For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1300 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 2469342 - 2470625
length: 428

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1300-100% (428)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3749c-0.075.94% (424) hypothetical protein Mb3749c
M. gilvum PYR-GCKMflv_1280-0.077.75% (427) GntR family transcriptional regulator
M. tuberculosis H37RvRv3722c-0.075.94% (424) hypothetical protein Rv3722c
M. leprae Br4923MLBr_02336-0.075.29% (425) hypothetical protein MLBr_02336
M. abscessus ATCC 19977MAB_0305-0.074.94% (423) putative aminotransferase
M. marinum MMMAR_5241-0.075.47% (424) transcriptional regulator
M. avium 104MAV_0381-0.077.75% (427) aspartate transaminase
M. smegmatis MC2 155MSMEG_6286-0.078.87% (426) aspartate transaminase
M. ulcerans Agy99MUL_4316-0.075.47% (424) transcriptional regulator
M. vanbaalenii PYR-1Mvan_5535-0.079.63% (427) GntR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_1300|M.thermoresistible__bu      -------------------------------------VSFHSLGRDELTA
MSMEG_6286|M.smegmatis_MC2_155      -------------------------------------MSFQSLGRDDLLA
Mflv_1280|M.gilvum_PYR-GCK          -------------------------------------MSFHSLGRDELRA
Mvan_5535|M.vanbaalenii_PYR-1       -------------------------------------MSFHSLGRDELRA
MAB_0305|M.abscessus_ATCC_1997      -------------------------------------MSFLSLGSDELAA
Mb3749c|M.bovis_AF2122/97           -------------------------------------MSFDSLSPQELAA
Rv3722c|M.tuberculosis_H37Rv        -------------------------------------MSFDSLSPQELAA
MMAR_5241|M.marinum_M               ------------------------------------MVSFDSLSPEELAA
MUL_4316|M.ulcerans_Agy99           ------------------------------------MVSFDSLSPEELAA
MLBr_02336|M.leprae_Br4923          MRGVPYLGGAVTSAYGSGSAHDLRMSHSVRWRKGVPLVSFDSLSPDELAA
MAV_0381|M.avium_104                ------------------------------------MVSLESLTPAELAE
                                                                         :*: **   :*  

TH_1300|M.thermoresistible__bu      QYELQRRSYAELQAKNLQLDLTRGKPSPAQLDLSNRLLSLPGD--DDYRD
MSMEG_6286|M.smegmatis_MC2_155      QHELQQRNYAELQAKQLKLDLTRGKPSPEQLDLSNGLLSLPGDGADAYRD
Mflv_1280|M.gilvum_PYR-GCK          QHELQQRNYADLKAKSLRLDLTRGKPCSEQLDLSNGLLALPGTGAGAYLD
Mvan_5535|M.vanbaalenii_PYR-1       QHDEQQRNYAELQAKNLRLDLTRGKPSPDQLDLSNGLLELP--GADAFRD
MAB_0305|M.abscessus_ATCC_1997      QHRLQQENYSQLKAKGLSLDLTRGKPAPEQLDLSNGLLALPGE--GDYLD
Mb3749c|M.bovis_AF2122/97           LHARHQQDYAALQGMKLALDLTRGKPSAEQLDLSNQLLSLPG---DDYRD
Rv3722c|M.tuberculosis_H37Rv        LHARHQQDYAALQGMKLALDLTRGKPSAEQLDLSNQLLSLPG---DDYRD
MMAR_5241|M.marinum_M               LHVRHEQDYANLRGKGLSLDLTRGKPSSEQLDLSNQLLSLPGG--QDYRD
MUL_4316|M.ulcerans_Agy99           LHVRHEQDYANLRGKGLSLDLTRGKPSSEQLDLSNQLLSLPGG--QDYRD
MLBr_02336|M.leprae_Br4923          VHARHQQDYAELQGRKLALDLTRGKPSPEQLNLSNQLLYLPG---DDYRD
MAV_0381|M.avium_104                VHARHQQGYADLQAKKLSLDLTRGKPAPAQLDLSNALLSLPG---DDYRD
                                     :  :...*: *:.  * ********.. **:*** ** **      : *

TH_1300|M.thermoresistible__bu      ADGTDVRNYGGLHGLPELRAIFGELLGIPVPNLIAANNASLELMHDILTF
MSMEG_6286|M.smegmatis_MC2_155      GHGTDTRNYGGVQGLPELRAIFAELLGLPVENLIAGNNASLEMMHDSVVF
Mflv_1280|M.gilvum_PYR-GCK          RDGTDTRNYGGLHGLPELRAIFGEVLGIPVPNLIAGNNASLEFMHDAIVY
Mvan_5535|M.vanbaalenii_PYR-1       AEGTDTRNYGGLHGLPELRTIFSELLGIPVPNLIAGNNASLEFMHDVVVY
MAB_0305|M.abscessus_ATCC_1997      GNGTDTRNYGGGNGLPELRAIFGELLGIPAPNLIAANNASLSLMHDVIVY
Mb3749c|M.bovis_AF2122/97           PEGTDTRNYGGQHGLPGLRAIFAELLGIAVPNLIAGNNSSLELMHDIVAF
Rv3722c|M.tuberculosis_H37Rv        PEGTDTRNYGGQHGLPGLRAIFAELLGIAVPNLIAGNNSSLELMHDIVAF
MMAR_5241|M.marinum_M               PEGLDTRNYGGLHGLPALRAIFGELLGIPVQNLIAGNNSSLELMHDVTAF
MUL_4316|M.ulcerans_Agy99           PEGLDTRNYGGLHGLPALRAIFGELLGIPVQSLIAGNNSSLELMHDVTAF
MLBr_02336|M.leprae_Br4923          SEGVDTRNYGGLHGLPGLRAIFAELLGIPVPNLIAGINSSLELMHDLVVF
MAV_0381|M.avium_104                SEGTDTRNYGGLHGLPELRAIFGELLGIPVQNLIAGNNSSLELMHDLVAF
                                     .* *.***** :*** **:**.*:**:.. .***. *:**.:***  .:

TH_1300|M.thermoresistible__bu      AMLHGAPDSTRPWLKEP----VVKFLCPVPGYDRHFAITENLDVEMIPVP
MSMEG_6286|M.smegmatis_MC2_155      SLLHGGLDSPRPWSAEP----TVKFLCPAPGYDRHFAITESFGIENVPVP
Mflv_1280|M.gilvum_PYR-GCK          SLLHGGVDSPRPWSQEP----VVKFLCPSPGYDRHFAITESLGIEMITVP
Mvan_5535|M.vanbaalenii_PYR-1       SLLHGGVDSPRPWIDDLRNGAGVKFLCPAPGYDRHFAITESLGIEMVPVP
MAB_0305|M.abscessus_ATCC_1997      SLLHGNVDSPRPWRQES----TLKFLCPAPGYDRHFAITESFGIEMIPIP
Mb3749c|M.bovis_AF2122/97           SMLYGGVDSPRPWIQEQDG---IKFLCPVPGYDRHFAITETMGIEMIPIP
Rv3722c|M.tuberculosis_H37Rv        SMLYGGVDSPRPWIQEQDG---IKFLCPVPGYDRHFAITETMGIEMIPIP
MMAR_5241|M.marinum_M               SMLYGGVDSPRPWVQEPDG---IKFLCPVPGYDRHFAITETMGVEMIPVP
MUL_4316|M.ulcerans_Agy99           SMLYGGVDSPRPWVKEPDG---IKFLCPVPGYDRHFAITETMGVEMIPVP
MLBr_02336|M.leprae_Br4923          LVLYGGLDSSRPWKDEAS----VKFLCPVPGYDRHFAITETMGIEMIPIP
MAV_0381|M.avium_104                SMLYGGVDSQRPWKDEPS----VKFLCPVPGYDRHFAITETMGIEMIPVP
                                     :*:*  ** ***  :      :***** ***********.:.:* :.:*

TH_1300|M.thermoresistible__bu      IRDDGPDVDMIEELVAADPAIKGMWCIPVYSNPTGVTVSWENARRLMQMK
MSMEG_6286|M.smegmatis_MC2_155      IREDGPDVDVIEQLVASDPTIKGIWCVPVYSNPTGATYSTDVIRRLVQMP
Mflv_1280|M.gilvum_PYR-GCK          LREDGPDMDLIEELVATDPAIKGIWCIPVYSNPTGSTYSWETVRRLVQMQ
Mvan_5535|M.vanbaalenii_PYR-1       LREDGPDVDLIEELVAVDPAIKGMWCVPVYSNPTGTTYAWETVRRLVQME
MAB_0305|M.abscessus_ATCC_1997      LREDGPDVDLIEELVAADPAIKGMWTVPVFSNPTGTVYSWEVARRLVQMN
Mb3749c|M.bovis_AF2122/97           MLQDGPDVDLIEELVAVDPAIKGMWTVPVFGNPSGVTYSWETVRRLVQMR
Rv3722c|M.tuberculosis_H37Rv        MLQDGPDVDLIEELVAVDPAIKGMWTVPVFGNPSGVTYSWETVRRLVQMR
MMAR_5241|M.marinum_M               MLEDGPDVDLIEELVAVDPTIKGMWTVPVFGNPTGVTYSWETVRRLVQMQ
MUL_4316|M.ulcerans_Agy99           MLEDGPDVDLIEELVAVDPTIKGMWTVPVFGNPTGVTYSWETVRRLVQMQ
MLBr_02336|M.leprae_Br4923          MRHDGPDVELIEELVVVDPTIKGMWTVPVFGNPTGVTYSWETVRRLVQMR
MAV_0381|M.avium_104                MLSDGPDVGLIEELVAADPAIKGMWTVPVFGNPTGVTYSWDTVLRLVQMR
                                    :  ****: :**:**. **:***:* :**:.**:* . : :   **:** 

TH_1300|M.thermoresistible__bu      TAANDFRVFWDNAYAVHTLTHEFERQIDVLGLAAAAGNQNRPLVFASTSK
MSMEG_6286|M.smegmatis_MC2_155      TAAKDFRLMWDNAYAVHTLTDEFVEPVDVLGLAAAAGNPNRPLVFASTSK
Mflv_1280|M.gilvum_PYR-GCK          TAASDFRIMWDNAYAVHTLTRDFAQQVDILGLAAAANHANRPLVFASTSK
Mvan_5535|M.vanbaalenii_PYR-1       TAATDFRLMWDNAYAVHTLTHDFVKQVDILGLAAAANHANRPLVFASTSK
MAB_0305|M.abscessus_ATCC_1997      TAAPDFRLFWDNAYAVHTLTHDFVRNVDLLGLAETAGHPNRPLIFASTSK
Mb3749c|M.bovis_AF2122/97           TAAPDFRLFWDNAYAVHTLTLDFPRQVDVLGLAAKAGNPNRPYVFASTSK
Rv3722c|M.tuberculosis_H37Rv        TAAPDFRLFWDNAYAVHTLTLDFPRQVDVLGLAAKAGNPNRPYVFASTSK
MMAR_5241|M.marinum_M               TAAPDFRLFWDNAYMVHTLTPDFIRQVDVLGLAAKAGNPHRPYVFASTSK
MUL_4316|M.ulcerans_Agy99           TAAPDFRLFWDNAYMVHTLTPDFIRQVDVLGLAAKAGNPHRPYVFASTSK
MLBr_02336|M.leprae_Br4923          TAAPDFRLFWDNAYAVHTLTHDFIRQVDVLGLAAKAGNPHRPYVFASTSK
MAV_0381|M.avium_104                TAAPDFRLFWDNAYAVHTLTHDFIRQVDVLGLAAAAGNPNRPYVFASTSK
                                    *** ***::***** ***** :* . :*:****  *.: :** :******

TH_1300|M.thermoresistible__bu      ITFAGAGVSFFGGSLANIAWYLQHASKKTIGPDKVNQLRHLRFFGDADGV
MSMEG_6286|M.smegmatis_MC2_155      ITFAGAGVSFLGASADNIAWYLKHAGKKSIGPDKVNQLRHLRFFGDADGV
Mflv_1280|M.gilvum_PYR-GCK          ITFAGSGVSFLGGSLGNIAWYLQHAGKRSIGPDKINQLRHARFFGDADGV
Mvan_5535|M.vanbaalenii_PYR-1       ITFAGAGVSFFGGSLGNIAWYLQHAGKKSIGPDKVNQLRHARFFGDADGV
MAB_0305|M.abscessus_ATCC_1997      ITFAGAGVSFLGGSLANIAWYLQHAGKRSIGPDKVNQLRHLRFFGDAEGV
Mb3749c|M.bovis_AF2122/97           ITFAGGGVSFFGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFFGDADGV
Rv3722c|M.tuberculosis_H37Rv        ITFAGGGVSFFGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFFGDADGV
MMAR_5241|M.marinum_M               ITFAGGGVSFFGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFFGDADGV
MUL_4316|M.ulcerans_Agy99           ITFAGGGVSFFGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFFGDADGV
MLBr_02336|M.leprae_Br4923          ITFAGGGVSFLGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFFGDAEGV
MAV_0381|M.avium_104                ITFAGAGVSFFGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFFRDADGV
                                    *****.****:*.*  ******::*.*::*****:***** *** **:**

TH_1300|M.thermoresistible__bu      RLHMHRHRELLAPKFALVAEILENRLGESKIASWTEPKGGYFVNLDVLPG
MSMEG_6286|M.smegmatis_MC2_155      RRQMQRHRELIAPKFALVAEILEDRLGESKIASWTDPKGGYFVSLDVWPG
Mflv_1280|M.gilvum_PYR-GCK          RLHMQRHQEILAPKFALALEILDERLGGSKIASWTEPKGGYFISLDVLPG
Mvan_5535|M.vanbaalenii_PYR-1       RLHMQRHQQLLAPKFALALEILEDRLGDSKIASWTEPKGGYFISLDVLPG
MAB_0305|M.abscessus_ATCC_1997      KLHMQKHQQILAPKFQLALEILDDRLSESKIASWSEPKGGYFISLDVLDG
Mb3749c|M.bovis_AF2122/97           RLHMLRHQQILAPKFALVAEVLDQRLSESKIASWTEPKGGYFISLDVLPG
Rv3722c|M.tuberculosis_H37Rv        RLHMLRHQQILAPKFALVAEVLDQRLSESKIASWTEPKGGYFISLDVLPG
MMAR_5241|M.marinum_M               RLHMRRHQQILAPKFAVALEILDQRLSDSKIASWTEPKGGYFISLDVMPG
MUL_4316|M.ulcerans_Agy99           RLHMRRHQQILAPKFAVALEILDQRLSDSKIASWTEPKGGYFISLDVMPG
MLBr_02336|M.leprae_Br4923          RLHMLRHQQILAPKFALVEEILKQRLGDSNIASWSEPKGGYFINLDVLPG
MAV_0381|M.avium_104                RLHMLRHQQILAPKFALALEILDQRLSDSKIASWTEPKGGYFISLDVLPG
                                    : :* :*::::**** :. *:*.:**. *:****::******:.***  *

TH_1300|M.thermoresistible__bu      TAKRTVALAKAAGIAVTEAGASFPYRNDPEDKNIRIAPTFPGLDELRDAI
MSMEG_6286|M.smegmatis_MC2_155      TAKRTVALAKDAGIAVTEAGSAFPYRKDPEDKNIRIAPTFPSLPDVRDAI
Mflv_1280|M.gilvum_PYR-GCK          TAKRTVSLAKDAGIAVTEAGASFPYRKDPEDKNIRIAPTFPATSDLRAAI
Mvan_5535|M.vanbaalenii_PYR-1       TAKRTVALAKDAGIAVTEAGASFPYRKDPEDKNIRIAPTFPALSDLREAI
MAB_0305|M.abscessus_ATCC_1997      TAKRTVALAKEAGIALTEAGATFPYRNDPDDKNIRLAPTFPPLETVGAAV
Mb3749c|M.bovis_AF2122/97           TARRTVALAKDVGIAVTEAGASFPYRKDPDDKNIRIAPSFPSVPDLRNAV
Rv3722c|M.tuberculosis_H37Rv        TARRTVALAKDVGIAVTEAGASFPYRKDPDDKNIRIAPSFPSVPDLRNAV
MMAR_5241|M.marinum_M               TARRTVALAKDAGIAVTEAGASFPYRKDPEDKNIRIAPSFPSLPDLSDAV
MUL_4316|M.ulcerans_Agy99           TARRTVALAKDAGIAVTEAGASFPYRKDPEDKNIRIAPSFPSLPDLSDAV
MLBr_02336|M.leprae_Br4923          TARRTVALAKAAGIAVTEAGASFPYRKDPDDKNIRVAPSYPSMSELRNAV
MAV_0381|M.avium_104                TAKRTVALAKDAGIAVTEAGASFPYRKDPNDTNIRIAPTFPSLPDLRDAV
                                    **:***:*** .***:****::****:**:*.***:**::*    :  *:

TH_1300|M.thermoresistible__bu      DGLATCALLAATESLVGANR--------
MSMEG_6286|M.smegmatis_MC2_155      DGLATCALLAATEALLGDK---------
Mflv_1280|M.gilvum_PYR-GCK          DGLSTCALLAALEHLLAAE---------
Mvan_5535|M.vanbaalenii_PYR-1       DGLATCALLSATEQLLALPAEK------
MAB_0305|M.abscessus_ATCC_1997      DGLATCALLAATEKLLERGA--------
Mb3749c|M.bovis_AF2122/97           DGLATCALLAATETLLNQGLASSAPNVR
Rv3722c|M.tuberculosis_H37Rv        DGLATCALLAATETLLNQGLASSAPNVR
MMAR_5241|M.marinum_M               DGLATCALLAGTEALLAR------P---
MUL_4316|M.ulcerans_Agy99           DGLATCALLAGTEALLAR------P---
MLBr_02336|M.leprae_Br4923          DGLATCALLAASESLLNARC--------
MAV_0381|M.avium_104                DGLATCALLAASESLLARDRV-------
                                    ***:*****:. * *: