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M. thermoresistible (build 8) TH_0821 (gmk)

annotation: PROBABLE GUANYLATE KINASE GMK
coordinates: 1707022 - 1707444
length: 141

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0821gmk-100% (141)PROBABLE GUANYLATE KINASE GMK

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1424gmk4e-5674.64% (138) guanylate kinase
M. gilvum PYR-GCKMflv_3740gmk1e-5978.26% (138) guanylate kinase
M. tuberculosis H37RvRv1389gmk4e-5674.64% (138) guanylate kinase
M. leprae Br4923MLBr_00541gmk1e-5574.64% (138) guanylate kinase
M. abscessus ATCC 19977MAB_2823c-6e-5165.94% (138) guanylate kinase
M. marinum MMMAR_2202gmk1e-5673.91% (138) guanylate kinase Gmk
M. avium 104MAV_3385gmk2e-5777.54% (138) guanylate kinase
M. smegmatis MC2 155MSMEG_3051gmk1e-6078.42% (139) guanylate kinase
M. ulcerans Agy99MUL_1788gmk2e-5673.19% (138) guanylate kinase
M. vanbaalenii PYR-1Mvan_2667gmk6e-5776.09% (138) guanylate kinase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3740|M.gilvum_PYR-GCK          --MSEGRGPD--------SASGATVLVLSGPSAVGKSTVVRCLRERVADL
Mvan_2667|M.vanbaalenii_PYR-1       --MNEGGGPD--------SATGAAVLVLSGPSAVGKSTVVRCLRERVEDL
TH_0821|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3051|M.smegmatis_MC2_155      --MTVGRGAG---QRATDGPARARVVVLSGPSAVGKSTVVRCLRERLPDL
Mb1424|M.bovis_AF2122/97            --MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNL
Rv1389|M.tuberculosis_H37Rv         --MSVGEGPDTKPTARGQPAAVGRVVVLSGPSAVGKSTVVRCLRERIPNL
MMAR_2202|M.marinum_M               -------------MSAGGGPGTGHVVVLSGPSAVGKSTVVRCLRERIPNL
MUL_1788|M.ulcerans_Agy99           --MPGGGADSGAPMSAGGGPGTGHVVVLSGPSAVGKSTVVRCLRERIPNL
MLBr_00541|M.leprae_Br4923          MPVSARGAPDAEHWAWSEQTDKGRVVVLSGPSAVGKSTVVRCLRERVSNL
MAV_3385|M.avium_104                ------------------------MVVLSGPSAVGKSTVVRCLRERVPNL
MAB_2823c|M.abscessus_ATCC_199      ---------------------------------------MRRLRDEVDGL
                                                                                      

Mflv_3740|M.gilvum_PYR-GCK          YFSVSVTTRAPRPGEVDGVDYFFVTPERFQQLIDDNALLEWADIHGGLHR
Mvan_2667|M.vanbaalenii_PYR-1       FFSVSVTTRAPRPGEVDGVDYFFVTAEQFQQLIDEGALLEWAEIHGGLHR
TH_0821|M.thermoresistible__bu      ---------------VDGVDYSFISPERFAELIDSGELLEWAEIHGGLHR
MSMEG_3051|M.smegmatis_MC2_155      YFSVSVTTRAPRPGEVDGVDYTFVSPERFQQLIDDGELLEWAEIHGGLHR
Mb1424|M.bovis_AF2122/97            HFSVSATTRAPRPGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHR
Rv1389|M.tuberculosis_H37Rv         HFSVSATTRAPRPGEVDGVDYHFIDPTRFQQLIDQGELLEWAEIHGGLHR
MMAR_2202|M.marinum_M               HFSVSATTRAPRPGEVDGVDYHFVTPESFQQMIDQGELLEWAEIHGGLHR
MUL_1788|M.ulcerans_Agy99           HFSVSATTRAPRPGEVDGVDYHFVTPESFQQMIDQGELLEWAEIHGGLHR
MLBr_00541|M.leprae_Br4923          HFSVSATTREPRPDEMDGVDYHFVSPARFQQLIDQGALLEWAEIHGGMHR
MAV_3385|M.avium_104                HFSVSATTRAPRPGEVDGVDYHFVSPARFQQLIDEGALLEWAEIHSGLHR
MAB_2823c|M.abscessus_ATCC_199      FFSVSATTRAPRPGEVDGVDYHFVTAEEFQRLIDTDALLEWADIHGGLQR
                                                   :***** *: .  * .:** . *****:**.*::*

Mflv_3740|M.gilvum_PYR-GCK          SGTPAAPVREAAAAGRPVLIEVDLAGARAVKKAMPEATSVFLAPPSWETL
Mvan_2667|M.vanbaalenii_PYR-1       SGTPAAPVRAAAAAGHPVLIEVDLAGARAVKKAMPEATTVFLAPPSWEVL
TH_0821|M.thermoresistible__bu      SGTPAEPIRRAVKDGRPVLIEVDLAGARAVKAAMPEAMTVFVAPPDWQTL
MSMEG_3051|M.smegmatis_MC2_155      SGTPAAPVREATRAGRPVLIEVDLAGARAVKQAMPEVVSVFLAPPSWDEL
Mb1424|M.bovis_AF2122/97            SGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDL
Rv1389|M.tuberculosis_H37Rv         SGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDL
MMAR_2202|M.marinum_M               SGTPAQPVREATASGVPVLIEVDLAGARAVKKAMPEAISVFLAPPSWEDL
MUL_1788|M.ulcerans_Agy99           SGTPAQPVREATASGVPVLIEVDLAGGRAVKKAMPEAISVFLAPPSWEDL
MLBr_00541|M.leprae_Br4923          SGTLAEPVRVAAAAGFPVLIEVDLAGARAVKKAMPEAIAVFLAPPSWEDL
MAV_3385|M.avium_104                SGTLAAPVRAAVARGCPVLIEVDLAGARAVKKAMPEALTVFLAPPSWEDL
MAB_2823c|M.abscessus_ATCC_199      SGTPAAPVREAMEAGRPTLIEVDLAGARAIKAALPQALAVFLAPPSWEAL
                                    *** * *:* *   * *.********.**:* ::*:. :**:***.*: *

Mflv_3740|M.gilvum_PYR-GCK          ESRLIGRGTETPEVIARRLETARAELAAQDDFDEIVVNSQLESACAELVA
Mvan_2667|M.vanbaalenii_PYR-1       ESRLVGRGTETPDVIARRLQTARDELAAQGDFDEVVVNGQLESACAELVS
TH_0821|M.thermoresistible__bu      EERLVGRGTETPEVIARRLDTARAELAAQSEFDRIVVNSDLETACAELVS
MSMEG_3051|M.smegmatis_MC2_155      VRRLSGRGTETPEVMARRLDTARAEMAAQSDFDRVVVNRQLDSACAELVS
Mb1424|M.bovis_AF2122/97            QARLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESACAELVS
Rv1389|M.tuberculosis_H37Rv         QARLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESACAELVS
MMAR_2202|M.marinum_M               KARLVGRGTETPDVIRRRLQTAQTELAAQPDFDKVVVNGRLESACAELVS
MUL_1788|M.ulcerans_Agy99           KARLVGRGTETPDVIRRRLQTAQTELAAQRDFDKVVVNGRLESACAELVS
MLBr_00541|M.leprae_Br4923          EARLVGRGTETPEAIRRRLETARIELAAQDDFDEVVVNRRLESACAELVS
MAV_3385|M.avium_104                EARLIGRGTETPEVIARRLQTARVEMAAQHDFDRVVVNSRLESACAELVS
MAB_2823c|M.abscessus_ATCC_199      VDRLTGRGTESESVIARRLETATVEMAAQTDFDVVIVNDQLENACAKLVS
                                      ** *****: ..: ***:**  *:*** :** ::**  *:.***:**:

Mflv_3740|M.gilvum_PYR-GCK          LLVAHAPERRDQP------------
Mvan_2667|M.vanbaalenii_PYR-1       LLVAHTPVQHDQS------------
TH_0821|M.thermoresistible__bu      LLVDP--------------------
MSMEG_3051|M.smegmatis_MC2_155      LLVDS--------------------
Mb1424|M.bovis_AF2122/97            LLVGTAPG----SP-----------
Rv1389|M.tuberculosis_H37Rv         LLVGTAPG----SP-----------
MMAR_2202|M.marinum_M               LLVRTVPG----SG-----------
MUL_1788|M.ulcerans_Agy99           LLVRTVPG----SG-----------
MLBr_00541|M.leprae_Br4923          LLVGAVSG----SA-----------
MAV_3385|M.avium_104                LLVGTAPDRHDTSGRTGRQSTSHPD
MAB_2823c|M.abscessus_ATCC_199      LLVGR--------------------
                                    ***