For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0898 (csp)

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1805808 - 1806290
length: 161

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0898csp-100% (161)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1521-4e-1338.46% (104) POSSIBLE CONSERVED TRANSMEMBRANE ALANINE AND GLYCINE RICH

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3841-8e-4958.13% (160) hypothetical protein Mb3841
M. gilvum PYR-GCKMflv_1157-8e-6570.62% (160) LGFP repeat-containing protein
M. tuberculosis H37RvRv3811-8e-4958.13% (160) hypothetical protein Rv3811
M. leprae Br4923MLBr_01002-8e-1030.48% (105) hypothetical protein MLBr_01002
M. abscessus ATCC 19977MAB_0168c-3e-3343.72% (183) putative N-acetymuramoyl-L-alanine amidase
M. marinum MMMAR_5375-3e-4857.50% (160) hypothetical protein MMAR_5375
M. avium 104MAV_0206-7e-4755.00% (160) N-acetylmuramoyl-L-alanine amidase
M. smegmatis MC2 155MSMEG_6406-2e-6371.15% (156) N-acetylmuramoyl-L-alanine amidase
M. ulcerans Agy99MUL_4995-2e-4655.62% (160) hypothetical protein MUL_4995
M. vanbaalenii PYR-1Mvan_5652-1e-6772.50% (160) LGFP repeat-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3841|M.bovis_AF2122/97            --------------------MAATVVIVAWIANRPPA------SSHEPSP
Rv3811|M.tuberculosis_H37Rv         --------------------MAATVVIVAWIANRPPA------SSHEPSP
MMAR_5375|M.marinum_M               ------MPSRSRAPTMLLTAIAATVVIVSWVLTRPPP------STHEQPS
MUL_4995|M.ulcerans_Agy99           ---------------MLLTAIAATVVIVSWVLTRPPP------STHEQPS
MAV_0206|M.avium_104                -------MSRSRAPTTLLTAIAATVVLVSWVGDATRDR-----GAAGAPP
Mflv_1157|M.gilvum_PYR-GCK          ------MLYPRHAPSVLFTALAATVMLLPWAISGIPD-------GDEKPT
Mvan_5652|M.vanbaalenii_PYR-1       ------MLYRRPAPSILFTALAATVVMLPWAISGGPD-------GDDSPA
MSMEG_6406|M.smegmatis_MC2_155      ------MQSRRPAPSILFTAIAATLIVVPWALSGTGD-------EHHNPA
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      MRVSKMPVRRQLALAVAATATVMTVSVVDHIKSGQAEETAITSQSLQNAA
MLBr_01002|M.leprae_Br4923          ----MSKRVRRALANTATTAVVTVLLAPVVTASPTGDADDAITAAWHKAG
                                                                                      

Mb3841|M.bovis_AF2122/97            TPNTQLAEQPLIGLGGGVTVRELTQDTPFSLVALTG-DLAGTSARVRAKR
Rv3811|M.tuberculosis_H37Rv         TPNTQLAEQPLIGLGGGVTVRELTQDTPFSLVALTG-DLAGTSARVRAKR
MMAR_5375|M.marinum_M               AQDTRLVEQPLVGLGGGVTVRQLTQDEPFSLVALTG-DLVGTSARMRARQ
MUL_4995|M.ulcerans_Agy99           AQDTRLVEQPLVGLGGGVTVRQLTQDEPFSLVALTG-DLVGTSARMRARQ
MAV_0206|M.avium_104                ARGTQLTEQPLIGLGAGVTVREISQQTPFSLVALTG-DLAGTSTRVRARR
Mflv_1157|M.gilvum_PYR-GCK          AGAPLLVQQPLTDLGGGETIRELHQDTPFSMVALTSADLTGTSARVRAKK
Mvan_5652|M.vanbaalenii_PYR-1       MPAPQLAQQPLADLGGGESIRELHQDTPFSMVALTSEDFAGTSARVRAKK
MSMEG_6406|M.smegmatis_MC2_155      ADAPSLTQQPLDDLGGGETIREIHQDEPFSLVALTAHDLDGTSARIRAKK
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      THDVLTSEVGLPGPSTPATVHDIQQADSFSLIAVRGEDLSSLDVSVRAQQ
MLBr_01002|M.leprae_Br4923          GDNSVLGAKKGEVYPLGDGFAQNFASGKLFFTTATGAKLLYGPVLGKYES
                                                                                      

Mb3841|M.bovis_AF2122/97            PDGDWGPWYQTEYETEPRDPAGTDGSVELGGLNPGP---RSTDPVFVGTT
Rv3811|M.tuberculosis_H37Rv         PDGDWGPWYQTEYETEPRDPAGTDGSVELGGLNPGP---RSTDPVFVGTT
MMAR_5375|M.marinum_M               SDGSWGPWYQAEYETAAPDEQG-AGAPATAGTSERP---RSTEPVFVGTT
MUL_4995|M.ulcerans_Agy99           SDGSWGPWYQAEYETAAPDEQG-AGAPATAGTSERP---RSTEPVFVGTT
MAV_0206|M.avium_104                RDGSWGPWYQTEYETAAPDPGH------AGEATEGP---RGTDPVFVGTT
Mflv_1157|M.gilvum_PYR-GCK          DDGSWGQWYDVEPLEG------------VGADTPSPGGIRGTDPVFVGRT
Mvan_5652|M.vanbaalenii_PYR-1       DDGSWGPWYEAEPLEG------------VGADLPGP---RGTEPVFVGRT
MSMEG_6406|M.smegmatis_MC2_155      ADGSWGPWYEAEALDG------------VGADTPGP---RGTDPVFVGRT
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      TDGSWGQWYELDPVESGDP---------AAEHKGIP---AATEPVFVGST
MLBr_01002|M.leprae_Br4923          LGGPVNSDLGFPIIDEVPG--------LAGPDSRVSIFAASDNPVIFWTP
                                                                                      

Mb3841|M.bovis_AF2122/97            TTVQVAVTRPIDAPITQPPAGRPPNDLLDSGLGYRPATKEQPFGQNISAI
Rv3811|M.tuberculosis_H37Rv         TTVQVAVTRPIDAPITQPPAGRPPNDLLDSGLGYRPATKEQPFGQNISAI
MMAR_5375|M.marinum_M               NTVEIAVTRPIDAPVTQPPPTGEP-EPVD--LGYRPATKELPFGQNISAV
MUL_4995|M.ulcerans_Agy99           NTVEIAVTRSIDAPVTQPPPTGEP-EPLD--LGYRPATKELPFGQNISAV
MAV_0206|M.avium_104                TTVQIAVTRPLDAPATQPPP-----RPADD-LGYRPASREQPFGQNISAV
Mflv_1157|M.gilvum_PYR-GCK          TTVQIAVTRPDDAPATRPAAPAAPAPTGPA-LGYVPANVEQPLAENVTAV
Mvan_5652|M.vanbaalenii_PYR-1       TTVQVAVTRPSDAPPIGPAA-AAHKPDGPA-LGYIPANVESPLPQNITAV
MSMEG_6406|M.smegmatis_MC2_155      NTVQIAITRPENAAPTAPAPKNKDDKNKPD-LGYRPATVQQPLGQNVTAV
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      HSAQVAVQPKYGANVKSPKTDNRR-TPADAGLGYRPASIEQPLTTGLDAI
MLBr_01002|M.leprae_Br4923          DHGAFVVRGALNAAWDKLGSSAGVLGVPVADESFDGEVISQKFSGGAVFW
                                                                                      

Mb3841|M.bovis_AF2122/97            LISPPQAPPGTQWTPP-----TAVTMAGQPPAIISRAEWGADESLRCETP
Rv3811|M.tuberculosis_H37Rv         LISPPQAPPGTQWTPP-----TAVTMAGQPPAIISRAEWGADESLRCETP
MMAR_5375|M.marinum_M               LISPPQAPAGTHWTPP-----TGVTMPGQAPPIISRADWGADEALRCESP
MUL_4995|M.ulcerans_Agy99           LISPPQAPAGTHWTPP-----TGVTMPGQAPPIISRADWGADEALRCESP
MAV_0206|M.avium_104                LISPPQAPSETHWTPP-----SGVVMPGQAPPIISRAEWGADESLRCGSP
Mflv_1157|M.gilvum_PYR-GCK          LISPPEAPPDLGPLP------NAATPAGQPPRIINRVEWGADEGMRCGEP
Mvan_5652|M.vanbaalenii_PYR-1       LISPPQAPPDLVPLP------NAATPAGQPPRIINRVEWGADEGMRCGEP
MSMEG_6406|M.smegmatis_MC2_155      LISPPQAPADIGPLP------TAVTAPGVPPHIIGRAQWGADESMRCP-A
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      LISPKLAPPDAARFEERWS--APVALPQAGPRIITRAQWGANESDRCP-P
MLBr_01002|M.leprae_Br4923          NKKSSEFTTEPTALAEQLTGLLVATDPTTAISMAWRAAGGVSGPLGPKQG
                                                                                      

Mb3841|M.bovis_AF2122/97            EYDRGVRAAVVHHTAGSNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA
Rv3811|M.tuberculosis_H37Rv         EYDRGVRAAVVHHTAGSNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA
MMAR_5375|M.marinum_M               EYDRAVRAAVVHHTAGSNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA
MUL_4995|M.ulcerans_Agy99           EYDRTVRAAVVHQTAGSNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA
MAV_0206|M.avium_104                QYDNGIRAAVVHHTAGNNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA
Mflv_1157|M.gilvum_PYR-GCK          RYDNKIRAGVLHHTAGSNEYGPGDS-AGIIRSIYEYHTRTLG---WCDIA
Mvan_5652|M.vanbaalenii_PYR-1       RYDTRIRAGVVHHTAGSNEYTPEDS-AGIVRSIYEYHTRTLG---WCDIA
MSMEG_6406|M.smegmatis_MC2_155      VYDAGIRAGIVHHTAGSNDYAPEDS-AGIVRSIYEYHTRTLG---WCDIA
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      VYNRDVRAGVVHHTAGSNNYSPYDS-AAIIRAIYAYHTKTLK---WCDIA
MLBr_01002|M.leprae_Br4923          GQHPIGADGIIQDFAGGKVFFSKATGANAVENDILAKYESLGGPVGSDLG
                                                                                      

Mb3841|M.bovis_AF2122/97            YNALVDKYG--------------------------------------QVF
Rv3811|M.tuberculosis_H37Rv         YNALVDKYG--------------------------------------QVF
MMAR_5375|M.marinum_M               YNALVDKYG--------------------------------------QIF
MUL_4995|M.ulcerans_Agy99           YNALVDKYG--------------------------------------QIF
MAV_0206|M.avium_104                YNALVDKYG--------------------------------------QVF
Mflv_1157|M.gilvum_PYR-GCK          YNAMVDKYG--------------------------------------QVF
Mvan_5652|M.vanbaalenii_PYR-1       YNAMVDKYG--------------------------------------QVF
MSMEG_6406|M.smegmatis_MC2_155      YNALVDKYG--------------------------------------QVF
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      YNVLVDKYG--------------------------------------QIF
MLBr_01002|M.leprae_Br4923          FPAANEGDGGIVTSSRIAIFSAADKPVIFWTPDHGAFVVRGAMKAAWDKL
                                                                                      

Mb3841|M.bovis_AF2122/97            EGSAGGLTKPVEGFHTGG--FNRNTWGVAMIGNFDDVAPTPIQIRTVGRL
Rv3811|M.tuberculosis_H37Rv         EGSAGGLTKPVEGFHTGG--FNRNTWGVAMIGNFDDVAPTPIQIRTVGRL
MMAR_5375|M.marinum_M               EGSAGGLTKPVEGFHTGG--FNRDTWGVAMIGNFDDVAPTPLQIRAVGRL
MUL_4995|M.ulcerans_Agy99           EGSAGGLTKPVEGFHTGG--FNRDAWGVAMIGNFDDVAPTPLQIRAVGRL
MAV_0206|M.avium_104                EGSAGGLTKAVEAFHTGG--FNRNTWGVAMIGNFDDVPPTPVQLRAVGRL
Mflv_1157|M.gilvum_PYR-GCK          EGRAGGMTRPVEGAHTGG--FNHNTWGVAMLGNFEAVPPTPIQLRNTSRL
Mvan_5652|M.vanbaalenii_PYR-1       EGRAGGMNRPVEGAHTGG--FNHNTWGVAMLGNFDVVPPTPIQLRNTATL
MSMEG_6406|M.smegmatis_MC2_155      EGRAGGMDRPVEGAHTGG--FNRDTWGVAMMGNFDAVPPTPIQLRTTGRL
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      EGRFGGITNNVQGAHTGG--FNEHSWGIALIGDFTRDEPSPAMLQAAGRI
MLBr_01002|M.leprae_Br4923          KGPNGKLGVPVADQSVDGNVISQRFIGGKISWNRANNTFTADPANLASLL
                                                                                      

Mb3841|M.bovis_AF2122/97            LGWRLGMDDVDPRSMVDLQSAGSS--------------------------
Rv3811|M.tuberculosis_H37Rv         LGWRLGMDDVDPRSMVDLQSAGSS--------------------------
MMAR_5375|M.marinum_M               LGWRLGIAEVDPKSMVELESTGSS--------------------------
MUL_4995|M.ulcerans_Agy99           LGWRLGIAEVDPKSMVELESTGSS--------------------------
MAV_0206|M.avium_104                LGWRLGMDGVDPKGTVQLESAGSH--------------------------
Mflv_1157|M.gilvum_PYR-GCK          LGWVLGQSGVDPLGSVVLPSEGGS--------------------------
Mvan_5652|M.vanbaalenii_PYR-1       LGWVLGQAGVDPLATVVMPSEGGS--------------------------
MSMEG_6406|M.smegmatis_MC2_155      LGWRLGLDRIDPHGTVVLASEGGS--------------------------
TH_0898|M.thermoresistible__bu      --------------------------------------------------
MAB_0168c|M.abscessus_ATCC_199      LGWRLRLAGVDPRGQVDLASEGGP--------------------------
MLBr_01002|M.leprae_Br4923          SGLQVSEQSQPSELAMLFHAKKSTGHWWWLVAAVAVLLVIVMFVLLALGW
                                                                                      

Mb3841|M.bovis_AF2122/97            --------YTTFPGGAIARLPAIFTHRDVGNTDCPGNAAYAVMDEIRDIA
Rv3811|M.tuberculosis_H37Rv         --------YTTFPGGAIARLPAIFTHRDVGNTDCPGNAAYAVMDEIRDIA
MMAR_5375|M.marinum_M               --------YTTVPGGAIAKLPAIFTHRDVGNTDCPGNAAYALMDEIREIA
MUL_4995|M.ulcerans_Agy99           --------YTTVPGGAIAKLPAIFTHRDVGNTDCPGNAAYALMDEIREIA
MAV_0206|M.avium_104                --------YTTYAAGTVATLPTIFTHRDVGNTDCPGNAAYALMDEIRDIA
Mflv_1157|M.gilvum_PYR-GCK          --------FTKFPFGAPTTLPAIFTHRDVGNTECPGAAAYALLPEVRNIA
Mvan_5652|M.vanbaalenii_PYR-1       --------FTKFPFGASPTLPTIFTHRDVGNTECPGNAAYALMGQIRDIA
MSMEG_6406|M.smegmatis_MC2_155      --------FTHFPRGATPTLPAIFTHRDVGNTDCPGNAAYAEMGRLRDIA
TH_0898|M.thermoresistible__bu      ------------------------------------------MDRIRQIA
MAB_0168c|M.abscessus_ATCC_199      --------FTTVPGGKVVTLPTIFTHRDVGNTECPGEAAYRLIPRLRDIA
MLBr_01002|M.leprae_Br4923          RRRRTAHDIVADSHDHDMDVGMDFGYKAAVDGQCTYDAESGTEHPVRDVE
                                                                                 :*:: 

Mb3841|M.bovis_AF2122/97            AHFN-----DPP--EELIKALEGGAIY------QRWQALGGMNSALGAPT
Rv3811|M.tuberculosis_H37Rv         AHFN-----DPP--EELIKALEGGAIY------QRWQALGGMNSALGAPT
MMAR_5375|M.marinum_M               SHFN-----DPP--EELLKSLEGGAIY------QRWQELGAMNSVLGAPT
MUL_4995|M.ulcerans_Agy99           SHFN-----DPP--EELLKSLEGGATY------QRWQELGAMNSVLGAPT
MAV_0206|M.avium_104                AHVN-----DPP--EELIKALQGGAIY------AHWQEIGGMNSVLGAPT
Mflv_1157|M.gilvum_PYR-GCK          ARFN-----DPPGPEQLAETLRGGAIH------AKWESLGGMNSYLGRPT
Mvan_5652|M.vanbaalenii_PYR-1       ARFN-----DPPGPEQLAETLRGGAIH------AKWEALGGMNSYLGRPT
MSMEG_6406|M.smegmatis_MC2_155      ARFN-----QPPGPEELAEQMRGGAIF------ARWESVGGPAGPLGNPT
TH_0898|M.thermoresistible__bu      ARFK-----EPPGPEDLADTLRGGAIH------ARWEAMGGMASVLGGPT
MAB_0168c|M.abscessus_ATCC_199      AGAAN---GEPP---DLVDSLRGGAIY------DTWTRLGSAESDLGAPT
MLBr_01002|M.leprae_Br4923          RGPTVSWLRGAQDATGLAQDARLGPAFGSELPSESEEPLGLEEDDPDAVD
                                              .     * .  . *. .           :*   .  .   

Mb3841|M.bovis_AF2122/97            SPEADAADGARYATFAKG-AMYWSPVTDAQPITG---------AIYEAWA
Rv3811|M.tuberculosis_H37Rv         SPEADAADGARYATFAKG-AMYWSPVTDAQPITG---------AIYEAWA
MMAR_5375|M.marinum_M               SPEADGADGARYATFAKG-AMYWSPTTGAQPVTG---------AIYDAWA
MUL_4995|M.ulcerans_Agy99           SPEADGAGGARYATFAKG-VMYWSSTTGAQPVTG---------AIYDAWA
MAV_0206|M.avium_104                APEDSAADDARFVTFVRG-AMYWSPQTGAQPVTG---------AIYDAWG
Mflv_1157|M.gilvum_PYR-GCK          SPEASGLGATRYVTFEHG-AVYWSPETGAEPVTG---------ELYKAWG
Mvan_5652|M.vanbaalenii_PYR-1       SPEASGEGATRYVTFEHG-AVYWSPESGAEPVTG---------ELYNAWG
MSMEG_6406|M.smegmatis_MC2_155      SPEAAAEGEARYATFERG-AIYWSPVTGAQPLTG---------AIYEAWG
TH_0898|M.thermoresistible__bu      SPETIGANGSRYVTFEKG-AIYWSPETGAQPLTG---------AIYAVWG
MAB_0168c|M.abscessus_ATCC_199      SVEQQAVGEARFATFRNG-AMYFSPGTGAHPVVG---------AIYHAWA
MLBr_01002|M.leprae_Br4923          TDSMPALSDADFPYAALSDAAHWDADAAEVVATDNSSVATDNSSLLETAA
                                    : .  . . : :     . . ::.. :     ..          :  . .

Mb3841|M.bovis_AF2122/97            SQSYERGPLGLPTSAEIQEPLQITQNFQHGTLNFERLTGNVTEVVDGITT
Rv3811|M.tuberculosis_H37Rv         SQSYERGPLGLPTSAEIQEPLQITQNFQHGTLNFERLTGNVTEVVDGITT
MMAR_5375|M.marinum_M               SLSYERGPLGLPTSAEIQEPLRITQNFQHGVLNFQRLTGNVSEVVNGITT
MUL_4995|M.ulcerans_Agy99           SLSYERGPLGLPTSAEIQEPLRITQNFQHGVLNFQRLTGNVSEVVNGITT
MAV_0206|M.avium_104                SQSYERGPLGLPTSAEIQEPLQITQNFQHGTLNYERLTGNVTEVLDGITT
Mflv_1157|M.gilvum_PYR-GCK          ALGFERGALGLPTSAEIAEPLWIVQNFQHGTLNFDREKGTVTRVTDGVPV
Mvan_5652|M.vanbaalenii_PYR-1       SLGFERGALGLPTSAEIPEPLWIVQNFQHGTLNFDRETGAVTRVIDGVPV
MSMEG_6406|M.smegmatis_MC2_155      RLGFERGALGLPTSGEIHEPLWIKQNFQHGTLNFDREKHTVVRVIDGVPQ
TH_0898|M.thermoresistible__bu      SLGFERGLLGLPTSAEIHEPQWIVQNFQHGTLNFDRENGRVVRVVDGVEL
MAB_0168c|M.abscessus_ATCC_199      ETDFERGPLGLPVTDEIGEPNIIVQNFQNGSLIYDRASGRVSSVINGETR
MLBr_01002|M.leprae_Br4923          DTEVSTGRHAAVDMADAMDASFPGVTVPRMLFRPSPTLRPTIHLPLDDPY
                                        . *  .     :  :.     .. .  :  .     .  :  .   

Mb3841|M.bovis_AF2122/97            PLATRPPSGPTVPPEHFTLPTHPIT------------------------
Rv3811|M.tuberculosis_H37Rv         PLATRPPSGPTVPPEHFTLPTHPIT------------------------
MMAR_5375|M.marinum_M               PLATKPPSGPMVPPEHFSLPIHPIIP-----------------------
MUL_4995|M.ulcerans_Agy99           PLATKPPSGPMVPPEHFSLPIHPIIP-----------------------
MAV_0206|M.avium_104                PLATQLPSGPTVPAEHFSLPTHPAAT-----------------------
Mflv_1157|M.gilvum_PYR-GCK          ELPP--ADLNPVQLERFTPPSNPV-------------------------
Mvan_5652|M.vanbaalenii_PYR-1       ELPPPGADSTPVQLERFTPPSNPA-------------------------
MSMEG_6406|M.smegmatis_MC2_155      ELPPAAPDDQPVQLERFTPIA----------------------------
TH_0898|M.thermoresistible__bu      EIPLPEPDAYPVQLERFTPAINP--------------------------
MAB_0168c|M.abscessus_ATCC_199      EILGVAPVAQNALPEQFSAPAAPAAPPPPAPAPPPPPPPVEQFAPAN--
MLBr_01002|M.leprae_Br4923          QVPDGYPIKASPRFGLYYTPASELYHDTLAEVWLANEEIAQVNGFIKAD
                                     :    .         :