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M. thermoresistible (build 8) TH_1004 (rhlE)

annotation: PROBABLE ATP-DEPENDENT RNA HELICASE RHLE
coordinates: 1999813 - 2001267
length: 485

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1004rhlE-100% (485)PROBABLE ATP-DEPENDENT RNA HELICASE RHLE
M. thermoresistible (build 8)TH_2231-1e-7842.98% (356) ATP-dependent rna helicase, dead/deah box family protein
M. thermoresistible (build 8)TH_4173-5e-5936.02% (397) PUTATIVE ATP-dependent RNA helicase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3237rhlE0.085.53% (380) ATP-dependent RNA helicase RhlE
M. gilvum PYR-GCKMflv_4676-0.086.52% (371) DEAD/DEAH box helicase domain-containing protein
M. tuberculosis H37RvRv3211rhlE0.085.53% (380) ATP-dependent RNA helicase RhlE
M. leprae Br4923MLBr_00811rhlE1e-17684.45% (373) putative ATP-dependent RNA helicase
M. abscessus ATCC 19977MAB_3531-1e-17581.77% (373) ATP-dependent DEAD-box RNA helicase
M. marinum MMMAR_1346rhlE1e-17885.37% (376) ATP-dependent RNA helicase RhlE
M. avium 104MAV_1401-2e-7843.42% (357) ATP-dependent rna helicase, dead/deah box family protein
M. smegmatis MC2 155MSMEG_1930-0.086.79% (371) DEAD/DEAH box helicase
M. ulcerans Agy99MUL_2533rhlE1e-17785.11% (376) ATP-dependent RNA helicase RhlE
M. vanbaalenii PYR-1Mvan_1791-0.087.06% (371) DEAD/DEAH box helicase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4676|M.gilvum_PYR-GCK          ----------------------MTPVTTHPNPT---FAQLGVRDEIVRAL
Mvan_1791|M.vanbaalenii_PYR-1       ----------------------MTPVTTHPSPT---FAQLGVRDEIVRAL
MSMEG_1930|M.smegmatis_MC2_155      --------------------------MTQLNHS---FAELGVRDEIVRAL
MAB_3531|M.abscessus_ATCC_1997      --------------------------MSHIEHT---FAQLGVRKEIARAL
Mb3237|M.bovis_AF2122/97            ----------------------MTAVKHTTEST---FAKLGARDEIVRAL
Rv3211|M.tuberculosis_H37Rv         ----------------------MTAVKHTTEST---FAKLGVRDEIVRAL
MMAR_1346|M.marinum_M               ----------------------MTALKSTTETTPKTFAELGVRDEIVRAL
MUL_2533|M.ulcerans_Agy99           ----------------------MTALKSTTETTPKTFAELGVRDEIVRAL
MLBr_00811|M.leprae_Br4923          MNRDSKTPTQNRFSHRKAFHPHMTAPTSTAEPA---FAKLGVRDEIVRAL
TH_1004|M.thermoresistible__bu      ----------------------------------------------VRAL
MAV_1401|M.avium_104                ----------------------MTLPDSSTEAASPTFADLQIHPSVLRAI
                                                                                   **:

Mflv_4676|M.gilvum_PYR-GCK          AENGIEHAFAIQELTLPLALAGDDLIGQARTGMGKTFAFGVPLLHRITTD
Mvan_1791|M.vanbaalenii_PYR-1       AENGIEHAFAIQELTLPLALAGDDLIGQARTGMGKTFAFGVPLLHRITTD
MSMEG_1930|M.smegmatis_MC2_155      AENGIEHPFAIQELTLPLALAGDDLIGQARTGMGKTYAFGVPLLHRVSSD
MAB_3531|M.abscessus_ATCC_1997      REAGIEHPFAIQELTLPLALAGSDLIGQARTGMGKTYAFGVPLLHRIATG
Mb3237|M.bovis_AF2122/97            GEEGIKRPFAIQELTLPLALDGEDVIGQARTGMGKTFAFGVPLLQRITSG
Rv3211|M.tuberculosis_H37Rv         GEEGIKRPFAIQELTLPLALDGEDVIGQARTGMGKTFAFGVPLLQRITSG
MMAR_1346|M.marinum_M               GERDIECPFAIQELTLPLALAGDDLIGQARTGMGKTFAFGVPLLQRVSSG
MUL_2533|M.ulcerans_Agy99           GERDIEGPFAIQELTLPLALAGDDLIGQARTGMGKTFAFGVPLLQRVSSG
MLBr_00811|M.leprae_Br4923          AERGIQQPFAIQELTLPLALAGDDVIGQARTGMGKTFAFGVPLLQRISVT
TH_1004|M.thermoresistible__bu      AEHGIEHPFAIQELTLPLALAGEDLIGQARTGMGKTFAFGVPLLQRITTD
MAV_1401|M.avium_104                ADVGYETPTGIQAATIPALMAGSDVVGLAQTGTGKTAAFAIPILSKIDVA
                                     : . : . .**  *:*  : *.*::* *:** *** **.:*:* ::   

Mflv_4676|M.gilvum_PYR-GCK          TE-RPLTGIPRALVVVPTRELCIQVYEDLVHASKYLMADDT--------R
Mvan_1791|M.vanbaalenii_PYR-1       TE-RPLTGIPRALIVVPTRELCIQVYEDLVGASKYLMADET--------R
MSMEG_1930|M.smegmatis_MC2_155      EN-RPLTGAPRALVVVPTRELCLQVYNDLAGAAKHLPTNDG--------R
MAB_3531|M.abscessus_ATCC_1997      VEDRPLNGTPRALVVVPTRELCIQVYEDLTKASKYLSAGD---------R
Mb3237|M.bovis_AF2122/97            DGTRPLTGAPRALVVVPTRELCLQVTDDLATAGKYLTAGPDTDDAAAVRR
Rv3211|M.tuberculosis_H37Rv         DGTRPLTGAPRALVVVPTRELCLQVTDDLATAGKYLTAGPDTDDAAAVRR
MMAR_1346|M.marinum_M               TGVRPLTGAPRALVVVPTRELCLQVTEDLAVAAKYLTATTETGD----QR
MUL_2533|M.ulcerans_Agy99           TGVRPLTGAPRALVVVPTRELCLQVTEDLAVAAKYLTATTETGD----QR
MLBr_00811|M.leprae_Br4923          TTARPLSGAPRGLVVVPTRELCLQVADDLATVAKYLTADDD-------NR
TH_1004|M.thermoresistible__bu      TE-RPLTGIPRALVVVPTRELCLQVHDDLATAAKYLKAGD---------R
MAV_1401|M.avium_104                ST------ATQALVLAPTRELALQVAEAFSRYGAHLPKIN----------
                                             .:.*::.*****.:** : :   . :*              

Mflv_4676|M.gilvum_PYR-GCK          KLTVTAIYGGRPYEPQIEALQKGVDVVVGTPGRLLDLAQQGHLQLGGLNV
Mvan_1791|M.vanbaalenii_PYR-1       KLTVTAIYGGRPYEPQIEALQKGVDVVVGTPGRLLDLAQQGHLQLGGLSV
MSMEG_1930|M.smegmatis_MC2_155      KFTVTSIYGGRPYEPQIEALRKGVDVVVGTPGRLLDLAQQGHLQLGGLSV
MAB_3531|M.abscessus_ATCC_1997      DFTVVSIYGGRPYEPQIEALRAGADVVVGTPGRLLDLAQQGHLQLGGLAM
Mb3237|M.bovis_AF2122/97            RLSVVSIYGGRPYEPQIEALRAGADVVVGTPGRLLDLCQQGHLQLGGLSV
Rv3211|M.tuberculosis_H37Rv         RLSVVSIYGGRPYEPQIEALRAGADVVVGTPGRLLDLCQQGHLQLGGLSV
MMAR_1346|M.marinum_M               PLSVVSIYGGRAYEPQIEALRAGADVVVGTPGRLLDLSQQGHLQLGGLSV
MUL_2533|M.ulcerans_Agy99           PLSVVSIYGGRAYEPQIEALRAGADVVVGTPGRLLDLSQQGHLQLGGLYV
MLBr_00811|M.leprae_Br4923          RFSVVSIYGGRAYEPQIEALQTGADVVVSTPGRLLDLCQQGHLQLSGLSV
TH_1004|M.thermoresistible__bu      KLSVVSIYGGRPYEPQIEALQKGADVVVGTPGRLLDLAQQNHLQLGGLSV
MAV_1401|M.avium_104                ---VLPIYGGSSYAVQLAGLKRGAHVVVGTPGRVIDHLERGTLDLSHVDY
                                       * .**** .*  *: .*: *..***.****::*  ::. *:*. :  

Mflv_4676|M.gilvum_PYR-GCK          LVLDEADEMLDLGFLPDIERILKQIP---AKRQAMLFSATMPDPIITLAR
Mvan_1791|M.vanbaalenii_PYR-1       LVLDEADEMLDLGFLPDIERILKQIP---AKRQAMLFSATMPDPIITLAR
MSMEG_1930|M.smegmatis_MC2_155      LVLDEADEMLDLGFLPDIERILQLTP---DSRQAMLFSATMPDPIITLAR
MAB_3531|M.abscessus_ATCC_1997      LVLDEADEMLDLGFLPDIERILALAPSADAGRQSMLFSATMPDPIITLAR
Mb3237|M.bovis_AF2122/97            LVLDEADEMLDLGFLPDIERILRQIP---ADRQSMLFSATMPDPIITLAR
Rv3211|M.tuberculosis_H37Rv         LVLDEADEMLDLGFLPDIERILRQIP---ADRQSMLFSATMPDPIITLAR
MMAR_1346|M.marinum_M               LVLDEADEMLDLGFLPDIERILRQIP---ADRQSMLFSATMPDPIITLAR
MUL_2533|M.ulcerans_Agy99           LVLDEADEMLDLGFLPDIERILRQIP---ADRQSMLFSATMPDPIITLAR
MLBr_00811|M.leprae_Br4923          LVLDEADEMLDLGFFPDIERLLGQIP---TDRQSMLFSATMPDPIITLAR
TH_1004|M.thermoresistible__bu      LVLDEADEMLDLGFLPDIERILRQIP---EKRQAMLFSATMPDPIITLAR
MAV_1401|M.avium_104                LVLDEADEMLTMGFAEEVDRILSETP---EYKQVALFSATMPPAIRKLTA
                                    ********** :**  :::*:*   *     :*  ******* .* .*: 

Mflv_4676|M.gilvum_PYR-GCK          TFMTQPTHIRAEGVQGSATHDTTEQFAYRAHALDKVEMVARILQAEGRGA
Mvan_1791|M.vanbaalenii_PYR-1       TFMTQPTHIRAEAPHSSATHDSTEQFAYRAHALDKVEMVARILQAEGRGA
MSMEG_1930|M.smegmatis_MC2_155      TFMNQPTHIRAEAPHSAATHDTTAQYAYRAHALDKVELVSRILQARGRGA
MAB_3531|M.abscessus_ATCC_1997      TFMNRPTHIRAEDPQASSVHDSTEQFVYRAHALDKIELVSRILQADGRGA
Mb3237|M.bovis_AF2122/97            TFMVRPTHIRAEAPHSSAVHDATEQFVYRAHALDKVELVSRVLQARDRGA
Rv3211|M.tuberculosis_H37Rv         TFMVRPTHIRAEAPHSSAVHDATEQFVYRAHALDKVELVSRVLQARDRGA
MMAR_1346|M.marinum_M               TFMIQPTHIRAEAPHSLAVHDTTEQFVYRAHALDKVELVTRVLQARERGA
MUL_2533|M.ulcerans_Agy99           TFMIQPTHIRAEAPHSLAVHDTTEQFVYRAHALDKVELVTRVLQARERGA
MLBr_00811|M.leprae_Br4923          TFMDQPIHIRAEAPHSLAVHDTTQQFVYRAHALDKVELISRILQARGRGA
TH_1004|M.thermoresistible__bu      TFMNQPTHIRAEAPQSSAVHDKTKQFVYRAHALDKVEMISRILQARGRGA
MAV_1401|M.avium_104                KYLHDPLEVSTKAKTTTAEN--ISQRYIQVAGPRKMDALTRVLEVEPFEA
                                    .::  * .: ::     : :    *   :. .  *:: ::*:*:.    *

Mflv_4676|M.gilvum_PYR-GCK          TMIFTRTKRTAQKVADELGERGFRVGAVHGDLGQSAREKALKGFRNGDVD
Mvan_1791|M.vanbaalenii_PYR-1       TMIFTRTKRTAQKVADELGERGFKVGAVHGDLGQAAREKALKSFRTGEVD
MSMEG_1930|M.smegmatis_MC2_155      TMVFTRTKRTAQKVSDELAERGFKVGAVHGDLGQGAREKALKSFRTGEID
MAB_3531|M.abscessus_ATCC_1997      TMIFTRTKRTAQKVSDELAERGFAVGAVHGDLGQIAREKALTSFRSGQIN
Mb3237|M.bovis_AF2122/97            TMIFTRTKRTAQKVADELTERGFAVGAVHGDLGQLAREKALKAFRTGGID
Rv3211|M.tuberculosis_H37Rv         TMIFTRTKRTAQKVADELTERGFAVGAVHGDLGQLAREKALKAFRTGGID
MMAR_1346|M.marinum_M               TMIFTRTKRTAQKVADELNERGFAVGAVHGDLGQVAREKALKSFRSGSVN
MUL_2533|M.ulcerans_Agy99           TMIFTRTKRTAQKVADELNERGFAVGAVHGDLGQVAREKALKSFRRGSVN
MLBr_00811|M.leprae_Br4923          TMIFTRTKRTAQKVTNELNERGFAVGAVHGDLGQIARENALEAFRTGNVD
TH_1004|M.thermoresistible__bu      TMIFTRTKRTAQKVADELAERGFAVGAVHGDLGQVAREKALKAFRAGEID
MAV_1401|M.avium_104                MIVFVRTKQATEEVAERLRARGFSAAAINGDIPQGQRERTVAALKDGGID
                                     ::*.***:::::*::.*  *** ..*::**: *  **.:: .:: * ::

Mflv_4676|M.gilvum_PYR-GCK          VLVATDVAARGIDIDDITHVINFQIPEDEQAYVHRIGRTGRAGKTGIAVT
Mvan_1791|M.vanbaalenii_PYR-1       VLVATDVAARGIDIDDITHVINFQIPEDEQAYVHRIGRTGRAGKTGIAVT
MSMEG_1930|M.smegmatis_MC2_155      VLVATDVAARGIDIDDVTHVINYQCPEDEQAYVHRIGRTGRAGKTGVAIT
MAB_3531|M.abscessus_ATCC_1997      VLVATDVAARGIDIDDVTHVINYQCPEDDKTYVHRIGRTGRAGRTGIAVT
Mb3237|M.bovis_AF2122/97            VLVATDVAARGIDIDDVTHVINYQCPEDEKMYVHRIGRTGRAGRTGVAVT
Rv3211|M.tuberculosis_H37Rv         VLVATDVAARGIDIDDVTHVINYQCPEDEKMYVHRIGRTGRAGRTGVAVT
MMAR_1346|M.marinum_M               VLVATDVAARGIDIDDVTHVINYQCPEDEKMYVHRIGRTGRAGRTGVAVT
MUL_2533|M.ulcerans_Agy99           VLVATDVAARGIDIDDVTHVINYQCPEDEKMYVHRIGRTGRAGRTGVAVT
MLBr_00811|M.leprae_Br4923          VLVATDVAARGIDIDDVTHVINYQCPEDEKMYVHRIGRTGRAGRTGVAVT
TH_1004|M.thermoresistible__bu      VLVATDVAARGIDIEDVTHVINYQIPEDEQAYVHRIGRTGRAGRTGVAIT
MAV_1401|M.avium_104                ILVATDVAARGLDVERISHVLNYDIPHDTESYVHRIGRTGRAGRSGTALL
                                    :**********:*:: ::**:*:: *.* : ************::* *: 

Mflv_4676|M.gilvum_PYR-GCK          LVDWDELPRWSMIDKALGLDTPDPAETYSNS-------------------
Mvan_1791|M.vanbaalenii_PYR-1       LVDWDELPRWSMIDKALGLDTPDPAETYSNS-------------------
MSMEG_1930|M.smegmatis_MC2_155      LVDWDELARWEMIDKALNLGNPDPAETYSSS-------------------
MAB_3531|M.abscessus_ATCC_1997      LVDWDDIARWQLIDKALGLGVPEPDETYSTS-------------------
Mb3237|M.bovis_AF2122/97            LVDWDELPRWSMIDQALGLGSPDPAETYSNS-------------------
Rv3211|M.tuberculosis_H37Rv         LVDWDELPRWSMIDQALGLGSPDPAETYSNS-------------------
MMAR_1346|M.marinum_M               LVDWDELPRWTMIDKALGLGSPDPAETYSSS-------------------
MUL_2533|M.ulcerans_Agy99           LVDWDELPRWTMIDKALGLGSPDPAETYSSS-------------------
MLBr_00811|M.leprae_Br4923          LVDWDELHRWETIDKALGLGTPDPAETYSNS-------------------
TH_1004|M.thermoresistible__bu      LVDWDELPRWEMIDKALNLGNPDPPETYSXXX------------------
MAV_1401|M.avium_104                FVSPRERHLLKAIEKATRQPLTEAELPTVEDVNAQRVAKFADSITAALGA
                                    :*.  :      *::*     .:.  .                       

Mflv_4676|M.gilvum_PYR-GCK          --PHLYDELNIPTEAGGSIGKPARSADKP--KREPREPRAERP-------
Mvan_1791|M.vanbaalenii_PYR-1       --PHLYEELNIPAEAGGSIGRPKRTADKE--PREPRE-RREKP-------
MSMEG_1930|M.smegmatis_MC2_155      --PHLYEDLDIPTDATGTVGKPAKRATKASDEDEHRISSADRP-------
MAB_3531|M.abscessus_ATCC_1997      --PHLFTELNIPADVTGSIGEKFSGGPKR---REPRGERAEGE-------
Mb3237|M.bovis_AF2122/97            --PHLYAELAIPATAGGTVGPARKSQGRR--RDT----DCDGQ----KTA
Rv3211|M.tuberculosis_H37Rv         --PHLYAELAIPATAGGTVGPARKSQGRR--RDT----DCDGQ----KTA
MMAR_1346|M.marinum_M               --PHLYTELSIPTDAAGTVGPPSKSGSKP--RTTEKQDDQQGE----KSG
MUL_2533|M.ulcerans_Agy99           --PHLYTELSIPTDAAGTVGPPSKSGSKP--RTTEKQDDQQGE----KSG
MLBr_00811|M.leprae_Br4923          --PHLYTELAIPAEASGTVGTPRKAQVKR--RKTDRDGDKSGTSAQAAKA
TH_1004|M.thermoresistible__bu      --PSTTGAADSRAGGTWAAASAPAAATAAGSGNALVTIDAASP---ISVT
MAV_1401|M.avium_104                PGIDLFRKLVQDYEREHDVPMADIAAALAVQSRDGEEFLMAPEPPRERRE
                                                                                      

Mflv_4676|M.gilvum_PYR-GCK          -ARDRTR--RRTRGGQSVSGHPEGTPDAADTSSSEASDSDSAGDGAPRPA
Mvan_1791|M.vanbaalenii_PYR-1       -TSNRSR--RRTRGGKSVGGHPEGTTEQAAPEADNAG--AEAPEGAASPA
MSMEG_1930|M.smegmatis_MC2_155      -ARTRTRSRRRTRGGKPLTGHPESHPEAHPESASAAPEDTEAAPAGESEA
MAB_3531|M.abscessus_ATCC_1997      -KPKRTRTRRRTRAGQPTD---ESAAEAPAPEAATADGDQQAPAR-----
Mb3237|M.bovis_AF2122/97            QHARNTPRRRRTRGGKPVTGHPGTNP-ISSPIVGGDATSEPGSGTASDSG
Rv3211|M.tuberculosis_H37Rv         QHARNTPRRRRTRGGKPVTGHPGTNP-ISSPIVGGDATSEPGSGTASDSG
MMAR_1346|M.marinum_M               RARSDAGRRRRTRGGKPVTGHPATTP-VAS----GETATETGSGSGASS-
MUL_2533|M.ulcerans_Agy99           RARSDAGRRRRTRGGKPVTGHPATTP-VAS----GETATETGSGFGASS-
MLBr_00811|M.leprae_Br4923          ARTSNSVQRHRIRGGQPVTGHPTNNPSADSLATNGKVVAETLPNSSSGS-
TH_1004|M.thermoresistible__bu      LGGAAANCCTMSRHGTPGLGWPAAAAVNNAVGDQRATTATALPANRLILL
MAV_1401|M.avium_104                RHTERRERTEKPRSTRPLATYRIAVGKRHKIGPGAIVGAIANEGGLHRSD
                                                *   .                                 

Mflv_4676|M.gilvum_PYR-GCK          ------------------------RRRRRRRPNKATAA------GTSAGT
Mvan_1791|M.vanbaalenii_PYR-1       ------------------------RRRRRRRPSKAAAA------GSN---
MSMEG_1930|M.smegmatis_MC2_155      G-------------------EQTTRRRRRRRPRKTEAA------TAG---
MAB_3531|M.abscessus_ATCC_1997      ------------------------RRRRRRRPNATAAT------TASA--
Mb3237|M.bovis_AF2122/97            SDVVSG-------SRSGNGEAARRRRRRRRRPTHAQDG-----FAARAN-
Rv3211|M.tuberculosis_H37Rv         SDVVSG-------SRSGNGEAARRRRRRRRRPTHAQDG-----FAARAN-
MMAR_1346|M.marinum_M               --------------PSGN-AGATRRRRRRRKPAGVQDN-----AAASAN-
MUL_2533|M.ulcerans_Agy99           --------------PSGN-AGATRRRRRRRKPAGVQDN-----AAASAN-
MLBr_00811|M.leprae_Br4923          --------------PSTN----VRRRRHRRKPTEVAENGLDKNLAVQAN-
TH_1004|M.thermoresistible__bu      P----------------------IAFRRSIVPLATARK------------
MAV_1401|M.avium_104                FGHIAIGPDFSLVELPAKLPKSTLKRLEQTRISGVLINLQPDRAAAKARG
                                                               .      .               

Mflv_4676|M.gilvum_PYR-GCK          SAGTN-------
Mvan_1791|M.vanbaalenii_PYR-1       ------------
MSMEG_1930|M.smegmatis_MC2_155      ------------
MAB_3531|M.abscessus_ATCC_1997      ------------
Mb3237|M.bovis_AF2122/97            ------------
Rv3211|M.tuberculosis_H37Rv         ------------
MMAR_1346|M.marinum_M               ------------
MUL_2533|M.ulcerans_Agy99           ------------
MLBr_00811|M.leprae_Br4923          ------------
TH_1004|M.thermoresistible__bu      ------------
MAV_1401|M.avium_104                RDGGKPRRKYGG