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M. thermoresistible (build 8) TH_1315 ()

annotation: PROBABLE CONSERVED MEMBRANE PROTEIN
coordinates: 2499012 - 2500166
length: 385

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1315-100% (385)PROBABLE CONSERVED MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0232c-1e-15171.05% (380) hypothetical protein Mb0232c
M. gilvum PYR-GCKMflv_0421-1e-17878.81% (387) hypothetical protein Mflv_0421
M. tuberculosis H37RvRv0227c-1e-15271.32% (380) hypothetical protein Rv0227c
M. leprae Br4923MLBr_02581-1e-14565.52% (377) putative integral membrane protein
M. abscessus ATCC 19977MAB_4474-1e-14969.41% (376) hypothetical protein MAB_4474
M. marinum MMMAR_0476-1e-14969.09% (385) hypothetical protein MMAR_0476
M. avium 104MAV_4942-1e-14967.95% (390) hypothetical protein MAV_4942
M. smegmatis MC2 155MSMEG_0317-1e-17878.65% (384) hypothetical protein MSMEG_0317
M. ulcerans Agy99MUL_1126-1e-14768.31% (385) hypothetical protein MUL_1126
M. vanbaalenii PYR-1Mvan_0250-1e-17878.29% (387) hypothetical protein Mvan_0250

CLUSTAL 2.0.9 multiple sequence alignment


TH_1315|M.thermoresistible__bu      --------------MGLGAALLIAALLLSTYTKSKIAKIPLDLDTTLVSD
MSMEG_0317|M.smegmatis_MC2_155      MNRAVALRIAACGLLGLGAALLIAALLLTTYTKGKIAKIPLDIDTSLVSD
Mflv_0421|M.gilvum_PYR-GCK          MNRAVALRIAACGIMGLGAALLIAALLLSTYTQGKIAKIPLTVDSTLVSD
Mvan_0250|M.vanbaalenii_PYR-1       MNRAVALRIAACGIMGLGAALLIAALLLSTYTQGKIAKIPLDIDATLISD
MLBr_02581|M.leprae_Br4923          MNRAVILRFTACGIIGLGAAFLIAALLLATYTSSRITKIPLDIDATLVSE
MAV_4942|M.avium_104                MNRAVMLRFAACGIIGLGAALLIAALLLTTYTTSRITKVPLDVDATLISD
Mb0232c|M.bovis_AF2122/97           -----MLRFAACGAIGLGAALLIAALLLSTYTTRRIAEIPLDIDATLISD
Rv0227c|M.tuberculosis_H37Rv        -----MLRFAACGAIGLGAALLIAALLLSTYTTSRIAEIPLDIDATLISD
MMAR_0476|M.marinum_M               MNRAVMLRIAALGTIGLGSALLIAALLLSTYTSSKITKIPLDIDATLISE
MUL_1126|M.ulcerans_Agy99           -----MLRIAALGTIGLGSALLIAALLLSTYTSSKITKIPLDIDATLISE
MAB_4474|M.abscessus_ATCC_1997      MNRGVMMRIAACGLLGLGSALIIAALLLSTYTSNRLAKIPLDWDATLVSE
                                                  :***:*::******:***  :::::**  *::*:*:

TH_1315|M.thermoresistible__bu      GTAVAFDPESLAGERFVIDPDVPVVLQEQVSVEAPANADVVTLQVGSTLR
MSMEG_0317|M.smegmatis_MC2_155      GTATAFDPDSLVAERFKIDRDVPVALQQQMSVEAPSNADVVTFQVGTTLR
Mflv_0421|M.gilvum_PYR-GCK          GTATAFDPASLLGERFVVNEDVPVVSQQQTSVEAPANADVVTLQVGTSLR
Mvan_0250|M.vanbaalenii_PYR-1       GTGTAFDPASLLGERFVINEDVPVVMQQQMTVESPANADVVTLQVGTTLK
MLBr_02581|M.leprae_Br4923          GNGTALDSSSLSSEHIIVNQNVPLVSQQQITVESPANVDVVTFQVGVSIR
MAV_4942|M.avium_104                GTGTALDSASLSTDHVVVNQNVPLVSQQQISVESPANADVVTLQVGSSLR
Mb0232c|M.bovis_AF2122/97           GTGTALDSASLATEHIVVNQDVPLVSQQQVTVESPANADVVTLQVGSSLR
Rv0227c|M.tuberculosis_H37Rv        GTGTALDSASLATEHIVVNQDVPLVSQQQVTVESPANADVVTLQVGSSLR
MMAR_0476|M.marinum_M               GKGSALDSASLATDHIVINQNVPLVSQQQITVESPANADVVTLQVGTSVR
MUL_1126|M.ulcerans_Agy99           GKGSALDSASLATDHIVINQNVPLVSQQQITVESPANADVVTLQVGTSVR
MAB_4474|M.abscessus_ATCC_1997      GKGRALDPASLSGQKFIADPDRPLALQEQISTVSPADATKVGLQAGITLR
                                    *.. *:*. **  ::.  : : *:. *:* :. :*::.  * :*.* :::

TH_1315|M.thermoresistible__bu      RTDKQQDTGLLLAMVDTVTVNRETAEAVSRDTNPGGAVQKPRAIEATQPP
MSMEG_0317|M.smegmatis_MC2_155      RTDRQQDAGLLLALVDTVTMNRNTAEAVSSENNPGGAVQKPRAIEDEKPP
Mflv_0421|M.gilvum_PYR-GCK          RTDQQGDNGLLLAMVDTVTMNRETAEAVSSETNPGGSVQKPRAMEDENPP
Mvan_0250|M.vanbaalenii_PYR-1       RSDQQKDEGLLLAMVDTVTVNRQTAMAVSSETNPGGSVQKPRAIEDENPP
MLBr_02581|M.leprae_Br4923          RTDKQKDTGLLLAVVDTVTLNRKTAMAVSDDTHTGGSIQKPRGFTDENPP
MAV_4942|M.avium_104                RTDKQKDTGLLLAIVDTVTLNRKTATAVSDDTHTGGAVQKPRTINDENPP
Mb0232c|M.bovis_AF2122/97           RTDKQKDSGLLLAIVDTVTLNRKTAMAVSDDTHTGGAVQKPRGLNDENPP
Rv0227c|M.tuberculosis_H37Rv        RTDKQKDSGLLLAIVDTVTLNRKTAMAVSDDTHTGGAVQKPRGLNDENPP
MMAR_0476|M.marinum_M               RTDKQKDTGLLLAIVDTVTLNRHTAMAISDDTHTGGTVQKPRGFGDESPP
MUL_1126|M.ulcerans_Agy99           RTDKQKDTGLLLAIVDTVTLNRHTAMAISDDTHTGGTVQKPRGFGDESPP
MAB_4474|M.abscessus_ATCC_1997      RTDKQGDAGLVLATVDTVTVDRHSAEAISSDDNPGGSVQKPRAIEDETPP
                                    *:*:* * **:** *****::*.:* *:* : :.**::**** :    **

TH_1315|M.thermoresistible__bu      TNIALPHEGLTYRFPFDTEKKTYPVFDPIAQQAFDANYSGEEDVNGLTTY
MSMEG_0317|M.smegmatis_MC2_155      TNIALPHEGLTYRFPFDTEKKTYPFFDPIAQKAFDANYDGEEDVNGLTTY
Mflv_0421|M.gilvum_PYR-GCK          TSIALPHEGLTYRFPFDTEKKTYQVFDPIAQEPFDANYSGEEDVNGLTAL
Mvan_0250|M.vanbaalenii_PYR-1       TSIALPHEGLTYRFPFDTEKKTYQVFDPIAQKAFDANYSGEEDVNGLTAY
MLBr_02581|M.leprae_Br4923          TAIPLRHDGLSYRFPFHTEKKTYPYFDPVAQKTFDVNYQNQEDINGLTTY
MAV_4942|M.avium_104                TAIPLRHDGLSYRFPFHTEKKTYPYFDPIAQKPFDVNYDSQEDVNGLTTY
Mb0232c|M.bovis_AF2122/97           TAIPLRHDGLSYRFPFHTEKKTYPYFDPIAQKAFDANYEGEEDVNGLTTY
Rv0227c|M.tuberculosis_H37Rv        TAIPLRHDGLSYRFPFHTEKKTYPYFDPIAQKAFDANYEGEEDVNGLTTY
MMAR_0476|M.marinum_M               TAIPLRHEGLSYRFPFHTEKKSYPYFDPIAQKPFDANYDSEEDVNGLTTY
MUL_1126|M.ulcerans_Agy99           TAIPLRHEGLSYRFPFHTEKKSYPYFDPIAQKPFDANYDSEEDVNGLTTY
MAB_4474|M.abscessus_ATCC_1997      TTIALKHEGLSYRFPFDTEKKTYQYFDVVAQRAFDANYTGEEDVNGLTAY
                                    * *.* *:**:*****.****:*  ** :**..**.** .:**:****: 

TH_1315|M.thermoresistible__bu      RFTQNVGFDAEGELVDPVRYSSLYDNDE-DAQVTARAAQWGVEG-ESDEP
MSMEG_0317|M.smegmatis_MC2_155      RFVQNVGYDADGKLADPIKYSSLYEDDA-DASVTARAEVWGVPG-EPDES
Mflv_0421|M.gilvum_PYR-GCK          KFTQNVGFDADGKLVEPVRFASLYDDDA-DAQVTARASLWGLEG-DPEEP
Mvan_0250|M.vanbaalenii_PYR-1       KFTQNIGFDADGKLVEPVKFASLYDDDA-DSQATATAKLWGLEG-DPEES
MLBr_02581|M.leprae_Br4923          RFTQNVGYDADGKLVAPITYPSLYASDE-DGKITTTAAIWGLSG-DPSEQ
MAV_4942|M.avium_104                KFTQNVGYNADGKLVAPVAYPSLYADQATDSKFTAPASMWGIQGGDPNEQ
Mb0232c|M.bovis_AF2122/97           RFTQNVGYTPEGKLVAPLKYPSLYAGDE-DGKVTTSAAMWGLPG-DPNEQ
Rv0227c|M.tuberculosis_H37Rv        RFTQNVGYTPEGKLVAPLKYPSLYAGDE-DGKVTTSAAMWGLPG-DPNEQ
MMAR_0476|M.marinum_M               RFTQNIGYNSEGKLVAPVKYPSLYAGDE-DGKVTTTAAMWGVPG-EPDEE
MUL_1126|M.ulcerans_Agy99           RFTQNIGYNSEGKLVAPVKYPSLYAGDE-DGKVTTTAAMWGVPG-EPDEE
MAB_4474|M.abscessus_ATCC_1997      HFTQNVGYDANGKLVEPVAYPSLYDKDE-DSKVTARAQQWGVEAEHEDDE
                                    :*.**:*: .:*:*. *: :.***  :  *.. *: *  **: . . .: 

TH_1315|M.thermoresistible__bu      ITMTRYYAAQRTFWVDPVTGTIVKSEERAHHYYARDALEPEVTFVDYTVT
MSMEG_0317|M.smegmatis_MC2_155      ITMDRFYAASRTFWVDPVSGTIVKSEEHGYQYYAREALKPEVTYVDFKVT
Mflv_0421|M.gilvum_PYR-GCK          ITMTRYYAAQRTFWVDPVSGTIVKQTDRGYHYYAREALKPEMTYVDYTVT
Mvan_0250|M.vanbaalenii_PYR-1       ITMTRYYAAQRTFWVDPVSGTIVKKTDRGYQYYAREALKPEVTFVDYTVT
MLBr_02581|M.leprae_Br4923          ITMTRYYAAQRTFWVDPVSGTIVKETEHVNHYFARDTLKPEVTLADYKVT
MAV_4942|M.avium_104                ITMTRFYAAQRTFWVDPVSGTIVKQTEHAHHYFARDPLKPELTLADYKVT
Mb0232c|M.bovis_AF2122/97           ITMTRYYAAQRTFWVDPVSGTIVKETERANHYFARDPLKPEVTFADYQVT
Rv0227c|M.tuberculosis_H37Rv        ITMTRYYAAQRTFWVDPVSGTIVKETERANHYFARDPLKPEVTFADYQVT
MMAR_0476|M.marinum_M               ITMTRYYAAQRTFWVDPVTGTIVKQTVHANHYFAREAMKPEVTLADYKVT
MUL_1126|M.ulcerans_Agy99           IAMTRYYAAQRTFWVDPVTGTIVKQTVHANHYFAREAMKPEVTLANYKVT
MAB_4474|M.abscessus_ATCC_1997      ITMTRYYAAQREFWVDPVSGIIVKSKEHALHYYSRDALKPEVPMVDYTVQ
                                    *:* *:***.* ******:* ***.  :  :*::*:.::**:. .:: * 

TH_1315|M.thermoresistible__bu      STEETVEEQVAAARDERDRLGLWGRVLPITFTALGLVSLVGGALLGSFSL
MSMEG_0317|M.smegmatis_MC2_155      TNEESVESQVAAASDERDRIALWTRILPITFTALGLVSLVGGAVLGSFAL
Mflv_0421|M.gilvum_PYR-GCK          TDEESVESQVASAQDERDRISLWGRILPITFTALGLVALVGGAVLGTFSL
Mvan_0250|M.vanbaalenii_PYR-1       SNEETVEAQVAAAQDERDRVSLWGRILPITFTALGLVALVGGALLGTFSL
MLBr_02581|M.leprae_Br4923          STEETIESQVNSARDERDRLALWSRVLPITFTAVGLITLLSGGFLASFSL
MAV_4942|M.avium_104                SNEDTVESQVNAARDERDRLALWSRVLPITFTAVGLIALVGGGLLASFSL
Mb0232c|M.bovis_AF2122/97           STEETVESQVNAARDERDRLALWSRVLPITFTAAGLVALVGGGLFASFSL
Rv0227c|M.tuberculosis_H37Rv        STEETVESQVNAARDERDRLALWSRVLPITFTAAGLVALVGGGLFASFSL
MMAR_0476|M.marinum_M               SNEDTVETQVNTARDERDRLALWSRVLPITFTAIGLVALVGGGLLTSFSL
MUL_1126|M.ulcerans_Agy99           SNEDTVETQVNTARDERDRLALWSRVLPITFTAIGWVALVGGGLLTSFSL
MAB_4474|M.abscessus_ATCC_1997      SNDETVEKQVKAARDTRDSLAIWSNILPITFAALGVVALVGGGLLGSFSL
                                    : ::::* ** :* * ** :.:* .:*****:* * ::*:.*..: :*:*

TH_1315|M.thermoresistible__bu      RAESALIDPGLDDAEHGFFGP---EGRPVPGAEAQTEKLPAQRP------
MSMEG_0317|M.smegmatis_MC2_155      RTESTLIDPGLDTADHGFFDT---QGIQVPGAEAKTEKLPAQRP------
Mflv_0421|M.gilvum_PYR-GCK          RAESMLIDPGLDGAGDRFYGKRDEEGEPVPGAEAMTEKLPAQRP------
Mvan_0250|M.vanbaalenii_PYR-1       RAESLLIDPGLDDTGGRFFGRRGDEGEPVPGAEAMTEKLPAQRP------
MLBr_02581|M.leprae_Br4923          RTESALTESGLDRANRDAFGHCR-TEEPVPGAEAETEKLPTQRPELRDSS
MAV_4942|M.avium_104                RSESALTDPGLDRGDQDFFGRSG-LEEPVSGAEAETEKLPTQRPDLRSE-
Mb0232c|M.bovis_AF2122/97           RTEGALMAASGDRDDHDYR-RGG-FEEPVPGAEAETEKLPTQRPDFPREP
Rv0227c|M.tuberculosis_H37Rv        RTEGALMAASGDRDDHDYR-RGG-FEEPVPGAEAETEKLPTQRPDFPREP
MMAR_0476|M.marinum_M               RTESILMDPSLDRDDTDFLRRVG-LEQPVPGAEAETEKLPAQRPDSSDD-
MUL_1126|M.ulcerans_Agy99           RTESILMDPSLDRDDTDFLRRVG-LEQPVPGAEAETEKLPAQRPDSSDD-
MAB_4474|M.abscessus_ATCC_1997      RAESALIDPGLDTVDHGFFGRRG--PEKPPASEADTDKFPSPRNHL----
                                    *:*. *  .. *                 ..:** *:*:*: *       

TH_1315|M.thermoresistible__bu      ------------SDLPPDRPI----------
MSMEG_0317|M.smegmatis_MC2_155      ------------TDLPPDRPI----------
Mflv_0421|M.gilvum_PYR-GCK          ------------SDLPPDRPV----------
Mvan_0250|M.vanbaalenii_PYR-1       ------------SDLPPDKPV----------
MLBr_02581|M.leprae_Br4923          ILSVSAHRRRSSESSPPNSGPADPGHPERG-
MAV_4942|M.avium_104                ----------SGPDEPTEAGPTEAKPPDRE-
Mb0232c|M.bovis_AF2122/97           NGSDPPRLGSAQPPPPPDAGHPDPGPPERR-
Rv0227c|M.tuberculosis_H37Rv        SGSDPPRLGSAQPPPPPDAGHPDPGPPERR-
MMAR_0476|M.marinum_M               -GPDSDKTPPDSAESSSESGSAEPSGPEERT
MUL_1126|M.ulcerans_Agy99           -GPDSDKTPPDSAESSSESGSAEPSGPEERT
MAB_4474|M.abscessus_ATCC_1997      -------------------------------