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M. thermoresistible (build 8) TH_0719 (-)

annotation: HpcH/HpaI aldolase/citrate lyase family protein
coordinates: 1540691 - 1541509
length: 273

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0719--100% (273)HpcH/HpaI aldolase/citrate lyase family protein
M. thermoresistible (build 8)TH_3034-3e-1327.12% (236) PUTATIVE Citrate (pro-3S)-lyase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2526ccitE2e-9062.17% (267) citrate (Pro-3S)-lyase beta subunit
M. gilvum PYR-GCKMflv_2556-1e-11981.44% (264) HpcH/HpaI aldolase
M. tuberculosis H37RvRv2498ccitE2e-9062.17% (267) citrate (Pro-3S)-lyase beta subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4378c-1e-11476.78% (267) putative citrate lyase beta subunit
M. marinum MMMAR_3845citE9e-9263.30% (267) citrate (pro-3s)-lyase (beta subunit) CitE
M. avium 104MAV_1674-2e-9565.40% (263) CitE protein
M. smegmatis MC2 155MSMEG_4713-1e-11174.17% (271) HpcH/HpaI aldolase/citrate lyase family protein
M. ulcerans Agy99MUL_3776citE6e-9062.17% (267) citrate (pro-3s)-lyase (beta subunit) CitE
M. vanbaalenii PYR-1Mvan_4087-1e-12282.40% (267) HpcH/HpaI aldolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2556|M.gilvum_PYR-GCK          MTL-APGTAWLFCPADRPERFEKAAAAADIVILDLEDGVAAKDRQAAREA
Mvan_4087|M.vanbaalenii_PYR-1       MTL-AAGPAWLFCPADRPERFEKAAAAADVVILDLEDGVAAKDREAARKA
TH_0719|M.thermoresistible__bu      MDLSAVGPAWLFCPADRPERFEKAAAAADVVILDLEDGVAAKDRPAAREA
MAB_4378c|M.abscessus_ATCC_199      MTVATAGPGWLFCPADRPERFEKAAVAADVVILDLEDGVAAADRPAARDA
MSMEG_4713|M.smegmatis_MC2_155      MGLATTGPAWLFCPADRPERFEKAAAAADVVILDLEDG--AGDKPAAREA
Mb2526c|M.bovis_AF2122/97           MNLRAAGPGWLFCPADRPERFAKAAAAADVVILDLEDGVAEAQKPAARNA
Rv2498c|M.tuberculosis_H37Rv        MNLRAAGPGWLFCPADRPERFAKAAAAADVVILDLEDGVAEAQKPAARNA
MMAR_3845|M.marinum_M               MKLRTAGPAWLFCPADRPERFAKAAAAADVVILDLEDGVAEAQKPAARQA
MUL_3776|M.ulcerans_Agy99           MKLRTASPAWLFCPADRPERFAKAAAAADVVILDLEDGVAEAQKPAARQA
MAV_1674|M.avium_104                MNPHAAGPAWLFCPADRPERFAKAAAAADVVILDLEDGVAEADKPAARKA
                                    *   : ...************ ***.***:********    :: ***.*

Mflv_2556|M.gilvum_PYR-GCK          LVNTPLDPARTVVRVNPTGTADHGPDLEAVARTAYTTVMLAKTEAPEQVR
Mvan_4087|M.vanbaalenii_PYR-1       LVDTPLDPSRTVVRVNPAGTPDHKLDLEALSRTSYTTVMLAKTESPQQVA
TH_0719|M.thermoresistible__bu      LLSTPLDPARTVVRVNPAGTADHRLDLDALTRTPYRTVMLAKTDAAEQVR
MAB_4378c|M.abscessus_ATCC_199      LISTPLDPGRTVVRLNPAATADHALDLEALAQTEYTTVILAKSEHADQVL
MSMEG_4713|M.smegmatis_MC2_155      LLSTPLDPARTVVRINPGDSPEQKLDLDVLSQTAYTTVMLPKCESAAQVT
Mb2526c|M.bovis_AF2122/97           LRDTPLDPERTVVRINAGGTADQARDLEALAGTAYTTVMLPKAESAAQVI
Rv2498c|M.tuberculosis_H37Rv        LRDTPLDPERTVVRINAGGTADQARDLEALAGTAYTTVMLPKAESAAQVI
MMAR_3845|M.marinum_M               LLDTPLDPERTIVRINAGDTDEQARDLAALAGTAYTTVMLPKAESAAQLA
MUL_3776|M.ulcerans_Agy99           LLDTPLDPERTIVRINAGDTDEQARDLAALAGTAYTTVMLPKAESVAQLA
MAV_1674|M.avium_104                LLETPLDPERTVVRVNAADTDEYARDLEALAGTAYTTVMLSKTESAAQVQ
                                    * .***** **:**:*.  : :   ** .:: * * **:*.* :   *: 

Mflv_2556|M.gilvum_PYR-GCK          ALAPLDVIVLIETPLGALNVVDLARVDNAYALMWGAEDLFAELGGTANRY
Mvan_4087|M.vanbaalenii_PYR-1       ALAPLDVVVLIETPLGALAVVELARVDNALALMWGAEDLFAVLGGTANRY
TH_0719|M.thermoresistible__bu      ALAPLQVVVLIETPLGALNVVESARADNAVAVMWGAEDLFAVTGGTDNRN
MAB_4378c|M.abscessus_ATCC_199      GLAPLNVVVLVETPMGALNVAELVRPGNVVAAMWGAEDLFAATWGTNNRW
MSMEG_4713|M.smegmatis_MC2_155      ALAPLEVVLIVETPLGALKVDEAAAAANTWGVMWGAEDLFGFLGGTNNRF
Mb2526c|M.bovis_AF2122/97           ELAPRDVIALVETARGAVCAAEIAAADPTVGMMWGAEDLIATLGGSSSRR
Rv2498c|M.tuberculosis_H37Rv        ELAPRDVIALVETARGAVCAAEIAAADPTVGMMWGAEDLIATLGGSSSRR
MMAR_3845|M.marinum_M               LLAPRDVIALVETARGALFAAEIAAADNTVGMMWGAEDLIATLGGSSSRR
MUL_3776|M.ulcerans_Agy99           LLAPRDVIALVETARGALFAAEIAAADNTVGMMWGAEDLIATLGGSSSRR
MAV_1674|M.avium_104                AMAPREVIALLETPRGAVFATEIAAAQNTVALMWGAEDLVATLGGSSSRR
                                     :** :*: ::**. **: . : .    . . *******..   *: .* 

Mflv_2556|M.gilvum_PYR-GCK          PDGSYREVARHVRSQTLLAAKAYGRVALDSVFLDIKNLDGLRGEVDDAVA
Mvan_4087|M.vanbaalenii_PYR-1       PDGSYREVARHVRSQTLLAAKAYGRLALDSVFLDIKNLDGLRAEVDDAVA
TH_0719|M.thermoresistible__bu      PDGSYRDVARHVRSQSLLAAKAHGRLALDSVYLDIKDLDGLRAEVDDAVA
MAB_4378c|M.abscessus_ATCC_199      PDGSYRDVAQHVRSQTLLAAKAFGRIALDAVYLDIKALDGLRAEADDAVA
MSMEG_4713|M.smegmatis_MC2_155      PDDSYRDVAKYVRSRSLLAAKAFGKQALDSVYIDIRNLDGLRAEVDDAVA
Mb2526c|M.bovis_AF2122/97           ADGAYRDVARHVRSTILLAASAFGRLALDAVHLDILDVEGLQEEARDAAA
Rv2498c|M.tuberculosis_H37Rv        ADGAYRDVARHVRSTILLAASAFGRLALDAVHLDILDVEGLQEEARDAAA
MMAR_3845|M.marinum_M               GDGSYRDVARHVRSTTLLAASAFGRLALDAVHLDIGDIDGLHAEAIDAAT
MUL_3776|M.ulcerans_Agy99           GDGTYRDVARHVRSTILLAASAFGRLALDAVHLDIGDVDGLHAEAMDAAT
MAV_1674|M.avium_104                ADGSYRDVAHHVRSTALLTASAFGRAALDAVHLDIRDLDGLRAEAEDAVA
                                     *.:**:**::***  **:*.*.*: ***:*.:**  ::**: *. **.:

Mflv_2556|M.gilvum_PYR-GCK          VGFDGKVAIHPTQLPVIRDGYTPTEAQADWARRVLAAAQAERGVFQYEGQ
Mvan_4087|M.vanbaalenii_PYR-1       VGFDVKVAIHPSQVAVIRSGYAPTDAEVDWARRVLDTARTQRGVFAFEGI
TH_0719|M.thermoresistible__bu      VGFDAKVAIHPTQVAVIREGYTPTPDQVRWARHVLAAARDERGVFQFEGI
MAB_4378c|M.abscessus_ATCC_199      VGFDAKVAIHPTQVNVIRAAYEPTAKQVYWARGVLELAGRERGVFQFEGV
MSMEG_4713|M.smegmatis_MC2_155      VGFDIKVAIHPSQVAVIREGYMPTPEQARWAREVLAAAETQPGAFAFEGM
Mb2526c|M.bovis_AF2122/97           VGFDVTVCIHPSQIPVVRKAYRPSHEKLAWARRVLAASRSERGAFAFEGQ
Rv2498c|M.tuberculosis_H37Rv        VGFDVTVCIHPSQIPVVRKAYRPSHEKLAWARRVLAASRSERGAFAFEGQ
MMAR_3845|M.marinum_M               VGFDVTVCIHPSQVEVVRKAYRPDEEKLAWARRVLVAARTERGVFAFEGQ
MUL_3776|M.ulcerans_Agy99           VGFDVTVCIHPSQVEVVRKAYRPDEEKLAWARRVLVAARTERGVFAFEGQ
MAV_1674|M.avium_104                LGFAGTVCIHPSQVPVVRQAYRPPEEKLDWARRVLAAARSERGVFAFEGQ
                                    :**  .*.***:*: *:* .* *   :  *** **  :  : *.* :** 

Mflv_2556|M.gilvum_PYR-GCK          MVDMPVLRRAERIVALAP-------
Mvan_4087|M.vanbaalenii_PYR-1       MVDAPVLRRAERIVELAPHPGA---
TH_0719|M.thermoresistible__bu      MVDAPVLRRAERIVQLAPDPGR---
MAB_4378c|M.abscessus_ATCC_199      MVDAPVLRRAERIIQLSALTGGLCE
MSMEG_4713|M.smegmatis_MC2_155      MVDAPVLRRAERIAALAPDNG----
Mb2526c|M.bovis_AF2122/97           MVDSPVLTHAETMLRRAGEATSE--
Rv2498c|M.tuberculosis_H37Rv        MVDSPVLTHAETMLRRAGEATSE--
MMAR_3845|M.marinum_M               MVDSPVLRHAEMLLRRAGESVPA--
MUL_3776|M.ulcerans_Agy99           MVDSPVLRHAEMLLRRAGESVPA--
MAV_1674|M.avium_104                MVDSPVLKHAQMMLRRAGETDAG--
                                    *** *** :*: :   :