For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1040 (trpD)

annotation: Probable anthranilate phosphoribosyltransferase TrpD
coordinates: 2052685 - 2053743
length: 353

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1040trpD-100% (353)Probable anthranilate phosphoribosyltransferase TrpD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2215ctrpD1e-15679.08% (349) anthranilate phosphoribosyltransferase
M. gilvum PYR-GCKMflv_2957trpD1e-16985.63% (348) anthranilate phosphoribosyltransferase
M. tuberculosis H37RvRv2192ctrpD1e-15679.08% (349) anthranilate phosphoribosyltransferase
M. leprae Br4923MLBr_00883trpD1e-15177.30% (348) anthranilate phosphoribosyltransferase
M. abscessus ATCC 19977MAB_1970trpD1e-14977.08% (349) anthranilate phosphoribosyltransferase
M. marinum MMMAR_3236trpD1e-15578.39% (347) anthranilate phosphoribosyltransferase TrpD
M. avium 104MAV_2301trpD1e-15881.74% (345) anthranilate phosphoribosyltransferase
M. smegmatis MC2 155MSMEG_4258trpD1e-17787.07% (348) anthranilate phosphoribosyltransferase
M. ulcerans Agy99MUL_3549trpD1e-15478.10% (347) anthranilate phosphoribosyltransferase
M. vanbaalenii PYR-1Mvan_3556trpD1e-17286.78% (348) anthranilate phosphoribosyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1040|M.thermoresistible__bu      ------------------------------------------MT------
MSMEG_4258|M.smegmatis_MC2_155      ------------------------------------------MTSGPSQP
Mflv_2957|M.gilvum_PYR-GCK          ------------------------------------------MTTPPPRP
Mvan_3556|M.vanbaalenii_PYR-1       ------------------------------------------MTTPPPQL
MMAR_3236|M.marinum_M               ----------------------------------------MVLSSEASSA
MUL_3549|M.ulcerans_Agy99           ----------------------------------------MVLSSEASSA
Mb2215c|M.bovis_AF2122/97           ----------------------------------------MALSAEGSSG
Rv2192c|M.tuberculosis_H37Rv        ----------------------------------------MALSAEGSSG
MLBr_00883|M.leprae_Br4923          ----------------------------------------MVLSSQPPSS
MAV_2301|M.avium_104                MNSTRVWNFAICGGARRAPAPTGPFAARLGPLCPAWDHRRVALSSESSAA
MAB_1970|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_1040|M.thermoresistible__bu      ----------LADTPAWASVLARLTTNESLPVGHAAWAMDQIMTGAATPA
MSMEG_4258|M.smegmatis_MC2_155      FPSA----SGPDDGPSWPRILGRLTTGQNLPNGHAAWAMDQIMTGAATPA
Mflv_2957|M.gilvum_PYR-GCK          AAPT----TDPGDTPTWAMILGRLTTGQSLLPGQTAWAMDQIMTGVATPA
Mvan_3556|M.vanbaalenii_PYR-1       ASAQ----NPSGDTPTWAMILGRLTTGQGLAPGQTAWAMDQIMTGTATPA
MMAR_3236|M.marinum_M               ADHS---AAAPIPTSSWPQLLGRLTEGKHLEPGQAGWAMEQIMSGNARPA
MUL_3549|M.ulcerans_Agy99           ADHS---AAAPIPTSSWPQLLGRLTEGKHLEPGQAGWAMEQIMSGNARPA
Mb2215c|M.bovis_AF2122/97           GSRGGSPKAEAASVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPA
Rv2192c|M.tuberculosis_H37Rv        GSRGGSPKAEAASVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPA
MLBr_00883|M.leprae_Br4923          -------RSATGSVLSWPQVLGRLTAGQDLTRGQAAWAMGQVMTGNARPA
MAV_2301|M.avium_104                SAAR---RPSGGPATSWRQVLARLTGGDDLARGQAAWAMDQIMTGEASPA
MAB_1970|M.abscessus_ATCC_1997      -----------MLEHSWPRVLGELTNRRDLTAGQAAWAMDQIMTGTATPA
                                                   :*  :*..**    *  *::.*** *:*:* * **

TH_1040|M.thermoresistible__bu      QIAAFAVALRMKRPTPAEVHELAEIMLSHARRVPTDEIGTDT----VDIV
MSMEG_4258|M.smegmatis_MC2_155      QISGFAVSMKMKRPTASEVRELADIMLTHARRVPTDEIGTDT----VDIV
Mflv_2957|M.gilvum_PYR-GCK          QIAAFAVSMKMKRPTSAEVTELAEIMLKHALPVPTDTIGTHT----VDIV
Mvan_3556|M.vanbaalenii_PYR-1       QIAAFAVSMKMKRPTSAEVTELADIMLKHARRVPTDVIGTAT----VDIV
MMAR_3236|M.marinum_M               QVAAFAVAMKMKVPTAGEVGELADVMLAYARPMPADLIRDDT----VDIV
MUL_3549|M.ulcerans_Agy99           QVAAFAVAMKMKVPTAGEVGELADVMLAYARPMPADLIRDDT----VDIV
Mb2215c|M.bovis_AF2122/97           QIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDA----VDVV
Rv2192c|M.tuberculosis_H37Rv        QIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDA----VDVV
MLBr_00883|M.leprae_Br4923          QIAAFAVAMKMKVPTAAEVSELADVMLSHARKLPTEAICQDIGE-TVDIA
MAV_2301|M.avium_104                QIAAFAVAMQVKVPTSAEVIELAEVMLNHALPFPAGAIRDDT----VDIV
MAB_1970|M.abscessus_ATCC_1997      QIAAFGVSMRMKRPTSDEVGELADTMLSHAITFPGDPQGAQIGANAVDIV
                                    *::.*.*:: :* **. ** ***  ** :*  .*            **:.

TH_1040|M.thermoresistible__bu      GTGGDGHNTVNLSTMAAIVVAACGVPVVKHGNRAASSLSGGADTLEALGV
MSMEG_4258|M.smegmatis_MC2_155      GTGGDGANTVNLSTMASIVVAACGVPVVKHGNRAASSLSGGADTLEALGV
Mflv_2957|M.gilvum_PYR-GCK          GTGGDGANTVNLSTMASIVVAAAGVPVVKHGNRAASSLSGGADTLEALGL
Mvan_3556|M.vanbaalenii_PYR-1       GTGGDGANTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGL
MMAR_3236|M.marinum_M               GTGGDGVNTVNLSTMASIVVAAAGVPVVKHGNRAASSLAGGADTLEALGV
MUL_3549|M.ulcerans_Agy99           GTGGDGVNTVNLSTMASIVVAAAGVPVVKHGNRAASSLAGGADTLESLGV
Mb2215c|M.bovis_AF2122/97           GTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGV
Rv2192c|M.tuberculosis_H37Rv        GTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGV
MLBr_00883|M.leprae_Br4923          GTGGDGANTVNLSTMAAIVVAAAGVPVVKHGNRASSSLSGGADTLEALGV
MAV_2301|M.avium_104                GTGGDGVNTVNLSTMAAIVAAAAGVPVVKHGNRAASSLSGGADTLEELGV
MAB_1970|M.abscessus_ATCC_1997      GTGGDGANTVNLSTMASIVVAACGVPVVKHGNRAASSLAGGADTLEKLGV
                                    ****** *********:**.**.***********:***:******* **:

TH_1040|M.thermoresistible__bu      RIDLSPEEVQRSVREVGIGFAFAPQFHPSYRHASVVRREIGVPTVFNLLG
MSMEG_4258|M.smegmatis_MC2_155      RIDLGPDDVARSVREVGIGFAFAPQFHPSYKHASIVRREIGVPTVFNLLG
Mflv_2957|M.gilvum_PYR-GCK          RIDLGPDDVARCVAEVGIGFAFAPQFHPSYRHAGAVRREIGVPTVFNLLG
Mvan_3556|M.vanbaalenii_PYR-1       RIDLGPDEVARCVAEVGIGFAFAPQFHPSYRHAGAVRREIGVPTVFNLLG
MMAR_3236|M.marinum_M               RIDLGPDQVARSLNEIGIGFCFAPQFHPSYRQASVVRREIGVPTVFNLLG
MUL_3549|M.ulcerans_Agy99           RIDLGPDQVARSLNENGIGFCFAPQFHPSYRQASVVRREIGVPTVFNLLG
Mb2215c|M.bovis_AF2122/97           RIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLG
Rv2192c|M.tuberculosis_H37Rv        RIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVRREIGVPTVFNLLG
MLBr_00883|M.leprae_Br4923          RIDLGPEQVANSLAEIGIGFCFAPLFQPSYRYASAVRHEIGVPTVFNILG
MAV_2301|M.avium_104                RIDLGPEQVARSVAEVGIGFCFAPLFHPSYRHTSAVRREIGVPTVFNLLG
MAB_1970|M.abscessus_ATCC_1997      RIDLGPEQVVRSLAEVGIGFCFAPHFHPSYRYASAVRREIGVPTVFNLLG
                                    ****.*: * ..: * ****.*** *:***: :. **:*********:**

TH_1040|M.thermoresistible__bu      PLTNPAAPRAGLIGCAWADLAEVMAGVFATRGSSVLVVHGDDGLDELTTT
MSMEG_4258|M.smegmatis_MC2_155      PLTNPAGPRAGLIGCAWADLAEVMAGVFAARGSSVLVVHGDDGLDELTTT
Mflv_2957|M.gilvum_PYR-GCK          PLTNPAKPRAGLIGCAWGDLAEVMAGVFATRGSSALVVHGDDGLDELTTT
Mvan_3556|M.vanbaalenii_PYR-1       PLTNPASPRAGLIGCAWADLAEVMAGVFATRGSSVLVVHGDDGLDELTTT
MMAR_3236|M.marinum_M               PLTNPARPRAGLIGCAFADLAEIMAGVFATRGSSVLVVHGDDGLDELTTT
MUL_3549|M.ulcerans_Agy99           PLTNPARPRAGLIGCAFADLAEIMAGVFATRGSSVLVVHGDDGLDELTTT
Mb2215c|M.bovis_AF2122/97           PLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTT
Rv2192c|M.tuberculosis_H37Rv        PLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTT
MLBr_00883|M.leprae_Br4923          PLTNPAWPRAGLIGCAFGNLAEVMAGVFAARRSSVLVVHGDDGLDELTTT
MAV_2301|M.avium_104                PLTNPARPRAGLIGCAFAELAEVMAGVFAARRSSVLVVHGDDGLDELTTT
MAB_1970|M.abscessus_ATCC_1997      PLTNPARPRAGLIGCAFADLAEVTAGVFAGRGSSVLVVHGDDGLDELTTT
                                    ****** *********:.:***: ***** * **.***************

TH_1040|M.thermoresistible__bu      TTSTIWRVQAGTVERLTFDPAAFGFPRADLSALVGGDAQANAAEVRAVLG
MSMEG_4258|M.smegmatis_MC2_155      TTSTIWRVQGGTMERLTFDPAAFGFKRAEISELVGGDASENAAEARAVLG
Mflv_2957|M.gilvum_PYR-GCK          TTSTIWRVQAGTVERLTFDPAAFGFARAHVSELTGGDAEANAASAREVLG
Mvan_3556|M.vanbaalenii_PYR-1       TTSTIWRVQAGTVERLTFDPAAFGFARAHVSELTGGDAESNAASARAVLG
MMAR_3236|M.marinum_M               TTSTIWRVQAGTVDKLTFDPGDFGFARAELSQLLGGDPQANAAEARAVLG
MUL_3549|M.ulcerans_Agy99           TTSTIWRVQAGTVDKLTFDPGDFGFARAELSQLLGGDPQANAAEARAVLG
Mb2215c|M.bovis_AF2122/97           TTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLG
Rv2192c|M.tuberculosis_H37Rv        TTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLG
MLBr_00883|M.leprae_Br4923          TTSTIWRVQAGTVDKLTFDPVEFGFARAHLDDLLGGDAQTNAAKVRAVLA
MAV_2301|M.avium_104                TTSTIWRVQAGTVDRLTFDPAGFGFPRAELDDLLGGDAQTNAAEVRAVLA
MAB_1970|M.abscessus_ATCC_1997      TTSTIWRVQAGTVDKLRFDPAAFGFARARLEELVGGDPEFNAAEVRAVLA
                                    ******** .*::::* ***  *** ** :. * ***.. *** .* **.

TH_1040|M.thermoresistible__bu      GAKGPVRDAVILNAAGAMVAHAGLSSDAKWVPAWESGLARATEAIDSGAA
MSMEG_4258|M.smegmatis_MC2_155      GAKGPVRDAVVLNAAGAMVAHAGLASDAQWLPAWEAGLARAVEAIDSGAA
Mflv_2957|M.gilvum_PYR-GCK          GATGPVRDAVLLNAAGAMVAHAGLSSDAKWVPAWESGLARAKEAIDSGAA
Mvan_3556|M.vanbaalenii_PYR-1       GAKGPVRDAVVLNAAGALVAHAGLSSDAKWVPAWESGLARAKDAIDSGAA
MMAR_3236|M.marinum_M               GAAGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWQDGLQRAAVAIDSGAA
MUL_3549|M.ulcerans_Agy99           GAAGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWQDGLQRAAVAIDSGAA
Mb2215c|M.bovis_AF2122/97           GARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAA
Rv2192c|M.tuberculosis_H37Rv        GARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAA
MLBr_00883|M.leprae_Br4923          GAKGPVRDAVVLNAAGAIVAYAGLSSHAEWSPAWDDGLARASAAIDSGAA
MAV_2301|M.avium_104                GGQGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEDGLARASAAIDSGAA
MAB_1970|M.abscessus_ATCC_1997      GGTGAVRDAVLLNAAGAMVAHAGLASDAQWLPAWESALARVSTAIDSGAA
                                    *. *.*****:******:**:***:* *:* ***: .* *.  ***:***

TH_1040|M.thermoresistible__bu      EQLLARWVRFGQQL----
MSMEG_4258|M.smegmatis_MC2_155      EQLLARWVRFGQQL----
Mflv_2957|M.gilvum_PYR-GCK          EQLLARWVRFTQEL----
Mvan_3556|M.vanbaalenii_PYR-1       EQLLARWVRFTQQL----
MMAR_3236|M.marinum_M               EQLLARWVRFSQHV----
MUL_3549|M.ulcerans_Agy99           EQLLARWVRFSQHV----
Mb2215c|M.bovis_AF2122/97           EQLLARWVRFGRQI----
Rv2192c|M.tuberculosis_H37Rv        EQLLARWVRFGRQI----
MLBr_00883|M.leprae_Br4923          EQLLARWVRFSQQV----
MAV_2301|M.avium_104                EQLLARWVRFGQQL----
MAB_1970|M.abscessus_ATCC_1997      AALLDRWIAVSQRLGTGQ
                                      ** **: . :.: