For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1016 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 2013200 - 2013991
length: 264

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1016-100% (264)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1457-3e-1027.62% (286) CONSERVED HYPOTHETCAL PROTEIN
M. thermoresistible (build 8)TH_1057-3e-1030.29% (241) ribonuclease Z

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1374-1e-12178.57% (252) hypothetical protein Mb1374
M. gilvum PYR-GCKMflv_2357-1e-13184.98% (253) beta-lactamase-like protein
M. tuberculosis H37RvRv1339-1e-12178.57% (252) hypothetical protein Rv1339
M. leprae Br4923MLBr_01173-1e-12479.46% (258) hypothetical protein MLBr_01173
M. abscessus ATCC 19977MAB_1483-1e-11274.70% (253) hypothetical protein MAB_1483
M. marinum MMMAR_4043-1e-11977.47% (253) metal-dependent hydrolase
M. avium 104MAV_1556-1e-12180.24% (248) metal-dependent hydrolase of the beta-lactamase superfamily
M. smegmatis MC2 155MSMEG_4902-1e-12179.45% (253) metal-dependent hydrolase of the beta-lactamase superfamily
M. ulcerans Agy99MUL_3909-1e-11977.08% (253) metal-dependent hydrolase
M. vanbaalenii PYR-1Mvan_4288-1e-13084.19% (253) beta-lactamase-like protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2357|M.gilvum_PYR-GCK          ---------------MSVRITVLGCSGSVVGPDSPASGYLVTAPDTPPLV
Mvan_4288|M.vanbaalenii_PYR-1       ---------------MGVRITVLGCSGSVVGPDSPASGYLVTAPDTPPLV
MSMEG_4902|M.smegmatis_MC2_155      -----------------MRLTILGCSGSVVGPDSPASGYLVTAPDTVPMV
TH_1016|M.thermoresistible__bu      -----------------VRITVLGCSGSVVGPDSPASGYLLTAPNTPPLV
MLBr_01173|M.leprae_Br4923          ---------------MTVRITVLGCSGSVVGPDSPASGYLLRAPDTPPLV
MAV_1556|M.avium_104                ---------------------MLGCSGSVVGPDSPASGYLLRAPDTPPLV
Mb1374|M.bovis_AF2122/97            MRRCIPHRCIGHGTVVSVRITVLGCSGSVVGPDSPASGYLLRAPHTPPLV
Rv1339|M.tuberculosis_H37Rv         MRRCIPHRCIGHGTVVSVRITVLGCSGSVVGPDSPASGYLLRAPHTPPLV
MMAR_4043|M.marinum_M               -----------------MRITVLGCSGSVVGPDSAASGYLLRAPDTPPIV
MUL_3909|M.ulcerans_Agy99           ---------------MSVRITVLGCSGSVVGPDSAASGYLLRAPDTPPIV
MAB_1483|M.abscessus_ATCC_1997      -----------------MRVTVLGCSGSVTGPDSPASGYLLTAPDAPPLV
                                                         :*******.****.*****: **.: *:*

Mflv_2357|M.gilvum_PYR-GCK          LDFGGGVLGALQRHADPNSVHVLLSHLHADHCLDLPGLFVWRRYHPTPAP
Mvan_4288|M.vanbaalenii_PYR-1       LDFGGGVLGALQRHADPNSVHVLLSHLHADHCLDMPGLFVWRRYHPTPAP
MSMEG_4902|M.smegmatis_MC2_155      IDFGGGVLGALQRYADPNTVNVLLSHLHADHCLDLPGLFVWRRYHPMPAT
TH_1016|M.thermoresistible__bu      LDFGGGVLGALQRHADPSAVHVLLSHLHADHCLDLPGLFVWRRYHPVPPK
MLBr_01173|M.leprae_Br4923          LDFGGGVLGALQRHADPGSVHVLLSHLHADHCLDMPGLFVWRRYHPTRPV
MAV_1556|M.avium_104                IDFGGGVLGALQRYADPSSVHVLLSHLHADHCLDLPGLFVWRRYHPTRPL
Mb1374|M.bovis_AF2122/97            IDFGGGVLGALQRHADPASVHVLLSHLHADHCLDLPGLFVWRRYHPSRPS
Rv1339|M.tuberculosis_H37Rv         IDFGGGVLGALQRHADPASVHVLLSHLHADHCLDLPGLFVWRRYHPSRPS
MMAR_4043|M.marinum_M               IDFGGGVLGALQRHLDPASVHVLLSHLHADHCLDMPGLFVWRRYHPSRPK
MUL_3909|M.ulcerans_Agy99           IDFGGGVVGALQRHLDPASVHVLLSHLHADHCLDMPGLFVWRRYHPSRPK
MAB_1483|M.abscessus_ATCC_1997      IDFGGGVLGSLQRFADPGSVSVLLSHLHADHCLDLPGLFVWRRYHPNPPK
                                    :******:*:***. ** :* *************:***********  . 

Mflv_2357|M.gilvum_PYR-GCK          ERGVVYGPANTWARLGAASSPEGGEIDDFTDIFDIRHWVDAQPVEIGALT
Mvan_4288|M.vanbaalenii_PYR-1       ERGVVYGPANTWARLGAASSPEGGEIDDFTDIFEIRHWRDNQAVEIGSLT
MSMEG_4902|M.smegmatis_MC2_155      TRGVLYGPAQTWTRLGMASSPEGGEVDDFSDIFEVRNWVDGQSVTL---D
TH_1016|M.thermoresistible__bu      ERGLMYGPANTWARLGAASSPEGGEIDDFSDVFEVRNWVDNRPVRIGELT
MLBr_01173|M.leprae_Br4923          GKALLYGPDDTWLRLGAASSPYGGEIDDCSDIFDVRHWVDGEPVPLGALM
MAV_1556|M.avium_104                GKAMLYGPGDTWSRLGAASSPYGGEIDDCSDIFDVRHWVDGEPVTIGGLT
Mb1374|M.bovis_AF2122/97            GKALLYGPSDTWSRLGAASSPYGGEIDDCSDIFDVHHWADSEPVTLGALT
Rv1339|M.tuberculosis_H37Rv         GKALLYGPSDTWSRLGAASSPYGGEIDDCSDIFDVHHWADSEPVTLGALT
MMAR_4043|M.marinum_M               GKALLYGPSDTWSRLGAASSPFGGEIDDCSDIFDVRHWVDGEPVTLGGVT
MUL_3909|M.ulcerans_Agy99           GKALLYGPSDTWSRLGAASSPFGGEIDDCSDIFDVRHWVDGEPVTLGGVT
MAB_1483|M.abscessus_ATCC_1997      GKAIMYGPADTLVRVGAASAEIGGEVDDFTDIFDVFPWADGEPVQFGSLT
                                     :.::*** :*  *:* **:  ***:** :*:*::  * * ..* :    

Mflv_2357|M.gilvum_PYR-GCK          ILPRVVCHPTESYGMRITDPSGATLVYSGDTGYCDQLIELARDADVFLCE
Mvan_4288|M.vanbaalenii_PYR-1       VVPRLVCHPTESYGMRITDPSGATLVYSGDTGYCDQLIELARGADVFLCE
MSMEG_4902|M.smegmatis_MC2_155      VTPRLVCHPTESYGMRFTDPSGATLVYSGDTGYCDALVELARGADIFLCE
TH_1016|M.thermoresistible__bu      VTPRLVCHPIESYGMRITDPSGATLVYSGDTGACDAVVELARDADVFLCE
MLBr_01173|M.leprae_Br4923          IMPRLVAHPTESYGLRITDPSGASLVYSGDTGSCDQLVELARGADVFLCE
MAV_1556|M.avium_104                VTPRVVAHPTESYGLRVTDHTGASFVYSGDTGACDQLVELARGADVFLCE
Mb1374|M.bovis_AF2122/97            IVPRLVAHPTESFGLRITDPSGASLAYSGDTGICDQLVELARGVDVFLCE
Rv1339|M.tuberculosis_H37Rv         IVPRLVAHPTESFGLRITDPSGASLAYSGDTGICDQLVELARGVDVFLCE
MMAR_4043|M.marinum_M               VVPTVVAHPTESYGMRFTDSTGASLAYSGDTGMCDQLIELARGVDVFLCE
MUL_3909|M.ulcerans_Agy99           VVPTVVAHPTESYGMRFTDSTGASLAYSGDTGMCDQLIELARGVDVFLCE
MAB_1483|M.abscessus_ATCC_1997      VTPTRVAHPPESYGLRIEDSSGTVLAYSGDTGICDAVVDLARGADVFLCE
                                    : *  *.** **:*:*. * :*: :.****** ** :::***..*:****

Mflv_2357|M.gilvum_PYR-GCK          ASWTHSP-DRPPRLHLSGTEAGRAAANAGVGELLLTHIPPWTSREDVISE
Mvan_4288|M.vanbaalenii_PYR-1       ASWTHSP-SRPPRLHLSGTEAGRAAARAGVSELLLTHIPPWTSREDVISE
MSMEG_4902|M.smegmatis_MC2_155      ASWTHDP-SRPPRLHLSGTEAGRAAAEAGVGELLLTHIPPWTSREDVISE
TH_1016|M.thermoresistible__bu      ASWTHAP-DRPPGLHLSGTEAGQIAAKAGVKELLLTHIPPWTCREEVTSE
MLBr_01173|M.leprae_Br4923          ASWTHSP-DRPPNLHLSGTEAGRAAAQASVRELLLTHIPPWTSREDVISE
MAV_1556|M.avium_104                ASWTHSP-DRPPALHLSGTEAGRAAAQAGVHELLLTHIPPWTSREDVISE
Mb1374|M.bovis_AF2122/97            ASWTHSP-KHPPDLHLSGTEAGMVAAQAGVRELLLTHIPPWTSREDVISE
Rv1339|M.tuberculosis_H37Rv         ASWTHSP-KHPPDLHLSGTEAGMVAAQAGVRELLLTHIPPWTSREDVISE
MMAR_4043|M.marinum_M               ASWTHSP-DRPPDLHLSGTEAGRAAARAGVRELLLTHIPPWTSREDVISE
MUL_3909|M.ulcerans_Agy99           ASWTHSP-DRPPDLHLSGTEAGRAAARAGVRELLLTHIPPWTSREDVISE
MAB_1483|M.abscessus_ATCC_1997      ASWTHMPGHRPPDLHLSGTEAGQIATRAGVKELLLTHIPPWTSREDVIAE
                                    ***** *  :** *********  *:.*.* ***********.**:* :*

Mflv_2357|M.gilvum_PYR-GCK          AKAEFDGPVHAVVCNETFEVSRS--------
Mvan_4288|M.vanbaalenii_PYR-1       AKAEFDGPVHAVVCNETFEVTRS--------
MSMEG_4902|M.smegmatis_MC2_155      AKAEFDGPVHAVVCGEAFDITRG--------
TH_1016|M.thermoresistible__bu      AKAEFDGPVHAVQAGETFEVSAHPDRRRSGR
MLBr_01173|M.leprae_Br4923          AKAEFDGPVHAVVSGETFDIQAPERV-----
MAV_1556|M.avium_104                AKAEFDGPVHAVVCGETFDVRRSERV-----
Mb1374|M.bovis_AF2122/97            AKAEFDGPVHAVVCDETFEVRRAG-------
Rv1339|M.tuberculosis_H37Rv         AKAEFDGPVHAVVCDETFEVRRAG-------
MMAR_4043|M.marinum_M               AKAEFDGPVHAVVCDETFEVSLG--------
MUL_3909|M.ulcerans_Agy99           AKAEFDGPVHAVVCDETFEVSLG--------
MAB_1483|M.abscessus_ATCC_1997      AKSAFDGPVHAVVAGENIDL-----------
                                    **: ******** ..* :::