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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0815 | pyrC | - | 100% (136) | PROBABLE DIHYDROOROTASE PYRC (DHOase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1416 | pyrC | 1e-61 | 84.73% (131) | dihydroorotase |
| M. gilvum PYR-GCK | Mflv_3746 | pyrC | 4e-60 | 83.33% (132) | dihydroorotase |
| M. tuberculosis H37Rv | Rv1381 | pyrC | 1e-61 | 84.73% (131) | dihydroorotase |
| M. leprae Br4923 | MLBr_00533 | pyrC | 3e-60 | 81.06% (132) | dihydroorotase |
| M. abscessus ATCC 19977 | MAB_2830c | pyrC | 1e-63 | 83.58% (134) | dihydroorotase |
| M. marinum M | MMAR_2196 | pyrC | 4e-63 | 86.36% (132) | dihydroorotase PyrC |
| M. avium 104 | MAV_3392 | pyrC | 6e-62 | 85.50% (131) | dihydroorotase |
| M. smegmatis MC2 155 | MSMEG_3044 | pyrC | 3e-62 | 82.22% (135) | dihydroorotase |
| M. ulcerans Agy99 | MUL_1781 | pyrC | 3e-63 | 86.36% (132) | dihydroorotase |
| M. vanbaalenii PYR-1 | Mvan_2661 | pyrC | 9e-59 | 82.44% (131) | dihydroorotase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00533|M.leprae_Br4923 MS------------VLLRGVRLYGEGEQVDVLVEGEQIANIGAGIDIP--
MAV_3392|M.avium_104 MS------------VLLRGVRLYGEGDRVDVLVDDGQIADIGAGLDIP--
Mb1416|M.bovis_AF2122/97 MS------------VLIRGVRPYGEGERVDVLVDDGQIAQIGPDLAIP--
Rv1381|M.tuberculosis_H37Rv MS------------VLIRGVRPYGEGERVDVLVDDGQIAQIGPDLAIP--
MMAR_2196|M.marinum_M MS------------VLLRGVRLYGEGERVDVLVDDNQIADIGTGLAIP--
MUL_1781|M.ulcerans_Agy99 MS------------VLLRGVRLYGEGERVDVLVDDNQIADIGTGLAIP--
Mflv_3746|M.gilvum_PYR-GCK MS------------VVLKSVRLYGEGDAVDVLVRDGIIAEIGTGLSA---
Mvan_2661|M.vanbaalenii_PYR-1 MTSSSPESLRSCPPIVLKSVRLYGEGDPVDVLVRDGQIAEIGERLTAP--
MSMEG_3044|M.smegmatis_MC2_155 MRDHN-----STAPVLIRGVKPYGEGDPVDVLVDDGQIARIGADLPVP--
TH_0815|M.thermoresistible__bu --------------------------------------------------
MAB_2830c|M.abscessus_ATCC_199 MS------------VLIKGVLLYGEGDQVDVLIEDGQITRIEAGIGAGIE
MLBr_00533|M.leprae_Br4923 -DTADVIDAIDQVLLPGLVDLHTHLREPGREYAEDIETGSAAAALGGYTA
MAV_3392|M.avium_104 -DTADVIDATGQVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTA
Mb1416|M.bovis_AF2122/97 -DTADVIDATGHVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTA
Rv1381|M.tuberculosis_H37Rv -DTADVIDATGHVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTA
MMAR_2196|M.marinum_M -DTADVIDATDHVLLPGLVDLHTHLREPGREYAEDIETGSAAAALGGYTA
MUL_1781|M.ulcerans_Agy99 -DTADVIDATDHVLLPGLVDLHTHLREPGREYAEDIETGSAAAALGGYTA
Mflv_3746|M.gilvum_PYR-GCK ---DETIDCTGRVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTA
Mvan_2661|M.vanbaalenii_PYR-1 -TDADSIDCEGKILLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTA
MSMEG_3044|M.smegmatis_MC2_155 -ETADVIDARGQVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTA
TH_0815|M.thermoresistible__bu --------------------------------------------------
MAB_2830c|M.abscessus_ATCC_199 TEVDTAIEAPGQILLPGFVDLHTHLREPGREDTETIDSGSAAAALGGYTA
MLBr_00533|M.leprae_Br4923 VFAMPNTTPVADSPVVTDHVWRRGQQVGLVDVHPVGAVTVGLAGAELTEM
MAV_3392|M.avium_104 VFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTMGLAGKELTEM
Mb1416|M.bovis_AF2122/97 VFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGAELTEM
Rv1381|M.tuberculosis_H37Rv VFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGAELTEM
MMAR_2196|M.marinum_M VFAMANTHPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGTELTEM
MUL_1781|M.ulcerans_Agy99 VFAMANTHPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTIGLAGTELTEM
Mflv_3746|M.gilvum_PYR-GCK VFAMANTDPVADSVVVTDHVWQRGQQVGLVDVHPVGAVTVGLAGKQLTEM
Mvan_2661|M.vanbaalenii_PYR-1 VFAMANTDPVADSAVVTDHVWHRGQQVGLVDVHPVGAVTVGLDGKQLTEM
MSMEG_3044|M.smegmatis_MC2_155 VFAMANTDPVADTVVVTDHVWRRGQEVGLVDVHPVGAITMGLKGAQLTEM
TH_0815|M.thermoresistible__bu --------------------------------------------------
MAB_2830c|M.abscessus_ATCC_199 VFAMANTNPVADSPVVTDHVWQRGQQVGIVDVHPVGAVTVGLEGKQLTEM
MLBr_00533|M.leprae_Br4923 GMMAAGAAQVRIFSDDGNCVHNPLVMRRALEYATGLGVLIAQHAEEPRLT
MAV_3392|M.avium_104 GMMAAGAAQVRMFSDDGVCVHDPLVMRRALEYATGLGVLIAQHAEEPRLT
Mb1416|M.bovis_AF2122/97 GMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLT
Rv1381|M.tuberculosis_H37Rv GMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLT
MMAR_2196|M.marinum_M GMMNAGVAAVRMFSDDGICVHDPLIMRRALEYATGLGVLIAQHAEEPRLT
MUL_1781|M.ulcerans_Agy99 GMMNAGVAAVRMFSDDGICVHDPLIMRRALEYATGLGVLIAQHAEEPRLT
Mflv_3746|M.gilvum_PYR-GCK GLMAAGTGRVRMFSDDGVCVDDPLLMRRALEYASGLGVLIAQHAEEPRLT
Mvan_2661|M.vanbaalenii_PYR-1 GLMAAGAGQVRMFSDDGVCVDDPLVMRRALEYASGLGVLIAQHAEEPRLT
MSMEG_3044|M.smegmatis_MC2_155 GLMAAGAGQVRMFSDDGVCVENPLVMRRALEYATGLGVLIAQHAEEPRLT
TH_0815|M.thermoresistible__bu --------------------------------------------------
MAB_2830c|M.abscessus_ATCC_199 AMMARGAGRVRMFSDDGKCVHDPLVMRRALEYAKGLGVLIAQHAEEPRLT
MLBr_00533|M.leprae_Br4923 VGAVAHEGPTAARLGLSGWPRAAEESIVARDALLARDAGARVHICHASTA
MAV_3392|M.avium_104 VGAVAHEGPTAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTA
Mb1416|M.bovis_AF2122/97 VGAFAHEGPMAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASAA
Rv1381|M.tuberculosis_H37Rv VGAVAHEGPMAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASAA
MMAR_2196|M.marinum_M VGAVAHEGPNAAQLGLAGWPRAAEESIVARDALLARDAGARVHICHASTV
MUL_1781|M.ulcerans_Agy99 VGAVAHEGPSAAQLGLAGWPRAAEESIVARDALLTRDAGARVHICHASTV
Mflv_3746|M.gilvum_PYR-GCK VGAVAHEGPNAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTA
Mvan_2661|M.vanbaalenii_PYR-1 VGAVAHEGPNAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTA
MSMEG_3044|M.smegmatis_MC2_155 VGAVAHEGPIAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTA
TH_0815|M.thermoresistible__bu --------------------------------------------------
MAB_2830c|M.abscessus_ATCC_199 VGSVAHEGANAARLGLTGWPRAAEESIVARDAILSRDTGAPVHICHASTA
MLBr_00533|M.leprae_Br4923 GTVEILKWAKEQGISITAEVTPHHLLLDDSRLASYDGVNRVNPPLRETAD
MAV_3392|M.avium_104 GTVEIVKWAKQQGISITAEVTPHHLMLDDSRLASYDGRNRVNPPLREAAD
Mb1416|M.bovis_AF2122/97 GTVEILKWAKDQGISITAEVTPHHLLLDDARLASYDGVNRVNPPLREASD
Rv1381|M.tuberculosis_H37Rv GTVEILKWAKDQGISITAEVTPHHLLLDDARLASYDGVNRVNPPLREASD
MMAR_2196|M.marinum_M GTVEILKWAKSQGISITAEVTPHHLLLDDRRLSGYDGVNRVNPPLREASD
MUL_1781|M.ulcerans_Agy99 GTVEILKWAKSQGISITAEVTPHHLLLDDRRLSGYDGVNRVNPPLREASD
Mflv_3746|M.gilvum_PYR-GCK GTVELVRWAKEQGIAITAEVTPHHLLLDDTRLETYDGRNRVNPPLREVSD
Mvan_2661|M.vanbaalenii_PYR-1 GTVELLKWAKSQGISITAEVTPHHLLLDDSRLDTYDGVNRVNPPLREVSD
MSMEG_3044|M.smegmatis_MC2_155 GTVELLKWAKAQGISITAEVTPHHLLLDDSRLETYDGRNRVNPPLREAED
TH_0815|M.thermoresistible__bu --------------------------------------------------
MAB_2830c|M.abscessus_ATCC_199 GTVELLKWAKGQGISITAEVTPHHLLLDDGRLSSYDGVYRVNPPLRESSD
MLBr_00533|M.leprae_Br4923 AVALRQALADGIIDCVTTDHAPHADHEKCVEFSAARPGMLGLQTALSVVV
MAV_3392|M.avium_104 AAALRRALADGVIDCVATDHAPHAEHEKCVEFSAARPGMLGLQTALSIVV
Mb1416|M.bovis_AF2122/97 AVALRQALADGIIDCVATDHAPHAEHEKCVEFAAARPGMLGLQTALSVVV
Rv1381|M.tuberculosis_H37Rv AVALRQALADGIIDCVATDHAPHAEHEKCVEFAAARPGMLGLQTALSVVV
MMAR_2196|M.marinum_M AMALRQALADGIIDCVATDHAPHAEHEKCVEFSAARPGMLGLQTALSVVV
MUL_1781|M.ulcerans_Agy99 AMALRQALADGIIDCVATDHAPHAEHEKCVEFSAARPGMLGLQTALSVVV
Mflv_3746|M.gilvum_PYR-GCK TLALRQALADGVIDCVATDHAPHGEHEKMCEFANARPGMLGLQTALSVVV
Mvan_2661|M.vanbaalenii_PYR-1 AVALRRALADGVIDCVATDHAPHGAHEKCCEFANARPGMLGLQTALSVVV
MSMEG_3044|M.smegmatis_MC2_155 AAALRQALADGVIDCVATDHAPHAEHEKCCEFSVARPGMLGLQTALSVVV
TH_0815|M.thermoresistible__bu -----------VIDCVATDHAPHAEHEKMCEFAAARPGMLGLQTALSVVV
MAB_2830c|M.abscessus_ATCC_199 AAALRQALADGVIDCVATDHAPHADHEKCCEFAAARPGMLGLQTALSVVV
:****:******. *** **: *************:**
MLBr_00533|M.leprae_Br4923 HTMVVPGLLSWRDVAQVMSENPARIAGLPDHGRPLEVGEPANLTVVDPDV
MAV_3392|M.avium_104 HTMVRPGLLTWRDVAKVMSENPARIANLPDHGRPLEVGEPANLTVVDPDA
Mb1416|M.bovis_AF2122/97 QTMVAPGLLSWRDIARVMSENPACIARLPDQGRPLEVGEPANLTVVDPDA
Rv1381|M.tuberculosis_H37Rv QTMVAPGLLSWRDIARVMSENPACIARLPDQGRPLEVGEPANLTVVDPDA
MMAR_2196|M.marinum_M QTMVQPGLLSWRDVARVMSENPARIVGLPDHGRPLEVGEPANLTVIDPDA
MUL_1781|M.ulcerans_Agy99 QTMVQPGLLSWRDVARVMSENPARIVGLPDHGRPLEVGEPANLTVIDPDA
Mflv_3746|M.gilvum_PYR-GCK ETMVQPGPLTWRDVARVMSEAPARIVGLPDQGRPLEVGEPANLTVVDPDA
Mvan_2661|M.vanbaalenii_PYR-1 ETLVNPGLLTWRDVARVMSEAPARIVGLPDQGRPLEVGEPANLTVVDPAA
MSMEG_3044|M.smegmatis_MC2_155 ETMVRPGLLTWRGVAKVMSEAPAAIVGLPDQGRPLEVGEPANLTVVDPDA
TH_0815|M.thermoresistible__bu QTMVTPGLLDWRGVARVMSENPARIVGLPDQGRPLEVGEPANLTVVDPDA
MAB_2830c|M.abscessus_ATCC_199 QTMVRPGLLTWRDIARVMSERPAQIVGLPDQGRPIAVGEPANLTIVDPDA
.*:* ** * **.:*:**** ** *. ***:***: ********::** .
MLBr_00533|M.leprae_Br4923 TWTVTGDGLASRSANTPYEAMTLPATVTATLLRGKVTARGQKSPV-----
MAV_3392|M.avium_104 SWTVAGSDLASRSANTPYEAMTLPATVTATLLRGKVTARDGKCPV-----
Mb1416|M.bovis_AF2122/97 TWTVTGADLASRSANTPFESMSLPATVTATLLRGKVTARDGKIRA-----
Rv1381|M.tuberculosis_H37Rv TWTVTGADLASRSANTPFESMSLPATVTATLLRGKVTARDGKIRA-----
MMAR_2196|M.marinum_M TWTVTGADLASRSANTPYESMTLPARVTATLLRGKITARDGKSPA-----
MUL_1781|M.ulcerans_Agy99 TWTVTGADLASRSANTPYESMTLPARVTATLLRGKITARDGKSPA-----
Mflv_3746|M.gilvum_PYR-GCK RWTVSGPALASRSDNTPYEAMELPGVVTATLLRGTVTARDGKAGA-----
Mvan_2661|M.vanbaalenii_PYR-1 RWTVKGPELASRSDNTPYEDMELPAVVTATLLRGKVTARDGKVGA-----
MSMEG_3044|M.smegmatis_MC2_155 TWTVAGTELASRSDNTPFETMTLPATVTATLLRGRVTARDGKSAAAGGGS
TH_0815|M.thermoresistible__bu SWVVEGSGLASRSANTPYESMTLPATVTLTMLRGKITARDGKAATS----
MAB_2830c|M.abscessus_ATCC_199 SWTVSGDGLASKSANTPFESMTLPATVTATLLRGRITARDGRVASMSHLC
*.* * ***:* ***:* * **. ** *:*** :***. :
MLBr_00533|M.leprae_Br4923 ------
MAV_3392|M.avium_104 ------
Mb1416|M.bovis_AF2122/97 ------
Rv1381|M.tuberculosis_H37Rv ------
MMAR_2196|M.marinum_M ------
MUL_1781|M.ulcerans_Agy99 ------
Mflv_3746|M.gilvum_PYR-GCK ------
Mvan_2661|M.vanbaalenii_PYR-1 ------
MSMEG_3044|M.smegmatis_MC2_155 VQ----
TH_0815|M.thermoresistible__bu ------
MAB_2830c|M.abscessus_ATCC_199 DEDLAQ