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M. thermoresistible (build 8) TH_1330 (menB)

annotation: PROBABLE NAPHTHOATE SYNTHASE MENB (DIHYDROXYNAPHTHOIC ACID SYNTHETASE) (DHNA SYNTHETASE)
coordinates: 2527918 - 2528832
length: 305

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1330menB-100% (305)PROBABLE NAPHTHOATE SYNTHASE MENB (DIHYDROXYNAPHTHOIC ACID SYNTHETASE) (DHNA SYNTHETASE)
M. thermoresistible (build 8)TH_4071-2e-1928.27% (283) PUTATIVE Enoyl-CoA hydratase/isomerase
M. thermoresistible (build 8)TH_4102-2e-1829.62% (260) PUTATIVE short chain enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0562cmenB1e-15887.83% (304) naphthoate synthase
M. gilvum PYR-GCKMflv_0025-1e-15687.04% (301) naphthoate synthase
M. tuberculosis H37RvRv0548cmenB1e-15887.83% (304) naphthoate synthase
M. leprae Br4923MLBr_02263menB1e-15485.53% (304) naphthoate synthase
M. abscessus ATCC 19977MAB_3945-1e-14781.64% (305) naphthoate synthase MenB (dihydroxynaphthoic acid synthetase)
M. marinum MMMAR_0895menB1e-15988.49% (304) naphthoate synthase, MenB
M. avium 104MAV_4596menB1e-15188.66% (291) naphthoate synthase
M. smegmatis MC2 155MSMEG_1075menB1e-16993.40% (303) naphthoate synthase
M. ulcerans Agy99MUL_0648menB1e-16088.49% (304) naphthoate synthase
M. vanbaalenii PYR-1Mvan_0947-1e-15888.37% (301) naphthoate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0025|M.gilvum_PYR-GCK          -----------MSTPGSNPFDPSLWEPVSGFDDLTDITYHR-AVD-----
Mvan_0947|M.vanbaalenii_PYR-1       -----------MSAPGTNPFDASLWEPVAGFEDLTDITYHRHVVDGA---
TH_1330|M.thermoresistible__bu      --------------MSDNPFDPELWRVVDGFDDLTDITYHRHVVDGE---
MSMEG_1075|M.smegmatis_MC2_155      ---------MSSQAASDNPFDPAMWERVPGFDDLTDITYHRHVLDGA---
Mb0562c|M.bovis_AF2122/97           MVAPAGEQGRSSTALSDNPFDAKAWRLVDGFDDLTDITYHRHVDD-----
Rv0548c|M.tuberculosis_H37Rv        MVAPAGEQGRSSTALSDNPFDAKAWRLVDGFDDLTDITYHRHVDD-----
MLBr_02263|M.leprae_Br4923          --------------MSNNPFDAKLWRLIDGFGDLTDITYHRYVNG-----
MMAR_0895|M.marinum_M               --------------MSDNPFDAGVWRLVNGFDELTDITYHRHVQD-----
MUL_0648|M.ulcerans_Agy99           --------------MSDNPFDAGVWRLVNGFDELTDITYHRHVQD-----
MAV_4596|M.avium_104                ---------------------------MAGFDDLTDITYHRHVDD-----
MAB_3945|M.abscessus_ATCC_1997      --------MTQDDGQTANPFDPTRWQPVPGFEDLTDITYHRNVEHGSNGA
                                                               : ** :******** .       

Mflv_0025|M.gilvum_PYR-GCK          --QPTVRIAFDRPEVRNAFRPHTVDELYRVLDHARMSSNVGVVLLTGNGP
Mvan_0947|M.vanbaalenii_PYR-1       -RKPTVRIAFDRPEVRNAFRPHTVDELYRVLDHARMSSDVGVVLLTGNGP
TH_1330|M.thermoresistible__bu      -PQPTVRVAFNRPEVRNAFRPHTVDELYRALDHARMSPDVGVVLLTGNGP
MSMEG_1075|M.smegmatis_MC2_155      -RQPTVRVAFDRPEVRNAFRPHTVDELYRVLDHARMSSDVGVILLTGNGP
Mb0562c|M.bovis_AF2122/97           ---ATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGP
Rv0548c|M.tuberculosis_H37Rv        ---ATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGP
MLBr_02263|M.leprae_Br4923          ---ATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGP
MMAR_0895|M.marinum_M               ---ATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGP
MUL_0648|M.ulcerans_Agy99           ---ATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGP
MAV_4596|M.avium_104                ---ATVRVAFDRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGP
MAB_3945|M.abscessus_ATCC_1997      RQTGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMTSDVGAVLLTGNGP
                                        ***:**:******************.******:.:**.:*******

Mflv_0025|M.gilvum_PYR-GCK          SPKDGGWAFCSGGDQRIRGRSGYQYASGDTAETVDPARAGRLHILEVQRL
Mvan_0947|M.vanbaalenii_PYR-1       SAKDGGWAFCSGGDQRIRGRSGYQYASGETAETVDPARAGRLHILEVQRL
TH_1330|M.thermoresistible__bu      SPKDGGWAFCSGGDQRIRGRTGYQYASGETADTVDAARAGRLHILEVQRL
MSMEG_1075|M.smegmatis_MC2_155      SPKDGGWAFCSGGDQRIRGRTGYQYASGETAETVDPARAGRLHILEVQRL
Mb0562c|M.bovis_AF2122/97           SPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRL
Rv0548c|M.tuberculosis_H37Rv        SPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRL
MLBr_02263|M.leprae_Br4923          SPRDGVWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRL
MMAR_0895|M.marinum_M               SPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDIARAGRLHILEVQRL
MUL_0648|M.ulcerans_Agy99           SPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDIARAGRLHILEVQRL
MAV_4596|M.avium_104                SPKDGGWAFCSGGDQRIRGRSGYQYASGETADTVDPARAGRLHILEVQRL
MAB_3945|M.abscessus_ATCC_1997      SPKDGGWAFCSGGDQRIRGRTGYQYAGGETAETVDPGRAGRLHILEVQRL
                                    *.:** **************:*****.*:**:*** .*************

Mflv_0025|M.gilvum_PYR-GCK          IRFMPKPVICLVNGWAAGGGHSLHVVCDLTLASREHARFKQTDADVGSFD
Mvan_0947|M.vanbaalenii_PYR-1       IRFMPKPVICLVNGWAAGGGHSLHVVCDLTLASREHARFKQTDADVGSFD
TH_1330|M.thermoresistible__bu      IRFMPKVVICLVNGWAAGGGHSLHVTCDLTLASRQHARFKQTDADVGSFD
MSMEG_1075|M.smegmatis_MC2_155      IRFMPKVVICLVNGWAAGGGHSLHVTCDLTLASREHARFKQTDADVGSFD
Mb0562c|M.bovis_AF2122/97           IRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFD
Rv0548c|M.tuberculosis_H37Rv        IRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFD
MLBr_02263|M.leprae_Br4923          IRFMPKVVICLVNGWAAGGGHSLHVICDLTLASREHARFKQTDADVGSFD
MMAR_0895|M.marinum_M               IRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASRQHARFKQTDADVGSFD
MUL_0648|M.ulcerans_Agy99           IRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASRQHARFKQTDADVGSFD
MAV_4596|M.avium_104                IRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREHARFKQTDADVGSFD
MAB_3945|M.abscessus_ATCC_1997      IRFMPKVVIALVNGWAAGGGHSLHVVCDLTLASREHARFKQTDADVGSFD
                                    ****** **.*************** ********::**************

Mflv_0025|M.gilvum_PYR-GCK          GGYGSAYLARQAGQKFAREIFFLGRPYTAEQMHAMGAVNEVVDHAELENV
Mvan_0947|M.vanbaalenii_PYR-1       GGYGSAYLASQVGQKFAREIFFLGRAYTAEQMHAMGAVNEVVDHADLENV
TH_1330|M.thermoresistible__bu      GGFGSAYLARQTGQKFAREIFFLGRAYDAETMHQMGAVNEVVDHADLERA
MSMEG_1075|M.smegmatis_MC2_155      GGFGSAYLARQTGQKFAREIFFLGRAYDAQTMHQMGAVNEVVDHADLEKA
Mb0562c|M.bovis_AF2122/97           GGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETV
Rv0548c|M.tuberculosis_H37Rv        GGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETV
MLBr_02263|M.leprae_Br4923          GGYGSAYLARQIGQKFAREIFLLGRAYTAEQMHHMGAVNAVAEHANLETM
MMAR_0895|M.marinum_M               GGYGSAYLARQVGQKFAREIFFLGRPYTAEQMHHMGAVNEVVDHAELERV
MUL_0648|M.ulcerans_Agy99           GGYGSAYLARQVGQKFAREIFFLGRPYTAEQMHHMGAVNEVVDHAELERV
MAV_4596|M.avium_104                GGYGSAYLARQVGQKFAREIFFLGREYTAEQMHRMGAVNAVVEHAELERA
MAB_3945|M.abscessus_ATCC_1997      GGYGSAYLAKMVGQKFAREIFFLGRPYTAEQMHHMGAVNEVVDHAELENV
                                    **:******   *********:*** * *: ** ***** *.:**:**  

Mflv_0025|M.gilvum_PYR-GCK          ALQWASEINGKSPQAVRMLKYAFNLLDDGLVGQQLFAGEATRLAYMTDEA
Mvan_0947|M.vanbaalenii_PYR-1       ALQWASEINGKSPQAIRMLKYAFNLPDDGLVGQQLFAGEATRLAYMTDEA
TH_1330|M.thermoresistible__bu      GLQWAAEINGKSPTAIRMLKFAFNLIDDGLVGQQVFAGEATRLAYMTDEA
MSMEG_1075|M.smegmatis_MC2_155      GLQYAAEINGKSPQAIRMLKFAFNLIDDGLVGQQVFAGEATRLAYMTDEA
Mb0562c|M.bovis_AF2122/97           GLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEA
Rv0548c|M.tuberculosis_H37Rv        GLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEA
MLBr_02263|M.leprae_Br4923          GLEWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEA
MMAR_0895|M.marinum_M               GLQWAADINAKSPQAQRMLKYAFNLLDDGLVGQQLFAGEATRLAYMTDEA
MUL_0648|M.ulcerans_Agy99           GLQWAADINAKSPQAQRMLKYAFNLLDDGLVGQQLFAGEATRLAYMTDEA
MAV_4596|M.avium_104                GIEWAREINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEA
MAB_3945|M.abscessus_ATCC_1997      ALEWAAAINGKSPQAQRMLKYAFNLTDDGLVGQQLFAGEATRLAYMTDEA
                                    .:::*  **.*** * ****:**** ********:***************

Mflv_0025|M.gilvum_PYR-GCK          VEGRDAFLEKRDPDWSPFPRYF
Mvan_0947|M.vanbaalenii_PYR-1       VEGRDAFLEKRDPDWSPFPRYF
TH_1330|M.thermoresistible__bu      VEGRDAFLEKRDPDWSAFPRYF
MSMEG_1075|M.smegmatis_MC2_155      VEGRDAFLEKRDPDWSRFPRYF
Mb0562c|M.bovis_AF2122/97           VEGRDAFLQKRPPDWSPFPRYF
Rv0548c|M.tuberculosis_H37Rv        VEGRDAFLQKRPPDWSPFPRYF
MLBr_02263|M.leprae_Br4923          VEGRDAFLQKRAPDWSSFPRYF
MMAR_0895|M.marinum_M               VEGRDAFLEKRAPDWSGFPRYF
MUL_0648|M.ulcerans_Agy99           VEGRDAFLEKRAPDWSGFPRYF
MAV_4596|M.avium_104                VEGRDAFLEKRPPDYSRFPRYF
MAB_3945|M.abscessus_ATCC_1997      VEGRDSFLQKREPDWSPYPWHY
                                    *****:**:** **:* :* ::