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M. thermoresistible (build 8) TH_1014 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 2011736 - 2012359
length: 208

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1014-100% (208)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1376-9e-8275.36% (207) putative deoxyribonucleotide triphosphate pyrophosphatase
M. gilvum PYR-GCKMflv_2359-5e-7977.78% (189) RdgB/HAM1 family non-canonical purine NTP pyrophosphatase
M. tuberculosis H37RvRv1341-9e-8275.36% (207) putative deoxyribonucleotide triphosphate pyrophosphatase
M. leprae Br4923MLBr_01175-7e-7470.67% (208) putative deoxyribonucleotide triphosphate pyrophosphatase
M. abscessus ATCC 19977MAB_1485-1e-7066.34% (205) HAM1 protein homolog (NTPase)
M. marinum MMMAR_4040-6e-8073.91% (207) Ham1-related NTPase
M. avium 104MAV_1558rdgB5e-7976.33% (207) putative deoxyribonucleotide triphosphate pyrophosphatase
M. smegmatis MC2 155MSMEG_4899rdgB2e-8174.63% (205) non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family
M. ulcerans Agy99MUL_3906-4e-8073.91% (207) putative deoxyribonucleotide triphosphate pyrophosphatase
M. vanbaalenii PYR-1Mvan_4286-2e-7977.01% (187) RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2359|M.gilvum_PYR-GCK          -------------------------------MRRVLDAAGVTGLTLVSLD
Mvan_4286|M.vanbaalenii_PYR-1       ----------------------------------MLDAAGVSGLTLLSLD
TH_1014|M.thermoresistible__bu      ---------------MTRLLVATRNRKKLAELHRVLDAAGLTGLSLLSLD
Mb1376|M.bovis_AF2122/97            ------------MALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLG
Rv1341|M.tuberculosis_H37Rv         ------------MALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLG
MLBr_01175|M.leprae_Br4923          MGVSPSREAARGVALVTKLLVASRNWKKLAELRRVLDNAGLSGLTLVSLN
MAV_1558|M.avium_104                ---------------MSPLLVASRNRKKLAELRRVLDAAGVTGLTLVSLD
MMAR_4040|M.marinum_M               ---------------MTKLLVASRNAKKLAELRRVLDAAGLSGVTLVSLN
MUL_3906|M.ulcerans_Agy99           --------------MVTKLLVASRNAKKLAELRRVLDAAGLSGVTLVSLN
MSMEG_4899|M.smegmatis_MC2_155      ---------------MTELLVASRNKKKLAELRRVLDAAGISGLRLLSLD
MAB_1485|M.abscessus_ATCC_1997      ----------------MKILVASRNPKKLAELSRVLESSGVSGVELVSLT
                                                                      :*: :*::*: *:** 

Mflv_2359|M.gilvum_PYR-GCK          DVPAFDEAPETGATFEENALAKARDAFAATGLPTVADDSGLEVDALNGMP
Mvan_4286|M.vanbaalenii_PYR-1       DVPPFDEAPETGATFEENAMAKARDAFAATGLPAVADDSGLEVDALNGMP
TH_1014|M.thermoresistible__bu      DVPPFEDAPETGATFEENALAKARDAFRATGLPTVADDSGLEVDALNGMP
Mb1376|M.bovis_AF2122/97            DVSPLPETPETGVTFEDNALAKARDAFSATGLASVADDSGLEVAALGGMP
Rv1341|M.tuberculosis_H37Rv         DVSPLPETPETGVTFEDNALAKARDAFSATGLASVADDSGLEVAALGGMP
MLBr_01175|M.leprae_Br4923          DVVPFDEAPEAGATFEDNALAKARDAFAATGLASVADDSGLEAAALGGMP
MAV_1558|M.avium_104                DVAPFEEAPETGAVFEENALAKARDAFDATGLASVADDSGLEVAALNGMP
MMAR_4040|M.marinum_M               DVAPFDEAPETGATFEENALIKAREAFAATGLPSVADDSGLTVAALNGMP
MUL_3906|M.ulcerans_Agy99           DVAPFDEAPETGATFEENALIKAREAFSATGLPSVADDSGLTVAALNGMP
MSMEG_4899|M.smegmatis_MC2_155      DVAPYDESPETGATFEENALAKARDGFEATGLACVADDSGITVAALNGMP
MAB_1485|M.abscessus_ATCC_1997      DVPEYEEVPETGASFEDNALIKAREGVKHTGLACVADDSGLAVDALNWMP
                                    **    : **:*. **:**: ***:..  ***. ******: . **. **

Mflv_2359|M.gilvum_PYR-GCK          GVLSARWSGRHGD----DAANTALLLGQIRDVPDARRGAAFVSACALVSG
Mvan_4286|M.vanbaalenii_PYR-1       GVLSARWAGRHGD----DAANTALLLGQLGDVPEERRGAAFVSACALVFG
TH_1014|M.thermoresistible__bu      GVLSARWSATAGDAATRDRANTDLLLAQLADVPDGRRGAAFVSACALVYG
Mb1376|M.bovis_AF2122/97            GVLSARWSGRYGD----DAANTALLLAQLCDVPDERRGAAFVSACALVSG
Rv1341|M.tuberculosis_H37Rv         GVLSARWSGRYGD----DAANTALLLAQLCDVPDERRGAAFVSACALVSG
MLBr_01175|M.leprae_Br4923          GVLSARWSGSYGD----DAGNTALLLAQLCDVPDERRSAAFVSACALVSE
MAV_1558|M.avium_104                GVLSARWSGRHGD----DAANTALLLAQLRDVPDERRAASFVSACALVSA
MMAR_4040|M.marinum_M               GVLSARWSGNHGD----DAGNTALLLAQLRDVPEQRRGAAFVSACALVSG
MUL_3906|M.ulcerans_Agy99           GVLSARWSGNHGD----DAGNTALLLAQLRDVPEQRRGAAFVSACALVSG
MSMEG_4899|M.smegmatis_MC2_155      GVLSARWSGTHGN----DAANTELLLAQLADVPDERRGAAFVSACALVSA
MAB_1485|M.abscessus_ATCC_1997      GVLSARWSGRHGD----DAANTALLLAQLSDIPDERRGAAFVSACALVTP
                                    *******:.  *:    * .** ***.*: *:*: **.*:********  

Mflv_2359|M.gilvum_PYR-GCK          PGEADCRVVRGEWRGTILREPRGDGGFGYDPVFLPAG---SERSAAELRP
Mvan_4286|M.vanbaalenii_PYR-1       PGEAERVVVRGEWRGSIVREARGDGGFGYDPVFLPTG---SARTAAELSP
TH_1014|M.thermoresistible__bu      PGDEDHVVVRGVWPGRIARQPRGDGGFGYDPVFIPAG---ETRTAAELSP
Mb1376|M.bovis_AF2122/97            SGE---VVVRGEWPGTIAREPRGDGGFGYDPVFVPYG---DDRTAAQLSP
Rv1341|M.tuberculosis_H37Rv         SGE---VVVRGEWPGTIAREPRGDGGFGYDPVFVPYG---DDRTAAQLSP
MLBr_01175|M.leprae_Br4923          SDE---VVVRGVWPGTIAREPRGYGGFGYDSIFIPDGPGLGGRTVAQLRP
MAV_1558|M.avium_104                SGE---VVVRGEWPGRIACEPRGDGGFGYDPVFVPDD--AGGRTAAQLSP
MMAR_4040|M.marinum_M               SGE---VVVRGEWPGAVAQEPRGAGGFGYDPVFIADG---ANRTAAELSP
MUL_3906|M.ulcerans_Agy99           SGE---VVVRGEWPGAVAQEPRGAGGFGYDPVFIADG---ANRTAAELSP
MSMEG_4899|M.smegmatis_MC2_155      SGS---TVVRGEWPGTVTREPRGDGGFGYDPVFLPEG---SERTAAELTP
MAB_1485|M.abscessus_ATCC_1997      EGEE--VVVEGRWKGSIARIPAGQNGFGYDPIFVPRG---GLRTAAELTP
                                     ..    **.* * * :   . * .*****.:*:. .     *:.*:* *

Mflv_2359|M.gilvum_PYR-GCK          EEKDASSHRGRALEALLPALRSLTWSGDRVQ
Mvan_4286|M.vanbaalenii_PYR-1       AEKDASSHRGRALAALLPSLRALI-------
TH_1014|M.thermoresistible__bu      AEKDAASHRGRALAQLVPALRRLVS------
Mb1376|M.bovis_AF2122/97            AEKDAVSHRGRALALLLPALRSLATG-----
Rv1341|M.tuberculosis_H37Rv         AEKDAVSHRGRALALLLPALRSLATG-----
MLBr_01175|M.leprae_Br4923          AEKDAFSHRFRALTLLMPALRVLAMRT----
MAV_1558|M.avium_104                AEKDAVSHRGRALRLLVPALETLARARG---
MMAR_4040|M.marinum_M               AEKDAVSHRGRALTLLLPALRALVTTQS---
MUL_3906|M.ulcerans_Agy99           AEKDAVSHRGRALTLLLPALRALVTTQP---
MSMEG_4899|M.smegmatis_MC2_155      AEKDASSHRGRALTLLVPALRALEG------
MAB_1485|M.abscessus_ATCC_1997      EEKDAVSHRGRALAALLPMLRNLVNLGRTAP
                                     **** *** ***  *:* *. *