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NRAVALRIAACGIMGLGAALLIAALLLSTYTQGKIAKIPLDIDATLISDGTGTAFDPASLLGERFVINED VPVVMQQQMTVESPANADVVTLQVGTTLKRSDQQKDEGLLLAMVDTVTVNRQTAMAVSSETNPGGSVQKP RAIEDENPPTSIALPHEGLTYRFPFDTEKKTYQVFDPIAQKAFDANYSGEEDVNGLTAYKFTQNIGFDAD GKLVEPVKFASLYDDDADSQATATAKLWGLEGDPEESITMTRYYAAQRTFWVDPVSGTIVKKTDRGYQYY AREALKPEVTFVDYTVTSNEETVEAQVAAAQDERDRVSLWGRILPITFTALGLVALVGGALLGTFSLRAE SLLIDPGLDDTGGRFFGRRGDEGEPVPGAEAMTEKLPAQRPSDLPPDKPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0250 | - | - | 100% (401) | hypothetical protein Mvan_0250 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0232c | - | 1e-157 | 70.77% (390) | hypothetical protein Mb0232c |
| M. gilvum PYR-GCK | Mflv_0421 | - | 0.0 | 87.78% (401) | hypothetical protein Mflv_0421 |
| M. tuberculosis H37Rv | Rv0227c | - | 1e-157 | 70.77% (390) | hypothetical protein Rv0227c |
| M. leprae Br4923 | MLBr_02581 | - | 1e-154 | 66.07% (392) | putative integral membrane protein |
| M. abscessus ATCC 19977 | MAB_4474 | - | 1e-149 | 66.58% (392) | hypothetical protein MAB_4474 |
| M. marinum M | MMAR_0476 | - | 1e-157 | 69.50% (400) | hypothetical protein MMAR_0476 |
| M. avium 104 | MAV_4942 | - | 1e-159 | 69.38% (405) | hypothetical protein MAV_4942 |
| M. smegmatis MC2 155 | MSMEG_0317 | - | 1e-180 | 75.81% (401) | hypothetical protein MSMEG_0317 |
| M. thermoresistible (build 8) | TH_1315 | - | 1e-178 | 78.29% (387) | PROBABLE CONSERVED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1126 | - | 1e-153 | 68.78% (394) | hypothetical protein MUL_1126 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0250|M.vanbaalenii_PYR-1 MNRAVALRIAACGIMGLGAALLIAALLLSTYTQGKIAKIPLDIDATLISD
Mflv_0421|M.gilvum_PYR-GCK MNRAVALRIAACGIMGLGAALLIAALLLSTYTQGKIAKIPLTVDSTLVSD
MSMEG_0317|M.smegmatis_MC2_155 MNRAVALRIAACGLLGLGAALLIAALLLTTYTKGKIAKIPLDIDTSLVSD
TH_1315|M.thermoresistible__bu --------------MGLGAALLIAALLLSTYTKSKIAKIPLDLDTTLVSD
MLBr_02581|M.leprae_Br4923 MNRAVILRFTACGIIGLGAAFLIAALLLATYTSSRITKIPLDIDATLVSE
MAV_4942|M.avium_104 MNRAVMLRFAACGIIGLGAALLIAALLLTTYTTSRITKVPLDVDATLISD
Mb0232c|M.bovis_AF2122/97 -----MLRFAACGAIGLGAALLIAALLLSTYTTRRIAEIPLDIDATLISD
Rv0227c|M.tuberculosis_H37Rv -----MLRFAACGAIGLGAALLIAALLLSTYTTSRIAEIPLDIDATLISD
MMAR_0476|M.marinum_M MNRAVMLRIAALGTIGLGSALLIAALLLSTYTSSKITKIPLDIDATLISE
MUL_1126|M.ulcerans_Agy99 -----MLRIAALGTIGLGSALLIAALLLSTYTSSKITKIPLDIDATLISE
MAB_4474|M.abscessus_ATCC_1997 MNRGVMMRIAACGLLGLGSALIIAALLLSTYTSNRLAKIPLDWDATLVSE
:***:*::******:*** :::::** *::*:*:
Mvan_0250|M.vanbaalenii_PYR-1 GTGTAFDPASLLGERFVINEDVPVVMQQQMTVESPANADVVTLQVGTTLK
Mflv_0421|M.gilvum_PYR-GCK GTATAFDPASLLGERFVVNEDVPVVSQQQTSVEAPANADVVTLQVGTSLR
MSMEG_0317|M.smegmatis_MC2_155 GTATAFDPDSLVAERFKIDRDVPVALQQQMSVEAPSNADVVTFQVGTTLR
TH_1315|M.thermoresistible__bu GTAVAFDPESLAGERFVIDPDVPVVLQEQVSVEAPANADVVTLQVGSTLR
MLBr_02581|M.leprae_Br4923 GNGTALDSSSLSSEHIIVNQNVPLVSQQQITVESPANVDVVTFQVGVSIR
MAV_4942|M.avium_104 GTGTALDSASLSTDHVVVNQNVPLVSQQQISVESPANADVVTLQVGSSLR
Mb0232c|M.bovis_AF2122/97 GTGTALDSASLATEHIVVNQDVPLVSQQQVTVESPANADVVTLQVGSSLR
Rv0227c|M.tuberculosis_H37Rv GTGTALDSASLATEHIVVNQDVPLVSQQQVTVESPANADVVTLQVGSSLR
MMAR_0476|M.marinum_M GKGSALDSASLATDHIVINQNVPLVSQQQITVESPANADVVTLQVGTSVR
MUL_1126|M.ulcerans_Agy99 GKGSALDSASLATDHIVINQNVPLVSQQQITVESPANADVVTLQVGTSVR
MAB_4474|M.abscessus_ATCC_1997 GKGRALDPASLSGQKFIADPDRPLALQEQISTVSPADATKVGLQAGITLR
*.. *:*. ** ::. : : *:. *:* :. :*::. * :*.* :::
Mvan_0250|M.vanbaalenii_PYR-1 RSDQQKDEGLLLAMVDTVTVNRQTAMAVSSETNPGGSVQKPRAIEDENPP
Mflv_0421|M.gilvum_PYR-GCK RTDQQGDNGLLLAMVDTVTMNRETAEAVSSETNPGGSVQKPRAMEDENPP
MSMEG_0317|M.smegmatis_MC2_155 RTDRQQDAGLLLALVDTVTMNRNTAEAVSSENNPGGAVQKPRAIEDEKPP
TH_1315|M.thermoresistible__bu RTDKQQDTGLLLAMVDTVTVNRETAEAVSRDTNPGGAVQKPRAIEATQPP
MLBr_02581|M.leprae_Br4923 RTDKQKDTGLLLAVVDTVTLNRKTAMAVSDDTHTGGSIQKPRGFTDENPP
MAV_4942|M.avium_104 RTDKQKDTGLLLAIVDTVTLNRKTATAVSDDTHTGGAVQKPRTINDENPP
Mb0232c|M.bovis_AF2122/97 RTDKQKDSGLLLAIVDTVTLNRKTAMAVSDDTHTGGAVQKPRGLNDENPP
Rv0227c|M.tuberculosis_H37Rv RTDKQKDSGLLLAIVDTVTLNRKTAMAVSDDTHTGGAVQKPRGLNDENPP
MMAR_0476|M.marinum_M RTDKQKDTGLLLAIVDTVTLNRHTAMAISDDTHTGGTVQKPRGFGDESPP
MUL_1126|M.ulcerans_Agy99 RTDKQKDTGLLLAIVDTVTLNRHTAMAISDDTHTGGTVQKPRGFGDESPP
MAB_4474|M.abscessus_ATCC_1997 RTDKQGDAGLVLATVDTVTVDRHSAEAISSDDNPGGSVQKPRAIEDETPP
*:*:* * **:** *****::*.:* *:* : :.**::**** : **
Mvan_0250|M.vanbaalenii_PYR-1 TSIALPHEGLTYRFPFDTEKKTYQVFDPIAQKAFDANYSGEEDVNGLTAY
Mflv_0421|M.gilvum_PYR-GCK TSIALPHEGLTYRFPFDTEKKTYQVFDPIAQEPFDANYSGEEDVNGLTAL
MSMEG_0317|M.smegmatis_MC2_155 TNIALPHEGLTYRFPFDTEKKTYPFFDPIAQKAFDANYDGEEDVNGLTTY
TH_1315|M.thermoresistible__bu TNIALPHEGLTYRFPFDTEKKTYPVFDPIAQQAFDANYSGEEDVNGLTTY
MLBr_02581|M.leprae_Br4923 TAIPLRHDGLSYRFPFHTEKKTYPYFDPVAQKTFDVNYQNQEDINGLTTY
MAV_4942|M.avium_104 TAIPLRHDGLSYRFPFHTEKKTYPYFDPIAQKPFDVNYDSQEDVNGLTTY
Mb0232c|M.bovis_AF2122/97 TAIPLRHDGLSYRFPFHTEKKTYPYFDPIAQKAFDANYEGEEDVNGLTTY
Rv0227c|M.tuberculosis_H37Rv TAIPLRHDGLSYRFPFHTEKKTYPYFDPIAQKAFDANYEGEEDVNGLTTY
MMAR_0476|M.marinum_M TAIPLRHEGLSYRFPFHTEKKSYPYFDPIAQKPFDANYDSEEDVNGLTTY
MUL_1126|M.ulcerans_Agy99 TAIPLRHEGLSYRFPFHTEKKSYPYFDPIAQKPFDANYDSEEDVNGLTTY
MAB_4474|M.abscessus_ATCC_1997 TTIALKHEGLSYRFPFDTEKKTYQYFDVVAQRAFDANYTGEEDVNGLTAY
* *.* *:**:*****.****:* ** :**..**.** .:**:****:
Mvan_0250|M.vanbaalenii_PYR-1 KFTQNIGFDADGKLVEPVKFASLYDDDA-DSQATATAKLWGLEG-DPEES
Mflv_0421|M.gilvum_PYR-GCK KFTQNVGFDADGKLVEPVRFASLYDDDA-DAQVTARASLWGLEG-DPEEP
MSMEG_0317|M.smegmatis_MC2_155 RFVQNVGYDADGKLADPIKYSSLYEDDA-DASVTARAEVWGVPG-EPDES
TH_1315|M.thermoresistible__bu RFTQNVGFDAEGELVDPVRYSSLYDNDE-DAQVTARAAQWGVEG-ESDEP
MLBr_02581|M.leprae_Br4923 RFTQNVGYDADGKLVAPITYPSLYASDE-DGKITTTAAIWGLSG-DPSEQ
MAV_4942|M.avium_104 KFTQNVGYNADGKLVAPVAYPSLYADQATDSKFTAPASMWGIQGGDPNEQ
Mb0232c|M.bovis_AF2122/97 RFTQNVGYTPEGKLVAPLKYPSLYAGDE-DGKVTTSAAMWGLPG-DPNEQ
Rv0227c|M.tuberculosis_H37Rv RFTQNVGYTPEGKLVAPLKYPSLYAGDE-DGKVTTSAAMWGLPG-DPNEQ
MMAR_0476|M.marinum_M RFTQNIGYNSEGKLVAPVKYPSLYAGDE-DGKVTTTAAMWGVPG-EPDEE
MUL_1126|M.ulcerans_Agy99 RFTQNIGYNSEGKLVAPVKYPSLYAGDE-DGKVTTTAAMWGVPG-EPDEE
MAB_4474|M.abscessus_ATCC_1997 HFTQNVGYDANGKLVEPVAYPSLYDKDE-DSKVTARAQQWGVEAEHEDDE
:*.**:*: .:*:*. *: :.*** : *.. *: * **: . . .:
Mvan_0250|M.vanbaalenii_PYR-1 ITMTRYYAAQRTFWVDPVSGTIVKKTDRGYQYYAREALKPEVTFVDYTVT
Mflv_0421|M.gilvum_PYR-GCK ITMTRYYAAQRTFWVDPVSGTIVKQTDRGYHYYAREALKPEMTYVDYTVT
MSMEG_0317|M.smegmatis_MC2_155 ITMDRFYAASRTFWVDPVSGTIVKSEEHGYQYYAREALKPEVTYVDFKVT
TH_1315|M.thermoresistible__bu ITMTRYYAAQRTFWVDPVTGTIVKSEERAHHYYARDALEPEVTFVDYTVT
MLBr_02581|M.leprae_Br4923 ITMTRYYAAQRTFWVDPVSGTIVKETEHVNHYFARDTLKPEVTLADYKVT
MAV_4942|M.avium_104 ITMTRFYAAQRTFWVDPVSGTIVKQTEHAHHYFARDPLKPELTLADYKVT
Mb0232c|M.bovis_AF2122/97 ITMTRYYAAQRTFWVDPVSGTIVKETERANHYFARDPLKPEVTFADYQVT
Rv0227c|M.tuberculosis_H37Rv ITMTRYYAAQRTFWVDPVSGTIVKETERANHYFARDPLKPEVTFADYQVT
MMAR_0476|M.marinum_M ITMTRYYAAQRTFWVDPVTGTIVKQTVHANHYFAREAMKPEVTLADYKVT
MUL_1126|M.ulcerans_Agy99 IAMTRYYAAQRTFWVDPVTGTIVKQTVHANHYFAREAMKPEVTLANYKVT
MAB_4474|M.abscessus_ATCC_1997 ITMTRYYAAQREFWVDPVSGIIVKSKEHALHYYSRDALKPEVPMVDYTVQ
*:* *:***.* ******:* ***. : :*::*:.::**:. .:: *
Mvan_0250|M.vanbaalenii_PYR-1 SNEETVEAQVAAAQDERDRVSLWGRILPITFTALGLVALVGGALLGTFSL
Mflv_0421|M.gilvum_PYR-GCK TDEESVESQVASAQDERDRISLWGRILPITFTALGLVALVGGAVLGTFSL
MSMEG_0317|M.smegmatis_MC2_155 TNEESVESQVAAASDERDRIALWTRILPITFTALGLVSLVGGAVLGSFAL
TH_1315|M.thermoresistible__bu STEETVEEQVAAARDERDRLGLWGRVLPITFTALGLVSLVGGALLGSFSL
MLBr_02581|M.leprae_Br4923 STEETIESQVNSARDERDRLALWSRVLPITFTAVGLITLLSGGFLASFSL
MAV_4942|M.avium_104 SNEDTVESQVNAARDERDRLALWSRVLPITFTAVGLIALVGGGLLASFSL
Mb0232c|M.bovis_AF2122/97 STEETVESQVNAARDERDRLALWSRVLPITFTAAGLVALVGGGLFASFSL
Rv0227c|M.tuberculosis_H37Rv STEETVESQVNAARDERDRLALWSRVLPITFTAAGLVALVGGGLFASFSL
MMAR_0476|M.marinum_M SNEDTVETQVNTARDERDRLALWSRVLPITFTAIGLVALVGGGLLTSFSL
MUL_1126|M.ulcerans_Agy99 SNEDTVETQVNTARDERDRLALWSRVLPITFTAIGWVALVGGGLLTSFSL
MAB_4474|M.abscessus_ATCC_1997 SNDETVEKQVKAARDTRDSLAIWSNILPITFAALGVVALVGGGLLGSFSL
: ::::* ** :* * ** :.:* .:*****:* * ::*:.*..: :*:*
Mvan_0250|M.vanbaalenii_PYR-1 RAESLLIDPGLDDTGGRFFGRRGDEGEPVPGAEAMTEKLPAQRP------
Mflv_0421|M.gilvum_PYR-GCK RAESMLIDPGLDGAGDRFYGKRDEEGEPVPGAEAMTEKLPAQRP------
MSMEG_0317|M.smegmatis_MC2_155 RTESTLIDPGLDTADHGFFDT---QGIQVPGAEAKTEKLPAQRP------
TH_1315|M.thermoresistible__bu RAESALIDPGLDDAEHGFFGP---EGRPVPGAEAQTEKLPAQRP------
MLBr_02581|M.leprae_Br4923 RTESALTESGLDRANRDAFGHCR-TEEPVPGAEAETEKLPTQRPELRDSS
MAV_4942|M.avium_104 RSESALTDPGLDRGDQDFFGRSG-LEEPVSGAEAETEKLPTQRPDLRSE-
Mb0232c|M.bovis_AF2122/97 RTEGALMAASGDRDDHDYR-RGG-FEEPVPGAEAETEKLPTQRPDFPREP
Rv0227c|M.tuberculosis_H37Rv RTEGALMAASGDRDDHDYR-RGG-FEEPVPGAEAETEKLPTQRPDFPREP
MMAR_0476|M.marinum_M RTESILMDPSLDRDDTDFLRRVG-LEQPVPGAEAETEKLPAQRPDSSDD-
MUL_1126|M.ulcerans_Agy99 RTESILMDPSLDRDDTDFLRRVG-LEQPVPGAEAETEKLPAQRPDSSDD-
MAB_4474|M.abscessus_ATCC_1997 RAESALIDPGLDTVDHGFFGRRG--PEKPPASEADTDKFPSPRNHL----
*:*. * .. * ..:** *:*:*: *
Mvan_0250|M.vanbaalenii_PYR-1 ------------SDLPPDKPV----------
Mflv_0421|M.gilvum_PYR-GCK ------------SDLPPDRPV----------
MSMEG_0317|M.smegmatis_MC2_155 ------------TDLPPDRPI----------
TH_1315|M.thermoresistible__bu ------------SDLPPDRPI----------
MLBr_02581|M.leprae_Br4923 ILSVSAHRRRSSESSPPNSGPADPGHPERG-
MAV_4942|M.avium_104 ----------SGPDEPTEAGPTEAKPPDRE-
Mb0232c|M.bovis_AF2122/97 NGSDPPRLGSAQPPPPPDAGHPDPGPPERR-
Rv0227c|M.tuberculosis_H37Rv SGSDPPRLGSAQPPPPPDAGHPDPGPPERR-
MMAR_0476|M.marinum_M -GPDSDKTPPDSAESSSESGSAEPSGPEERT
MUL_1126|M.ulcerans_Agy99 -GPDSDKTPPDSAESSSESGSAEPSGPEERT
MAB_4474|M.abscessus_ATCC_1997 -------------------------------