For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0827 | sigB | - | 100% (337) | RNA POLYMERASE SIGMA FACTOR SIGB |
| M. thermoresistible (build 8) | TH_0829 | sigB | 1e-44 | 66.91% (139) | RNA POLYMERASE SIGMA FACTOR SIGB |
| M. thermoresistible (build 8) | TH_0997 | rne | 9e-09 | 25.82% (182) | POSSIBLE RIBONUCLEASE E RNE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2722 | sigA | 1e-106 | 60.50% (357) | RNA polymerase sigma factor |
| M. gilvum PYR-GCK | Mflv_3939 | - | 1e-101 | 62.72% (346) | RNA polymerase sigma factor |
| M. tuberculosis H37Rv | Rv2703 | sigA | 1e-106 | 60.50% (357) | RNA polymerase sigma factor |
| M. leprae Br4923 | MLBr_01022 | rpoT | 1e-107 | 62.18% (349) | RNA polymerase sigma factor |
| M. abscessus ATCC 19977 | MAB_3009 | - | 2e-97 | 62.27% (326) | RNA polymerase sigma factor |
| M. marinum M | MMAR_2011 | sigA | 1e-104 | 61.49% (348) | RNA polymerase sigma factor SigA |
| M. avium 104 | MAV_3595 | - | 1e-100 | 62.12% (330) | RNA polymerase sigma factor |
| M. smegmatis MC2 155 | MSMEG_2758 | - | 1e-105 | 63.24% (340) | RNA polymerase sigma factor |
| M. ulcerans Agy99 | MUL_3341 | sigA | 1e-104 | 61.49% (348) | RNA polymerase sigma factor |
| M. vanbaalenii PYR-1 | Mvan_2461 | - | 1e-101 | 63.41% (328) | RNA polymerase sigma factor |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2011|M.marinum_M --------------------------------------------------
MUL_3341|M.ulcerans_Agy99 --------------------------------------------------
Mb2722|M.bovis_AF2122/97 --------------------------------------------------
Rv2703|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01022|M.leprae_Br4923 MEQSRRVPPLQWLSAVARPIARVLTLISTPTFDIADTFGYACPNPPEVSP
MAV_3595|M.avium_104 --------------------------------------------------
Mflv_3939|M.gilvum_PYR-GCK ------------------------------------------MCAPTTRT
Mvan_2461|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2758|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3009|M.abscessus_ATCC_1997 --------------------------------------------------
TH_0827|M.thermoresistible__bu --------------------------------------------------
MMAR_2011|M.marinum_M -----MAATKASPETGEPVKRTATKSPAK------AGAKR-PTKTANGAA
MUL_3341|M.ulcerans_Agy99 -----MAATKASPETGEPVKRTATKSPAK------AGAKR-PTKTANGAP
Mb2722|M.bovis_AF2122/97 -----MAATKASTATDEPVKRTATKSPAASASGAKTGAKRTAAKSASGSP
Rv2703|M.tuberculosis_H37Rv -----MAATKASTATDEPVKRTATKSPAASASGAKTGAKRTAAKSASGSP
MLBr_01022|M.leprae_Br4923 TEGVYVVATKTSPATGQPVKRTATKTPAT-------PAKRSTTKAANGSA
MAV_3595|M.avium_104 ------------------MKRTATKSPSS-------PAKRPAAKAANGSA
Mflv_3939|M.gilvum_PYR-GCK TERVYVAATKASAATDEPVKRTAAKAPAK-------------------KA
Mvan_2461|M.vanbaalenii_PYR-1 -----MAATKASPATEEPVKRTAAKAPAK-------------------KA
MSMEG_2758|M.smegmatis_MC2_155 -----MAATKASPATEEPVKRTATKTPAK-------------------KA
MAB_3009|M.abscessus_ATCC_1997 -----MAATKAAPVTQATAETPSNTTATK-------------------AA
TH_0827|M.thermoresistible__bu ---VYVAATEASPATDEP-KRTATKTPAKK--AAATKSASGTTKSGNGSA
: .: .:.: .
MMAR_2011|M.marinum_M PAKRAAKTTG-------QADDATTGDAPK-KTRPSAR--GTKAARG----
MUL_3341|M.ulcerans_Agy99 PAKRAAKTPG-------QADDATTGDAPK-KTRPSAR--GTKAARG----
Mb2722|M.bovis_AF2122/97 PAKRATKPAARSVKPASAPQDTTTSTIPKRKTRAAAKSAAAKAPSARGHA
Rv2703|M.tuberculosis_H37Rv PAKRATKPAARSVKPASAPQDTTTSTIPKRKTRAAAKSAAAKAPSARGHA
MLBr_01022|M.leprae_Br4923 PTKRATSTASRATKSTTPPKASGASDAAK-KARTSVKSVDTKAPSAQDHT
MAV_3595|M.avium_104 PAKRATKTASRSAKS----EAGAAAEPAK-KTRSSAKGADAKAPSGRG--
Mflv_3939|M.gilvum_PYR-GCK PAKKATK-------------------ATKPRAAKSADAPATRGRAK----
Mvan_2461|M.vanbaalenii_PYR-1 PAKKAAKSAP--------------AKATKPRAAKSADAPATRGRAK----
MSMEG_2758|M.smegmatis_MC2_155 PAKRAAK---------------------SAAAKAGGKAPAKKAPAK----
MAB_3009|M.abscessus_ATCC_1997 PAKKAPA--------------------KAATKAPAKKAPAKKAPAK----
TH_0827|M.thermoresistible__bu PAKRAAKSSR-----------TKSESGSATKSRATKATKATKSTAT----
*:*:*. :.
MMAR_2011|M.marinum_M --TKAPGEGATDPDA------NLDTADDLDADPDIDVDSSDDLDLD--LD
MUL_3341|M.ulcerans_Agy99 --TKAPGEGATDPDA------NLDTADDLDADPDIDVDSSDDLDLD--LD
Mb2722|M.bovis_AF2122/97 TKPRAPKDAQHEAAT--DPEDALDSVEELDAEPDLDVEPGEDLDLD--AA
Rv2703|M.tuberculosis_H37Rv TKPRAPKDAQHEAAT--DPEDALDSVEELDAEPDLDVEPGEDLDLD--AA
MLBr_01022|M.leprae_Br4923 TKASAAKDTLNDPEATLNTLDSDATADDLDAEPDLDVEPSEDIDIDIEAA
MAV_3595|M.avium_104 --TKAAKGGPADP----DALDTDGAVEDLDTEPDLEGEPGEDLDID---T
Mflv_3939|M.gilvum_PYR-GCK ---KATAAEPGVVDD------ELTGTEVDATDD---IEPGEDL---VDDG
Mvan_2461|M.vanbaalenii_PYR-1 ---KATA--PGAVDD------DLAGSDVETGDDLVEAEPGDDLE--VEDT
MSMEG_2758|M.smegmatis_MC2_155 ---RAAKGTAAKPED------GVT-DDLEVTDD-LEAEPGEDLD--VEDT
MAB_3009|M.abscessus_ATCC_1997 ---AATKAPAKKAPA------KKAPAKKAAAKA---TDPALEPQGAADDA
TH_0827|M.thermoresistible__bu ---KATKSAAKAAGK-----TTRAKSGAANTRARTKKDADETLVDDVDAV
*. :.
MMAR_2011|M.marinum_M DLEDED-EAASDEAEGDDDSDEGDDAEDGDGAKAPAAAAPGTP--SDEEE
MUL_3341|M.ulcerans_Agy99 DLEDED-EAASDEAEGDDDSDEGDDAEYGDGAKAPAAAAPGTA--SDEEE
Mb2722|M.bovis_AF2122/97 DLNLDD-LEDDVAPDADDDLDSGD-DEDHEDLEAEAAVAPGQT-ADDDEE
Rv2703|M.tuberculosis_H37Rv DLNLDD-LEDDVAPDADDDLDSGD-DEDHEDLEAEAAVAPGQT-ADDDEE
MLBr_01022|M.leprae_Br4923 DLGLDD-LEDDDVVT---DIEPGE-TEDGE---ATAATKTDEASTDDDEE
MAV_3595|M.avium_104 DLNLDD-LEEDVAADDA-DIEPGD-AEEGEDEEAAAPKAAGATAADEDDE
Mflv_3939|M.gilvum_PYR-GCK DLELDD-IEVEDEATEDDDSDDEAAEADPVVATTKAAAKPAKE--ADDDS
Mvan_2461|M.vanbaalenii_PYR-1 DLVLDEELEVDDDTAVDGDSDDEDADEG-----APKAAKPAKD--GDDDG
MSMEG_2758|M.smegmatis_MC2_155 DLELDD-LDSDDDTAVEDEEEEADAATP--------AVATAKA--ADDD-
MAB_3009|M.abscessus_ATCC_1997 DIEPGD--DLDTDLADDADIEADLAEAA---------AEPEPE--AEADG
TH_0827|M.thermoresistible__bu DIEPDVAEDIDEADLDLTDIDVDDEDDA-----TEATAEDDDD--EDDDE
*: . : : : :
MMAR_2011|M.marinum_M IAEPSEKDKASGDFVWDEDESEALRQARKDAELTASADSVRAYLKQIGKV
MUL_3341|M.ulcerans_Agy99 IAEPSEKDKASGDFVWDEDESEALRQARKDAELTASADSVRAYLKQIGKV
Mb2722|M.bovis_AF2122/97 IAEPTEKDKASGDFVWDEDESEALRQARKDAELTASADSVRAYLKQIGKV
Rv2703|M.tuberculosis_H37Rv IAEPTEKDKASGDFVWDEDESEALRQARKDAELTASADSVRAYLKQIGKV
MLBr_01022|M.leprae_Br4923 IVEPTEKDKASGDFVWDEDESEALRQARKDAELTASADSVRAYLKQIGKV
MAV_3595|M.avium_104 IAEPSEKDKASGDFVWDEDESEALRQARKDAELTASADSVRAYLKQIGKV
Mflv_3939|M.gilvum_PYR-GCK LPEPSEKDKASGDFVWDEEESEALRQARKDAELTASADSVRAYLKQIGKV
Mvan_2461|M.vanbaalenii_PYR-1 VAEPSEKDKASGDFVWDEEESEALRQARKDAELTASADSVRAYLKQIGKV
MSMEG_2758|M.smegmatis_MC2_155 IDEPSEKDKASGDFVWDEEESEALRQARKDAELTASADSVRAYLKQIGKV
MAB_3009|M.abscessus_ATCC_1997 DDEPSEKDKASGDFVWDEEESEALRQARKDAELTASADSVRAYLKQIGKV
TH_0827|M.thermoresistible__bu IDEPSEKDKASGDFVWDEEESEALRQARKDAELTASADSVRAYLKQIGKV
**:*************:*******************************
MMAR_2011|M.marinum_M ALLNAEEEVELAKRIEAGLYATQLMAELTDRGEKLPAAQRRDMMWICRDG
MUL_3341|M.ulcerans_Agy99 ALLNAEEEVELAKRIEAGLYATQLMAELTDRGEKLPAAQRRDMMWICRDG
Mb2722|M.bovis_AF2122/97 ALLNAEEEVELAKRIEAGLYATQLMTELSERGEKLPAAQRRDMMWICRDG
Rv2703|M.tuberculosis_H37Rv ALLNAEEEVELAKRIEAGLYATQLMTELSERGEKLPAAQRRDMMWICRDG
MLBr_01022|M.leprae_Br4923 ALLNAEEEVELAKRIEAGLYATQLMTELSERGTKLPTAQRRDMMWICRDG
MAV_3595|M.avium_104 ALLNAEEEVELAKRIEAGLYATQLMSEMAERGEKLPAAQRRDMMWICRDG
Mflv_3939|M.gilvum_PYR-GCK ALLNAEEEVELAKRIEAGLYCTQLMAEFAEKGEKLTTAQRRDYMWICRDG
Mvan_2461|M.vanbaalenii_PYR-1 ALLNAEEEVELAKRIEAGLYATQLMAELADKGEKLPAAQRRDMMWICRDG
MSMEG_2758|M.smegmatis_MC2_155 ALLNAEEEVELAKRIEAGLYATQKLAELAEKGEKLPVQQRRDMQWICRDG
MAB_3009|M.abscessus_ATCC_1997 ALLNAEEEVELAKRIEAGLYATQIVTELTEKGEKLPAAQRRDMMWICRDG
TH_0827|M.thermoresistible__bu ALLNAEEEVDLAKRIEAGLFAAQKLAEYAEKGEKIPTQLRRDMQWICRDG
*********:*********:.:* ::* :::* *:.. *** ******
MMAR_2011|M.marinum_M DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
MUL_3341|M.ulcerans_Agy99 DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
Mb2722|M.bovis_AF2122/97 DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
Rv2703|M.tuberculosis_H37Rv DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
MLBr_01022|M.leprae_Br4923 DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
MAV_3595|M.avium_104 DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
Mflv_3939|M.gilvum_PYR-GCK DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
Mvan_2461|M.vanbaalenii_PYR-1 DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
MSMEG_2758|M.smegmatis_MC2_155 DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
MAB_3009|M.abscessus_ATCC_1997 DRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
TH_0827|M.thermoresistible__bu ERAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYT
:*************************************************
MMAR_2011|M.marinum_M KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
MUL_3341|M.ulcerans_Agy99 KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
Mb2722|M.bovis_AF2122/97 KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
Rv2703|M.tuberculosis_H37Rv KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
MLBr_01022|M.leprae_Br4923 KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
MAV_3595|M.avium_104 KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
Mflv_3939|M.gilvum_PYR-GCK KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
Mvan_2461|M.vanbaalenii_PYR-1 KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
MSMEG_2758|M.smegmatis_MC2_155 KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
MAB_3009|M.abscessus_ATCC_1997 KGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQ
TH_0827|M.thermoresistible__bu KGYKFSTYATWWX-------------------------------------
************
MMAR_2011|M.marinum_M DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
MUL_3341|M.ulcerans_Agy99 DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
Mb2722|M.bovis_AF2122/97 DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
Rv2703|M.tuberculosis_H37Rv DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
MLBr_01022|M.leprae_Br4923 DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
MAV_3595|M.avium_104 DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
Mflv_3939|M.gilvum_PYR-GCK DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
Mvan_2461|M.vanbaalenii_PYR-1 DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
MSMEG_2758|M.smegmatis_MC2_155 DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
MAB_3009|M.abscessus_ATCC_1997 DLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDF
TH_0827|M.thermoresistible__bu PRSRRSCPS-----------------------------------------
.*.. *.
MMAR_2011|M.marinum_M IEDSEAVVAVDAVSFTLLQDQLQSVLDTLSEREAGVVRLRFGLTDGQPRT
MUL_3341|M.ulcerans_Agy99 IEDSEAVVAVDAVSFTLLQDQLQSVLDTLSEREAGVVRLRFGLTDGQPRT
Mb2722|M.bovis_AF2122/97 IEDSEAVVAVDAVSFTLLQDQLQSVLDTLSEREAGVVRLRFGLTDGQPRT
Rv2703|M.tuberculosis_H37Rv IEDSEAVVAVDAVSFTLLQDQLQSVLDTLSEREAGVVRLRFGLTDGQPRT
MLBr_01022|M.leprae_Br4923 IEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRT
MAV_3595|M.avium_104 IEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRT
Mflv_3939|M.gilvum_PYR-GCK IEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRT
Mvan_2461|M.vanbaalenii_PYR-1 IEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRT
MSMEG_2758|M.smegmatis_MC2_155 IEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRT
MAB_3009|M.abscessus_ATCC_1997 IEDSEAVVAVDAVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRT
TH_0827|M.thermoresistible__bu --------------------------------------------------
MMAR_2011|M.marinum_M LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
MUL_3341|M.ulcerans_Agy99 LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
Mb2722|M.bovis_AF2122/97 LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
Rv2703|M.tuberculosis_H37Rv LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
MLBr_01022|M.leprae_Br4923 LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
MAV_3595|M.avium_104 LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
Mflv_3939|M.gilvum_PYR-GCK LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
Mvan_2461|M.vanbaalenii_PYR-1 LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
MSMEG_2758|M.smegmatis_MC2_155 LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
MAB_3009|M.abscessus_ATCC_1997 LDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
TH_0827|M.thermoresistible__bu ----------------------------------------