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M. thermoresistible (build 8) TH_1399 (gcpE)

annotation: PROBABLE GCPE PROTEIN
coordinates: 2641593 - 2642777
length: 395

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1399gcpE-100% (395)PROBABLE GCPE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2893cispG0.088.52% (392) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
M. gilvum PYR-GCKMflv_4081ispG0.089.26% (391) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
M. tuberculosis H37RvRv2868cispG0.088.78% (392) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
M. leprae Br4923MLBr_01581ispG0.085.20% (392) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
M. abscessus ATCC 19977MAB_3169cispG0.086.51% (393) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
M. marinum MMMAR_1838ispG0.090.00% (390) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, IspG
M. avium 104MAV_3725ispG0.091.83% (367) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
M. smegmatis MC2 155MSMEG_2580ispG0.088.32% (394) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
M. ulcerans Agy99MUL_2087ispG0.091.78% (365) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
M. vanbaalenii PYR-1Mvan_2262ispG0.090.15% (396) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_01581|M.leprae_Br4923          -MN---MRLGMPEA----PAPGLAPRRITRQLMVGNVGVGSDHQISVQSM
MAV_3725|M.avium_104                --------------------------------MVRDVGVGSDYPISVQSM
Mb2893c|M.bovis_AF2122/97           -MT---VGLGMPQP----PAPTLAPRRATRQLMVGNVGVGSDHPVSVQSM
Rv2868c|M.tuberculosis_H37Rv        -MT---VGLGMPQP----PAPTLAPRRATRQLMVGNVGVGSDHPVSVQSM
MMAR_1838|M.marinum_M               -MT---TGLGIPQP----PAPTLSPRRTTRQLMVRDVGVGSDYPVSVQSM
MUL_2087|M.ulcerans_Agy99           --------------------------------MVRDVGVGSDYPVSVQSM
TH_1399|M.thermoresistible__bu      MTS---IGLGMPAVGSGGPAPVLAPRRKTRQLMVCDVGVGSDHPISVQSM
Mflv_4081|M.gilvum_PYR-GCK          MTSTAGVGLGMPAPP----PPVLAPRRKTRQLMVGDVGVGSDHPIAVQSM
Mvan_2262|M.vanbaalenii_PYR-1       MTS---IGLGIPAPP----APVLAPRRKTRQLMVRDVGVGSDHPISVQSM
MSMEG_2580|M.smegmatis_MC2_155      MTS---IGLGMPAPP----APTLAPRRKTRQLNVGGVGIGSEHPIAVQSM
MAB_3169c|M.abscessus_ATCC_199      MMT----GLGMPSLPGA-PPPTLAPRRQTRQLMVGSVGVGSDSPVSVQSM
                                                                     * .**:**:  ::****

MLBr_01581|M.leprae_Br4923          CITKTHDVNATLQQIAELTTAGCDIVRVACPRQEDADALAEIARHSKIPV
MAV_3725|M.avium_104                CTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPV
Mb2893c|M.bovis_AF2122/97           CTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPV
Rv2868c|M.tuberculosis_H37Rv        CTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPV
MMAR_1838|M.marinum_M               CTTKTHDVNATLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPV
MUL_2087|M.ulcerans_Agy99           CTTKTHDVNATLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPV
TH_1399|M.thermoresistible__bu      CTTKTHDVNATLQQIAELTAAGCDIVRVACPRQEDADALPAIAAKSKIPV
Mflv_4081|M.gilvum_PYR-GCK          CTTKTHDINATLQQIAELTASGCDIVRVACPRQEDADALPAIAKKANIPV
Mvan_2262|M.vanbaalenii_PYR-1       CTTKTHDINATLQQIAELTASGCDIVRVACPRQEDADALPIIAKKSKIPV
MSMEG_2580|M.smegmatis_MC2_155      CTTKTHDVNSTLQQIAELTASGCDIVRVACPRQEDADALAEIARHSQIPV
MAB_3169c|M.abscessus_ATCC_199      CTTKTHDVNSTLQQIAELTASGCDIVRVACPRQEDADALAEIARKSKIPV
                                    * *****:*:*********::******************. ** :::***

MLBr_01581|M.leprae_Br4923          IVDIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAAAAGIPI
MAV_3725|M.avium_104                IADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAAAAGIPI
Mb2893c|M.bovis_AF2122/97           VADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPI
Rv2868c|M.tuberculosis_H37Rv        VADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPI
MMAR_1838|M.marinum_M               IADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPI
MUL_2087|M.ulcerans_Agy99           AADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPI
TH_1399|M.thermoresistible__bu      IADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVKEVAKAAGDAGIPI
Mflv_4081|M.gilvum_PYR-GCK          IADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVKEVAKAAGDAGIPI
Mvan_2262|M.vanbaalenii_PYR-1       IADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVAEVAKAAGDAGIPI
MSMEG_2580|M.smegmatis_MC2_155      IADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVKEVAKAAGDAGIPI
MAB_3169c|M.abscessus_ATCC_199      IADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVKEVAKAAGDAGIPI
                                     .******:*************************** ******. *****

MLBr_01581|M.leprae_Br4923          RIGVNAGSLDKRFMDKYGKATSEALVESALWEASLFEEHGFGNIKISVKH
MAV_3725|M.avium_104                RIGVNAGSLDKRFMAKYGKATPEALVESALWEASLFEEHGFSDIKISVKH
Mb2893c|M.bovis_AF2122/97           RIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDIKISVKH
Rv2868c|M.tuberculosis_H37Rv        RIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDIKISVKH
MMAR_1838|M.marinum_M               RIGVNAGSLDKRFMQKYGKATPEALVESALWEASLFEEHGFGNIKISVKH
MUL_2087|M.ulcerans_Agy99           RIGVNAGSLDKRFMQKYGKATPEALVESALWEASLFEEHGFGNIKISVKH
TH_1399|M.thermoresistible__bu      RIGVNAGSLDKRFMQKYGKATPEALVESALWEASLFEEHGFGDIKISVKH
Mflv_4081|M.gilvum_PYR-GCK          RIGVNAGSLDPRILKKYGKATPEALVESAMWEASLFEEHGFGDIKISVKH
Mvan_2262|M.vanbaalenii_PYR-1       RIGVNAGSLDKRFLEKYGKATPEALVESALWEASLFEEHGFGNIKISVKH
MSMEG_2580|M.smegmatis_MC2_155      RIGVNAGSLDKRFLEKYGKATPEALVESALWEASLFEEHGFGDIKISVKH
MAB_3169c|M.abscessus_ATCC_199      RIGVNAGSLDPRILGKYGKATPEALVESALWEAGLFEEHGFGDIKISVKH
                                    ********** *:: ******.*******:***.*******.:*******

MLBr_01581|M.leprae_Br4923          HDPVVMVAAYEQLAAQCDYPLHLGVTEAGPVFQGTVKSAVAFGALLSKGI
MAV_3725|M.avium_104                NDPVVMVAAYEQLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI
Mb2893c|M.bovis_AF2122/97           NDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI
Rv2868c|M.tuberculosis_H37Rv        NDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI
MMAR_1838|M.marinum_M               NDPVIMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI
MUL_2087|M.ulcerans_Agy99           NDPVIMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI
TH_1399|M.thermoresistible__bu      SDPVVMVQAYEMLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI
Mflv_4081|M.gilvum_PYR-GCK          NDPVIMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKGI
Mvan_2262|M.vanbaalenii_PYR-1       NDPVVMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKGI
MSMEG_2580|M.smegmatis_MC2_155      NDPVIMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKGI
MAB_3169c|M.abscessus_ATCC_199      NDPVIMVAAYELLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKGI
                                     ***:** *** ** :**************.****:***********:**

MLBr_01581|M.leprae_Br4923          GDTIRVSLSAPPVEEIKVGNQILESLNLRPRSHEIVSCPSCGRAQVDVYK
MAV_3725|M.avium_104                GDTIRVSLSAPPVEEVKVGIQILESLNLRPRSLEIVSCPSCGRAQVDVYT
Mb2893c|M.bovis_AF2122/97           GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYT
Rv2868c|M.tuberculosis_H37Rv        GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYT
MMAR_1838|M.marinum_M               GDTIRVSLSAPPVEEVKVGNQILESLNLRPRSLEIVSCPSCGRAQVDVYT
MUL_2087|M.ulcerans_Agy99           GDTIRVSLSAPPVEEVKVGNQILESLNLRPRSLEIVSCPSCGRAQVDVYT
TH_1399|M.thermoresistible__bu      GDTIRVSLSAPPVEEVKVGVQILESLNLRPRGLEIVSCPSCGRAQVDVYT
Mflv_4081|M.gilvum_PYR-GCK          GDTIRVSLSAPPAEEVKVGNQILESLNLRPRGLEIVSCPSCGRAQVDVYT
Mvan_2262|M.vanbaalenii_PYR-1       GDTIRVSLSAPPAEEVKVGNQILESLNLRPRGLEIVSCPSCGRAQVDVYT
MSMEG_2580|M.smegmatis_MC2_155      GDTIRVSLSAPPAEEVKVGNQILESLNLRPRGLEIVSCPSCGRAQVDVYT
MAB_3169c|M.abscessus_ATCC_199      GDTIRVSLSAPPAEEVKVGNQILESLNLRPRSLEIVSCPSCGRAQVDVYT
                                    ************.**:*** *:*********. ****************.

MLBr_01581|M.leprae_Br4923          LANEVSAGLDGLEVPLRIAVMGCVVNGPGEARDADLGVASGNGKGQIFVK
MAV_3725|M.avium_104                LANEVSAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVR
Mb2893c|M.bovis_AF2122/97           LANEVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVR
Rv2868c|M.tuberculosis_H37Rv        LANEVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVR
MMAR_1838|M.marinum_M               LANEVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVR
MUL_2087|M.ulcerans_Agy99           LANEVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVR
TH_1399|M.thermoresistible__bu      LANEVTAGLEGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVK
Mflv_4081|M.gilvum_PYR-GCK          LANEVTAGLEGLEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVK
Mvan_2262|M.vanbaalenii_PYR-1       LANEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVK
MSMEG_2580|M.smegmatis_MC2_155      LANAVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVK
MAB_3169c|M.abscessus_ATCC_199      LANAVSAGLEGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVK
                                    *** *:***:*::****:**************:****************:

MLBr_01581|M.leprae_Br4923          GEVIKTVPEAQIVETLIEEAMRLVSEMGTEKGSDHCSETTRSGSPVVTVN
MAV_3725|M.avium_104                GEVIKTVPESQIVETLIEEAMRIAAQMNSEGGP----EATSSGSPVVTVS
Mb2893c|M.bovis_AF2122/97           GEVIKTVPEAQIVETLIEEAMRLAAEMGEQAPG-----ATPSGSPIVTVS
Rv2868c|M.tuberculosis_H37Rv        GEVIKTVPEAQIVETLIEEAMRLAAEMGEQDPG-----ATPSGSPIVTVS
MMAR_1838|M.marinum_M               GEVIKTVPEAQIVETLIEEAMRIAAEMGTEDPG-----TTSSGTPIVTVS
MUL_2087|M.ulcerans_Agy99           GEVIKTVPEAQIVETLIEEAMRIAAEMGTEDPG-----TTSSGAPIVTVS
TH_1399|M.thermoresistible__bu      GEVIKTVPESQIVETLIEEAMRIAAEMGSGDGE---SGPESSGSPIVTVS
Mflv_4081|M.gilvum_PYR-GCK          GEVIKTVPEALIVETLIEEAMRLAADMDTTP----GSEEA-SGSPVVTVS
Mvan_2262|M.vanbaalenii_PYR-1       GEVIKTVPEAQIVETLIEEALRLADEMGEAPGDAQGSEGA-TGSPIVTVS
MSMEG_2580|M.smegmatis_MC2_155      GEVIKTVPEAQIVETLIEEAMRLAEEIGTAR----GSDDA-SGSPVVTVS
MAB_3169c|M.abscessus_ATCC_199      GEVIKTVPEALIVETLIDEAMRLAEQMGLENGAGIGSDGTPTGQPVVTVS
                                    *********: ******:**:*:. ::.             :* *:***.