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M. thermoresistible (build 8) TH_1145 (pabB)

annotation: para-aminobenzoate synthase, component I
coordinates: 2219020 - 2220306
length: 429

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1145pabB-100% (429)para-aminobenzoate synthase, component I
M. thermoresistible (build 8)TH_2725-3e-2629.91% (321) PUTATIVE anthranilate synthase component I
M. thermoresistible (build 8)TH_0672entC3e-2032.57% (261) PROBABLE ISOCHORISMATE SYNTHASE ENTC (ISOCHORISMATE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1032cpabB1e-16668.79% (423) aminodeoxychorismate synthase component I
M. gilvum PYR-GCKMflv_1926-1e-16772.13% (409) para-aminobenzoate synthase component I
M. tuberculosis H37RvRv1005cpabB1e-16668.79% (423) aminodeoxychorismate synthase component I
M. leprae Br4923MLBr_00236pabB1e-15567.96% (412) aminodeoxychorismate synthase component I
M. abscessus ATCC 19977MAB_1124c-1e-14763.83% (412) aminodeoxychorismate synthase component I
M. marinum MMMAR_4488pabD1e-15466.83% (419) para-aminobenzoate synthase component, PabD
M. avium 104MAV_1127pabB1e-16068.52% (413) para-aminobenzoate synthase component I
M. smegmatis MC2 155MSMEG_5446pabB1e-16973.87% (398) para-aminobenzoate synthase component I
M. ulcerans Agy99MUL_4660pabD1e-15265.63% (419) aminodeoxychorismate synthase component I
M. vanbaalenii PYR-1Mvan_4807-1e-16169.51% (410) para-aminobenzoate synthase component I

CLUSTAL 2.0.9 multiple sequence alignment


TH_1145|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5446|M.smegmatis_MC2_155      --------------------------------------------------
Mb1032c|M.bovis_AF2122/97           MALAARTATPPGTETGAGHGSNLAWELSTRTKSPRSHLRCENPQFCQART
Rv1005c|M.tuberculosis_H37Rv        --------------------MNLAWELSTRTKSPRSHLRCENPQFCQART
MMAR_4488|M.marinum_M               -------------------------------------MACENPSFCQAKA
MUL_4660|M.ulcerans_Agy99           -------------------------------------MACENPSFCQAKA
MLBr_00236|M.leprae_Br4923          --------------------------------------------------
MAV_1127|M.avium_104                --------------------------------------------------
Mflv_1926|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4807|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1124c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_1145|M.thermoresistible__bu      VRIEALGELG---PATAVLRTLEAATAARGLPPPAALIGDWFGARAVIAP
MSMEG_5446|M.smegmatis_MC2_155      MRIERFCTPDGQADAPSVLRSVAAAASAAGLAPPAALIGDWFGSRAVIAP
Mb1032c|M.bovis_AF2122/97           VRIDRLGDLG---GAPAVLRAVGRATSRLDLPPPAALTGEWFGALAVIAP
Rv1005c|M.tuberculosis_H37Rv        VRIDRLGDLG---GAPAVLRAVGRATSRLDLPPPAALTGEWFGALAVIAP
MMAR_4488|M.marinum_M               VLIDRLGDLG---SAPQVLRAVGHATRQLDLPPPAALTGEWFGALAVIAP
MUL_4660|M.ulcerans_Agy99           VLIDRLGDLG---SAPQVLRAVGHATRQLDLPPPAALTGEWFGALAVIAP
MLBr_00236|M.leprae_Br4923          MRIERLGNLG---DAPRVLRSLGDATTGLDLPPPAALTGEWFDALAIIAP
MAV_1127|M.avium_104                MRIDRLGDLG---PAPQVLRAVGDVTRRLGLPPPAALTGDWFDALAVIAP
Mflv_1926|M.gilvum_PYR-GCK          MRIERLGDLG---DAPSVLRALGVATAHLGLAPPAALIGDWFGSRAVIAP
Mvan_4807|M.vanbaalenii_PYR-1       MRIERLGDLG---SAPTVLRTLAAAASASGIAPPAALLGDWFSSRAVIAP
MAB_1124c|M.abscessus_ATCC_199      MHVQQLGDLG---DPPAVLRSLAAAARDTQRPAPAALIGSWYGSRAIIAP
                                    : :: :   .    .. ***::  .:     ..**** *.*:.: *:***

TH_1145|M.thermoresistible__bu      SVAVEPVAPDAVFAGPTG-VGGTA-----VGGGWFGYLSXPDSPDAGDRS
MSMEG_5446|M.smegmatis_MC2_155      TVTALPAEPDAVFDVPQGSAEGAA-----VGGGWFGYLSYPD-PGACESA
Mb1032c|M.bovis_AF2122/97           SVSIQPVSGDDVFSGPPGTGGPDATG--AVGGGWVGYLSYPD-AGADGRP
Rv1005c|M.tuberculosis_H37Rv        SVSIQPVSGDDVFSGPPGTGGPDATG--AVGGGWVGYLSYPD-AGADGRP
MMAR_4488|M.marinum_M               SVSVRPVTSTDTFPIRSGADTAAASVPGAVGGGWVGYLSYPD-PGADGHG
MUL_4660|M.ulcerans_Agy99           SVSVRPVTSTDTFPIRRGADTAAASVPGAVGGGWVGYLSYPD-PGADGHG
MLBr_00236|M.leprae_Br4923          SLSVQPVDVNDAFAVQLDARTPDSAV--AVGGGWVGYLSYPD-PAADKQP
MAV_1127|M.avium_104                SLPVRPVPPGDVFAVG-TARTPQPPH---VGGGWIGYLSYPD-GGADAKP
Mflv_1926|M.gilvum_PYR-GCK          SVSVSAVAPPTVFDVTPGYRCDG-----AVGGGWFGYLSYPD-AGADGVG
Mvan_4807|M.vanbaalenii_PYR-1       SLIAGEVAPRDAFAVTPGSRCDG-----PVGGGWFGYLSYPD-GGADGLG
MAB_1124c|M.abscessus_ATCC_199      SLATRPVLPRQAFGGKASHVGTVAPG--AVGGGWIGYLGYPD-RAATGRA
                                    ::    .    .*                *****.***. **   *    

TH_1145|M.thermoresistible__bu      PESRAARLPEAAGGWSDCVLRQDRDGRWWYESLTGTTVPDWVVAALRTPQ
MSMEG_5446|M.smegmatis_MC2_155      P-----RIPVAAGGWSDCVLRQDTEGQWWYESLAGAPLPAWLRDLAPTP-
Mb1032c|M.bovis_AF2122/97           H-----RIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADWLASALATTR
Rv1005c|M.tuberculosis_H37Rv        H-----RIPEAAGGWTDCVLRRDRDGQWWYESLSGAPIADWLASALATTR
MMAR_4488|M.marinum_M               G-----RIPEAAGGWTDSVLRRDRDGQWWYESLSGAPMPDWLRNALSATP
MUL_4660|M.ulcerans_Agy99           G-----RIPEAAGGWTDSVLRRERDGQWWYENLSGAPMPDWLGNALSATP
MLBr_00236|M.leprae_Br4923          N-----RIPEAAGGWTDCVLRRDRGAQWWYESLSGAPMPGWLAAALATTP
MAV_1127|M.avium_104                N-----RIPEAAGGWTDCVLRRDRDGQWWYESLTGAPMPRWLAGALAAPA
Mflv_1926|M.gilvum_PYR-GCK          P-----RIPEAAGGWSDSVLRCDRDGAWWHESLSGATMSGWIEQALRSPA
Mvan_4807|M.vanbaalenii_PYR-1       P-----RIPQAAGGWADTVLRCDRDGVWWHESLSGAALPGWVTEAVQSVP
MAB_1124c|M.abscessus_ATCC_199      Q-----RLPAAAGGWTNAVLRLDEDECWWYESLLDQECPEWILHALTHPC
                                          *:* *****:: *** :    **:*.* .   . *:        

TH_1145|M.thermoresistible__bu      P-----SRPHIVRWTPPDRXAHRFGVTACLDAIGAGEIYQACVCTQFVGR
MSMEG_5446|M.smegmatis_MC2_155      ------SRPHTVDWVPPDRGAHRRGVLACLEAIAAGEVYQACVCTRFTGR
Mb1032c|M.bovis_AF2122/97           ASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGT
Rv1005c|M.tuberculosis_H37Rv        ASVARPAPACRIDWEPADRAAHRDGVLACLEAIGAGEVYQACVCTQFAGT
MMAR_4488|M.marinum_M               GLSTRPAATCLIDWGTADRHAHREGVLACLDAIAAGEVYQACVCTQFTGT
MUL_4660|M.ulcerans_Agy99           GLSARPAATCLIDWGTADRHAHREGVLACLDAIAAGEVYQACVCTQFTGT
MLBr_00236|M.leprae_Br4923          ----APARNCQVDWERTDWGAHRDGVLACLEAIRAGEIYQACVCTQFTGT
MAV_1127|M.avium_104                G----PPRPCRIDWDVADRAAHRDGVLACLEAIRAGEVYQACVCTQFRGT
Mflv_1926|M.gilvum_PYR-GCK          E-----PGRATVTWEPADRDAHRLGVLACLDAIAAGEVYQACVCTQFTGV
Mvan_4807|M.vanbaalenii_PYR-1       D-----PRDAVVTWGEPDRHAHRRGVLACLEAIAAGEVYQACVCTQFAGV
MAB_1124c|M.abscessus_ATCC_199      E-----PAPWSIDWTAPDREHHRGAVGRCLEAIAAGEVYQACVCTQFRGS
                                          .    : *  .*   ** .*  **:** ***:*******:* * 

TH_1145|M.thermoresistible__bu      IDGAPIDFFADTVARTGPARAAYLAGRWGAVASLSPELFLRRTGEHIASS
MSMEG_5446|M.smegmatis_MC2_155      LDGSPSDFFADAVARTAPARAAYVAGDWGAVASLSPELFLSRRGSSVSSS
Mb1032c|M.bovis_AF2122/97           VTGSPLDFFIDGFGRTAPSRSAFVAGPWGAVASLSPELFLRRRGSVVTSS
Rv1005c|M.tuberculosis_H37Rv        VTGSPLDFFIDGFGRTAPSRSAFVAGPWGAVASLSPELFLRRRGSVVTSS
MMAR_4488|M.marinum_M               VAGDPLDFFIDGVARTSPARAAYVAGDWGAIASLSPELFLQRRGDTVASS
MUL_4660|M.ulcerans_Agy99           VAGDPLDFFIDGVARTSPARAAYVAGDWGAIASLSPELFLQRRGDTVTSS
MLBr_00236|M.leprae_Br4923          VTGAPLDFFIAVVARTAPARAAYIAGPWGAVASLSPELFLRRRGAGVTSS
MAV_1127|M.avium_104                VGGAPLDFFVDGVARTDPARAAYVEGEWGAVASLSPELFLRRRGTVVTSS
Mflv_1926|M.gilvum_PYR-GCK          LDGDPLEFFTDAVTRTAPARAAYVAGDWGAVASLSPELFLRRCGDAVASS
Mvan_4807|M.vanbaalenii_PYR-1       LAGAPVDFFAEAAARTVPARAAFVAGDWGAVASLSPELFLRRCGEAVTSS
MAB_1124c|M.abscessus_ATCC_199      LTGKALDFFADAVTRTAPARAAYLAGIWGAVASLSPELFLRRNGTDVCSS
                                    : * . :**     ** *:*:*:: * ***:********* * *  : **

TH_1145|M.thermoresistible__bu      PIKGTLPRDADPAALRASVKDVAENIMIVDLVRNDLGRIARTGSVTVPEL
MSMEG_5446|M.smegmatis_MC2_155      PIKGTLPRHADPAGLRASVKDVAENVMIVDLVRNDLGRVARTGSVTVPEL
Mb1032c|M.bovis_AF2122/97           PIKGTLPLDAPPSALRASAKEVAENIMIVDLVRNDLGRVAVTGTVTVPEL
Rv1005c|M.tuberculosis_H37Rv        PIKGTLPLDAPPSALRASAKEVAENIMIVDLVRNDLGRVAVTGTVTVPEL
MMAR_4488|M.marinum_M               PIKGTLPLDAWPSALRASPKEVAENIMIVDLVRNDLGRVAITGTVTVPEL
MUL_4660|M.ulcerans_Agy99           PIKGTLPLDAWPSALRASPKEVAENIMIVDLVRNDLGRVAITGTVTVPEL
MLBr_00236|M.leprae_Br4923          PIKGTLPLAAWPSALQASAKEVAENIMIVDLVRNDLGRVAITGTVTVPEL
MAV_1127|M.avium_104                PIKGTLPLDAWPSALRASAKEVAENIMIVDLVRNDLGRVATVGTVSVPEL
Mflv_1926|M.gilvum_PYR-GCK          PIKGTLPRSADPAALRASVKDVAENIMIVDLVRNDLGRVARTGSVAVPEL
Mvan_4807|M.vanbaalenii_PYR-1       PIKGTLPDFADPATLRASVKDVAENIMIVDLVRNDLGRVARTGSVSVPEL
MAB_1124c|M.abscessus_ATCC_199      PIKGTLAATEDPAALLTSIKDVAENVMITDLVRNDLGRIADTGTVTVPEL
                                    ******.    *: * :* *:****:**.*********:* .*:*:****

TH_1145|M.thermoresistible__bu      LAVRPAPGVWHLVSTVAARVDPAVPMAAVLAAAFPPASVTGTPKLRARQL
MSMEG_5446|M.smegmatis_MC2_155      LAVKPAPGVWHLVSTVAAEVEQCVPMGALLDAAFPPASVTGTPKGRAREL
Mb1032c|M.bovis_AF2122/97           LVVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTGTPKLRARQL
Rv1005c|M.tuberculosis_H37Rv        LVVRPAPGVWHLVSTVSARVPLEEPMSALLDAAFPPASVTGTPKLRARQL
MMAR_4488|M.marinum_M               LVVRRAPGVWHLVSTVSAQVPVELPTSALLDATFPPASVTGTPKLRARQL
MUL_4660|M.ulcerans_Agy99           LVVRRAPGVWHLVSTVSAQVPVELPTSALLDATFPPASVTGTPKLRARQL
MLBr_00236|M.leprae_Br4923          LVVRHAPGVWHLVSTVTAQVPVELPMAALLDATFPPASITGTPKLRARKL
MAV_1127|M.avium_104                LVVRRAPGVWHLVSTVSAQVPTELPTSALLDAAFPPASVTGTPKHRARQL
Mflv_1926|M.gilvum_PYR-GCK          LAVRPAPGVWHLVSTVTAQVPSELPTSALLDATFPPASVTGTPKLRAREL
Mvan_4807|M.vanbaalenii_PYR-1       LAVRPAPGVWHLVSTVSARVPEDTPTAVLLDATFPPASVTGTPKSRARGL
MAB_1124c|M.abscessus_ATCC_199      LAVHPAPGVWHLVSTVAAKVPDEATAGDLLAAAFPPASVTGTPKTRARQL
                                    *.*: ***********:*.*    . . :* *:*****:***** *** *

TH_1145|M.thermoresistible__bu      LSRWEPFRRGVYCGTVGLASPVAGCELNVAIRTVEFDPHGAAVLGVGGGI
MSMEG_5446|M.smegmatis_MC2_155      LRAWEPGLRGIYCGTVGLASPVAGCELNVAIRTVEFGADGSAVLGVGGGI
Mb1032c|M.bovis_AF2122/97           ISQWERYRRGIYCGTVGLASPVAGCELNVAIRTVEFDTAGNAVLGVGGGI
Rv1005c|M.tuberculosis_H37Rv        ISQWERYRRGIYCGTVGLASPVAGCELNVAIRTVEFDTAGNAVLGVGGGI
MMAR_4488|M.marinum_M               ISQWEQRRRGIYCGTVGLASPIAGCELNVAIRTVEFDTVGNAVLGVGGGI
MUL_4660|M.ulcerans_Agy99           ISQWEQRRRGIYCGTVGLVSPIAGCELNVAIRTVEFDTIGNAVLGVGGGI
MLBr_00236|M.leprae_Br4923          ISQWEHRRRGIYCGTVGLASPIAGCELNVAIRTVEFDTAGNAVLGVGGGI
MAV_1127|M.avium_104                LSKWEPATRGIYCGTIGLASPVAGCELNVAIRTVEFDAAGGAVLGVGGGI
Mflv_1926|M.gilvum_PYR-GCK          LTGWERNRRGIYCGTVGLASPSAGCELNVAIRTVEFAAERTAVLGVGGGI
Mvan_4807|M.vanbaalenii_PYR-1       LTGWEPHRRGIYCGTVGLASPVAGCELNVAIRTVEFGADGSAVLGVGGGI
MAB_1124c|M.abscessus_ATCC_199      LRQWEAEHRGVYCGTIGMLSPAAGLELNVAIRTVEIAPDGSAVLGVGGGI
                                    :  **   **:****:*: ** ** **********: .   *********

TH_1145|M.thermoresistible__bu      TADSDPDREWQECLDKAAPFVGADRGPRLGSRPQDGVVQLTT
MSMEG_5446|M.smegmatis_MC2_155      TADSDPDREWEECLHKAASIVGPVTDQSLERSTAS-------
Mb1032c|M.bovis_AF2122/97           TADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR---
Rv1005c|M.tuberculosis_H37Rv        TADSDPDAEWAECLHKAAPIVGLPAATRTTPARLASKVR---
MMAR_4488|M.marinum_M               TADSDPGAEWEECLHKAAPVVGLPAPTTATRVG---------
MUL_4660|M.ulcerans_Agy99           TADSDPGAEWEECQHKAAPVVGLPAPTTATRVG---------
MLBr_00236|M.leprae_Br4923          TADSDPDAELQECLHKAAPILRLASVATVASVG---------
MAV_1127|M.avium_104                TADSDPDAEWAECLHKASPIVGLPSIAAASSAG---------
Mflv_1926|M.gilvum_PYR-GCK          TADSDPDREWQECLDKAAPIIG---RAVGSLSRA--------
Mvan_4807|M.vanbaalenii_PYR-1       TADSDPDLEWEECLHKAAPIVNAVPVAVPVQPRARSTAS---
MAB_1124c|M.abscessus_ATCC_199      TADSDADAEWQECLHKAAATIGLTAIAELNPAL---------
                                    *****.. *  ** .**:. :