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M. thermoresistible (build 8) TH_0823 (dfp)

annotation: PROBABLE DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG DFP
coordinates: 1708007 - 1709197
length: 397

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0823dfp-100% (397)PROBABLE DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG DFP

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1426dfp1e-17782.56% (390) bifunctional phosphopantothenoylcysteine
M. gilvum PYR-GCKMflv_3738-0.083.42% (392) bifunctional phosphopantothenoylcysteine
M. tuberculosis H37RvRv1391dfp1e-17782.56% (390) bifunctional phosphopantothenoylcysteine
M. leprae Br4923MLBr_00543dfp1e-17077.44% (390) bifunctional phosphopantothenoylcysteine
M. abscessus ATCC 19977MAB_2821c-1e-17078.70% (399) bifunctional phosphopantothenoylcysteine
M. marinum MMMAR_2204dfp1e-17780.36% (392) DNA/pantothenate metabolism flavoprotein, Dfp
M. avium 104MAV_3383coaBC0.083.85% (390) bifunctional phosphopantothenoylcysteine
M. smegmatis MC2 155MSMEG_3054coaBC0.083.97% (393) bifunctional phosphopantothenoylcysteine
M. ulcerans Agy99MUL_1790dfp1e-17780.61% (392) bifunctional phosphopantothenoylcysteine
M. vanbaalenii PYR-1Mvan_2669-0.083.93% (392) bifunctional phosphopantothenoylcysteine

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3738|M.gilvum_PYR-GCK          -MAAK-------RIIVGVAGGIAAYKAATVVRQLTEAGHSVRVVPTESAL
Mvan_2669|M.vanbaalenii_PYR-1       -MERK-------RIIVGVAGGIAAYKAATVVRQLTEAGHSVRVVPTESAL
MSMEG_3054|M.smegmatis_MC2_155      MSARK-------RIVVGVAGGIAAYKACTVVRQLTEAGHSVRVVPTESAL
TH_0823|M.thermoresistible__bu      -----------------------------VVRQLSEAGHDVRVVPTESAL
MMAR_2204|M.marinum_M               -MDRK-------RIVVGVSGGIAAYKACTVVRQLTEAGHHVRVIPTESAL
MUL_1790|M.ulcerans_Agy99           -MDRK-------RIVVGVSGGIAAYKACTVVRQLTEAGHHVRVIPTESAL
MLBr_00543|M.leprae_Br4923          -MDCK-------RVVVGVSGGIAAYKACTVVRQLIDAGHEVRVIPTESAL
Mb1426|M.bovis_AF2122/97            MVDHKRIPK---QVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESAL
Rv1391|M.tuberculosis_H37Rv         MVDHKRIPK---QVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESAL
MAV_3383|M.avium_104                MYDRNRAFTRAARIVVGVSGGIAAYKACTVVRQLSEAGHSVRVIPTESAL
MAB_2821c|M.abscessus_ATCC_199      ----------MSRIIVGVGGGIAAYKACTVVRQLAEAGHSVRVVPTESAL
                                                                 ***** :*.* ***:******

Mflv_3738|M.gilvum_PYR-GCK          KFVGAATFEALSGNPVHTGVFEDVHEVPHVRIGQAADLVVVAPATADLLA
Mvan_2669|M.vanbaalenii_PYR-1       KFVGAATFEALSGNPVHTGVFAEVHEVPHVRIGQAADLVVVAPATADLLA
MSMEG_3054|M.smegmatis_MC2_155      RFVGAATFEALSGNPVHTGVFTDVHEVQHVRIGQQADLVVIAPATADLLA
TH_0823|M.thermoresistible__bu      KFVGAASFEALSGNPVHTGVFEDVPEVAHVRIGQQADLVVVAPATADLLA
MMAR_2204|M.marinum_M               RFIGAATFEALSGQPVHTGVFDDVPAVPHVQIGQQADLVVVAPATADLLA
MUL_1790|M.ulcerans_Agy99           RFIGAATFEALSGQPVHTGVFDDVPAVPHVQIGQQADLVVVAPATADLLA
MLBr_00543|M.leprae_Br4923          RFVGTATFEALSGQPVYTDVFDDIPAVSHVYLGKQADLVVVAPATADLLA
Mb1426|M.bovis_AF2122/97            RFVGAATFEALSGEPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLA
Rv1391|M.tuberculosis_H37Rv         RFVGAATFEALSGEPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLA
MAV_3383|M.avium_104                RFVGAATFEALSGQPVHTGVFNDVPEVPHVQLGKQADLVVVAPATADLLA
MAB_2821c|M.abscessus_ATCC_199      QFVGAATFEALSGEPARTGVFDDVPEVPHVRLGQDADLVVVAPATADLLS
                                    :*:*:*:******:*. *.** ::  * ** :*: *****:********:

Mflv_3738|M.gilvum_PYR-GCK          RAAVGRADDLLTATLLTARCPVLYAPAMHTEMWQHPATVDNVATLRRRGC
Mvan_2669|M.vanbaalenii_PYR-1       RATIGRADDLLTATLLTARCPVLYAPAMHTEMWLHPATCDNVATLRRRGS
MSMEG_3054|M.smegmatis_MC2_155      RAVAGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGA
TH_0823|M.thermoresistible__bu      RAAAGRADDLLTATLLTARCPVLFAPAMHTEMWFHPATVENVATLRRRGA
MMAR_2204|M.marinum_M               RAVAGRGDDLLTATLLTARCPVMFAPAMHTEMWLHPATVDNVATLRRRGA
MUL_1790|M.ulcerans_Agy99           RAVAGRGDDLLTATLLTARCPVMFAPAMHTEMWLHPATVDNVATLRRRGA
MLBr_00543|M.leprae_Br4923          RAVHGRADDLLTATLLTARCPIMFAPAMHTEMWLHPATVDNVATLRRRGA
Mb1426|M.bovis_AF2122/97            RAAAGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGA
Rv1391|M.tuberculosis_H37Rv         RAAAGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGA
MAV_3383|M.avium_104                RAVHGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGA
MAB_2821c|M.abscessus_ATCC_199      RAATGRADDLLTATLLTATCPVLFAPAMHTEMWLHPATQQNVATLRSRGA
                                    **. **.*********** **:::********* **** :****** **.

Mflv_3738|M.gilvum_PYR-GCK          VVMEPASGRLTGADTGPGRLPEAEEITTVAQLLLARGDALPHDLAGVRAL
Mvan_2669|M.vanbaalenii_PYR-1       IVMEPASGRLTGADTGPGRLPEAEEITTLAQLLLARNDALPYDLAGVKVL
MSMEG_3054|M.smegmatis_MC2_155      VVLEPASGRLTGADSGPGRLPEAEEITTLAQLLLERADALPYDMAGVKAL
TH_0823|M.thermoresistible__bu      VVLEPASGRLTGADSGAGRLPEAEEITTLAKLLLDRADALPYDLPGVKVV
MMAR_2204|M.marinum_M               VVLEPASGRLTGSDTGAGRLPEAEEITTLAQLLLERHDALPYDLAGRKVL
MUL_1790|M.ulcerans_Agy99           VVLEPASGRLTGSDAGAGRLPEAEEITTLAQLLLERHDALPYDLAGRKVL
MLBr_00543|M.leprae_Br4923          IVLEPASGRLTGTDSGAGRLPEAEEITTLAQLLLERHDALPYDLTGRKLL
Mb1426|M.bovis_AF2122/97            VVLEPATGRLTGADSGAGRLPEAEEITTLAQLLLERHDALPYDLAGRKLL
Rv1391|M.tuberculosis_H37Rv         VVLEPATGRLTGADSGAGRLPEAEEITTLAQLLLERHDALPYDLAGRKLL
MAV_3383|M.avium_104                VVLEPAAGRLTGTDSGSGRLPEAEEITTLAHLLLERHDALPYDLAGCKML
MAB_2821c|M.abscessus_ATCC_199      VVLEPASGRLTGADTGPGRLPEAEEITTLAQLLLARPDALPHDLAGVRVL
                                    :*:***:*****:*:*.***********:*:*** * ****:*:.* : :

Mflv_3738|M.gilvum_PYR-GCK          VTAGGTREPIDPVRFIGNRSSGKQGYAVARVMAQRGADVTLIAGNTAGLI
Mvan_2669|M.vanbaalenii_PYR-1       VTAGGTREPIDPVRFIGNRSSGKQGYAMARVMAQRGADVTLIAGNTSGLI
MSMEG_3054|M.smegmatis_MC2_155      VTAGGTREPLDPVRFIGNRSSGKQGYAVARVLAQRGADVTLIAGNTAGLI
TH_0823|M.thermoresistible__bu      VTAGGTREPIDPVRFIGNRSSGKQGYAMARVMAQRGAEVKLIAGNTAGLV
MMAR_2204|M.marinum_M               VTAGGTREPIDPVRFVGNRSSGKQGYAVARVAAQRGAEVTLIAGHTTGLI
MUL_1790|M.ulcerans_Agy99           VTAGGTREPIDPVRFVGNRSSGKQGYAVARVAAQRGAEVTLIAGHTTGLI
MLBr_00543|M.leprae_Br4923          VTSGGTRESIDPVRFIGNRSSGKQGYAVARVAVQRGAEVTLIAGHTAGLT
Mb1426|M.bovis_AF2122/97            VTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIAGHTAGLV
Rv1391|M.tuberculosis_H37Rv         VTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIAGHTAGLV
MAV_3383|M.avium_104                VTAGGTREPVDPVRFIGNRSSGKQGYAVARVAAQRGAEVTLIAGHTAGLI
MAB_2821c|M.abscessus_ATCC_199      VTAGGTREPLDPVRFIGNRSSGKQGYAIARVAAQRGAEVTLIAGHTVGLP
                                    **:*****.:*****:***********:*** .****:*.****:* ** 

Mflv_3738|M.gilvum_PYR-GCK          DPAGVHVVHVGSATQLRDAVSKHAPDANVLVMAAAVADFRPAHPATSKIK
Mvan_2669|M.vanbaalenii_PYR-1       DPAGVHVTHVGSAAQLRDAVSKHAPDANVLVMAAAVADFRPAHPAVNKIK
MSMEG_3054|M.smegmatis_MC2_155      DPAGVEMVHIGSATQLRDAVSKHAPDANVLVMAAAVADFRPAHVAAAKIK
TH_0823|M.thermoresistible__bu      DPAGVEVSHVGSAAQMRDAVNKAAPEAHVLVMAAAVADFRPAHPAETKIK
MMAR_2204|M.marinum_M               DPAGVEVVHVSTAQQLDDAVSKHAPTADVLVMAAAVADFRPAQVSTAKIK
MUL_1790|M.ulcerans_Agy99           DPAGVEVVHVSTAQQLDDAVSKHAPTADVLVMAAAVADFRPAQVSTAKIK
MLBr_00543|M.leprae_Br4923          NPAGVDVVHVGSAQQLGDAVSKHAPDFDVLVMAAAVADFRPAQVATAKIK
Mb1426|M.bovis_AF2122/97            DPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIK
Rv1391|M.tuberculosis_H37Rv         DPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIK
MAV_3383|M.avium_104                DPAGVEVVHVSSAAQLGDAVSKRAPEADVLVMAAAVADFRPAHVAAAKIK
MAB_2821c|M.abscessus_ATCC_199      DPAGVEVVHISSAAQLQDAVTKHAPAAEALIMAAAVADFRPAHVATSKIK
                                    :****.: *:.:* *: ***.* **  ..*:***********: :  ***

Mflv_3738|M.gilvum_PYR-GCK          KGPDATTDP--AIELIRNDDVLAGAVRARDDGQLPNMAAIVGFAAETGDA
Mvan_2669|M.vanbaalenii_PYR-1       KGPAGEGEP--TIELVRNDDVLAGAVRARADGQLPNMQAIVGFAAETGDA
MSMEG_3054|M.smegmatis_MC2_155      KG--ASEPS--SIDLVRNDDVLAGAVRARADGQLPNMRAIVGFAAETGDA
TH_0823|M.thermoresistible__bu      KSSDPNAPA-PVIELTRTDDVLAGVVRSRADGQLPNMRAIVGFAAETGDA
MMAR_2204|M.marinum_M               KTADSP----PVIELLRNDDVLAGAVRAREDGQLPKMRAIVGFAAETGDA
MUL_1790|M.ulcerans_Agy99           KTADSP----PVIELLRNDDVLAGAVRAREDGQLPKMRAIVGFAAETGDA
MLBr_00543|M.leprae_Br4923          KGPDDQDE--PLIELVYNEDVLAAAVRARTHGQLPNMRAIVGFAAETGDA
Mb1426|M.bovis_AF2122/97            KGVEGP----PTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDA
Rv1391|M.tuberculosis_H37Rv         KGVEGP----PTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDA
MAV_3383|M.avium_104                KSASNETAP-PTIELVRNDDVLAGAVRARAHGQLPNMRAIVGFAAETGDA
MAB_2821c|M.abscessus_ATCC_199      KSHGAAGENDAPIELLRNADVLAGVVRARADGQLPKMRAIVGFAAETGDA
                                    *           *:*  . ****..**:* .****:* ************

Mflv_3738|M.gilvum_PYR-GCK          NGDVLFHARAKLTRKGCDLLVVNAVGENRAFEVDHNDGWLLSS----DGS
Mvan_2669|M.vanbaalenii_PYR-1       NGDVLFHARAKLRRKGCDLLVVNAVGENRAFEVDHNDGWLLSA----DGT
MSMEG_3054|M.smegmatis_MC2_155      NGDVLFHARAKLERKGCDLLVVNAVGENRAFEVDHNDGWLLSA----DGT
TH_0823|M.thermoresistible__bu      SGDVLHHARAKLKRKGCDLLVVNAVGENRAFEVEDNAGWLLAA----DGA
MMAR_2204|M.marinum_M               NGDVLFHARQKLRRKSCDLLVVNAVGGDRAFEVDNNDGWLLAA----DGT
MUL_1790|M.ulcerans_Agy99           NGDVLFHARQKLRRKGCDLLVVNAVGGDRAFEVDNNDGWLLAA----DGT
MLBr_00543|M.leprae_Br4923          SGDVLFHARAKLRRKGCDLLVVNAVGDGRAFEVDNNDGWLLAS----DGT
Mb1426|M.bovis_AF2122/97            NGDVLFHARAKLRRKGCDLLVVNAVGEGRAFEVDSNDGWLLAS----DGT
Rv1391|M.tuberculosis_H37Rv         NGDVLFHARAKLRRKGCDLLVVNAVGEGRAFEVDSNDGWLLAS----DGT
MAV_3383|M.avium_104                SGDVLFHARAKLQRKGCDLLVVNAVGEGRAFEVDSNDGWLLAS----DGT
MAB_2821c|M.abscessus_ATCC_199      NGDVLFHARAKLKRKGCDLLVVNAVGEGRAFEVDSNDGWLLSAQSGGDIT
                                    .****.*** ** **.********** .*****: * ****::    * :

Mflv_3738|M.gilvum_PYR-GCK          ESALEHGSKTVIASRIVDAIAAFLHS---GAG-
Mvan_2669|M.vanbaalenii_PYR-1       ESALEHGSKTVIASRIVDAIAAFLRT---CA--
MSMEG_3054|M.smegmatis_MC2_155      ESALEHGSKTLMATRIVDSIAAFLKS---QDG-
TH_0823|M.thermoresistible__bu      ESQLEHGSKTLMASRIVDAIAAFLQT---SGSA
MMAR_2204|M.marinum_M               EAALQHGSKTLMASRIVDAIVTFLD---SCRG-
MUL_1790|M.ulcerans_Agy99           EAALQHGSKTLMASRIVDAIVTFLD---SCRG-
MLBr_00543|M.leprae_Br4923          ELALQHGSKMLMASRIVDGIVTFLHGLPDLRGG
Mb1426|M.bovis_AF2122/97            ESALQHGSKTLMASRIVDAIVTFLAG---CSS-
Rv1391|M.tuberculosis_H37Rv         ESALQHGSKTLMASRIVDAIVTFLAG---CSS-
MAV_3383|M.avium_104                ESALQHGSKTLMASRIVDAIAAFLHG---DSG-
MAB_2821c|M.abscessus_ATCC_199      EVVLEHGTKVLMASRIVDAVAGLCQ--------
                                    *  *:**:* ::*:****.:. :