAEVLPKEVAYSE
. **:* : :.**: ** *. :: :. . :: *.
Mflv_1559|M.gilvum_PYR-GCK PATEAKA-------------ETPVPY----LQWQNAPGVTP-------PK
Mvan_5199|M.vanbaalenii_PYR-1 PATEAKA-------------ETPVPY----LQWQNAPGVTP-------PQ
MSMEG_5897|M.smegmatis_MC2_155 PETQAKA-------------ETPVPY----LQWQNAPGVTP-------PQ
TH_1736|M.thermoresistible__bu PETQAKA-------------QTPISH----LQWQPLPGVTP-------PS
Mb3526c|M.bovis_AF2122/97 PATEAKS-------------ETPVPE----LTWVPAGGG---------AP
Rv3496c|M.tuberculosis_H37Rv PATEAKS-------------ETPVPE----LTWVPAGGG---------AP
MMAR_4984|M.marinum_M PATQAKA-------------ETPVPE----LTWIPAHPAPQ-------PA
MUL_4059|M.ulcerans_Agy99 PATQAKA-------------ETPVPE----LTWIPAHPAPQ-------PA
MAV_0660|M.avium_104 PETQAKS-------------ATPVPQ----LTWIPAKGAQTP------PA
MAB_4150c|M.abscessus_ATCC_199 PETEAKS-------------QAPRED----LVWVRPNGAPP-------PP
MLBr_02592|M.leprae_Br4923 ARLQPPSGYKDTTVPGIWVPDTPLSHRNTQPGWIVAPGMQGQQVGPITAA
. :. : :* * .
Mflv_1559|M.gilvum_PYR-GCK VAPDADLTSLLVPAEG----------------------------------
Mvan_5199|M.vanbaalenii_PYR-1 IAPDADLTSLLVPAEG----------------------------------
MSMEG_5897|M.smegmatis_MC2_155 IPADANLSDFIVPPD-----------------------------------
TH_1736|M.thermoresistible__bu VPPDTDLTELMVPEPQ----------------------------------
Mb3526c|M.bovis_AF2122/97 VGNPADLQSLLVPPAP----------------------GPAP--------
Rv3496c|M.tuberculosis_H37Rv VGNPADLQSLLVPPAP----------------------GPAP--------
MMAR_4984|M.marinum_M PGNTTDLQSLFVPQAP----------------------GPAPGSPPGYGP
MUL_4059|M.ulcerans_Agy99 PGNTTDLQSLFVPQAP----------------------GPTPGSPPGYGP
MAV_0660|M.avium_104 VQNPADLQALLVPTAPQ--------------------SGPAPAGG-----
MAB_4150c|M.abscessus_ATCC_199 KPSPQDLSALMLGPDEV--------------------NAPPP--------
MLBr_02592|M.leprae_Br4923 LMTPDSLAELMGGPDIEPIQSNLQTPPGPPTAYDEHPVPPPIGLQASVPI
.* ::
Mflv_1559|M.gilvum_PYR-GCK ---AEASTSHAGGPETGPAPAAPAAPGPAEAGR--
Mvan_5199|M.vanbaalenii_PYR-1 ---PEASTSHAGGPETGPAPAAPVAPGPAEAGR--
MSMEG_5897|M.smegmatis_MC2_155 ---PATATEHGG-----PAAAPGPAPAPGGAGG--
TH_1736|M.thermoresistible__bu ---KESGR---------------------------
Mb3526c|M.bovis_AF2122/97 ---APPAPG--AG--------------PGEHGGGG
Rv3496c|M.tuberculosis_H37Rv ---APPAPG--AG--------------PGEHGGGG
MMAR_4984|M.marinum_M APGPPPAPAP-AGPDAGLSSPAPGAPLPAEQGAGG
MUL_4059|M.ulcerans_Agy99 APGPPPAPAP-AGPDAGLSSPAPGAPLPAEQGAGG
MAV_0660|M.avium_104 APAPGPAPGSAFGPRPGPPPGQAPGGLGADLGGGG
MAB_4150c|M.abscessus_ATCC_199 -PGTEVRPAEPGPVPPGFPVTADDAPPPAIPGAPR
MLBr_02592|M.leprae_Br4923 PSPRPDVVPGPVAPTPSPAANVGDPPLPAELGAGQ